WO2001079426A3 - A new polypeptide-human locomotor telangiectasis atm protein 20 and the polynucleotide encoding it - Google Patents
A new polypeptide-human locomotor telangiectasis atm protein 20 and the polynucleotide encoding it Download PDFInfo
- Publication number
- WO2001079426A3 WO2001079426A3 PCT/CN2001/000370 CN0100370W WO0179426A3 WO 2001079426 A3 WO2001079426 A3 WO 2001079426A3 CN 0100370 W CN0100370 W CN 0100370W WO 0179426 A3 WO0179426 A3 WO 0179426A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polynucleotide encoding
- present
- atm protein
- polypeptide
- telangiectasis
- Prior art date
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Toxicology (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
The present invention disclose a new polypeptide-human locomotor ataxia telangiectasia ATM protein 20, the polynucleotide encoding it and a method producing the polypeptide by DNA recombinant technology. The present invention further disclose a method treating various disorders, e.g., ataxia telangiectasia, breast carcinoma, leucoma, other carcinoma, immunological disease, developmental disorder, inflammation, hematopathy, HIV infection etc. The present invention also disclose an antagonist of the polypeptide and its therapeutic action. The present invention further disclose the use of the polynucleotide encoding the new human locomotor ataxia telangiectasia ATM protein 20.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU56052/01A AU5605201A (en) | 2000-03-22 | 2001-03-19 | A novel polypeptide, a human kinetic ataxia telangiectasia protein atm20 and thepolynucleotide encoding the polypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00115022.7 | 2000-03-22 | ||
| CN00115022A CN1314381A (en) | 2000-03-22 | 2000-03-22 | New polypeptide-human kinetic ataxia-telangiectasis ATM protein 20 and polynucleotide for coding such polypeptide |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001079426A2 WO2001079426A2 (en) | 2001-10-25 |
| WO2001079426A3 true WO2001079426A3 (en) | 2002-02-07 |
Family
ID=4584493
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000370 WO2001079426A2 (en) | 2000-03-22 | 2001-03-19 | A new polypeptide-human locomotor telangiectasis atm protein 20 and the polynucleotide encoding it |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1314381A (en) |
| AU (1) | AU5605201A (en) |
| WO (1) | WO2001079426A2 (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104178487B (en) * | 2013-05-20 | 2017-09-19 | 中南大学湘雅医院 | ATM gene mutation bodies and its application |
-
2000
- 2000-03-22 CN CN00115022A patent/CN1314381A/en active Pending
-
2001
- 2001-03-19 WO PCT/CN2001/000370 patent/WO2001079426A2/en active Application Filing
- 2001-03-19 AU AU56052/01A patent/AU5605201A/en not_active Abandoned
Non-Patent Citations (5)
| Title |
|---|
| BLACK G.C. ET AL.: "Coats' disease of the retina (unilateral retinal telangiectasis) caused by somatic mutation in the NDP gene: a role for norrin in retinal angiogenesis", HUM. MOL. GENET., vol. 8, no. 11, 1999, pages 2031 - 2035 * |
| CLAVERIE J.M. AND MAKALOWSKI W.: "Alu alert", NATURE, vol. 371, no. 6500, 1994, pages 752 * |
| DATABASE GENBANK [online] 19 October 1999 (1999-10-19), "Homo sapiens chromosome 14 BAC 98L12", Database accession no. AC008015 * |
| FUCHS S. ET AL.: "A missense point mutation (Leu13Arg) of the Norrie disease gene in a large Cuban kindred with Norrie disease", HUM. MOL. GENET., vol. 3, no. 4, 1994, pages 655 - 656 * |
| MATSUMURA M. ET AL.: "Stabilization of phage T4 lysozyme by engineered disulfide bonds", PROC. NATL. ACAD. SCI. USA, vol. 86, no. 17, 1989, pages 6562 - 6566 * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU5605201A (en) | 2001-10-30 |
| CN1314381A (en) | 2001-09-26 |
| WO2001079426A2 (en) | 2001-10-25 |
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