WO2002000701A3 - Regulation of human gonadotropin releasing hormone receptor-like g protein-coupled receptor - Google Patents

Regulation of human gonadotropin releasing hormone receptor-like g protein-coupled receptor Download PDF

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Publication number
WO2002000701A3
WO2002000701A3 PCT/EP2001/007212 EP0107212W WO0200701A3 WO 2002000701 A3 WO2002000701 A3 WO 2002000701A3 EP 0107212 W EP0107212 W EP 0107212W WO 0200701 A3 WO0200701 A3 WO 0200701A3
Authority
WO
WIPO (PCT)
Prior art keywords
releasing hormone
gonadotropin releasing
hormone receptor
receptor
protein
Prior art date
Application number
PCT/EP2001/007212
Other languages
French (fr)
Other versions
WO2002000701A2 (en
Inventor
Shyam Ramakrishnan
Original Assignee
Bayer Ag
Shyam Ramakrishnan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Shyam Ramakrishnan filed Critical Bayer Ag
Priority to AU2001281882A priority Critical patent/AU2001281882A1/en
Publication of WO2002000701A2 publication Critical patent/WO2002000701A2/en
Publication of WO2002000701A3 publication Critical patent/WO2002000701A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/72—Receptors; Cell surface antigens; Cell surface determinants for hormones
    • C07K14/723—G protein coupled receptor, e.g. TSHR-thyrotropin-receptor, LH/hCG receptor, FSH receptor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Reagents which regulate human gonadotropin releasing hormone receptor G protein-coupled receptor (gonadotropin releasing hormone receptor-like GPCR) and reagents which bind to human gonadotropin releasing hormone receptor-like GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, urinary incontince, benign prostate hyperplasia, obesity and diseases related to obesity, cancer, diabetes, osteoporosis, anxiety, depression, hypertension, migraine, compulsive disorders, schizophrenia, autism, neurodegenerative disorders, such as Alzheimer's disease, Parkinsonism, and Huntington's chorea, and cancer chemotherapy-induced vomiting.
PCT/EP2001/007212 2000-06-26 2001-06-25 Regulation of human gonadotropin releasing hormone receptor-like g protein-coupled receptor WO2002000701A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001281882A AU2001281882A1 (en) 2000-06-26 2001-06-25 Regulation of human gonadotropin releasing hormone receptor-like g protein-coupled receptor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US21424900P 2000-06-26 2000-06-26
US60/214,249 2000-06-26

Publications (2)

Publication Number Publication Date
WO2002000701A2 WO2002000701A2 (en) 2002-01-03
WO2002000701A3 true WO2002000701A3 (en) 2002-06-13

Family

ID=22798355

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/007212 WO2002000701A2 (en) 2000-06-26 2001-06-25 Regulation of human gonadotropin releasing hormone receptor-like g protein-coupled receptor

Country Status (2)

Country Link
AU (1) AU2001281882A1 (en)
WO (1) WO2002000701A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2259418T3 (en) 2002-07-22 2006-10-01 Ardana Bioscience Limited METHOD OF SYSTEMATIC DETECTION AND PHARMACO ANTITUMOR CANDIDATE.

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997047743A1 (en) * 1996-06-13 1997-12-18 Zymogenetics, Inc. Human type ii gonadotropin-releasing hormone receptor
WO2001078796A1 (en) * 2000-04-15 2001-10-25 Medical Res Council Type ii gonadotropin-releasing hormone receptor and polynucleotides encoding therefor
WO2001083553A2 (en) * 2000-05-03 2001-11-08 Pharmacia & Upjohn Company G protein-coupled receptors

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997047743A1 (en) * 1996-06-13 1997-12-18 Zymogenetics, Inc. Human type ii gonadotropin-releasing hormone receptor
WO2001078796A1 (en) * 2000-04-15 2001-10-25 Medical Res Council Type ii gonadotropin-releasing hormone receptor and polynucleotides encoding therefor
WO2001083553A2 (en) * 2000-05-03 2001-11-08 Pharmacia & Upjohn Company G protein-coupled receptors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 8 May 1998 (1998-05-08), NCI-CGAP: "on56c03.s1 Soares_NFL_T_GBC_S1 Homo sapiens cDNA clone IMAGE:1560676 3' similar to SW:GRHR_PIG P49922 GONADOTROPIN-RELEASING HORMONE RECEPTOR ;, mRNA sequence.", XP002193641 *

Also Published As

Publication number Publication date
WO2002000701A2 (en) 2002-01-03
AU2001281882A1 (en) 2002-01-08

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