WO2001068701A3 - Regulation of human seven transmembrane - like g protein - coupled receptor (7tm-gpcr) - Google Patents

Regulation of human seven transmembrane - like g protein - coupled receptor (7tm-gpcr) Download PDF

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Publication number
WO2001068701A3
WO2001068701A3 PCT/EP2001/002978 EP0102978W WO0168701A3 WO 2001068701 A3 WO2001068701 A3 WO 2001068701A3 EP 0102978 W EP0102978 W EP 0102978W WO 0168701 A3 WO0168701 A3 WO 0168701A3
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WO
WIPO (PCT)
Prior art keywords
protein
gpcr
human
transmembrane
coupled receptor
Prior art date
Application number
PCT/EP2001/002978
Other languages
French (fr)
Other versions
WO2001068701A2 (en
Inventor
Shyam Ramakrishnan
Original Assignee
Bayer Ag
Shyam Ramakrishnan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer Ag, Shyam Ramakrishnan filed Critical Bayer Ag
Priority to EP01915356A priority Critical patent/EP1265923A2/en
Priority to AU2001242474A priority patent/AU2001242474A1/en
Publication of WO2001068701A2 publication Critical patent/WO2001068701A2/en
Publication of WO2001068701A3 publication Critical patent/WO2001068701A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

Reagents which regulate human seven transmembrane-like G protein-coupled receptor (7TM-GPCR) protein and reagents which bind to human 7TM-GPCR gene products can play a role in preventing, ameliorating, or correcting dysfunctions or diseases including, but not limited to, infections such as bacterial, fungal, protozoan, and viral infections, particularly those caused by HIV viruses, pain, cancers, anorexia, bulimia, asthma, Parkinson's diseases, acute heart failure, hypotension, hypertension, urinary retention, osteoporosis, angina pectoris, myocardial infarction, ulcers, asthma, allergies, multiple sclerosis, benign prostatic hypertrophy, and psychotic and neurological disorders, including anxiety, schizophrenia, manic depression, delirium, dementia, several mental retardation, and dyskinesias, such as Huntington's disease and Tourett's syndrome.
PCT/EP2001/002978 2000-03-16 2001-03-15 Regulation of human seven transmembrane - like g protein - coupled receptor (7tm-gpcr) WO2001068701A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP01915356A EP1265923A2 (en) 2000-03-16 2001-03-15 Regulation of human seven transmembrane-like g protein-coupled receptor (7tm-gpcr)
AU2001242474A AU2001242474A1 (en) 2000-03-16 2001-03-15 Regulation of human seven transmembrane-like g protein-coupled receptor

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18987600P 2000-03-16 2000-03-16
US60/189,876 2000-03-16

Publications (2)

Publication Number Publication Date
WO2001068701A2 WO2001068701A2 (en) 2001-09-20
WO2001068701A3 true WO2001068701A3 (en) 2002-03-21

Family

ID=22699129

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2001/002978 WO2001068701A2 (en) 2000-03-16 2001-03-15 Regulation of human seven transmembrane - like g protein - coupled receptor (7tm-gpcr)

Country Status (3)

Country Link
EP (1) EP1265923A2 (en)
AU (1) AU2001242474A1 (en)
WO (1) WO2001068701A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001094417A2 (en) * 2000-06-09 2001-12-13 Lexicon Genetics Incorporated Novel human seven transmembrane proteins and polynucleotides encoding the same
US20030143668A1 (en) * 2001-06-18 2003-07-31 National Institute Of Advanced Industrial Guanosine triphosphate-binding protein coupled receptors

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0807684A1 (en) * 1996-05-16 1997-11-19 Takeda Chemical Industries, Ltd. Human G-protein coupled receptor (HIBCD07)
WO2000061623A1 (en) * 1999-04-09 2000-10-19 Human Genome Sciences, Inc. 62 human secreted proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0807684A1 (en) * 1996-05-16 1997-11-19 Takeda Chemical Industries, Ltd. Human G-protein coupled receptor (HIBCD07)
WO2000061623A1 (en) * 1999-04-09 2000-10-19 Human Genome Sciences, Inc. 62 human secreted proteins

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
ABE J ET AL: "IG-HEPTA, A NOVEL MEMBER OF THE G PROTEIN-COUPLED HEPTA-HELICAL RECEPTOR (GPCR) FAMILY THAT HAS IMMUNOGLOBULIN-LIKE REPEATS IN A LONG N-TERMINAL EXTRACELLULAR DOMAIN AND DEFINES A NEW SUBFAMILY OFGPCRS", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 274, no. 28, 1999, pages 19957 - 19964, XP002925400, ISSN: 0021-9258 *
COMBADIERE C ET AL: "CLONING AND FUNCTIONAL EXPRESSION OF A HUMAN EOSINOPHIL CC CHEMOKINE RECEPTOR", JOURNAL OF BIOLOGICAL CHEMISTRY, AMERICAN SOCIETY OF BIOLOGICAL CHEMISTS, BALTIMORE, MD, US, vol. 270, no. 27, 14 July 1995 (1995-07-14), pages 16491 - 16494, XP001018021, ISSN: 0021-9258 *
HINUMA S ET AL: "A prolactin -releasing peptide in the brain", NATURE, MACMILLAN JOURNALS LTD. LONDON, GB, vol. 393, no. 6682, 21 May 1998 (1998-05-21), pages 272 - 276, XP002084793, ISSN: 0028-0836 *

Also Published As

Publication number Publication date
AU2001242474A1 (en) 2001-09-24
EP1265923A2 (en) 2002-12-18
WO2001068701A2 (en) 2001-09-20

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