WO2002008283A3 - Lp120 polypeptides and therapeutic uses thereof - Google Patents

Lp120 polypeptides and therapeutic uses thereof Download PDF

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Publication number
WO2002008283A3
WO2002008283A3 PCT/US2001/016521 US0116521W WO0208283A3 WO 2002008283 A3 WO2002008283 A3 WO 2002008283A3 US 0116521 W US0116521 W US 0116521W WO 0208283 A3 WO0208283 A3 WO 0208283A3
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptides
therapeutic uses
relates
present
novel
Prior art date
Application number
PCT/US2001/016521
Other languages
French (fr)
Other versions
WO2002008283A2 (en
Inventor
Margret Barbara Basinski
Dong-Jing Fu
Bradley Jay Mills
Paul Robert Rosteck Jr
Patanjali Raghavac Sankhavaram
Original Assignee
Lilly Co Eli
Margret Barbara Basinski
Dong-Jing Fu
Bradley Jay Mills
Paul Robert Rosteck Jr
Patanjali Raghavac Sankhavaram
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli, Margret Barbara Basinski, Dong-Jing Fu, Bradley Jay Mills, Paul Robert Rosteck Jr, Patanjali Raghavac Sankhavaram filed Critical Lilly Co Eli
Priority to AU2001272919A priority Critical patent/AU2001272919A1/en
Publication of WO2002008283A2 publication Critical patent/WO2002008283A2/en
Publication of WO2002008283A3 publication Critical patent/WO2002008283A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention relates to the identification and isolation of novel DNA, therapeutic uses and the recombinant production of novel polypeptides cloned from a normalized human bone marrow cDNA library, designated herein as LP120 polypeptides. The present invention also relates to vectors, host cells, and antibodies directed to LP120 polypeptides.
PCT/US2001/016521 2000-07-20 2001-07-10 Lp120 polypeptides and therapeutic uses thereof WO2002008283A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001272919A AU2001272919A1 (en) 2000-07-20 2001-07-10 Lp120 polypeptides and therapeutic uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21958400P 2000-07-20 2000-07-20
US60/219,584 2000-07-20

Publications (2)

Publication Number Publication Date
WO2002008283A2 WO2002008283A2 (en) 2002-01-31
WO2002008283A3 true WO2002008283A3 (en) 2003-01-09

Family

ID=22819871

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016521 WO2002008283A2 (en) 2000-07-20 2001-07-10 Lp120 polypeptides and therapeutic uses thereof

Country Status (2)

Country Link
AU (1) AU2001272919A1 (en)
WO (1) WO2002008283A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004140A1 (en) * 1998-07-15 2000-01-27 Human Genome Sciences, Inc. 71 human secreted proteins

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000004140A1 (en) * 1998-07-15 2000-01-27 Human Genome Sciences, Inc. 71 human secreted proteins

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BAGGIOLINI M ET AL: "HUMAN CHEMOKINES: AN UPDATE", ANNUAL REVIEW OF IMMUNOLOGY, ANNUAL REVIEWS INC, US, vol. 15, 1997, pages 675 - 705, XP002055737, ISSN: 0732-0582 *
DATABASE EMBL [online] 14 April 2000 (2000-04-14), BIRREN B., ET AL.: "Homo sapiens chromosome 17 clone RP11-380J4 map 17, WORKING DRAFT SEQUENCE,38 unordered pieces.", XP002210376, Database accession no. AC044879 *
HOWARD O M Z ET AL: "Chemokines: progress toward identifying molecular targets for therapeutic agents", TRENDS IN BIOTECHNOLOGY, ELSEVIER PUBLICATIONS, CAMBRIDGE, GB, vol. 14, no. 2, 1 February 1996 (1996-02-01), pages 46 - 51, XP004035816, ISSN: 0167-7799 *
LOCATI M ET AL: "CHEMOKINES AND CHEMOKINE RECEPTORS: BIOLOGY AND CLINICAL RELEVANCE IN INFLAMMATION AND AIDS", ANNUAL REVIEW OF MEDICINE: SELECTED TOPICS IN THE CLINICAL SCIENCES, ANNUAL REVIEWS INC., PALO ALTO, CA, US, vol. 50, 1999, pages 425 - 440, XP000915015, ISSN: 0066-4219 *

Also Published As

Publication number Publication date
WO2002008283A2 (en) 2002-01-31
AU2001272919A1 (en) 2002-02-05

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