WO2002002001A8 - Epithelial diagnostic aid - Google Patents

Epithelial diagnostic aid

Info

Publication number
WO2002002001A8
WO2002002001A8 PCT/GB2001/003011 GB0103011W WO0202001A8 WO 2002002001 A8 WO2002002001 A8 WO 2002002001A8 GB 0103011 W GB0103011 W GB 0103011W WO 0202001 A8 WO0202001 A8 WO 0202001A8
Authority
WO
WIPO (PCT)
Prior art keywords
intensity
epithelial
lesion
variation
relates
Prior art date
Application number
PCT/GB2001/003011
Other languages
French (fr)
Other versions
WO2002002001A3 (en
WO2002002001A2 (en
Inventor
Michael Roger Cane
Symon D Oyly Cotton
Matthew Alexander Schumann
Michael Andrew Beadman
Thomas Scott Carter
Philip James Churchill White
Rebeca Lapping
Jeremy Carey
Original Assignee
Astron Clinica Ltd
Michael Roger Cane
Symon D Oyly Cotton
Matthew Alexander Schumann
Michael Andrew Beadman
Thomas Scott Carter
Philip James Churchill White
Rebeca Lapping
Jeremy Carey
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0016392A external-priority patent/GB2364376A/en
Priority claimed from GB0016690A external-priority patent/GB2364567A/en
Priority claimed from GB0112501A external-priority patent/GB0112501D0/en
Application filed by Astron Clinica Ltd, Michael Roger Cane, Symon D Oyly Cotton, Matthew Alexander Schumann, Michael Andrew Beadman, Thomas Scott Carter, Philip James Churchill White, Rebeca Lapping, Jeremy Carey filed Critical Astron Clinica Ltd
Priority to US10/332,222 priority Critical patent/US20040092802A1/en
Priority to JP2002506633A priority patent/JP2004501712A/en
Priority to EP01949639A priority patent/EP1296593A2/en
Priority to AU2001270762A priority patent/AU2001270762A1/en
Publication of WO2002002001A2 publication Critical patent/WO2002002001A2/en
Publication of WO2002002001A8 publication Critical patent/WO2002002001A8/en
Publication of WO2002002001A3 publication Critical patent/WO2002002001A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/444—Evaluating skin marks, e.g. mole, nevi, tumour, scar
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/443—Evaluating skin constituents, e.g. elastin, melanin, water
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/44—Detecting, measuring or recording for evaluating the integumentary system, e.g. skin, hair or nails
    • A61B5/441—Skin evaluation, e.g. for skin disorder diagnosis
    • A61B5/445—Evaluating skin irritation or skin trauma, e.g. rash, eczema, wound, bed sore

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Biophysics (AREA)
  • Pathology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Veterinary Medicine (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Dermatology (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Measuring And Recording Apparatus For Diagnosis (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)

Abstract

The present invention relates to devices and methodology for determining the variation in concentration of chromophores within an epithelial tissue. The devices comprise a means of illuminate the skin at one or more points and at wavelengths corresponding to specific chromophores. The device further comprises a detection means configured to detect the intensity of light remitted from the epithelial surface, a processing means configured to interpret image data sets obtained by the detection means and an output display to display the results or significance of the results. The invention further extends to a method of interpreting the distribution of chromphores within a lesion of an epithelial tissue. The method comprising the steps of illuminating an epithelial surface, determining the intensity of remitted light, analysing said intensity data to determine variation in the intensity across the lesion and providing an output corresponding to the extend of variation across the lesion. One aspec of the invention relates to a hand-held design of the device for implementing the aforementioned method. Another aspect of the invention relates to the design of the patient-contacting part of the device to prevent of contaminants and to improve the diagnostic effectiveness of the device.
PCT/GB2001/003011 2000-07-05 2001-07-04 Epithelial diagnostic aid WO2002002001A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
US10/332,222 US20040092802A1 (en) 2000-07-07 2001-07-04 Epithelial diagnostic aid
JP2002506633A JP2004501712A (en) 2000-07-05 2001-07-04 Epidermis diagnosis support device
EP01949639A EP1296593A2 (en) 2000-07-05 2001-07-04 Ephitelial diagnostic aid
AU2001270762A AU2001270762A1 (en) 2000-07-05 2001-07-04 Epithelial diagnostic aid

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB0016392.3 2000-07-05
GB0016392A GB2364376A (en) 2000-07-05 2000-07-05 Skin illumination and examination apparatus
GB0016690.0 2000-07-07
GB0016690A GB2364567A (en) 2000-07-07 2000-07-07 Determining distribution of chromophores in skin or other epithelial tissue
GB0112501A GB0112501D0 (en) 2001-05-23 2001-05-23 Portable device for assessing the presence of melanin within the dermis of skin
GB0112501.2 2001-05-23

Publications (3)

Publication Number Publication Date
WO2002002001A2 WO2002002001A2 (en) 2002-01-10
WO2002002001A8 true WO2002002001A8 (en) 2002-07-04
WO2002002001A3 WO2002002001A3 (en) 2002-10-24

Family

ID=27255793

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/003011 WO2002002001A2 (en) 2000-07-05 2001-07-04 Epithelial diagnostic aid

Country Status (4)

Country Link
EP (1) EP1296593A2 (en)
JP (1) JP2004501712A (en)
AU (1) AU2001270762A1 (en)
WO (1) WO2002002001A2 (en)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0217570D0 (en) 2002-07-30 2002-09-11 Univ Birmingham Method and apparatus for quantifying material or object properties
AU2003255745B2 (en) * 2002-07-30 2007-03-22 Medx Health Corporation Method and apparatus for quantifying tissue histology
US9750449B2 (en) 2003-12-12 2017-09-05 Johnson & Johnson Consumer Inc. Method of assessing skin
US7274453B2 (en) * 2004-10-14 2007-09-25 The Procter & Gamble Company Methods and apparatus for calibrating an electromagnetic measurement device
JP2006218291A (en) * 2005-01-13 2006-08-24 Nidec Copal Corp Skin observation apparatus
US20060244961A1 (en) * 2005-04-29 2006-11-02 Cole Curtis A Topical composition detection
GB2429385C (en) * 2005-09-23 2008-04-24 Astron Clinica Ltd Image processing method and apparatus.
GB2443389A (en) * 2006-11-03 2008-05-07 Astron Clinica Ltd Method and apparatus for obtaining a measurement of sun damage
EP2040061A1 (en) * 2007-09-24 2009-03-25 Koninklijke Philips Electronics N.V. An apparatus and method for observing the surface of a sample
KR101124641B1 (en) 2008-10-02 2012-03-22 현석산 Apparatus for analyzing cerebral artery
JP5427388B2 (en) * 2008-10-07 2014-02-26 ショットモリテックス株式会社 Skin observation device
EP2422185A4 (en) * 2009-04-20 2013-02-13 Univ Missouri Photoacoustic detection of analytes in solid tissue and detection system
JP2013132542A (en) * 2011-12-27 2013-07-08 Sharp Corp Measuring instrument

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3827457A1 (en) * 1987-11-27 1989-06-08 Bernhard Dr Ludwig Method and device for the relative quantitative determination of chromophores in surface layers
DK60790A (en) * 1990-03-08 1991-09-09 Henrik Bernhard Lemming METHOD OF REFLECTION MEASUREMENT
DE4427101A1 (en) * 1994-07-30 1996-02-01 Boehringer Mannheim Gmbh Apparatus and method for the optical characterization of the structure and composition of a scattering sample
US5788639A (en) * 1995-07-13 1998-08-04 Lucid Technologies, Inc. Confocal imaging through thick dermal tissue
GB9624003D0 (en) * 1996-11-19 1997-01-08 Univ Birmingham Method and apparatus for measurement of skin histology

Also Published As

Publication number Publication date
AU2001270762A1 (en) 2002-01-14
WO2002002001A3 (en) 2002-10-24
JP2004501712A (en) 2004-01-22
EP1296593A2 (en) 2003-04-02
WO2002002001A2 (en) 2002-01-10

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