WO2001070243A3 - A method for treating early breast cancer - Google Patents

A method for treating early breast cancer Download PDF

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Publication number
WO2001070243A3
WO2001070243A3 PCT/US2001/009275 US0109275W WO0170243A3 WO 2001070243 A3 WO2001070243 A3 WO 2001070243A3 US 0109275 W US0109275 W US 0109275W WO 0170243 A3 WO0170243 A3 WO 0170243A3
Authority
WO
WIPO (PCT)
Prior art keywords
breast cancer
treating early
early breast
stem cell
hematopoietic stem
Prior art date
Application number
PCT/US2001/009275
Other languages
French (fr)
Other versions
WO2001070243A2 (en
Inventor
Bonnie J Mills
Original Assignee
Nexell Therapeutics Inc
Bonnie J Mills
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nexell Therapeutics Inc, Bonnie J Mills filed Critical Nexell Therapeutics Inc
Publication of WO2001070243A2 publication Critical patent/WO2001070243A2/en
Publication of WO2001070243A3 publication Critical patent/WO2001070243A3/en

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/18—Growth factors; Growth regulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/28—Compounds containing heavy metals
    • A61K31/282—Platinum compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365—Lactones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/66—Phosphorus compounds
    • A61K31/675—Phosphorus compounds having nitrogen as a ring hetero atom, e.g. pyridoxal phosphate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/28—Bone marrow; Haematopoietic stem cells; Mesenchymal stem cells of any origin, e.g. adipose-derived stem cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/19—Cytokines; Lymphokines; Interferons
    • A61K38/193—Colony stimulating factors [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Methods for treating early stage breast cancer are disclosed. Generally, the methods disclosed use high dose chemotherapy in conjunction with hematopoietic stem cell transplants. Specifically, the methods disclosed use high dose chemotherapy together with selected hematopoietic stem cell transplants.
PCT/US2001/009275 2000-03-23 2001-03-19 A method for treating early breast cancer WO2001070243A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US53355300A 2000-03-23 2000-03-23
US09/533,553 2000-03-23

Publications (2)

Publication Number Publication Date
WO2001070243A2 WO2001070243A2 (en) 2001-09-27
WO2001070243A3 true WO2001070243A3 (en) 2002-02-07

Family

ID=24126463

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/009275 WO2001070243A2 (en) 2000-03-23 2001-03-19 A method for treating early breast cancer

Country Status (1)

Country Link
WO (1) WO2001070243A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2548643A1 (en) * 2003-04-07 2004-10-28 Neostem, Inc. System capable of treating and defining various diseases using stem cells
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
EP2314289A1 (en) 2005-10-31 2011-04-27 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
CA2651813A1 (en) 2006-05-09 2007-11-22 Braincells, Inc. Neurogenesis by modulating angiotensin
US20090197823A1 (en) 2006-05-09 2009-08-06 Braincells, Inc. Aliskiren modulation of neurogenesis
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
RU2554749C1 (en) * 2014-05-30 2015-06-27 Федеральное государственное бюджетное учреждение "Ростовский научно-исследовательский онкологический институт" Министерства здравоохранения Российской Федерации Method of treating early breast cancer

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
CHABANNON C ET AL: "A randomized study of peripheral blood stem cells or isolated CD34 plus cells for hematologic rescue of advanced breast cancer patients treated with high-dose chemotherapy (Meeting abstract).", PROC ANNU MEET AM ASSOC CANCER RES, (1996). VOL. 37, PP. A1207. ISSN: 0197-016X., XP001030934 *
CHABANNON C ET AL: "High-dose chemotherapy followed by reinfusion of selected CD34+ peripheral blood cells in patients with poor-prognosis breast cancer: A randomized multicentre study.", BRITISH JOURNAL OF CANCER, vol. 78, no. 7, October 1998 (1998-10-01), pages 913 - 921, XP001030999, ISSN: 0007-0920 *
DREGER P ET AL: "Autografting of highly purified peripheral blood progenitor cells following myeloablative therapy in patients with lymphoma: A prospective study of the long-term effects on tumor eradication, reconstitution of hematopoiesis and immune recovery.", BONE MARROW TRANSPLANTATION, vol. 24, no. 2, 2 July 1999 (1999-07-02), pages 153 - 161, XP001031101, ISSN: 0268-3369 *
RODENHUIS S ET AL: "Randomised trial of high-dose chemotherapy and haemopoietic progenitor-cell support in operable breast cancer with extensive axillary lymph-node involvement", LANCET, XX, XX, vol. 352, no. 9127, 15 August 1998 (1998-08-15), pages 515 - 521, XP004265525, ISSN: 0140-6736 *
YANOVICH S ET AL: "Transplantation of CD34+ peripheral blood cells selected using a fully automated immunomagnetic system in patients with high-risk breast cancer: Results of a prospective randomized multicenter clinical trial.", BONE MARROW TRANSPLANTATION, vol. 25, no. 11, 1 June 2000 (2000-06-01), pages 1165 - 1174, XP001030994, ISSN: 0268-3369 *

Also Published As

Publication number Publication date
WO2001070243A2 (en) 2001-09-27

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