WO2001087277A3 - Procede de fabrication de particules - Google Patents

Procede de fabrication de particules Download PDF

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Publication number
WO2001087277A3
WO2001087277A3 PCT/GB2001/002137 GB0102137W WO0187277A3 WO 2001087277 A3 WO2001087277 A3 WO 2001087277A3 GB 0102137 W GB0102137 W GB 0102137W WO 0187277 A3 WO0187277 A3 WO 0187277A3
Authority
WO
WIPO (PCT)
Prior art keywords
powders
manufacturing particles
active material
solution
low
Prior art date
Application number
PCT/GB2001/002137
Other languages
English (en)
Other versions
WO2001087277A2 (fr
Inventor
David Alexander Vodden Morton
Original Assignee
Vectura Ltd
David Alexander Vodden Morton
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0011712A external-priority patent/GB0011712D0/en
Priority claimed from GB0029265A external-priority patent/GB0029265D0/en
Application filed by Vectura Ltd, David Alexander Vodden Morton filed Critical Vectura Ltd
Priority to AU2001254995A priority Critical patent/AU2001254995A1/en
Publication of WO2001087277A2 publication Critical patent/WO2001087277A2/fr
Publication of WO2001087277A3 publication Critical patent/WO2001087277A3/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1688—Processes resulting in pure drug agglomerate optionally containing up to 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Otolaryngology (AREA)
  • Pulmonology (AREA)
  • Medicinal Preparation (AREA)

Abstract

La présente invention concerne des poudres de matière active sur le plan pharmaceutique. Le procédé de préparation de ces poudres consiste d'abord à fournir une solution qui contient cette matière active et une fraction à bas point d'ébullition, à expulser ensuite cette solution par un orifice pour former des gouttelettes, puis à permettre à la fraction à bas point d'ébullition de s'évaporer, et enfin, à collecter les particules ainsi formées. On peut utiliser ces poudres dans des poudres médicinales à inhaler.
PCT/GB2001/002137 2000-05-15 2001-05-15 Procede de fabrication de particules WO2001087277A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001254995A AU2001254995A1 (en) 2000-05-15 2001-05-15 Method of manufacturing particles

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
GB0011712.7 2000-05-15
GB0011712A GB0011712D0 (en) 2000-05-15 2000-05-15 Method of manufacturing particles
GB0029265.6 2000-11-30
GB0029265A GB0029265D0 (en) 2000-11-30 2000-11-30 Method of manufacturing particles

Publications (2)

Publication Number Publication Date
WO2001087277A2 WO2001087277A2 (fr) 2001-11-22
WO2001087277A3 true WO2001087277A3 (fr) 2002-04-04

Family

ID=26244273

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2001/002137 WO2001087277A2 (fr) 2000-05-15 2001-05-15 Procede de fabrication de particules

Country Status (2)

Country Link
AU (1) AU2001254995A1 (fr)
WO (1) WO2001087277A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004073827A1 (fr) * 2003-02-21 2004-09-02 The University Of Bath Procede de production de particules
GB0801876D0 (en) 2008-02-01 2008-03-12 Vectura Group Plc Suspension formulations

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995021688A1 (fr) * 1994-02-15 1995-08-17 Eckhard Weidner Procede pour la fabrication de particules ou de poudres
WO1998016204A1 (fr) * 1996-10-14 1998-04-23 F. Hoffmann-La Roche Ag Procede destine a la fabrication d'une preparation en poudre
WO1999016419A1 (fr) * 1997-09-29 1999-04-08 Inhale Therapeutic Systems, Inc. Microparticules perforees et procedes d'utilisation
WO1999042124A1 (fr) * 1998-02-20 1999-08-26 Inhale Therapeutic Systems, Inc. Cyclosporine en cristaux liquides
WO2000000176A1 (fr) * 1998-06-30 2000-01-06 Quadrant Healthcare (Uk) Limited Formulation a microparticules pour inhalation
WO2000074653A1 (fr) * 1999-06-04 2000-12-14 Skyepharma, Inc. Compositions a noyau huileux destinees a la liberation prolongee de medicaments hydrophobes
WO2001003671A2 (fr) * 1999-07-13 2001-01-18 Skw Trostberg Aktiengesellschaft Procede de preparation de formulations pulverulentes a taux particulaire reduit a l'aide de gaz comprimes

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1995021688A1 (fr) * 1994-02-15 1995-08-17 Eckhard Weidner Procede pour la fabrication de particules ou de poudres
WO1998016204A1 (fr) * 1996-10-14 1998-04-23 F. Hoffmann-La Roche Ag Procede destine a la fabrication d'une preparation en poudre
WO1999016419A1 (fr) * 1997-09-29 1999-04-08 Inhale Therapeutic Systems, Inc. Microparticules perforees et procedes d'utilisation
WO1999042124A1 (fr) * 1998-02-20 1999-08-26 Inhale Therapeutic Systems, Inc. Cyclosporine en cristaux liquides
WO2000000176A1 (fr) * 1998-06-30 2000-01-06 Quadrant Healthcare (Uk) Limited Formulation a microparticules pour inhalation
WO2000074653A1 (fr) * 1999-06-04 2000-12-14 Skyepharma, Inc. Compositions a noyau huileux destinees a la liberation prolongee de medicaments hydrophobes
WO2001003671A2 (fr) * 1999-07-13 2001-01-18 Skw Trostberg Aktiengesellschaft Procede de preparation de formulations pulverulentes a taux particulaire reduit a l'aide de gaz comprimes

Also Published As

Publication number Publication date
AU2001254995A1 (en) 2001-11-26
WO2001087277A2 (fr) 2001-11-22

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