WO2001064227A3 - Androgenic activity of eucommia ulmoides extracts - Google Patents

Androgenic activity of eucommia ulmoides extracts Download PDF

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Publication number
WO2001064227A3
WO2001064227A3 PCT/SG2001/000038 SG0100038W WO0164227A3 WO 2001064227 A3 WO2001064227 A3 WO 2001064227A3 SG 0100038 W SG0100038 W SG 0100038W WO 0164227 A3 WO0164227 A3 WO 0164227A3
Authority
WO
WIPO (PCT)
Prior art keywords
present
composition
eucommia ulmoides
modulating
androgenic activity
Prior art date
Application number
PCT/SG2001/000038
Other languages
French (fr)
Other versions
WO2001064227A2 (en
Inventor
Yek Cheng Ong
Eu Leong Yong
Original Assignee
Univ Singapore
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Singapore filed Critical Univ Singapore
Priority to AU42993/01A priority Critical patent/AU4299301A/en
Publication of WO2001064227A2 publication Critical patent/WO2001064227A2/en
Publication of WO2001064227A3 publication Critical patent/WO2001064227A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/46—Eucommiaceae (Eucommia family), e.g. hardy rubber tree
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/24—Drugs for disorders of the endocrine system of the sex hormones
    • A61P5/26—Androgens
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/81—Packaged device or kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Endocrinology (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Organic Chemistry (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Epidemiology (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

The present invention relates generally to a method for modulating steroidogenic activity and a composition useful for same. The present invention further relates to a composition comprising a steroidogenic modulator useful for modulating physiological processes mediated by the androgen receptor or an active form thereof or complex comprising same and/or for modulating physiological processes mediated by estrogen receptors. The composition of the present invention preferably comprises an extract of herbs or botanical or horticultural equivalents of the herbs or chemical or functional equivalents of one or more components of the herbal extract thereof.
PCT/SG2001/000038 2000-02-29 2001-02-27 Androgenic activity of eucommia ulmoides extracts WO2001064227A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU42993/01A AU4299301A (en) 2000-02-29 2001-02-27 A method for modulating steroidogenic activity

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US18575700P 2000-02-29 2000-02-29
US60/185,757 2000-02-29

Publications (2)

Publication Number Publication Date
WO2001064227A2 WO2001064227A2 (en) 2001-09-07
WO2001064227A3 true WO2001064227A3 (en) 2002-04-04

Family

ID=22682344

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/SG2001/000038 WO2001064227A2 (en) 2000-02-29 2001-02-27 Androgenic activity of eucommia ulmoides extracts

Country Status (3)

Country Link
US (2) US6905714B2 (en)
AU (1) AU4299301A (en)
WO (1) WO2001064227A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7132117B2 (en) * 2000-08-29 2006-11-07 Government Of Malaysia Bioactive fraction of Eurycoma longifolia
US7524518B2 (en) * 2001-05-11 2009-04-28 Kim Sung-Jin Composition for promoting regeneration of hard tissues comprising an extract of cortex eucommiae
TWI221154B (en) * 2001-09-12 2004-09-21 Akzo Nobel Nv 17alpha-hydroxy-14beta-steroids with hormonal effect
US7381432B2 (en) * 2006-09-19 2008-06-03 Jose Angel Olalde Menopause disorder synergistic phyto-nutraceutical composition
JP2009091276A (en) * 2007-10-05 2009-04-30 Pola Chem Ind Inc Composition for bone ageing inhibition
US7893399B2 (en) * 2008-09-09 2011-02-22 Quest Diagnostics Investments Incorporated Methods for detecting dehydroepiandrosterone by mass spectrometry
US7804063B2 (en) * 2008-10-06 2010-09-28 Quest Diagnostics Investments Incorporated Methods for detecting dihydrotestosterone by mass spectrometry
CN102885726A (en) * 2011-07-19 2013-01-23 上海家化联合股份有限公司 Eucommia extract product, its preparation method and application thereof
CN104391072B (en) * 2014-11-12 2016-08-17 广州白云山敬修堂药业股份有限公司 A kind of detection method of the compound Chinese medicinal preparation treating osteoporosis
US11058737B2 (en) * 2018-10-29 2021-07-13 Biotropics Malaysia Berhad Use of Euycoma longifolia extract in alleviating symptoms and/or conditions associated with hormonal imbalance in females
CN111804004B (en) * 2020-08-03 2021-07-20 于瀛 Extraction and leaching method of traditional Chinese medicine

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04169536A (en) * 1990-10-30 1992-06-17 Morishita Jintan Kk Therapeutic agent for osteoporosis

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04187623A (en) * 1990-11-22 1992-07-06 Pola Chem Ind Inc Hair cosmetics
JPH05268921A (en) * 1992-03-25 1993-10-19 Hitachi Zosen Corp Blend of 'tochu' tea with roast tea
US6017924A (en) * 1996-06-27 2000-01-25 Ligand Pharmaceuticals Incorporated Androgen receptor modulator compounds and methods

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH04169536A (en) * 1990-10-30 1992-06-17 Morishita Jintan Kk Therapeutic agent for osteoporosis

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
BIOLOGICAL & PHARMACEUTICAL BULLETIN, vol. 17, no. 7, 1994, pages 917 - 920, ISSN: 0918-6158 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1994, METORI KOICHI ET AL: "Effects of Du-Zhong leaf extract on serum and hepatic lipids in rats fed a high-fat diet.", XP002184764, Database accession no. PREV199598097079 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1997, QU GANG-JIAN ET AL: "Anabolic effects of Tu-Chung extract. Studies using castrated rat.", XP002184762, Database accession no. PREV199799662861 *
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; August 1999 (1999-08-01), QU GANG-JIAN ET AL: "Effects of Tu-Chung extract administrating on serum testosterone in hindlimb-suspended rats.", XP002184763, Database accession no. PREV200000057941 *
JAPANESE JOURNAL OF PHYSICAL FITNESS AND SPORTS MEDICINE, vol. 46, no. 3, 1997, pages 263 - 272, ISSN: 0039-906X *
PATENT ABSTRACTS OF JAPAN vol. 016, no. 470 (C - 0990) 30 September 1992 (1992-09-30) *
TAIRYOKU KAGAKU, vol. 48, no. 4, August 1999 (1999-08-01), pages 501 - 508, ISSN: 0039-906X *

Also Published As

Publication number Publication date
AU4299301A (en) 2001-09-12
US20050123634A1 (en) 2005-06-09
WO2001064227A2 (en) 2001-09-07
US20010046524A1 (en) 2001-11-29
US6905714B2 (en) 2005-06-14

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