WO2002007516A3 - Uses for nad synthetase inhibitors - Google Patents
Uses for nad synthetase inhibitors Download PDFInfo
- Publication number
- WO2002007516A3 WO2002007516A3 PCT/US2001/022203 US0122203W WO0207516A3 WO 2002007516 A3 WO2002007516 A3 WO 2002007516A3 US 0122203 W US0122203 W US 0122203W WO 0207516 A3 WO0207516 A3 WO 0207516A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- nad synthetase
- synthetase inhibitors
- spore
- treating
- forming bacterium
- Prior art date
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/84—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms six-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,4
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/36—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids
- A01N37/38—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system
- A01N37/40—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a singly bound oxygen or sulfur atom attached to the same carbon skeleton, this oxygen or sulfur atom not being a member of a carboxylic group or of a thio analogue, or of a derivative thereof, e.g. hydroxy-carboxylic acids having at least one oxygen or sulfur atom attached to an aromatic ring system having at least one carboxylic group or a thio analogue, or a derivative thereof, and one oxygen or sulfur atom attached to the same aromatic ring system
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/44—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids containing at least one carboxylic group or a thio analogue, or a derivative thereof, and a nitrogen atom attached to the same carbon skeleton by a single or double bond, this nitrogen atom not being a member of a derivative or of a thio analogue of a carboxylic group, e.g. amino-carboxylic acids
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/02—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms
- A01N43/04—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom
- A01N43/06—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings
- A01N43/12—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one or more oxygen or sulfur atoms as the only ring hetero atoms with one hetero atom five-membered rings condensed with a carbocyclic ring
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
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- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/36—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings
- A01N43/38—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom five-membered rings condensed with carbocyclic rings
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/34—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom
- A01N43/40—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings
- A01N43/42—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with one nitrogen atom as the only ring hetero atom six-membered rings condensed with carbocyclic rings
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- A—HUMAN NECESSITIES
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- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/50—1,3-Diazoles; Hydrogenated 1,3-diazoles
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- A—HUMAN NECESSITIES
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- A01N61/00—Biocides, pest repellants or attractants, or plant growth regulators containing substances of unknown or undetermined composition, e.g. substances characterised only by the mode of action
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- A—HUMAN NECESSITIES
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- A23B4/00—General methods for preserving meat, sausages, fish or fish products
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- A23B5/00—Preservation of eggs or egg products
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- A23L3/00—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs
- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
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- A23L3/34—Preservation of foods or foodstuffs, in general, e.g. pasteurising, sterilising, specially adapted for foods or foodstuffs by treatment with chemicals
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- A23L3/3463—Organic compounds; Microorganisms; Enzymes
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- A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
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- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
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- A61L2/0005—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor for pharmaceuticals, biologicals or living parts
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- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Environmental Sciences (AREA)
- Plant Pathology (AREA)
- Pest Control & Pesticides (AREA)
- General Chemical & Material Sciences (AREA)
- Dentistry (AREA)
- Veterinary Medicine (AREA)
- Agronomy & Crop Science (AREA)
- Medicinal Chemistry (AREA)
- Polymers & Plastics (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Food Science & Technology (AREA)
- Microbiology (AREA)
- Organic Chemistry (AREA)
- Nutrition Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Animal Husbandry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Enzymes And Modification Thereof (AREA)
- Cultivation Of Plants (AREA)
Abstract
Priority Applications (10)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001280548A AU2001280548A1 (en) | 2000-07-14 | 2001-07-13 | Uses for NAD synthetase inhibitors |
BR0112514-1A BR0112514A (en) | 2000-07-14 | 2001-07-13 | Uses for nad synthetase inhibitors |
CA002415900A CA2415900A1 (en) | 2000-07-14 | 2001-07-13 | Uses for nad synthetase inhibitors |
JP2002513271A JP2004510704A (en) | 2000-07-14 | 2001-07-13 | Use of NAD synthetase inhibitors |
IL15357501A IL153575A0 (en) | 2000-07-14 | 2001-07-13 | Uses for nad synthetase inhibitors |
EP01958943A EP1301074A2 (en) | 2000-07-14 | 2001-07-13 | Uses for nad synthetase inhibitors |
PCT/US2002/005172 WO2003006628A2 (en) | 2001-07-13 | 2002-02-22 | Nad synthetase inhibitors and uses thereof |
JP2003512387A JP2005509594A (en) | 2001-07-13 | 2002-02-22 | NAD synthetase inhibitors and uses thereof |
US10/080,279 US6861448B2 (en) | 1998-01-14 | 2002-02-22 | NAD synthetase inhibitors and uses thereof |
EP02723209A EP1578898A2 (en) | 2001-07-13 | 2002-02-22 | Nad synthetase inhibitors and uses thereof |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US21840500P | 2000-07-14 | 2000-07-14 | |
US60/218,405 | 2000-07-14 |
Related Child Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/018029 Continuation-In-Part WO2001000197A2 (en) | 1998-01-14 | 2000-06-29 | Methods of treating fungal infections with inhibitors of nad synthetase enzyme |
US10/080,279 Continuation-In-Part US6861448B2 (en) | 1998-01-14 | 2002-02-22 | NAD synthetase inhibitors and uses thereof |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2002007516A2 WO2002007516A2 (en) | 2002-01-31 |
WO2002007516A3 true WO2002007516A3 (en) | 2002-06-27 |
Family
ID=22814976
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2001/022203 WO2002007516A2 (en) | 1998-01-14 | 2001-07-13 | Uses for nad synthetase inhibitors |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1301074A2 (en) |
JP (1) | JP2004510704A (en) |
AU (1) | AU2001280548A1 (en) |
BR (1) | BR0112514A (en) |
CA (1) | CA2415900A1 (en) |
IL (1) | IL153575A0 (en) |
WO (1) | WO2002007516A2 (en) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2005002337A1 (en) * | 2003-04-02 | 2005-01-13 | Virtual Drug Development, Inc. | Disinfectant compositions and methods |
ES2532138T3 (en) | 2008-10-23 | 2015-03-24 | Vertex Pharmaceuticals Incorporated | Modulators of cystic fibrosis transmembrane conductance regulator |
TWI465449B (en) | 2008-10-23 | 2014-12-21 | Vertex Pharma | Modulators of cystic fibrosis transmembrane conductance regulator |
TWI794742B (en) | 2020-02-18 | 2023-03-01 | 美商基利科學股份有限公司 | Antiviral compounds |
US12030903B2 (en) | 2020-02-18 | 2024-07-09 | Gilead Sciences, Inc. | Antiviral compounds |
TWI775313B (en) | 2020-02-18 | 2022-08-21 | 美商基利科學股份有限公司 | Antiviral compounds |
CN111386939A (en) * | 2020-03-16 | 2020-07-10 | 山西省农业科学院园艺研究所 | Cherry gummosis prevention and control method |
CA3216162A1 (en) | 2021-04-16 | 2022-10-20 | Gilead Sciences, Inc. | Methods of preparing carbanucleosides using amides |
Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
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EP0196530A2 (en) * | 1985-03-26 | 1986-10-08 | CTA Finanz AG | Agent and process for increasing growth, for optimizing fertility and for stimulating the immune system in humans and animals |
WO1999036422A1 (en) * | 1998-01-14 | 1999-07-22 | The Uab Research Foundation | Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial nad synthetase enzyme |
WO2000010996A1 (en) * | 1998-08-25 | 2000-03-02 | The Uab Research Foundation | Inhibitors of bacterial nad synthetase |
WO2001000197A2 (en) * | 1999-06-29 | 2001-01-04 | The Uab Research Foundation | Methods of treating fungal infections with inhibitors of nad synthetase enzyme |
-
2001
- 2001-07-13 IL IL15357501A patent/IL153575A0/en unknown
- 2001-07-13 WO PCT/US2001/022203 patent/WO2002007516A2/en not_active Application Discontinuation
- 2001-07-13 AU AU2001280548A patent/AU2001280548A1/en not_active Abandoned
- 2001-07-13 JP JP2002513271A patent/JP2004510704A/en active Pending
- 2001-07-13 BR BR0112514-1A patent/BR0112514A/en not_active Application Discontinuation
- 2001-07-13 CA CA002415900A patent/CA2415900A1/en not_active Abandoned
- 2001-07-13 EP EP01958943A patent/EP1301074A2/en not_active Withdrawn
Patent Citations (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0196530A2 (en) * | 1985-03-26 | 1986-10-08 | CTA Finanz AG | Agent and process for increasing growth, for optimizing fertility and for stimulating the immune system in humans and animals |
WO1999036422A1 (en) * | 1998-01-14 | 1999-07-22 | The Uab Research Foundation | Methods of synthesizing and screening inhibitors of bacterial nad synthetase enzyme, compounds thereof, and methods of treating bacterial and microbial infections with inhibitors of bacterial nad synthetase enzyme |
WO2000010996A1 (en) * | 1998-08-25 | 2000-03-02 | The Uab Research Foundation | Inhibitors of bacterial nad synthetase |
WO2001000197A2 (en) * | 1999-06-29 | 2001-01-04 | The Uab Research Foundation | Methods of treating fungal infections with inhibitors of nad synthetase enzyme |
Non-Patent Citations (5)
Title |
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BROUILLETTE W J ET AL: "SYNTHESIS OF INHIBITORS OF PROKARYOTIC NAD SYNTHETASE", AMERICAN CHEMICAL SOCIETY. ABSTRACTS OF PAPER. AT THE NATIONAL MEETING, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 218, no. PART 1, 22 August 1999 (1999-08-22), pages 295 - MEDI, XP000981304, ISSN: 0065-7727 * |
GARCIA J G ET AL: "SYNTHESIS OF POTENTIAL NAD SYNTHETASE INHIBITORS AS ANTIBACTERIAL AGENTS", AMERICAN CHEMICAL SOCIETY. ABSTRACTS OF PAPER. AT THE NATIONAL MEETING, AMERICAN CHEMICAL SOCIETY, WASHINGTON, DC, US, vol. 216, no. PART 2, 23 August 1998 (1998-08-23), pages 248 - MEDI, XP000979956, ISSN: 0065-7727 * |
H.A. TURNER ET AL.: "Production of slaughter steers from forages in the arid west", JOURNAL OF ANIMAL SCIENCE, vol. 44, no. 5, 1977, NEW YORK, NY, US, pages 901 - 907, XP001064470, ISSN: 0021-8812 * |
KATSUMI SHIBATA ET AL.: "Effect of dietary orotic acid on the levels of liver and blood NAD in rats", JOURNAL OF NUTRITIONAL SCIENCE AND VITAMINOLOGY., vol. 31, no. 3, 1985, XX, XX, pages 265 - 278, XP001064472 * |
KATSUMI SHIBATA ET AL.: "Effect of dietary paraquat on the enzyme activities involved in tryptophan-niacin metabolism in rats", AGRICULTURAL AND BIOLOGICAL CHEMISTRY., vol. 52, no. 7, 1988, JAPAN SOC. FOR BIOSCIENCE, BIOTECHNOLOGY AND AGROCHEM. TOKYO., JP, pages 1857 - 1858, XP002193914, ISSN: 0002-1369 * |
Also Published As
Publication number | Publication date |
---|---|
BR0112514A (en) | 2003-07-01 |
WO2002007516A2 (en) | 2002-01-31 |
IL153575A0 (en) | 2003-07-06 |
AU2001280548A1 (en) | 2002-02-05 |
EP1301074A2 (en) | 2003-04-16 |
JP2004510704A (en) | 2004-04-08 |
CA2415900A1 (en) | 2002-01-31 |
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