WO2001080814A1 - Entailleur d'ongle a profondeur predeterminee et traitement des onychomycoses - Google Patents

Entailleur d'ongle a profondeur predeterminee et traitement des onychomycoses Download PDF

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Publication number
WO2001080814A1
WO2001080814A1 PCT/US2001/040550 US0140550W WO0180814A1 WO 2001080814 A1 WO2001080814 A1 WO 2001080814A1 US 0140550 W US0140550 W US 0140550W WO 0180814 A1 WO0180814 A1 WO 0180814A1
Authority
WO
WIPO (PCT)
Prior art keywords
nail
notch
cutting edge
medication
cutting
Prior art date
Application number
PCT/US2001/040550
Other languages
English (en)
Inventor
Leonard Feldman
Original Assignee
Profoot, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Profoot, Inc. filed Critical Profoot, Inc.
Priority to AU2001255857A priority Critical patent/AU2001255857A1/en
Publication of WO2001080814A1 publication Critical patent/WO2001080814A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q3/00—Manicure or pedicure preparations
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
    • A01N25/00—Biocides, pest repellants or attractants, or plant growth regulators, characterised by their forms, or by their non-active ingredients or by their methods of application, e.g. seed treatment or sequential application; Substances for reducing the noxious effect of the active ingredients to organisms other than pests
    • A01N25/34—Shaped forms, e.g. sheets, not provided for in any other sub-group of this main group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208—Tissues; Wipes; Patches

Definitions

  • the present invention relates to a system including a nail notcher for cutting a notch
  • invention also relates to a method for applying topical anti-fungal composition to fungus
  • a human's nail has a nail plate, which is a hard outer surface of dead cells, and a
  • the nail bed below the nail plate.
  • the nail plate is non-porous, whereas the nail bed is porous.
  • the nail plate and the nail bed are relatively soft flesh beneath the nail bed.
  • the nail plate and the nail bed are relatively soft flesh beneath the nail bed.
  • fungi Such fungi are responsible for nail infections, medically known as onychomycosis.
  • onychomycosis are caused by fungi, such as t ⁇ chophyton mentagrophytes,
  • Candida albicans or trichophyton rubr m Other terms for onychomycosis are ringworm of
  • Example 11 discloses onychomycosis treatment of a fingernail. However, the Example emphasizes that its preparation is suitable for treating superficial
  • U.S. Patent No. 5,696,105 discloses drilling holes in nails to apply anti-fungal
  • 5,696,105 also discloses other local measures to treat nail fungus include mechanical
  • the medicine is not concentrated in the infected area and may cause
  • toenail fungus which easily can be directly applied to the nail to result in effective, painless
  • the present invention relates to a system including a set
  • depth nail notcher for cutting a notch of predetermined depth in a fingernail or a toenail
  • the nail notcher comprises a handle having a smooth
  • the set depth nail notcher may provide a
  • the patch is an adhesive patch including a portion for being impregnated with
  • Any pad which is capable of holding the mediation is
  • the pad is supple and the adhesive
  • portion is flexible such that the patch will conform to the shape of the toe, finger and/or nail
  • the patch serves to protect the open notch from contamination as well as prevent
  • the patch may
  • the present invention involves a method for treating fingernail
  • the medication may be put on/into the patch before the patch is put on the notch, or
  • the medication may be put on/into the notch before the patch is put on the notch.
  • the method treats the infected nail to create a sterile antiseptic area proximal to the
  • the sterile area typically extend into the nail bed and may extend
  • Fig. 1 discloses a perspective bottom view of the first embodiment of the present
  • Fig. 2 discloses a perspective top view of the embodiment of Fig. 1.
  • Fig. 3 discloses a bottom view of the embodiment of Fig. 1.
  • Fig. 4 discloses a side view of the embodiment of Fig. 1.
  • Fig. 5 discloses a side view of a second embodiment of the present invention.
  • Fig. 6 discloses a front view of a third embodiment of the present invention.
  • Fig. 7 discloses a partial side view of a fourth embodiment of the present invention.
  • Fig. 8 discloses an infected toenail being treated according to the present invention.
  • Fig. 9 is a side view of a third embodiment of a nail notching device of the present
  • Fig. 10 is an enlarged view of the top side of a file pad of the embodiment of Fig.
  • Fig. 11 is an enlarged view of the bottom side of a file pad of the embodiment of Fig.
  • Fig. 12 is an enlarged view of the nail notching device of Fig. 9 in use.
  • Fig. 13 is a side view of a portion of a file edge of a file pad of the embodiment of
  • Fig. 14 is a cross-sectional front view of the file pad of Fig. 13.
  • Fig 15 is a cross-sectional side view of the file pad of Fig. 13.
  • Fig. 16 is a cross-sectional front view of the file pad of Fig. 13 modified to have a
  • Fig 17 is a cross-sectional side view of the file pad of Fig. 16.
  • Fig. 18 shows an example of a typical impregnated bandage that may be employed
  • Fig. 19 shows another embodiment of a typical patch which may be employed with
  • the nail notching device is designed to assist a patient, doctor, or technician
  • this notch is to allow a contemporaneous application of over-the-counter (or
  • topical antifungal liquid e.g., solution, gel or cream access to the soft tissue
  • Fig. 1 shows a first embodiment of a nail notcher 10 of the present invention.
  • nail notcher 10 has a file pad 11 (as a substrate) and a cutting edge 20.
  • the file pad 11 has
  • the cutting edge 20 protrudes from the smooth, flat bottom surface 12.
  • the cutting edge 20 may be
  • the file pad 11 is elongate and thus has a
  • the cutting edge 20 is also longitudinally arranged relative to the
  • the file pad 11 has a first end 16 and a second end 18. Likewise,
  • the cutting edge 20 has a first end 22 and a second end 24.
  • edge 20 may be at or adjacent the first end 16 of the file pad 11.
  • the second end 24 of the first end 16 of the file pad 11 may be at or adjacent the first end 16 of the file pad 11.
  • cutting edge 20 may also be at or adjacent to the second end 18 of the file pad 11.
  • Fig. 3 also shows the second end 24 of the cutting edge 20 being adjacent the second end
  • the cutting edge 20 includes edges which cut by
  • the cutting edge 20 may contain a straight edge, abrasive or
  • the edge may be a sharp straight edge (as shown in Fig. 3) or round (as shown in Fig. 3)
  • the nail notcher 10 is capable of producing
  • the cutting edge 20 may have a depth of about 0.5 to about 4 mm,
  • the nail notcher 10 is typically made of a material able to be autoclaved or sanitized.
  • the file pad 11 may be made of metal or plastic.
  • the cutting edge 20 is made of metal or plastic.
  • the nail notcher 10 can either be a flat nail
  • notcher 10 (as shown in Figs. 1-4) or be a curved nail notcher 110 (the second embodiment
  • notcher 10 also has a width "W" of from generally about 3/8 inch to about 1 inch.
  • the nail notcher 10 is sized for easy gripping and use. Thus, it may be provided
  • protrusions from the upper surface or the nail handle may have contoured side edges, etc.
  • Fig. 5 shows a second embodiment of the nail notcher 110 of the present invention
  • Curved nail notcher 110 also has a concave top surface 113. However, if desired, the top
  • Fig. 6 shows a third embodiment of a nail notcher 210 of the present invention
  • This embodiment is advantageous because it cuts
  • the groove may be wider than it is deep.
  • Fig. 7 shows a side view of a fourth embodiment of the present invention of a nail
  • notcher 310 having a handle 11 provided with a serrated cutting edge 320.
  • any of the above nail notchers may be employed to treat nail fungus.
  • a nail notcher may be employed to treat nail fungus.
  • nail notcher such as nail notcher 10
  • nail notcher 10 would be employed as follows. A patient or medical
  • the nail for the smooth flat bottom surface 12 to contact the nail bed.
  • two or three notches may be made in the same nail for application of medication to multiple
  • anti-fungal medication which is then absorbed and, preferably, permeates the nail bed.
  • the nail bed is the soft porous layer of the nail between the nail plate and the flesh below
  • the smooth flat bottom surface 12 prevents the cutting edge from cutting too deeply
  • the cutting edge 20 cuts into the nail bed and may cut to, but preferably
  • the present method is a bloodless procedure. Due to the porous
  • the notch may be sufficiently deep for applying medication for
  • depth stopping surface along at least one side of the length of the cutting edge 20 may be
  • the bottom surface may comprise ribs (not shown) parallel to the
  • the medication could be any of the FDA
  • the topical medication would be placed into the notch (or
  • anti-fungal medications which may be employed with the nail notcher 10 of the present
  • inventions include chlortrimizol, tolnaftate and undecylenate acid.
  • stabilizers preservatives, whiteners, buffers and surfactants may be used in the formulations
  • the antifungal composition may be in the form of
  • liquid e.g., solution, gel, semi-solid, cream or solid. It also may be applied as one form,
  • the present invention penetrates the nail plate to expose the nail bed, by an
  • notches 132, 134, 136 are cut with nail notcher 10
  • FIG. 8 shows fungus infecting a distal region 130, relative to the cuticle
  • Notch 132 is cut into the infected region 130 in a direction
  • Notches 134, 136 are cut
  • toenail 128 may be filed to smooth its surface prior to cutting the notches into the surface.
  • At least one medicine which is a fungicide (kills fungus) or
  • a fungistat prevents fungus growth
  • the notches 132, 134, 136 are applied to the notches 132, 134, 136.
  • the medicine may not kill fungus. However, it at least
  • the treatment prevents its growth.
  • the treatment prevents the fungus in the infected portion 130
  • Figs. 9-17 show another embodiment of a nail notcher device 208 useful in the
  • the nail notcher device 408 (Fig. 9) is a hand-held, one-piece tool
  • elongated center handle grip 411 preferably constructed of milled stainless steel.
  • angled file pads 410 at either end.
  • the file pads 410 have a smooth bottom surface 412 and a top grip
  • Each file pad 410 has a first end 416 and a second end 418 (Fig. 11).
  • top grip surface 413 may be any suitable surface, smooth or rough, i.e. , textured. However,
  • Fig. 10 shows top grip surface 413 having channels
  • Each file pad 410 includes a bottom surface 412 having a smooth polished surface
  • File edge 420 is latitudinal relative to the handle grip 411 but longitudinal
  • the file edges each have a first end 422 and a
  • File edges 420 have peaks 425 of
  • Each file edge 420 may have the
  • each file edge 420 may be made of the same or different materials relative
  • one end of the grip 411 may have file pad 410 while the other end of
  • the grip 411 has file pad 410A which is the same as file pad 410 except for having an edge
  • Heights B, D typically range from
  • the angle "A" of the valleys 423 between the peaks of edges 420 or 420A generally ranges from about 0.25 mm to about 2 mm less than the respective height B, C.
  • the angle "A" of the valleys 423 between the peaks of edges 420 or 420A generally range
  • Angle "A” is defined as the angle
  • the file edge 420 as shown is metal cut with valleys 423 to form a file surface.
  • an abrasive-coated edge would also provide a file edge. If desired, a sharp edge
  • cutting edge could be substituted for the file edge 420.
  • the length "LL" of the elongated center grip 411 generally ranges from about 2
  • the length "M" (Fig. 9) of the knurled surface 415 generally
  • the two file edges 420 generally ranges from 0.25 inch to about 1 inch.
  • the two file edges 420 are generally ranges from 0.25 inch to about 1 inch.
  • 420A may have respective heights B, D of 1.2 mm and 1.8 mm.
  • the nail notching device 408 is designed to be extremely easy and safe to use. Its
  • the file edge is finely milled, and requires a minimal amount of pressure to abrade a precise notch. Additionally, the elongated handle makes the nail notching device 408 easier
  • the self limiting file edge prevents any possibility of a deep wound or "over-
  • the nail notching device 408 is sturdily constructed of one continuous piece of high quality
  • the nail notcher / patch system may be provided as a kit.
  • the nail notcher / patch system may be provided as a kit.
  • the anti-fungal medication may be an ointment, a
  • medication may be in the form of a sustained release formulation.
  • the composition of such a sustained release formulation may be in the form of a sustained release formulation.
  • a suitable sustained release formulation would be known to those skilled in the art.
  • the patch is impregnated prior to use, then it is sold in a sealed package (not
  • the patch is impregnated during use, then it could be sold in a kit containing the
  • Suitable packaging for a dry patch could be such as that used to package
  • the medication may be applied to the notch and then a patch, such as an
  • a transdermal system for delivering nicotine, not anti-fungal medication is disclosed
  • anti-fungal medication would typically comprise an occlusive pad which is capable of
  • occlusive pad comprising an anti-fungal medication-impermeable backing and an anti-
  • the cavity containing a liquid anti-fungal medication.
  • the bandage 610 has a width of about
  • medication impermeable backing 612 formed of a suitable, preferably flexible and
  • impervious plastic or rubber material such as a polyvinylidene chloride, polyethylene, polypropylene, nylon, silicone rubber, etc., having a cavity 614 along one surface thereof.
  • liquid anti-fungal medication 616 is provided within the cavity 614 .
  • Sealing the medication is a film 618 again formed of a suitable microporous and flexible
  • a suitable adhesive 620 is provided on
  • the bandage 610 may be kept sealed in an air tight pouch prior to use to prevent drying
  • a suitable absorbent material such as cotton or sponge (not shown) may be in
  • topical anti-fungal medication to a nail notch.
  • Fig. 18 shows an example of a typical impregnated bandage 500 having a gauze pad
  • portions 520 are made of polymer. However, any suitable bandage or tape may be
  • the adhesive coating may be any coating used to removably adhere to skin for
  • Portions of the flexible portion 520 extend from opposed sides of the pad 510.
  • the pad and the adhesive portion can bend such that the patch 500 will conform
  • the present invention is a major advance in treating nail, especially toenail, fungus
  • the patch serves to protect the open notch from contamination as well as prevent
  • the patch may

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Plant Pathology (AREA)
  • Pest Control & Pesticides (AREA)
  • Toxicology (AREA)
  • Agronomy & Crop Science (AREA)
  • Dentistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Environmental Sciences (AREA)
  • Biomedical Technology (AREA)
  • Birds (AREA)
  • Epidemiology (AREA)
  • Medicinal Preparation (AREA)

Abstract

L'invention concerne une trousse comprenant un timbre adhésif chargé d'un médicament antifongique et un entailleur d'ongle à hauteur prédéterminée permettant de pratiquer un entaille d'une profondeur prédéterminée dans le limbe unguéal. Cet entailleur comprend un manche présentant une surface plane et lisse, un bord de coupe longitudinal émergeant de cette surface plate et lisse à une hauteur équivalente à la profondeur prédéterminée de l'entaille. L'invention concerne également une méthode permettant de traiter une onychomycose, en particulier une onychomycose du pied, consistant à pratiquer une entaille à une profondeur prédéterminée dans l'ongle de l'orteil ou du doigt infecté par une mycose et à appliquer un médicament anti-fongique topique sur l'orteil ou sur le doigt à travers l'entaille par le biais du timbre.
PCT/US2001/040550 2000-04-20 2001-04-19 Entailleur d'ongle a profondeur predeterminee et traitement des onychomycoses WO2001080814A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001255857A AU2001255857A1 (en) 2000-04-20 2001-04-19 Set depth nail notcher with patch system and method for treating nail fungus

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US19857600P 2000-04-20 2000-04-20
US60/198,576 2000-04-20

Publications (1)

Publication Number Publication Date
WO2001080814A1 true WO2001080814A1 (fr) 2001-11-01

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ID=22733957

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/040550 WO2001080814A1 (fr) 2000-04-20 2001-04-19 Entailleur d'ongle a profondeur predeterminee et traitement des onychomycoses

Country Status (2)

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AU (1) AU2001255857A1 (fr)
WO (1) WO2001080814A1 (fr)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005191A (en) * 1974-06-04 1977-01-25 Clark Mary G Topical ointment composition
US5696105A (en) * 1996-03-14 1997-12-09 Hackler; Walter A. Antifungal nail composition

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4005191A (en) * 1974-06-04 1977-01-25 Clark Mary G Topical ointment composition
US5696105A (en) * 1996-03-14 1997-12-09 Hackler; Walter A. Antifungal nail composition

Also Published As

Publication number Publication date
AU2001255857A1 (en) 2001-11-07

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