WO2002005827A3 - Use of natural products in cancer treatment - Google Patents

Use of natural products in cancer treatment Download PDF

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Publication number
WO2002005827A3
WO2002005827A3 PCT/GB2001/003150 GB0103150W WO0205827A3 WO 2002005827 A3 WO2002005827 A3 WO 2002005827A3 GB 0103150 W GB0103150 W GB 0103150W WO 0205827 A3 WO0205827 A3 WO 0205827A3
Authority
WO
WIPO (PCT)
Prior art keywords
cancer treatment
natural products
cancer
isoflavones
micronutrients
Prior art date
Application number
PCT/GB2001/003150
Other languages
French (fr)
Other versions
WO2002005827A2 (en
Inventor
Paul Rodney Clayton
Harcharan Rooperai
David Dexter
Original Assignee
Forum Bioscience
Paul Rodney Clayton
Harcharan Rooperai
David Dexter
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0017620A external-priority patent/GB0017620D0/en
Priority claimed from GB0023574A external-priority patent/GB0023574D0/en
Priority claimed from GB0026600A external-priority patent/GB0026600D0/en
Application filed by Forum Bioscience, Paul Rodney Clayton, Harcharan Rooperai, David Dexter filed Critical Forum Bioscience
Priority to AU2001276462A priority Critical patent/AU2001276462A1/en
Publication of WO2002005827A2 publication Critical patent/WO2002005827A2/en
Publication of WO2002005827A3 publication Critical patent/WO2002005827A3/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L33/00Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
    • A23L33/10Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
    • A23L33/105Plant extracts, their artificial duplicates or their derivatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/168Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23VINDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
    • A23V2002/00Food compositions, function of food ingredients or processes for food or foodstuffs

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Nutrition Science (AREA)
  • Food Science & Technology (AREA)
  • Polymers & Plastics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

A programme of micronutrients designed specifically to modify all the known steps in the cancer sequence comprises administering an effective amount of one or more flavonoids, one or more lectins, one or more isoflavones, one or more carotenoids, betaine and selenium to a mammal suffering from cancer as a combination therapy in which the components are administered together, concurrently or sequentially.
PCT/GB2001/003150 2000-07-18 2001-07-18 Use of natural products in cancer treatment WO2002005827A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001276462A AU2001276462A1 (en) 2000-07-18 2001-07-18 Use of natural products in cancer treatment

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB0017620.6 2000-07-18
GB0017620A GB0017620D0 (en) 2000-07-18 2000-07-18 Flavonoids in cancer treatment
GB0023574.7 2000-09-26
GB0023574A GB0023574D0 (en) 2000-09-26 2000-09-26 Use of natural products in cancer treatment
GB0026600.7 2000-10-31
GB0026600A GB0026600D0 (en) 2000-10-31 2000-10-31 Use of natural products in cancer treatment

Publications (2)

Publication Number Publication Date
WO2002005827A2 WO2002005827A2 (en) 2002-01-24
WO2002005827A3 true WO2002005827A3 (en) 2002-07-18

Family

ID=27255810

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/003150 WO2002005827A2 (en) 2000-07-18 2001-07-18 Use of natural products in cancer treatment

Country Status (2)

Country Link
AU (1) AU2001276462A1 (en)
WO (1) WO2002005827A2 (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2836046B1 (en) * 2002-02-15 2006-09-15 Marie Jose Touche NOVEL THERAPEUTIC APPLICATION OF COMPOUND A: BUTOFORM OR SCUROFORM ASSOCIATED WITH PRODUCT B: EUGENOL AND PRODUCT C: ZINC OXIDE, ADDED TO LYCOPENE
WO2003068202A1 (en) * 2002-02-15 2003-08-21 Dsm Ip Assets B.V. Compositions comprising lycopene for the treatment and prevention of angiogenesis associated pathologies
DE10310196A1 (en) * 2003-03-06 2004-09-23 Rina-Netzwerk Rna Technologien Gmbh Use a tricyclic antidepressant to promote endocytosis
US9597311B2 (en) * 2005-09-27 2017-03-21 Robert Benson Aylor Suppression and prevention of tumors
EP2260856A1 (en) 2009-05-12 2010-12-15 URSAPHARM Arzneimittel GmbH Immune stimulating composition comprising an extract of aronia sp. in combination with selenium and/or zinc
US9572783B1 (en) 2015-10-08 2017-02-21 Chuen Wei Lu Use of xanthophylls for the treatment of cancers
EP3153160B1 (en) * 2015-10-08 2021-08-11 Chuen Wei Lu Use of xanthophylls for the treatment of cancers

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4111208A1 (en) * 1991-04-06 1992-10-08 Inge Witte Plant extract for treating cancer - comprises Thuja soln., elder, beetroot, wheat germ oil, lacto- and soya protein and wild yeast
EP0627173A1 (en) * 1993-05-31 1994-12-07 GIULIANI S.p.A. Preparation for dietetic use or as a food supplement, with targeted release in the colon
WO1995021542A1 (en) * 1994-02-08 1995-08-17 Vioryl Chemical And Agricultural Industry, Research S.A. A natural and healthy juice
WO1999007400A1 (en) * 1997-08-06 1999-02-18 Melaleuca, Incorporated Dietary supplements containing natural ingredients
US6103756A (en) * 1999-08-11 2000-08-15 Vitacost Inc. Ocular orally ingested composition for prevention and treatment of individuals
WO2001019383A1 (en) * 1999-09-17 2001-03-22 Alcon, Inc. Stable carotene-xanthophyll beadlet compositions and methods of use
WO2001085183A2 (en) * 2000-05-08 2001-11-15 N.V. Nutricia Preparation for the prevention and treatment of ocular disorders

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4111208A1 (en) * 1991-04-06 1992-10-08 Inge Witte Plant extract for treating cancer - comprises Thuja soln., elder, beetroot, wheat germ oil, lacto- and soya protein and wild yeast
EP0627173A1 (en) * 1993-05-31 1994-12-07 GIULIANI S.p.A. Preparation for dietetic use or as a food supplement, with targeted release in the colon
WO1995021542A1 (en) * 1994-02-08 1995-08-17 Vioryl Chemical And Agricultural Industry, Research S.A. A natural and healthy juice
WO1999007400A1 (en) * 1997-08-06 1999-02-18 Melaleuca, Incorporated Dietary supplements containing natural ingredients
US6103756A (en) * 1999-08-11 2000-08-15 Vitacost Inc. Ocular orally ingested composition for prevention and treatment of individuals
WO2001019383A1 (en) * 1999-09-17 2001-03-22 Alcon, Inc. Stable carotene-xanthophyll beadlet compositions and methods of use
WO2001085183A2 (en) * 2000-05-08 2001-11-15 N.V. Nutricia Preparation for the prevention and treatment of ocular disorders

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CARROLL K K ET AL: "ANTICANCER PROPERTIES OF FLAVONOIDS, WITH EMPHASIS ON CITRUS FLAVONOIDS", ANTIOXIDANTS IN HEALTH AND DISEASE, MARCEL DEKKER, NEW YORK, NY,, US, vol. 7, 1998, pages 437 - 446, XP000960909, ISSN: 1521-4486 *
COMBS G F JR ET AL: "Reduction of cancer mortality and incidence by selenium supplementation", MEDIZINISCHE KLINIK, XX, XX, vol. 92, no. SUPPL 3, 1997, pages 42 - 45, XP002123911 *
FRANKEL E N: "NUTRITIONAL BENEFITS OF FLAVONOIDS", FOOD FACTORS FOR CANCER PREVENTION, XX, XX, 1997, pages 613 - 616, XP000886654 *
MOULY PIERRE P ET AL: "Determination of the geographical origin of valencia orange juice using carotenoid liquid chromatographic profiles.", JOURNAL OF CHROMATOGRAPHY A, vol. 844, no. 1-2, 4 June 1999 (1999-06-04), pages 149 - 159, XP004170302, ISSN: 0021-9673 *
SO F V ET AL: "INHIBITION OF HUMAN BREAST CANCER CELL PROLIFERATION AND DELAY OF MAMMARY TUMORIGENESIS BY FLAVONOIDS AND CITRUS JUICES", NUTRITION AND CANCER, LONDON, GB, vol. 26, no. 2, 1996, pages 167 - 181, XP000938970, ISSN: 0163-5581 *

Also Published As

Publication number Publication date
AU2001276462A1 (en) 2002-01-30
WO2002005827A2 (en) 2002-01-24

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