WO2001075025A3 - A novel polypeptide, human thyroglobuline 9 and the polynuceotide encoding the polypeptide - Google Patents
A novel polypeptide, human thyroglobuline 9 and the polynuceotide encoding the polypeptide Download PDFInfo
- Publication number
- WO2001075025A3 WO2001075025A3 PCT/CN2001/000374 CN0100374W WO0175025A3 WO 2001075025 A3 WO2001075025 A3 WO 2001075025A3 CN 0100374 W CN0100374 W CN 0100374W WO 0175025 A3 WO0175025 A3 WO 0175025A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- polypeptide
- thyroglobuline
- human
- discloses
- novel
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/71—Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Immunology (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Toxicology (AREA)
- Biophysics (AREA)
- Cell Biology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Peptides Or Proteins (AREA)
Abstract
The present invention discloses a novel polypeptide, a human thyroglobuline 9, the polynucleotide encoding the polypeptide and the method for producing the polypeptide by DNA recombinant technology. The invention also discloses the uses of the polypeptide in methods for treating various diseases, such as thyroidal disease, malignant tumor, hemopathy, development disorders, HIV infection, immunological disease, and various inflammation, etc. The invention also discloses the agonists against the polypeptide and the therapeutic action thereof. The invention also discloses the uses of the polynucleotide encoding the human thyroglobuline 9.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AU56054/01A AU5605401A (en) | 2000-03-22 | 2001-03-19 | A novel polypeptide, human thyroglobuline 9 and the polynuceotide encoding the polypeptide |
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN00115018A CN1314377A (en) | 2000-03-22 | 2000-03-22 | New polypeptide-human thyroid globulin 9 and polynucleotide for coding such polypeptide |
| CN00115018.9 | 2000-03-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001075025A2 WO2001075025A2 (en) | 2001-10-11 |
| WO2001075025A3 true WO2001075025A3 (en) | 2002-03-07 |
Family
ID=4584489
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/CN2001/000374 WO2001075025A2 (en) | 2000-03-22 | 2001-03-19 | A novel polypeptide, human thyroglobuline 9 and the polynuceotide encoding the polypeptide |
Country Status (3)
| Country | Link |
|---|---|
| CN (1) | CN1314377A (en) |
| AU (1) | AU5605401A (en) |
| WO (1) | WO2001075025A2 (en) |
-
2000
- 2000-03-22 CN CN00115018A patent/CN1314377A/en active Pending
-
2001
- 2001-03-19 WO PCT/CN2001/000374 patent/WO2001075025A2/en active Application Filing
- 2001-03-19 AU AU56054/01A patent/AU5605401A/en not_active Abandoned
Non-Patent Citations (3)
| Title |
|---|
| CLAVERIE J.M. AND MAKALOWSKI W.: "Alu alert", NATURE, vol. 371, no. 6500, 1994, pages 752 * |
| DI LAURO R. ET AL.: "The sequence of 967 amino acids at the carboxyl-end of rat thyroglobulin. Location and surroundings of two thyroxine-forming sites", EUR. J. BIOCHEM., vol. 148, no. 1, 1985, pages 7 - 11 * |
| KIM P.S. ET AL.: "A single amino acid change in the acetylcholinesterase-like domain of thyroglobulin causes congenital goiter with hypothyroidism in the cog/cog mouse: a model of human endoplasmic reticulum storage diseases", PROC. NATL. ACAD. SCI. USA, vol. 95, no. 17, 1998, pages 9909 - 9913 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1314377A (en) | 2001-09-26 |
| WO2001075025A2 (en) | 2001-10-11 |
| AU5605401A (en) | 2001-10-15 |
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