WO2001081368A3 - Polypeptides reduisant la tension sanguine et contenant vpp derives a partir de micro-organismes - Google Patents

Polypeptides reduisant la tension sanguine et contenant vpp derives a partir de micro-organismes Download PDF

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Publication number
WO2001081368A3
WO2001081368A3 PCT/US2001/012776 US0112776W WO0181368A3 WO 2001081368 A3 WO2001081368 A3 WO 2001081368A3 US 0112776 W US0112776 W US 0112776W WO 0181368 A3 WO0181368 A3 WO 0181368A3
Authority
WO
WIPO (PCT)
Prior art keywords
microorganisms
blood
derived
pressure reducing
polypeptides containing
Prior art date
Application number
PCT/US2001/012776
Other languages
English (en)
Other versions
WO2001081368A2 (fr
Inventor
Joseph M Kobzeff
Original Assignee
Monsanto Technology Llc
Joseph M Kobzeff
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Monsanto Technology Llc, Joseph M Kobzeff filed Critical Monsanto Technology Llc
Priority to AU2001255501A priority Critical patent/AU2001255501A1/en
Publication of WO2001081368A2 publication Critical patent/WO2001081368A2/fr
Publication of WO2001081368A3 publication Critical patent/WO2001081368A3/fr

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0802—Tripeptides with the first amino acid being neutral
    • C07K5/0804—Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0808—Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms, e.g. Val, Ile, Leu
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
    • C12N9/18—Carboxylic ester hydrolases (3.1.1)
    • C12N9/20—Triglyceride splitting, e.g. by means of lipase
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

L'invention concerne un procédé de production d'un tripeptide VPP anti-hypertenseur. L'invention concerne également des compositions pharmaceutiques, nutritionnelles et alimentaires comprenant VPP en tant que principe actif.
PCT/US2001/012776 2000-04-21 2001-04-19 Polypeptides reduisant la tension sanguine et contenant vpp derives a partir de micro-organismes WO2001081368A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001255501A AU2001255501A1 (en) 2000-04-21 2001-04-19 Blood-pressure reducing polypeptides containing vpp derived from microorganisms

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19968000P 2000-04-21 2000-04-21
US60/199,680 2000-04-21

Publications (2)

Publication Number Publication Date
WO2001081368A2 WO2001081368A2 (fr) 2001-11-01
WO2001081368A3 true WO2001081368A3 (fr) 2002-05-16

Family

ID=22738560

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/012776 WO2001081368A2 (fr) 2000-04-21 2001-04-19 Polypeptides reduisant la tension sanguine et contenant vpp derives a partir de micro-organismes

Country Status (2)

Country Link
AU (1) AU2001255501A1 (fr)
WO (1) WO2001081368A2 (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI411441B (zh) * 2003-03-18 2013-10-11 Suntory Holdings Ltd 血管收縮素轉化酶抑制性肽類
US20070207944A1 (en) * 2004-07-12 2007-09-06 Luppo Edens Blood Pressure Lowering Oligopeptides
CN101084004A (zh) * 2004-12-22 2007-12-05 帝斯曼知识产权资产管理有限公司 单个酶促步骤中的血压降低寡肽
US20090042809A1 (en) * 2005-04-28 2009-02-12 Luppo Edens Blood Pressure Lowering Protein Hydrolysates

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583074A2 (fr) * 1992-07-23 1994-02-16 The Calpis Food Industry Co., Ltd. Inhibiteur de l'enzyme de conversion de l'angiotensine et procédé pour le préparer
WO1996017054A1 (fr) * 1994-12-01 1996-06-06 Oklahoma Medical Research Foundation Technique et compositions permettant de reduire l'absorption de cholesterol
WO1996037622A1 (fr) * 1995-05-24 1996-11-28 Astra Aktiebolag (Publ) Molecules d'adn pour l'expression de la lipase stimulee par les sels biliaires (bssl)

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0583074A2 (fr) * 1992-07-23 1994-02-16 The Calpis Food Industry Co., Ltd. Inhibiteur de l'enzyme de conversion de l'angiotensine et procédé pour le préparer
WO1996017054A1 (fr) * 1994-12-01 1996-06-06 Oklahoma Medical Research Foundation Technique et compositions permettant de reduire l'absorption de cholesterol
WO1996037622A1 (fr) * 1995-05-24 1996-11-28 Astra Aktiebolag (Publ) Molecules d'adn pour l'expression de la lipase stimulee par les sels biliaires (bssl)

Also Published As

Publication number Publication date
WO2001081368A2 (fr) 2001-11-01
AU2001255501A1 (en) 2001-11-07

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