WO2002002777A3 - Gpsa gene from corynebaxteria and use thereof in synthesis of l-amino acids - Google Patents

Gpsa gene from corynebaxteria and use thereof in synthesis of l-amino acids Download PDF

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Publication number
WO2002002777A3
WO2002002777A3 PCT/EP2001/005493 EP0105493W WO0202777A3 WO 2002002777 A3 WO2002002777 A3 WO 2002002777A3 EP 0105493 W EP0105493 W EP 0105493W WO 0202777 A3 WO0202777 A3 WO 0202777A3
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WO
WIPO (PCT)
Prior art keywords
amino acids
corynebaxteria
synthesis
gpsa gene
gpsa
Prior art date
Application number
PCT/EP2001/005493
Other languages
French (fr)
Other versions
WO2002002777A2 (en
Inventor
Madhavan Nampoothiri
Brigitte Bathe
Lothar Eggeling
Hermann Sahm
Original Assignee
Degussa
Forschungszentrum Juelich Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE10032174A external-priority patent/DE10032174A1/en
Application filed by Degussa, Forschungszentrum Juelich Gmbh filed Critical Degussa
Priority to EP01962683A priority Critical patent/EP1297149A2/en
Priority to AU2001283819A priority patent/AU2001283819A1/en
Publication of WO2002002777A2 publication Critical patent/WO2002002777A2/en
Publication of WO2002002777A3 publication Critical patent/WO2002002777A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

This invention relates to a coryneform bacterium, the gpsA gene of which is enhanced, to an isolated polynucleotide which encodes glycerol-3-phosphate dehydrogenase from coryneform bacteria, and also to a process for the fermentative production of L-amino acids with enhancement of the gpsA gene in the bacteria.
PCT/EP2001/005493 2000-07-01 2001-05-15 Gpsa gene from corynebaxteria and use thereof in synthesis of l-amino acids WO2002002777A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01962683A EP1297149A2 (en) 2000-07-01 2001-05-15 Gpsa gene from corynebacteria and use thereof in synthesis of l-amino acids
AU2001283819A AU2001283819A1 (en) 2000-07-01 2001-05-15 New nucleotide sequences which encode the gpsa gene

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE10032174.7 2000-07-01
DE10032174A DE10032174A1 (en) 2000-07-01 2000-07-01 Novel coryneform bacterium in which the gpsA gene encoding glycerol-3-phosphate dehydrogenase is enhanced, useful for fermentative production of L-amino acids such as L-lysine and L-glutamate
US09/796,431 US20020034794A1 (en) 2000-07-01 2001-03-02 Nucleotide sequences which encode the gpsA gene
US09/796,431 2001-03-02

Publications (2)

Publication Number Publication Date
WO2002002777A2 WO2002002777A2 (en) 2002-01-10
WO2002002777A3 true WO2002002777A3 (en) 2002-05-16

Family

ID=26006260

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/005493 WO2002002777A2 (en) 2000-07-01 2001-05-15 Gpsa gene from corynebaxteria and use thereof in synthesis of l-amino acids

Country Status (3)

Country Link
EP (1) EP1297149A2 (en)
AU (1) AU2001283819A1 (en)
WO (1) WO2002002777A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE102005047596A1 (en) 2005-10-05 2007-04-12 Degussa Ag Process for the fermentative production of L-amino acids using coryneform bacteria

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001000844A2 (en) * 1999-06-25 2001-01-04 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in carbon metabolism and energy production

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001000844A2 (en) * 1999-06-25 2001-01-04 Basf Aktiengesellschaft Corynebacterium glutamicum genes encoding proteins involved in carbon metabolism and energy production

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HÉCTOR RICARDO MORBIDONI ET AL.: "Synthesis of sn-Glycerol 3 -Phosphate, a key precursor of membrane lipids, in Bacillus subtilis", JOURNAL OF BACTERIOLOFY, vol. 177, no. 20, October 1995 (1995-10-01), pages 5899 - 5905, XP002186763 *

Also Published As

Publication number Publication date
EP1297149A2 (en) 2003-04-02
AU2001283819A1 (en) 2002-01-14
WO2002002777A2 (en) 2002-01-10

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