WO2001090700A3 - Novel method and apparatus for flow monitoring in micro-fluidic devices - Google Patents

Novel method and apparatus for flow monitoring in micro-fluidic devices Download PDF

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Publication number
WO2001090700A3
WO2001090700A3 PCT/US2001/016765 US0116765W WO0190700A3 WO 2001090700 A3 WO2001090700 A3 WO 2001090700A3 US 0116765 W US0116765 W US 0116765W WO 0190700 A3 WO0190700 A3 WO 0190700A3
Authority
WO
WIPO (PCT)
Prior art keywords
micro
novel method
flow monitoring
fluidic devices
fluid
Prior art date
Application number
PCT/US2001/016765
Other languages
French (fr)
Other versions
WO2001090700A2 (en
Inventor
Mark A Hayes
St Joseph C Claire
Original Assignee
Mark A Hayes
St Joseph C Claire
Univ Arizona
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mark A Hayes, St Joseph C Claire, Univ Arizona filed Critical Mark A Hayes
Priority to AU2001274919A priority Critical patent/AU2001274919A1/en
Priority to US10/296,431 priority patent/US20040008335A1/en
Publication of WO2001090700A2 publication Critical patent/WO2001090700A2/en
Publication of WO2001090700A3 publication Critical patent/WO2001090700A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F1/00—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow
    • G01F1/68—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow by using thermal effects
    • G01F1/684—Structural arrangements; Mounting of elements, e.g. in relation to fluid flow
    • G01F1/688—Structural arrangements; Mounting of elements, e.g. in relation to fluid flow using a particular type of heating, cooling or sensing element
    • G01F1/6884—Structural arrangements; Mounting of elements, e.g. in relation to fluid flow using a particular type of heating, cooling or sensing element making use of temperature dependence of optical properties
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F1/00—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow
    • G01F1/704—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow using marked regions or existing inhomogeneities within the fluid stream, e.g. statistically occurring variations in a fluid parameter
    • G01F1/708—Measuring the time taken to traverse a fixed distance
    • G01F1/7086—Measuring the time taken to traverse a fixed distance using optical detecting arrangements
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01F—MEASURING VOLUME, VOLUME FLOW, MASS FLOW OR LIQUID LEVEL; METERING BY VOLUME
    • G01F1/00—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow
    • G01F1/704—Measuring the volume flow or mass flow of fluid or fluent solid material wherein the fluid passes through a meter in a continuous flow using marked regions or existing inhomogeneities within the fluid stream, e.g. statistically occurring variations in a fluid parameter
    • G01F1/708—Measuring the time taken to traverse a fixed distance
    • G01F1/7084—Measuring the time taken to traverse a fixed distance using thermal detecting arrangements

Landscapes

  • Physics & Mathematics (AREA)
  • Fluid Mechanics (AREA)
  • General Physics & Mathematics (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Measuring Volume Flow (AREA)

Abstract

The present invention relates to a process for monitoring the flow rate of a fluid stream which comprises heating the stream with a heating member for a time sufficient to induce a change in the refractive index of the fluid; detecting the change in the refractive index of the fluid at a location remote from the heating member; and calculating the flow rate of the fluid from the change in the refractive index.
PCT/US2001/016765 2000-05-23 2001-05-23 Novel method and apparatus for flow monitoring in micro-fluidic devices WO2001090700A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU2001274919A AU2001274919A1 (en) 2000-05-23 2001-05-23 Novel method and apparatus for flow monitoring in micro-fluidic devices
US10/296,431 US20040008335A1 (en) 2001-05-23 2001-05-23 Novel method and apparatus for flow monitoring in mirco-fluidic devices

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20647900P 2000-05-23 2000-05-23
US60/206,479 2000-05-23

Publications (2)

Publication Number Publication Date
WO2001090700A2 WO2001090700A2 (en) 2001-11-29
WO2001090700A3 true WO2001090700A3 (en) 2002-04-25

Family

ID=22766581

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/016765 WO2001090700A2 (en) 2000-05-23 2001-05-23 Novel method and apparatus for flow monitoring in micro-fluidic devices

Country Status (2)

Country Link
AU (1) AU2001274919A1 (en)
WO (1) WO2001090700A2 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8858787B2 (en) 2007-10-22 2014-10-14 Baxter International Inc. Dialysis system having non-invasive fluid velocity sensing

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6935192B2 (en) * 2003-09-30 2005-08-30 Agilent Technologies, Inc. Microfluidic bulk flow determinations based on converting heat tracer measurements
DE10356443A1 (en) * 2003-12-03 2005-07-07 Digmesa Ag Method and device for non-contact measuring of flow rates
DE102007054186B4 (en) * 2007-11-14 2012-04-12 Digmesa Ag Method and device for determining the flow of a flowing liquid
DE102010030143A1 (en) * 2010-06-16 2011-12-22 Deutsches Zentrum für Luft- und Raumfahrt e.V. Method for determining local flow rates of e.g. air, involves spatially and temporarily limiting energy of external fluid in flowing fluid or refractive index of flowing fluid to generate density fluctuation in flowing fluid
EP3812712B1 (en) * 2019-10-21 2024-04-24 Universität der Bundeswehr München Fluid flow analysis
CN113959950B (en) * 2021-10-28 2024-04-12 绍兴泊盛科技有限公司 Detection device for detecting liquid refractive index based on optofluidic chip

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950104A (en) * 1974-07-22 1976-04-13 Varian Associates Refractive index and flow rate detector and method
EP0232719A1 (en) * 1986-01-13 1987-08-19 Centra-Bürkle Gmbh Method and apparatus for the measurement of flow velocities
US5153665A (en) * 1991-06-14 1992-10-06 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Vaporizing particle velocimeter
DE19829940A1 (en) * 1998-07-04 2000-01-05 Martin Naegele Method and arrangement for measuring the spatial and temporal development of a laser-induced excitation in liquids / gases

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3950104A (en) * 1974-07-22 1976-04-13 Varian Associates Refractive index and flow rate detector and method
EP0232719A1 (en) * 1986-01-13 1987-08-19 Centra-Bürkle Gmbh Method and apparatus for the measurement of flow velocities
US5153665A (en) * 1991-06-14 1992-10-06 The United States Of America As Represented By The Administrator Of The National Aeronautics And Space Administration Vaporizing particle velocimeter
DE19829940A1 (en) * 1998-07-04 2000-01-05 Martin Naegele Method and arrangement for measuring the spatial and temporal development of a laser-induced excitation in liquids / gases

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8858787B2 (en) 2007-10-22 2014-10-14 Baxter International Inc. Dialysis system having non-invasive fluid velocity sensing

Also Published As

Publication number Publication date
AU2001274919A1 (en) 2001-12-03
WO2001090700A2 (en) 2001-11-29

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