WO2002015821A1 - Extenseur deployable comportant plusieurs modules de cellules de deploiement - Google Patents

Extenseur deployable comportant plusieurs modules de cellules de deploiement Download PDF

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Publication number
WO2002015821A1
WO2002015821A1 PCT/US2000/023227 US0023227W WO0215821A1 WO 2002015821 A1 WO2002015821 A1 WO 2002015821A1 US 0023227 W US0023227 W US 0023227W WO 0215821 A1 WO0215821 A1 WO 0215821A1
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WO
WIPO (PCT)
Prior art keywords
cell
expansion
stent
ring
interconnected
Prior art date
Application number
PCT/US2000/023227
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English (en)
Original Assignee
Stenttech, Inc. Dba Stenttech
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Stenttech, Inc. Dba Stenttech filed Critical Stenttech, Inc. Dba Stenttech
Priority to AU2000269326A priority Critical patent/AU2000269326A1/en
Priority to PCT/US2000/023227 priority patent/WO2002015821A1/fr
Publication of WO2002015821A1 publication Critical patent/WO2002015821A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91508—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other the meander having a difference in amplitude along the band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91516—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other the meander having a change in frequency along the band
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
    • A61F2002/91541—Adjacent bands are arranged out of phase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91558—Adjacent bands being connected to each other connected peak to peak
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
    • A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
    • A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
    • A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
    • A61F2002/9155—Adjacent bands being connected to each other
    • A61F2002/91566—Adjacent bands being connected to each other connected trough to trough
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
    • A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers

Definitions

  • the present invention relates to stents and, most preferably, to stents which can be expanded, for example, by expanding an internally positioned balloon.
  • the heart functions as a pump to perfuse blood throughout the body through arteries.
  • the arteries of some patients are subject to stenosis, a localized partial blockage which narrows the passageway and interferes with normal blood flow. This condition is termed atherosclerotic coronary artery disease. It is a leading cause of morbidity in adults in
  • An angioplasty procedure generally includes inserting a deflated balloon, mounted on a
  • scaffolding device known as a stent, at the site of the stenosis.
  • the benefit of stenting may be as simple as preventing immediate elastic recoil and maintaining
  • Another challenge is to improve the medical effectiveness of stents.
  • jagged edges associated with stents can result in snagging in the arteries and can, therefore, cause complications during movement of the stent to the location of a stenosis to be
  • a tear in an artery wall resulting either from a snag or expansion mishap may require
  • radiopacity is also an issue with stents made of materials which are not radiopaque. It will be
  • Schepp-Pesch et al. U.S. Patent No. 5,354,309 disclose a spiral shaped sheet metal part which widens to a cylindrical jacket-shaped outer contour device at a transition temperature.
  • the device is formed from a memory alloy metal with
  • Burton discloses a self-expanding intraluminal prosthesis or stent which is tubular and has opposed ends and fenestrated walls.
  • Burton stent is taught to be prepared by molding, or alternatively, laser or water-jet cutting of a
  • a third example is Wolff (U.S. Patent No. 5,104,404), which discloses a number of stent
  • the Wolff hinges can be welded straight wire or coiled
  • Palmaz U.S. Patent Nos.
  • Palmaz stent is in fairly wide use in the U.S. and elsewhere. However, this stent is particularly
  • the stent should have the ability to "snake” around complex curves and tight curves encountered in the circulatory system, especially those associated with the coronary system which supplies critical blood flow to the heart.
  • the avoidance of any stent structure which tend to snag or catch on the interior of the various blood vessels is also desirable.
  • Wiktor U.S. Patent Nos. 4,969,458; 4,886,062; and 5, 133,732 also discloses articulating expandable stents. These stents generally coexist of one or more low memory metal wires which are wound in such a way to provide an articulating metal scaffolding structure which is balloon
  • the present invention provides advantages over the prior devices and solves other problems associated therewith.
  • the expandable stent of the present invention is expandable
  • the preferred stent including a
  • each of the modules having a plurality of individual expansion cells
  • Each of the preferred expansion cells including a continuous strand of a material, the continuous strand of material in each cell
  • Each expansion cell having an upper half and a lower half, the upper and lower halves being joined together and the lower half of each of the respective expansion cells being interconnected to the upper half of an adjacent expansion cell within that respective ring of
  • Each cell interconnection bridge having a center and each expansion cell having a radial length which is a radial distance consistent with an existing circumference of the respective ring as measured from the center of the cell interconnection bridge interconnected with the upper half of that expansion cell to the
  • the material being deformable such that the ring can be deformed from a first configuration
  • each ring has a first circumference and each expansion cell has a first radial length, to
  • each ring has a second circumference greater than the first
  • each expansion cell has a second radial length greater than the first radial
  • Each expansion cell preferably having a pair of sides which are mirror images of one another, each side being expandable when the ring of which the cell is a part is in the first configuration such that the second radial length can be at least twice as great as the first radial
  • each side will have an accordion shape which is expandable.
  • Preferred stents will have a plurality of intermodular connecting bridges; each intermodular
  • each pair of adjacent modules will be interconnected with one another by at least two intermodular connecting bridges.
  • the preferred stents of the present invention are expandable, typically, for example, by
  • the ring structures are joined end-to-end and feature an absence of potential tissue snagging structures.
  • the stents and ring structures of the preferred stents are characterized by relatively low surface area compared to the surface area of a simple cylinder of similar dimensions and connecting structures which allow the various ring structures to articulate with respect to one another.
  • the stents of the present invention are efficiently and easily
  • the stents of the present invention in certain embodiments which may be especially desirable during certain procedures, as they provide little
  • the expandable stent of the present invention includes a plurality of modules.
  • the modules have a plurality of individual cells radially interconnected to form a ring of
  • Each of the individual cells include a continuous strand of a material, the continuous strand of material in each cell being
  • the material employed is deformable, such that the ring can be deformed from a first configuration, wherein the ring has a first circumference, to a second configuration
  • the rings has an upper half and a lower half.
  • the upper and lower halves are joined together at
  • the plurality of modules includes at least first and second rings
  • module expansion cells The modules are oriented side by side such that the second ends of the first module are located proximate the first ends of the second module.
  • the respective expansion cells of each of the respective rings or modules are interconnected by a series of cell
  • each module is interconnected with adjacent modules by at least one intermodular connecting bridge which is interconnected with a cell interconnecting bridge in each of the respective adjacent rings or modules.
  • the modules can articulate relative to one another such that the modules of the expandable stent can pass through otherwise tortuous passageways with many "sharp" turns or twists.
  • each module is interconnected with adjacent modules by at least two
  • intermodular connecting bridges In preferred embodiments, these connecting bridges will connect with cell interconnection bridges which are separated in series by cell interconnection
  • module but may very well be so interconnected with the next module in series.
  • the intermodular connecting bridges will rotate radially around the cylindrical stent
  • the preferred expansion cells will have an upper half and a lower half which are mirror images of one another.
  • the material of the continuous strand of the preferred expandable stents of the present invention will be selected from amongst low memory metals such as tantalum,
  • the present invention is an expandable stent.
  • the stent again
  • the stent being expandable by enlarging an expandable balloon positioned within the stent.
  • each of the individual cells including a continuous strand of a material.
  • the continuous strand of material in each cell is interconnected with itself so as
  • Each cell has an upper half and a lower half, the upper half being a mirror image
  • FIG. 1 is a side view of a first embodiment of the present invention as temporarily mounted upon a balloon catheter (shown in hidden line) and shown in close association with a
  • FIG. 2 is a side view of the embodiment depicted in Figure 1 following inflation of the
  • balloon catheter (shown in Mdden line) inflated to deform and expand the expandable stent and
  • FIG. 3 is a schematic representation cross-sectional view of the stent and artery shown
  • FIG. 4 is a schematic representation cross-sectional view of the stent and artery shown
  • FIG. 5 is a partial plan view of an enlarged and flattened portion of the embodiment of Figure 1 as seen from the line 5-5 of Figure 3, assuming the circumferential surface is flattened, showing the unexpanded individual expansion cells of portion of respective rings or modules and the respective interconnecting or interconnection bridges;
  • FIG. 6A is a partial plan view of an enlarged and flattened portion of the expanded embodiment shown in Figure 2 as seen from the line 6-6 of Figure 4, assuming the circumferential surface is flattened, showing the expanded individual expansion cells of portions
  • FIG. 6B is a partial plan view of an enlarged and flattened portion of an expanded
  • FIG. 6C is a partial plan view of an enlarged and flattened portion and flattened of the expanded embodiment similar to that shown in Figure 2, assuming the circumferential surface is flattened, but showing only a single expanded expansion cell which is expanded more so than
  • FIG. 7 is a plan view of the expandable stent of the present invention similar to that
  • an expandable stent 30 of the present invention is
  • the stent 30 has a proximal end 32 and a distal end 34 and is depicted in Figure 1 as being temporarily fitted upon or generally coaxial with a balloon
  • catheter 40 (shown in hidden line), having a distal end 42, an expandable balloon 44 and a catheter shaft 46 .
  • the stent 30 is also shown closely associated within a portion of an artery 50 which is partially occluded by a stenosis 52.
  • the stent 30 can be expanded outward
  • Inflation of balloon 44 is accomplished by application of fluid pressure to its interior by the cardiologist, acting at the proximal end (not shown) of catheter 40 in a manner which is well known in the art.
  • stent 30 is also expanded outward radially. As the expansion continues, the stent
  • stenosis 52 is reformed to a more desirable shape and size, i.e. more nearly
  • Figures 1, 2 and 7 is especially flexible longitudinally. This flexibility makes it considerably
  • the balloon 44 can be any material shown in cross section in Figure 3. As schematically shown in Figure 4, the balloon 44 can be any material
  • the fluid pressure on the balloon 44 can be relieved and reduced.
  • the balloon 44 will contract
  • the retained expanded condition of the stent 30 serves to hold the stenosis 52 out of the channel of the artery 50 and restore patency to the artery 50. Because the stent 30 remains expanded but the balloon 44 contracts, withdrawal of the balloon 44 and the balloon catheter 40 is generally straightforward. Even after the balloon
  • catheter 40 is withdrawn from the patient, patency remains in the artery 50 and more appropriate circulation is possible for the tissues served by the treated artery 50.
  • the stent 30 remains as a support or scaffolding for the artery 50 and may also inhibit tissue prolapse and reformation of the stenosis 52.
  • radial thickness means the difference in the distance between
  • cells means the structure defining an
  • the cells under discussion in this disclosure have frames with a constant radial thickness and deform in response to radial force.
  • the frames may have curved sides, straight sides or combinations of curved and straight sides,
  • straight means appearing to take the shortest path between two points
  • apertures defined within each respective cell may increase or decrease in size as the shape of the
  • independent rings or “independent modules” means rings which can deform, for example by expanding on the order of, for example, but without limit, a 10% increase in radius, without an adjacent ring or module being expanded.
  • articulating means that two adjacent rings or modules can “articulate” so as to shift their respective axes from an orientation where the respective axes have a coincident orientation to an orientation where the respective axes have a non-coincident orientation thereby
  • the stent 30 is made up of a plurality of
  • modules or rings 60 which are closed loops and circumferentially extend about a central axis 45.
  • Each of the rings 60 have proximal ends 61 and distal ends 64. Each of the rings 60 has at least
  • An expansion cell 66 is a frame defining an
  • each cell 66 in the expandable stent 30 deforms when radial force is applied outwardly to each of the rings or modules 60 of the stent 30.
  • each ring 60 has a plurality of expansion cells 66 and, most preferably, each ring consists of a plurality of generally identical or nearly identical expansion cells lined up in
  • each expansion cell 66 is characterized by a greater longitudinal extent "L"
  • L of the cell 66 generally corresponds to the distance between the proximal and distal ends 61
  • each of the expansion cells 66 have an upper half or first portion 67a and a lower half or second portion 67b.
  • Each of the preferred cells 66 have a plurality of outwardly or inwardly extending segments 80a, 80b, 80c, 80d having the effect of allowing the expansion cell to expand circumferentially. These segments are the upper indirect segments 80a and the upper direct segments 80b of the upper half 67a of each expansion cell 66,
  • the indirect segments 80a, 80d pass through a series of oppositely extending curvilinear arcs, while the direct segments 80b, 80c are generally straight, hi alternate
  • expansion cell 66 have an accordion shape because of the accordion-like expansion joint 69,
  • each expansion cell 66 As used herein, therefore, an expansion cell which has an accordion
  • shape is an expansion cell which has a series of direct and/or indirect segments, preferably 4 in
  • each cell 66 which are joined together at alternating ends generally in a
  • expansion cells 66 to expand or stretch radially when the radially expanding balloon 44
  • Each expansion cell 66 is joined in series with other expansion cells in each ring or module 60 by a series of cell interconnection bridges 62, each of which has a center 63 midway between the respective expansion cells 66 to which the respective interconnection bridge 62 is
  • each ring or module 60 will be joined together by one or more intermodular connecting bridge 65 which will connect cell interconnection bridges 62 of the respective rings 60.
  • the stent 30 has a series of eight rings 60, each ring 60 being connected to each adjacent ring by two intermodular connecting bridges 65.
  • the number of intermodular connecting bridges 65 between each ring 60 can equal the number of cells 66 in each ring. This number will characteristically
  • each ring 60 has 5 cells 66,
  • each ring is joined to each adjacent ring by the intermodular connecting bridges 65.
  • the intermodular bridges 65 join non-consecutive opposing cell interconnection
  • modules are interconnected once, twice, three, four or more times, the respective
  • intermodular connecting bridges can vary and can take any possible
  • each successive pair of intermodular connecting bridges 65 joining each successive ring rotates around the stent 30 as the successive pair of intermodular bridges extend to the last ring at the distal end of the stent 30.
  • This extension has a generally helical orientation
  • the expansion cells 66 can expand as much as
  • radial length is the radial distance along the circumference of the stent 30 between the centers 63 of the respective cell interconnection bridges 62 on either side of an
  • expansion cells 66 As cells 66 expanded due to the radial force of an expanding balloon 44, the
  • the radial length can preferably increase from Rj to R 2 as it does when it increases
  • stents of the present invention may include as few as one module or ring and as many as 2, 3, 4, 5, 6, 7, 8, 9,
  • each ring 10 or even more rings if practical to provide greater length to the stent. Furthermore, each ring
  • module may include any practical number of cells, preferably from 2 to 10, more preferably
  • the present invention includes a method of making a stent.
  • preferred method includes providing a segment of cylindral walled material from which the stent
  • the stent is prepared by removal of material from the cylindrical wall
  • a computer aided laser cutting device is one option.
  • a computer aided water-jet cutting device is another option.
  • a removal technique is chemical etching of
  • an etching agent might be one of a number of acids which are well known in the art.
  • a hydrophobic coating such as a wax
  • etching is desired. If greater surface thickness is desired, wider areas need to be protected, if thinner, then narrower areas are protected. Alternatively, other means of selectively applying protective coatings, for example photographically based methods, which are well known in the etching arts, may be used. Finally, the partially protected cylinder is immersed in an acid bath. Etching occurs throughout the interior cylinder surface but only at selected portions of the exterior. When the etching has
  • the piece is removed from the acid.
  • the protective coating is
  • the coating is wax
  • the wax may be removed by heating or by a wax solvent which does not further affect the metal.
  • Chemical etching is a suitable production method for low
  • a preferred material from which expandable stents of this invention may be prepared is, without limit, stainless steel, particularly type 316 stainless steel, more preferably type 316 L or
  • Desirable features of the material selected are deformability and the ability to hold the
  • the stent 30 be made from radiopaque materials.
  • Stents made of stainless steel which have a thickness of 0.0005 inch are generally radiopaque
  • stents having lesser thicknesses such as stents made specifically for use in coronary arteries which often requires thicknesses less than 0.0005 inch (often for example about 0.003
  • radiopaque material such as 24 carat gold to a thickness of about 0.0002 inch.
  • other coatings including specific functional agents may also be
  • blood clotting e.g. Heparin and the like
  • reduction in the amount of intimal hyperplasia and resulting restenosis e.g. cytotoxic drugs, gene therapy agents and the like.
  • Methods to coat metal prostheses to make them radiopaque or to minimize the risks due to blood clotting are well known in the art and any of these methods and the devices resulting from the use of these methods are all envisioned within he scope of the present invention.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Physics & Mathematics (AREA)
  • Vascular Medicine (AREA)
  • Optics & Photonics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Prostheses (AREA)

Abstract

L'invention concerne un extenseur déployable (30) provisoirement emmanché sur un cathéter à ballonnet (40), possédant une extrémité distale (42), un ballonnet déployable (44) et une tige de cathéter (46). Dans un mode de réalisation, l'objet de l'invention possède cinq cellules (66) dans chaque anneau et deux ponts d'interconnexion (65) entre les ponts d'interconnexion opposés non consécutifs (62) de chaque anneau (60). Chaque paire suivante de ponts d'interconnexion intermodulaires (65) reliant chaque anneau suivant (60) pivote autour de l'extenseur (30) à mesure qu'une paire suivante de ponts d'interconnexion intermodulaires (65) se déploie en direction du dernier anneau à l'extrémité distale (42) de l'extenseur (30).
PCT/US2000/023227 2000-08-24 2000-08-24 Extenseur deployable comportant plusieurs modules de cellules de deploiement WO2002015821A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2000269326A AU2000269326A1 (en) 2000-08-24 2000-08-24 Expandable stent having a plurality of expansion cell modules
PCT/US2000/023227 WO2002015821A1 (fr) 2000-08-24 2000-08-24 Extenseur deployable comportant plusieurs modules de cellules de deploiement

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US2000/023227 WO2002015821A1 (fr) 2000-08-24 2000-08-24 Extenseur deployable comportant plusieurs modules de cellules de deploiement

Publications (1)

Publication Number Publication Date
WO2002015821A1 true WO2002015821A1 (fr) 2002-02-28

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005348813A (ja) * 2004-06-08 2005-12-22 Terumo Corp 生体内留置用ステントおよび生体器官拡張器具
JP2011115634A (ja) * 2011-03-16 2011-06-16 Terumo Corp 生体内留置用ステントおよび生体器官拡張器具
CN111093567A (zh) * 2017-09-12 2020-05-01 W.L.戈尔及同仁股份有限公司 具有可旋转支柱的医疗装置基底

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879381A (en) * 1996-03-10 1999-03-09 Terumo Kabushiki Kaisha Expandable stent for implanting in a body
US6013091A (en) * 1997-10-09 2000-01-11 Scimed Life Systems, Inc. Stent configurations

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5879381A (en) * 1996-03-10 1999-03-09 Terumo Kabushiki Kaisha Expandable stent for implanting in a body
US6013091A (en) * 1997-10-09 2000-01-11 Scimed Life Systems, Inc. Stent configurations

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2005348813A (ja) * 2004-06-08 2005-12-22 Terumo Corp 生体内留置用ステントおよび生体器官拡張器具
JP2011115634A (ja) * 2011-03-16 2011-06-16 Terumo Corp 生体内留置用ステントおよび生体器官拡張器具
CN111093567A (zh) * 2017-09-12 2020-05-01 W.L.戈尔及同仁股份有限公司 具有可旋转支柱的医疗装置基底
CN111093567B (zh) * 2017-09-12 2022-04-08 W.L.戈尔及同仁股份有限公司 具有可旋转支柱的医疗装置基底
US11559387B2 (en) 2017-09-12 2023-01-24 W. L Gore & Associates, Inc. Substrate with rotatable struts for medical device

Also Published As

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