WO2002009510A3 - Procedes de selection et de clonage - Google Patents

Procedes de selection et de clonage Download PDF

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Publication number
WO2002009510A3
WO2002009510A3 PCT/US2001/041561 US0141561W WO0209510A3 WO 2002009510 A3 WO2002009510 A3 WO 2002009510A3 US 0141561 W US0141561 W US 0141561W WO 0209510 A3 WO0209510 A3 WO 0209510A3
Authority
WO
WIPO (PCT)
Prior art keywords
cloning
animals
methods
cycle
selecting
Prior art date
Application number
PCT/US2001/041561
Other languages
English (en)
Other versions
WO2002009510A2 (fr
Inventor
Paul C Rebholtz
George L Holzer
Kenneth L White
Original Assignee
Xy Genetics Llc
Rebholtz Amy K
Holzer Kathleen
Kenneth L White
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Xy Genetics Llc, Rebholtz Amy K, Holzer Kathleen, Kenneth L White filed Critical Xy Genetics Llc
Priority to AU2001278204A priority Critical patent/AU2001278204A1/en
Priority to US10/343,578 priority patent/US20030172394A1/en
Publication of WO2002009510A2 publication Critical patent/WO2002009510A2/fr
Publication of WO2002009510A3 publication Critical patent/WO2002009510A3/fr
Priority to US11/627,297 priority patent/US20070136831A1/en

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/87Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
    • C12N15/873Techniques for producing new embryos, e.g. nuclear transfer, manipulation of totipotent cells or production of chimeric embryos
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027New or modified breeds of vertebrates
    • A01K67/0273Cloned vertebrates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/8509Vectors or expression systems specially adapted for eukaryotic hosts for animal cells for producing genetically modified animals, e.g. transgenic
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/05Animals comprising random inserted nucleic acids (transgenic)
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00Genetically modified animals
    • A01K2217/20Animal model comprising regulated expression system
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2227/00Animals characterised by species
    • A01K2227/10Mammal
    • A01K2227/101Bovine
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2267/00Animals characterised by purpose
    • A01K2267/02Animal zootechnically ameliorated

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Plant Pathology (AREA)
  • Veterinary Medicine (AREA)
  • Environmental Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Animal Husbandry (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Management, Administration, Business Operations System, And Electronic Commerce (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne des procédés de sélection et de clonage qui sont efficaces pour la multiplication sélective d'animaux spécifiques (par exemple, bétail). On peut ainsi étendre une population d'animaux, et l'intérêt particulier réside dans la duplication sur la base des caractéristiques mesurées après la mort de tel ou tel animal. Selon certaines variantes, on décrit des techniques utiles pour la sélection d'un bovin spécifique (par exemple, veau mâle châtré), au moins à partir d'une caractéristique de carcasse mesurable. L'invention concerne également des techniques de clonage spécifiques qui font intervenir des cycles répétitifs (par exemple, deux) de clonage, du type clonage par transfert nucléaire. Selon des variantes spécifiques, on décrit un système de clonage en deux étapes: le donneur nucléaire du premier cycle est une cellule fibroblastique adulte et le donneur nucléaire du second cycle est une cellule fibroblastique foetale recueillie sur un foetus à partir du premier cycle.
PCT/US2001/041561 2000-08-01 2001-08-01 Procedes de selection et de clonage WO2002009510A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU2001278204A AU2001278204A1 (en) 2000-08-01 2001-08-01 Methods of selecting and cloning animals
US10/343,578 US20030172394A1 (en) 2001-08-01 2001-08-01 Selection and cloning methods
US11/627,297 US20070136831A1 (en) 2000-08-01 2007-01-25 Selection and cloning methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22206800P 2000-08-01 2000-08-01
US60/222,068 2000-08-01

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US11/627,297 Division US20070136831A1 (en) 2000-08-01 2007-01-25 Selection and cloning methods

Publications (2)

Publication Number Publication Date
WO2002009510A2 WO2002009510A2 (fr) 2002-02-07
WO2002009510A3 true WO2002009510A3 (fr) 2002-08-15

Family

ID=22830676

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/041561 WO2002009510A2 (fr) 2000-08-01 2001-08-01 Procedes de selection et de clonage

Country Status (2)

Country Link
AU (1) AU2001278204A1 (fr)
WO (1) WO2002009510A2 (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9206478B2 (en) 2002-12-31 2015-12-08 Branhaven LLC Methods and systems for inferring bovine traits

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050177883A1 (en) * 2001-01-30 2005-08-11 Rebholtz Paul C. Systems of transferring embryos and managing recipients
DK3362578T3 (da) 2015-10-16 2020-11-02 Inguran Llc Fremgangsmåder til genomvurdering hos husdyr
US11377687B2 (en) 2015-10-16 2022-07-05 Inguran, Llc Methods of genomic evaluation in livestock

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998039416A1 (fr) * 1997-03-06 1998-09-11 Infigen, Inc. Methode de clonage d'animaux
WO1999023248A1 (fr) * 1997-10-30 1999-05-14 Commonwealth Scientific And Industrial Research Organisation Evaluation du metabolisme des graisses
EP0930009A1 (fr) * 1995-08-31 1999-07-21 Roslin Institute (Edinburgh) Population de cellules quiescentes pour transfert nucléaire
WO2000042174A1 (fr) * 1999-01-13 2000-07-20 Ppl Therapeutics (Scotland) Limited Procede de double transfert de noyau et resultats de ce transfert

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0930009A1 (fr) * 1995-08-31 1999-07-21 Roslin Institute (Edinburgh) Population de cellules quiescentes pour transfert nucléaire
WO1998039416A1 (fr) * 1997-03-06 1998-09-11 Infigen, Inc. Methode de clonage d'animaux
WO1999023248A1 (fr) * 1997-10-30 1999-05-14 Commonwealth Scientific And Industrial Research Organisation Evaluation du metabolisme des graisses
WO2000042174A1 (fr) * 1999-01-13 2000-07-20 Ppl Therapeutics (Scotland) Limited Procede de double transfert de noyau et resultats de ce transfert

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CIBELLI J B ET AL: "CLONED TRANSGENIC CALVES PRODUCED FROM NONQUIESCENT FETAL FIBROBLASTS", SCIENCE, AMERICAN ASSOCIATION FOR THE ADVANCEMENT OF SCIENCE,, US, vol. 280, 22 May 1998 (1998-05-22), pages 1256 - 1258, XP000786003, ISSN: 0036-8075 *
COLLEAU J -J ET AL: "Les biotechnologies de la reproduction chez les bovins et leurs applications réelles ou potentielles en selection", INRA PRODUCTIONS ANIMALES (PARIS), vol. 11, no. 1, January 1998 (1998-01-01), pages 41 - 56, XP001037237, ISSN: 0990-0632 *
SMITH C: "CLONING AND GENETIC IMPROVEMENT OF BEEF CATTLE", ANIMAL PRODUCTION, vol. 49, no. 1, 1989, pages 49 - 62, XP002187316, ISSN: 0003-3561 *
ZAKHARTCHENKO V ET AL: "Effects of serum starvation and re-cloning on the efficiency of nuclear transfer using bovine fetal fibroblasts.", JOURNAL OF REPRODUCTION AND FERTILITY, vol. 115, no. 2, March 1999 (1999-03-01), pages 325 - 331, XP001037005, ISSN: 0022-4251 *

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9206478B2 (en) 2002-12-31 2015-12-08 Branhaven LLC Methods and systems for inferring bovine traits

Also Published As

Publication number Publication date
AU2001278204A1 (en) 2002-02-13
WO2002009510A2 (fr) 2002-02-07

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