WO2001064905A3 - 2504, 15977, and 14760, novel protein kinase family members and uses therefor - Google Patents

2504, 15977, and 14760, novel protein kinase family members and uses therefor Download PDF

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Publication number
WO2001064905A3
WO2001064905A3 PCT/US2001/006525 US0106525W WO0164905A3 WO 2001064905 A3 WO2001064905 A3 WO 2001064905A3 US 0106525 W US0106525 W US 0106525W WO 0164905 A3 WO0164905 A3 WO 0164905A3
Authority
WO
WIPO (PCT)
Prior art keywords
protein kinase
family members
kinase family
novel protein
molecules
Prior art date
Application number
PCT/US2001/006525
Other languages
French (fr)
Other versions
WO2001064905A2 (en
Inventor
Peter J Olandt
Rosana Kapeller-Libermann
Rachel E Meyers
Original Assignee
Millennium Pharm Inc
Peter J Olandt
Rosana Kapeller-Libermann
Rachel E Meyers
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Millennium Pharm Inc, Peter J Olandt, Rosana Kapeller-Libermann, Rachel E Meyers filed Critical Millennium Pharm Inc
Priority to AU2001241880A priority Critical patent/AU2001241880A1/en
Priority to EP01913192A priority patent/EP1259620A2/en
Publication of WO2001064905A2 publication Critical patent/WO2001064905A2/en
Priority to US10/170,789 priority patent/US7070947B2/en
Publication of WO2001064905A3 publication Critical patent/WO2001064905A3/en
Priority to US11/151,601 priority patent/US7198930B2/en
Priority to US11/636,948 priority patent/US7282360B2/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1205—Phosphotransferases with an alcohol group as acceptor (2.7.1), e.g. protein kinases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention provides isolated nucleic acids molecules, designated 2504, 15977, or 14760 nucleic acid molecules, which encode novel protein kinase family members. The invention also provides antisense nucleic acid molecules, recombinant expression vectors containing 2504, 15977, or 14760 nucleic molecules, host cells into which the expression vectors have been introduced, and nonhuman transgenic animals in which a 2504, 15977, or 14760 gene has been introduced or disrupted. The invention still further provides isolated 2504, 15977, or 14760 proteins, fusion proteins, antigenic peptides and anti-2504, 15977, or 14760 antibodies. Diagnostic methods utilizing compositions of the invention are also provided.
PCT/US2001/006525 2000-02-29 2001-02-28 2504, 15977, and 14760, novel protein kinase family members and uses therefor WO2001064905A2 (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
AU2001241880A AU2001241880A1 (en) 2000-02-29 2001-02-28 2504, 15977, and 14760, novel protein kinase family members and uses therefor
EP01913192A EP1259620A2 (en) 2000-02-29 2001-02-28 2504, 15977, and 14760, novel protein kinase family members and uses therefor
US10/170,789 US7070947B2 (en) 2000-02-29 2002-06-13 Human protein kinase, phosphatase, and protease family members and uses thereof
US11/151,601 US7198930B2 (en) 2000-02-29 2005-06-13 Human protein kinase, phosphatase, and protease family members and uses thereof
US11/636,948 US7282360B2 (en) 2000-02-29 2006-12-11 Human protein kinase, phosphatase, and protease family members and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18606100P 2000-02-29 2000-02-29
US60/186,061 2000-02-29

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US10/170,789 Continuation-In-Part US7070947B2 (en) 2000-02-29 2002-06-13 Human protein kinase, phosphatase, and protease family members and uses thereof

Publications (2)

Publication Number Publication Date
WO2001064905A2 WO2001064905A2 (en) 2001-09-07
WO2001064905A3 true WO2001064905A3 (en) 2002-08-08

Family

ID=22683502

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/006525 WO2001064905A2 (en) 2000-02-29 2001-02-28 2504, 15977, and 14760, novel protein kinase family members and uses therefor

Country Status (4)

Country Link
US (1) US6730491B2 (en)
EP (1) EP1259620A2 (en)
AU (1) AU2001241880A1 (en)
WO (1) WO2001064905A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2001088135A2 (en) * 2000-05-15 2001-11-22 Curagen Corporation G-protein coupled receptor proteins and nucleic acids encoding same
US6461846B2 (en) * 2000-05-30 2002-10-08 Pe Corporation Isolated human kinase proteins, nucleic acid molecules encoding human kinase proteins, and uses thereof
WO2002024889A2 (en) * 2000-09-12 2002-03-28 The Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services Optimized cardiac contraction through differential phosphorylation of myosin
WO2015066027A2 (en) 2013-10-28 2015-05-07 Dots Devices, Inc. Allergen detection

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999027080A2 (en) * 1997-11-25 1999-06-03 Incyte Pharmaceuticals, Inc. Human protein kinase and kinase inhibitors
WO2000055177A2 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. 49 human secreted proteins
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'
WO2001012659A2 (en) * 1999-08-18 2001-02-22 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Human dna sequences
WO2001020004A2 (en) * 1999-09-15 2001-03-22 Incyte Genomics, Inc. Protein phosphatase and kinase proteins
EP1130094A2 (en) * 1999-07-08 2001-09-05 Helix Research Institute Primers for synthesizing full length cDNA clones and their use
WO2001081555A2 (en) * 2000-04-20 2001-11-01 Incyte Genomics, Inc. Human kinases

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6060296A (en) * 1991-07-03 2000-05-09 The Salk Institute For Biological Studies Protein kinases
US6331424B1 (en) * 1999-04-20 2001-12-18 Cytokinetics, Inc. Motor proteins and methods for their use
AU7899100A (en) 1999-10-18 2001-04-30 Shanghai Bio Road Gene Development Ltd. A novel polypeptide, a human casein kinase 48 and the polynucleotide encoding the polypeptide
AU784540B2 (en) 2000-01-18 2006-04-27 Lexicon Pharmaceuticals, Inc. Novel human kinase protein and polynucleotides encoding the same

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999027080A2 (en) * 1997-11-25 1999-06-03 Incyte Pharmaceuticals, Inc. Human protein kinase and kinase inhibitors
WO2000055177A2 (en) * 1999-03-12 2000-09-21 Human Genome Sciences, Inc. 49 human secreted proteins
WO2000058473A2 (en) * 1999-03-31 2000-10-05 Curagen Corporation Nucleic acids including open reading frames encoding polypeptides; 'orfx'
EP1130094A2 (en) * 1999-07-08 2001-09-05 Helix Research Institute Primers for synthesizing full length cDNA clones and their use
WO2001012659A2 (en) * 1999-08-18 2001-02-22 Fraunhofer-Gesellschaft Zur Foerderung Der Angewandten Forschung E.V. Human dna sequences
WO2001020004A2 (en) * 1999-09-15 2001-03-22 Incyte Genomics, Inc. Protein phosphatase and kinase proteins
WO2001081555A2 (en) * 2000-04-20 2001-11-01 Incyte Genomics, Inc. Human kinases

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
DATABASE EM_MUS 19 October 1999 (1999-10-19), "Mus musculus brain cDNA, clone:MNCb-4360, 5' end", XP002187601 *
DATABASE EM_PAT 9 March 2001 (2001-03-09), "Sequence 230 from WO0112659", XP002187603 *
DATABASE EM_RO 21 November 1993 (1993-11-21), "Rattus norvegicus vesicla-associate calmodulin-binding protein", XP002187600 *
DATABASE EPOP 6 March 2001 (2001-03-06), "Sequence 231 from WO0112659", XP002187678 *
DATABASE EPOP 6 March 2001 (2001-03-06), "Sequence 232 from WO0112659", XP002187679 *
DATABASE EPOP 6 March 2001 (2001-03-06), "Sequence 233 from WO0112659", XP002187680 *
DATABASE GSP 6 November 2001 (2001-11-06), "SEQ ID 2957 from EP1130094", XP002187604 *
DATABASE GSP 6 November 2001 (2001-11-06), "SEQ ID 3008 from EP1130094", XP002187605 *
DATABASE GSP 6 November 2001 (2001-11-06), "SEQ ID 3572 from EP1130094", XP002187606 *
DATABASE SWALL 1 May 1999 (1999-05-01), "Calmodulin binding protein kinase", XP002187602 *

Also Published As

Publication number Publication date
WO2001064905A2 (en) 2001-09-07
AU2001241880A1 (en) 2001-09-12
US6730491B2 (en) 2004-05-04
US20020042099A1 (en) 2002-04-11
EP1259620A2 (en) 2002-11-27

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