WO2001085022A3 - Optical computed tomography in a turbid media - Google Patents

Optical computed tomography in a turbid media Download PDF

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Publication number
WO2001085022A3
WO2001085022A3 PCT/US2001/014643 US0114643W WO0185022A3 WO 2001085022 A3 WO2001085022 A3 WO 2001085022A3 US 0114643 W US0114643 W US 0114643W WO 0185022 A3 WO0185022 A3 WO 0185022A3
Authority
WO
WIPO (PCT)
Prior art keywords
computed tomography
psf
generalized
turbid medium
scattering
Prior art date
Application number
PCT/US2001/014643
Other languages
French (fr)
Other versions
WO2001085022A2 (en
Inventor
Kun Chen
Ramachandra R Dasari
Michael S Feld
Lev T Perelman
Qingguo Zhang
Original Assignee
Massachusetts Inst Technology
Kun Chen
Ramachandra R Dasari
Michael S Feld
Lev T Perelman
Qingguo Zhang
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Massachusetts Inst Technology, Kun Chen, Ramachandra R Dasari, Michael S Feld, Lev T Perelman, Qingguo Zhang filed Critical Massachusetts Inst Technology
Priority to JP2001581684A priority Critical patent/JP2003532873A/en
Priority to EP01933109A priority patent/EP1278454A2/en
Priority to CA002408239A priority patent/CA2408239A1/en
Priority to AU2001259559A priority patent/AU2001259559A1/en
Publication of WO2001085022A2 publication Critical patent/WO2001085022A2/en
Publication of WO2001085022A3 publication Critical patent/WO2001085022A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
    • G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
    • G01N21/47—Scattering, i.e. diffuse reflection
    • G01N21/4795—Scattering, i.e. diffuse reflection spatially resolved investigating of object in scattering medium
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00—Measuring for diagnostic purposes; Identification of persons
    • A61B5/0059—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence
    • A61B5/0073—Measuring for diagnostic purposes; Identification of persons using light, e.g. diagnosis by transillumination, diascopy, fluorescence by tomography, i.e. reconstruction of 3D images from 2D projections

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Physics & Mathematics (AREA)
  • General Health & Medical Sciences (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Optics & Photonics (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Radiology & Medical Imaging (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Image Input (AREA)

Abstract

Photon migration methods are employed to image absorbing objects embedded in a turbid medium such as tissue. For improved resolution, early arriving photons are detected to provide data with image reconstruction based on optical computed tomography (CT). The CT method is generalized to take into account the distributions of photon paths. A point spread function (PSF) is expressed in terms of the Green's function for the transport equation. This PSF provides weighting functions for use in a generalized series expansion method. Measurements of turbid medium with scattering and absorption properties included coaxial transmission scans collected in two projections. Blurring associated with multiple scattering was removed and high-resolution images can be obtained.
PCT/US2001/014643 2000-05-05 2001-05-04 Optical computed tomography in a turbid media WO2001085022A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
JP2001581684A JP2003532873A (en) 2000-05-05 2001-05-04 Optical computed tomography in opaque media
EP01933109A EP1278454A2 (en) 2000-05-05 2001-05-04 Optical computed tomography in a turbid media
CA002408239A CA2408239A1 (en) 2000-05-05 2001-05-04 Optical computed tomography in a turbid media
AU2001259559A AU2001259559A1 (en) 2000-05-05 2001-05-04 Optical computed tomography in a turbid media

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US20193800P 2000-05-05 2000-05-05
US60/201,938 2000-05-05

Publications (2)

Publication Number Publication Date
WO2001085022A2 WO2001085022A2 (en) 2001-11-15
WO2001085022A3 true WO2001085022A3 (en) 2002-04-04

Family

ID=22747900

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/014643 WO2001085022A2 (en) 2000-05-05 2001-05-04 Optical computed tomography in a turbid media

Country Status (6)

Country Link
EP (1) EP1278454A2 (en)
JP (1) JP2003532873A (en)
CN (1) CN1427690A (en)
AU (1) AU2001259559A1 (en)
CA (1) CA2408239A1 (en)
WO (1) WO2001085022A2 (en)

Cited By (6)

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US8976190B1 (en) 2013-03-15 2015-03-10 Pme Ip Australia Pty Ltd Method and system for rule based display of sets of images
US9167027B2 (en) 2007-08-27 2015-10-20 PME IP Pty Ltd Fast file server methods and systems
US9355616B2 (en) 2007-11-23 2016-05-31 PME IP Pty Ltd Multi-user multi-GPU render server apparatus and methods
US9454813B2 (en) 2007-11-23 2016-09-27 PME IP Pty Ltd Image segmentation assignment of a volume by comparing and correlating slice histograms with an anatomic atlas of average histograms
US9509802B1 (en) 2013-03-15 2016-11-29 PME IP Pty Ltd Method and system FPOR transferring data to improve responsiveness when sending large data sets
US9595242B1 (en) 2007-11-23 2017-03-14 PME IP Pty Ltd Client-server visualization system with hybrid data processing

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Publication number Priority date Publication date Assignee Title
EP2120687A1 (en) * 2006-12-19 2009-11-25 Koninklijke Philips Electronics N.V. Imaging of a turbid medium
US10311541B2 (en) 2007-11-23 2019-06-04 PME IP Pty Ltd Multi-user multi-GPU render server apparatus and methods
US9904969B1 (en) 2007-11-23 2018-02-27 PME IP Pty Ltd Multi-user multi-GPU render server apparatus and methods
CN101543398B (en) * 2008-03-26 2011-04-13 中国科学院自动化研究所 Target detection device based on exponential photon density dynamic adjustment
CN102144154B (en) * 2008-10-01 2015-04-22 东卡莱罗纳大学 Methods and systems for optically characterizing a turbid material using a structured incident beam
US10070839B2 (en) 2013-03-15 2018-09-11 PME IP Pty Ltd Apparatus and system for rule based visualization of digital breast tomosynthesis and other volumetric images
US10540803B2 (en) 2013-03-15 2020-01-21 PME IP Pty Ltd Method and system for rule-based display of sets of images
US11244495B2 (en) 2013-03-15 2022-02-08 PME IP Pty Ltd Method and system for rule based display of sets of images using image content derived parameters
US11183292B2 (en) 2013-03-15 2021-11-23 PME IP Pty Ltd Method and system for rule-based anonymized display and data export
CN103169452B (en) * 2013-04-03 2015-01-14 华中科技大学 Fast multipole boundary element method for processing diffusion optical tomography imaging forward direction process
US11599672B2 (en) 2015-07-31 2023-03-07 PME IP Pty Ltd Method and apparatus for anonymized display and data export
US9984478B2 (en) 2015-07-28 2018-05-29 PME IP Pty Ltd Apparatus and method for visualizing digital breast tomosynthesis and other volumetric images
US10909679B2 (en) 2017-09-24 2021-02-02 PME IP Pty Ltd Method and system for rule based display of sets of images using image content derived parameters
NL2020483B1 (en) * 2018-02-22 2019-08-29 Univ Delft Tech Method and apparatus for optical coherence projection tomography
WO2020222304A1 (en) * 2019-04-30 2020-11-05 Atonarp Inc. Measuring system

Citations (1)

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Publication number Priority date Publication date Assignee Title
US5931789A (en) * 1996-03-18 1999-08-03 The Research Foundation City College Of New York Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5919140A (en) 1995-02-21 1999-07-06 Massachusetts Institute Of Technology Optical imaging using time gated scattered light

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5931789A (en) * 1996-03-18 1999-08-03 The Research Foundation City College Of New York Time-resolved diffusion tomographic 2D and 3D imaging in highly scattering turbid media

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHERNOMORDIK V ET AL: "Point spread functions of photons in time-resolved transillumination experiments using simple scaling arguments", MEDICAL PHYSICS, AIP FOR AMERICAN ASSOC. PHYS. MED, USA, vol. 23, no. 11, November 1996 (1996-11-01), pages 1857 - 1861, XP002181094, ISSN: 0094-2405 *
COLAK S B ET AL: "TOMOGRAPHIC IMAGE RECONSTRUCTION FROM OPTICAL PROJECTIONS IN LIGHT-DIFFUSING MEDIA", APPLIED OPTICS, XX, XX, vol. 36, 1 January 1997 (1997-01-01), pages 180 - 213, XP000942934, ISSN: 0003-6935 *
KUN CHEN ET AL: "Optical computed tomography in a turbid medium using early arriving photons", JOURNAL OF BIOMEDICAL OPTICS, SPIE, USA, vol. 5, no. 2, April 2000 (2000-04-01), pages 144 - 154, XP002181092, ISSN: 1083-3668 *
WINN J N ET AL: "Distribution of the paths of early-arriving photons traversing a turbid medium", APPLIED OPTICS, 1 DEC. 1998, OPT. SOC. AMERICA, USA, vol. 37, no. 34, pages 8085 - 8091, XP002181093, ISSN: 0003-6935 *

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9167027B2 (en) 2007-08-27 2015-10-20 PME IP Pty Ltd Fast file server methods and systems
US9531789B2 (en) 2007-08-27 2016-12-27 PME IP Pty Ltd Fast file server methods and systems
US9355616B2 (en) 2007-11-23 2016-05-31 PME IP Pty Ltd Multi-user multi-GPU render server apparatus and methods
US9454813B2 (en) 2007-11-23 2016-09-27 PME IP Pty Ltd Image segmentation assignment of a volume by comparing and correlating slice histograms with an anatomic atlas of average histograms
US9595242B1 (en) 2007-11-23 2017-03-14 PME IP Pty Ltd Client-server visualization system with hybrid data processing
US8976190B1 (en) 2013-03-15 2015-03-10 Pme Ip Australia Pty Ltd Method and system for rule based display of sets of images
US9509802B1 (en) 2013-03-15 2016-11-29 PME IP Pty Ltd Method and system FPOR transferring data to improve responsiveness when sending large data sets
US9524577B1 (en) 2013-03-15 2016-12-20 PME IP Pty Ltd Method and system for rule based display of sets of images

Also Published As

Publication number Publication date
EP1278454A2 (en) 2003-01-29
WO2001085022A2 (en) 2001-11-15
AU2001259559A1 (en) 2001-11-20
JP2003532873A (en) 2003-11-05
CN1427690A (en) 2003-07-02
CA2408239A1 (en) 2001-11-15

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