WO2001075052A3 - A novel polypeptide, nadh dehydrogenase human sub-unit i-17 and the polynucleotide encoding the polypeptide - Google Patents

A novel polypeptide, nadh dehydrogenase human sub-unit i-17 and the polynucleotide encoding the polypeptide Download PDF

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Publication number
WO2001075052A3
WO2001075052A3 PCT/CN2001/000498 CN0100498W WO0175052A3 WO 2001075052 A3 WO2001075052 A3 WO 2001075052A3 CN 0100498 W CN0100498 W CN 0100498W WO 0175052 A3 WO0175052 A3 WO 0175052A3
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WO
WIPO (PCT)
Prior art keywords
polypeptide
unit
polynucleotide encoding
nadh dehydrogenase
discloses
Prior art date
Application number
PCT/CN2001/000498
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001075052A2 (en
Inventor
Yumin Mao
Yi Xie
Original Assignee
Shanghai Biowindow Gene Dev
Yumin Mao
Yi Xie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shanghai Biowindow Gene Dev, Yumin Mao, Yi Xie filed Critical Shanghai Biowindow Gene Dev
Priority to AU63726/01A priority Critical patent/AU6372601A/en
Publication of WO2001075052A2 publication Critical patent/WO2001075052A2/en
Publication of WO2001075052A3 publication Critical patent/WO2001075052A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
    • C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention discloses a novel polypeptide, a NADH dehydrogenase human sub-unit I-17, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for treating various diseases, such as malignant tumor, hemopathy, HIV infection, immunological disease, and various inflammation, etc. The invention also discloses the agonists against the polypeptide and the therapeutic action thereof. The invention also discloses the uses of the polynucleotide encoding the NADH dehydrogenase human sub-unit I-17.
PCT/CN2001/000498 2000-03-27 2001-03-26 A novel polypeptide, nadh dehydrogenase human sub-unit i-17 and the polynucleotide encoding the polypeptide WO2001075052A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU63726/01A AU6372601A (en) 2000-03-27 2001-03-26 A novel polypeptide, nadh dehydrogenase human sub-unit i-17 and the polynucleotide encoding the polypeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN 00115140 CN1315369A (en) 2000-03-27 2000-03-27 Polypeptide-human NADH dehydrogenase subunit I-17 and polynucleotide for coding it

Publications (2)

Publication Number Publication Date
WO2001075052A2 WO2001075052A2 (en) 2001-10-11
WO2001075052A3 true WO2001075052A3 (en) 2002-04-18

Family

ID=4584609

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000498 WO2001075052A2 (en) 2000-03-27 2001-03-26 A novel polypeptide, nadh dehydrogenase human sub-unit i-17 and the polynucleotide encoding the polypeptide

Country Status (3)

Country Link
CN (1) CN1315369A (en)
AU (1) AU6372601A (en)
WO (1) WO2001075052A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925543A (en) * 1997-09-12 1999-07-20 Incyte Pharmaceuticals, Inc. Isolated polynucleotide sequence encoding NADH dehydrogenase B17 subunit
US5976804A (en) * 1997-12-12 1999-11-02 Incyte Pharmaceuticals, Inc. NADH dehydrogenase PDSW subunit

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925543A (en) * 1997-09-12 1999-07-20 Incyte Pharmaceuticals, Inc. Isolated polynucleotide sequence encoding NADH dehydrogenase B17 subunit
US6100036A (en) * 1997-09-12 2000-08-08 Incyte Pharmaceuticals, Inc. NADH dehydrogenase B17 subunit
US5976804A (en) * 1997-12-12 1999-11-02 Incyte Pharmaceuticals, Inc. NADH dehydrogenase PDSW subunit

Also Published As

Publication number Publication date
WO2001075052A2 (en) 2001-10-11
AU6372601A (en) 2001-10-15
CN1315369A (en) 2001-10-03

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