WO2001075026A3 - A novel polypeptide, human eucaryotic acetyl transferase 10 and the polynucleotide encoding the polypeptide - Google Patents

A novel polypeptide, human eucaryotic acetyl transferase 10 and the polynucleotide encoding the polypeptide Download PDF

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Publication number
WO2001075026A3
WO2001075026A3 PCT/CN2001/000378 CN0100378W WO0175026A3 WO 2001075026 A3 WO2001075026 A3 WO 2001075026A3 CN 0100378 W CN0100378 W CN 0100378W WO 0175026 A3 WO0175026 A3 WO 0175026A3
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WO
WIPO (PCT)
Prior art keywords
polypeptide
polynucleotide encoding
acetyl transferase
discloses
human eucaryotic
Prior art date
Application number
PCT/CN2001/000378
Other languages
French (fr)
Chinese (zh)
Other versions
WO2001075026A2 (en
Inventor
Yumin Mao
Yi Xie
Original Assignee
Biowindow Gene Dev Inc
Yumin Mao
Yi Xie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biowindow Gene Dev Inc, Yumin Mao, Yi Xie filed Critical Biowindow Gene Dev Inc
Priority to AU58146/01A priority Critical patent/AU5814601A/en
Publication of WO2001075026A2 publication Critical patent/WO2001075026A2/en
Publication of WO2001075026A3 publication Critical patent/WO2001075026A3/en

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10Transferases (2.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Molecular Biology (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

The present invention discloses a novel polypeptide, a human eucaryotic acetyl transferase 10, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for treating various diseases, such as malignant tumor, hemopathy, HIV infection, immunological disease, and various inflammation, etc. The invention also discloses the agonists against the polypeptide and the therapeutic action thereof. The invention also discloses the uses of the polynucleotide encoding the human eucaryotic acetyl transferase 10.
PCT/CN2001/000378 2000-03-22 2001-03-19 A novel polypeptide, human eucaryotic acetyl transferase 10 and the polynucleotide encoding the polypeptide WO2001075026A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU58146/01A AU5814601A (en) 2000-03-22 2001-03-19 A novel polypeptide, human eucaryotic acetyl transferase 10 and the polynucleotide encoding the polypeptide

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CN00115031A CN1314481A (en) 2000-03-22 2000-03-22 New polypeptide-human eucaryotic acetyl transferase 10 and polynucleotide for coding such polypeptide
CN00115031.6 2000-03-22

Publications (2)

Publication Number Publication Date
WO2001075026A2 WO2001075026A2 (en) 2001-10-11
WO2001075026A3 true WO2001075026A3 (en) 2002-01-03

Family

ID=4584502

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CN2001/000378 WO2001075026A2 (en) 2000-03-22 2001-03-19 A novel polypeptide, human eucaryotic acetyl transferase 10 and the polynucleotide encoding the polypeptide

Country Status (3)

Country Link
CN (1) CN1314481A (en)
AU (1) AU5814601A (en)
WO (1) WO2001075026A2 (en)

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
CLAVERIE J.M. AND MAKALOWSKI W.: "Alu alert", NATURE, vol. 371, no. 6500, 1994, pages 752 *
LAU K.S. ET AL.: "Premature termination of transcription and alternative splicing in the human transacylase (E2) gene of the branched-chain alpha-keto acid dehydrogenase complex", FEBS LETT., vol. 279, no. 2, 1991, pages 229 - 232 *
LAU K.S. ET AL.: "Structure of the gene encoding dihydrolipoyl transacylase (E2) component of human branched chain alpha-keto acid dehydrogenase complex and characterization of an E2 pseudogene", J. BIOL. CHEM., vol. 267, no. 33, 1992, pages 24090 - 24096 *

Also Published As

Publication number Publication date
AU5814601A (en) 2001-10-15
WO2001075026A2 (en) 2001-10-11
CN1314481A (en) 2001-09-26

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