WO2001064030A1 - Implantation - Google Patents
Implantation Download PDFInfo
- Publication number
- WO2001064030A1 WO2001064030A1 PCT/IB2001/000283 IB0100283W WO0164030A1 WO 2001064030 A1 WO2001064030 A1 WO 2001064030A1 IB 0100283 W IB0100283 W IB 0100283W WO 0164030 A1 WO0164030 A1 WO 0164030A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- artefact
- implant
- anchor
- bioactive material
- subject
- Prior art date
Links
- 238000002513 implantation Methods 0.000 title claims abstract description 14
- 239000007943 implant Substances 0.000 claims abstract description 40
- 230000000975 bioactive effect Effects 0.000 claims abstract description 31
- 239000000463 material Substances 0.000 claims abstract description 31
- 210000004872 soft tissue Anatomy 0.000 claims abstract description 18
- 238000013508 migration Methods 0.000 claims abstract description 10
- 230000005012 migration Effects 0.000 claims abstract description 9
- 230000002401 inhibitory effect Effects 0.000 claims abstract description 5
- 238000000034 method Methods 0.000 claims description 9
- 238000004873 anchoring Methods 0.000 claims description 8
- 239000002775 capsule Substances 0.000 claims description 8
- 239000002344 surface layer Substances 0.000 claims description 6
- 239000002131 composite material Substances 0.000 claims description 4
- 229910019142 PO4 Inorganic materials 0.000 claims description 3
- 239000001506 calcium phosphate Substances 0.000 claims description 3
- 239000011248 coating agent Substances 0.000 claims description 3
- 238000000576 coating method Methods 0.000 claims description 3
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 3
- 239000000560 biocompatible material Substances 0.000 claims description 2
- 235000011010 calcium phosphates Nutrition 0.000 claims description 2
- 239000004568 cement Substances 0.000 claims description 2
- 239000000919 ceramic Substances 0.000 claims description 2
- 238000010276 construction Methods 0.000 claims description 2
- 239000011521 glass Substances 0.000 claims description 2
- 239000002241 glass-ceramic Substances 0.000 claims description 2
- 239000010452 phosphate Substances 0.000 claims description 2
- 229910000389 calcium phosphate Inorganic materials 0.000 claims 1
- 210000001519 tissue Anatomy 0.000 description 9
- 241001465754 Metazoa Species 0.000 description 4
- 229920000249 biocompatible polymer Polymers 0.000 description 4
- 229910052588 hydroxylapatite Inorganic materials 0.000 description 4
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 description 4
- 230000015572 biosynthetic process Effects 0.000 description 3
- 238000005755 formation reaction Methods 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 229920000642 polymer Polymers 0.000 description 2
- 230000002035 prolonged effect Effects 0.000 description 2
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 1
- 239000004698 Polyethylene Substances 0.000 description 1
- 230000003592 biomimetic effect Effects 0.000 description 1
- 239000002639 bone cement Substances 0.000 description 1
- 229910052791 calcium Inorganic materials 0.000 description 1
- 239000011575 calcium Substances 0.000 description 1
- 150000004649 carbonic acid derivatives Chemical class 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 238000010285 flame spraying Methods 0.000 description 1
- 239000003550 marker Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 235000021317 phosphate Nutrition 0.000 description 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 description 1
- 238000007750 plasma spraying Methods 0.000 description 1
- -1 polyethylene Polymers 0.000 description 1
- 229920000573 polyethylene Polymers 0.000 description 1
- 239000000941 radioactive substance Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 1
- 235000019731 tricalcium phosphate Nutrition 0.000 description 1
- 229940078499 tricalcium phosphate Drugs 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K11/00—Marking of animals
- A01K11/006—Automatic identification systems for animals, e.g. electronic devices, transponders for animals
Definitions
- THIS INVENTION relates to implantation. In particular, it relates to
- identification tags for implantation in animals. While the medical implants and
- identification tags may be tolerated in a body, body cells do not neccessarily
- the implanted object is
- implanted objects is to provide the implanted objects with anti-migration formations.
- this approach is not always successful, particularly if it is
- an artefact suitable for body implantation including
- anchor means associated with the implant, for inhibiting
- the anchor means comprising
- bioactive material is intended to be any substance that is intended to be any substance.
- suitable bioactive materials are ceramics and cements
- composite materials which include at least one bioactive component or material
- biocompatible material such as hydroxyapatite- polyethylene composites.
- the bioactive component of such a composite material may define exposed bioactive surface sites.
- the bioactive material of the anchor means may be porous.
- porous bioactive material may have micropores up to about 1 00 ⁇ m in size
- the anchor means is in the form
- the anchor body may be attached to the implant.
- the anchor body may be attached to the implant.
- the implant by mechanical means, adhesive means, or the like and may be of
- the artefact may include attachment means attaching
- the anchor means is in the
- capsule may be configured to allow the implant to resorb or release components
- capsule may have an aperture through which the implant can be inserted.
- the capsule may include closure means for the aperture.
- the closure means may be of a biocompatible polymer, e.g. in the form of a plug of a biocompatible
- the anchor means is in the
- a coating of a bioactive material which covers at least part of the implant.
- a coating can for example be applied to the implant by flame or plasma spraying, or by biomimetic means.
- the anchor means is in
- a cast body of a settable bioactive material such as a bone cement
- the anchor means is
- implant e.g. where the implant is a flexible biocompatible polymer or has an outer
- the anchor means may also comprise a converted surface layer of
- the implant with the converted surface layer thus being of bioactive material
- the remainder of the implant being of unconverted material or a non-bioactive
- the converted surface layer may be that obtained by treating material
- the surface layer of the implant may be effected by chemical, thermal or other
- the anchor body may define a circular outline for the artefact in at
- the artefact may be generally elongate and the anchor body may be cylindrical, e.g . circular cylindrical.
- the implant may be an animal marker, e.g. a transponder. Instead,
- the implant may be a sensor for sensing one or more body conditions.
- implants which can be positioned and anchored by means of the
- artefact of the invention include a pharmaceutical substance, a body of living cells, and a radioactive substance.
- the anchor body may be adapted to inhibit migration of the artefact
- the anchor body may define anchoring formations such as recesses, apertures, slots,
- a method of anchoring an artefact in the body of a subject including
- tissue of the body of the subject and allowing soft tissue of the body to attach to and form a bond with the
- anchor means of the artefact thereby to anchor the artefact in the body in the
- the method may include temporarily anchoring the artefact in the
- the artefact may include temporarily suturing the artefact in place, e.g. with a
- artefact may be inserted surgically by making an incision in the soft tissue.
- Figure 1 shows a three dimensional view of one embodiment of an artefact
- Figure 2 shows a three dimensional view of another embodiment of an
- Figure 3 shows a longitudinally sectioned view of yet another embodiment
- reference numeral 10 generally indicates an artefact in accordance with the invention suitable for body implantation.
- the artefact 10 includes an implant, in the form of an elongate
- the transponder 1 2 is a conventional transponder used for marking an animal.
- the artefact 10 also includes anchor means, in the form of an anchor
- the anchor body 1 4 of hydroxyapatite.
- the anchor body 1 4 defines an essentially cylindrical
- a plurality of anchoring formations, in the form of recesses 20 is
- the transponder 1 2 is located inside the passage 1 8 and is
- the artefact 1 0 is circular cylindrical in outline, having
- the artefact 1 0 is placed in a desired location in the soft
- tissue of a subject such as an animal, by means of a syringe.
- outer surface 1 6 of the anchor body 1 4 serves to limit movement of the anchor
- the anchor body 14 being of hydroxyapatite and thus bioactive, allows
- the artefact 30 is similar to the artefact 1 0, and unless otherwise indicated,
- the artefact 30 has an
- anchor body 32 which is longitudinally spaced from the transponder 1 2 and
- attachment means in the form of a
- Two passages 36, 38 extend through the anchor body 32.
- the artefact 30 is typically inserted surgically by making an incision in the soft tissue of the body of a subject , and locating the artefact 30
- the passages 36, 38 can be used to suture the
- the suturing is typically done using a suture which degrades or resorbs over time, so that eventually the artefact 30 is anchored in place by the soft tissue of
- reference numeral 40 generally
- artefact 40 is similar to the artefact
- the artefact 40 has an anchor body 42 which is in the form of a
- the anchor body 42 is shaped and dimensioned to receive the
- transponder 1 2 fully and with a snug fit.
- the anchor body 42 is used to assemble the artefact 40, whereafter the plug 44
- the anchor body 42 also has a circular cylindrical outer surface 1 6
- anchor means of a bioactive material allowing soft tissue of a living
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Environmental Sciences (AREA)
- Birds (AREA)
- Zoology (AREA)
- Animal Husbandry (AREA)
- Biodiversity & Conservation Biology (AREA)
- Prostheses (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU2001235899A AU2001235899A1 (en) | 2000-03-02 | 2001-03-01 | Implantation |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ZA200001067 | 2000-03-02 | ||
ZA2000/1067 | 2000-03-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO2001064030A1 true WO2001064030A1 (fr) | 2001-09-07 |
Family
ID=25588650
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB2001/000283 WO2001064030A1 (fr) | 2000-03-02 | 2001-03-01 | Implantation |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU2001235899A1 (fr) |
WO (1) | WO2001064030A1 (fr) |
Cited By (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002052929A3 (fr) * | 2001-01-04 | 2002-11-14 | Ustherapeutics L L C | Systeme implante pour la localisation et la surveillance d'animaux |
US7910124B2 (en) | 2004-02-06 | 2011-03-22 | Georgia Tech Research Corporation | Load bearing biocompatible device |
US8002830B2 (en) | 2004-02-06 | 2011-08-23 | Georgia Tech Research Corporation | Surface directed cellular attachment |
FR2961605A1 (fr) * | 2010-06-18 | 2011-12-23 | Univ Sud Toulon Var | Balise satellite pour le suivi des baleines |
US9155543B2 (en) | 2011-05-26 | 2015-10-13 | Cartiva, Inc. | Tapered joint implant and related tools |
US9907663B2 (en) | 2015-03-31 | 2018-03-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
US10350072B2 (en) | 2012-05-24 | 2019-07-16 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
US10758374B2 (en) | 2015-03-31 | 2020-09-01 | Cartiva, Inc. | Carpometacarpal (CMC) implants and methods |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0480530A1 (fr) * | 1990-10-09 | 1992-04-15 | Texas Instruments Incorporated | Réspondeur et procédé pour sa production |
WO1993011661A1 (fr) * | 1991-12-11 | 1993-06-24 | Ragnar Winberg | Dispositif de marquage d'animaux |
DE29616618U1 (de) * | 1996-09-24 | 1996-11-28 | Ulrich, Martin, 90409 Nürnberg | Fixierhilfe zur Unterdrückung der Migration von Transpondern bei der Implantation in Tierkörper |
-
2001
- 2001-03-01 AU AU2001235899A patent/AU2001235899A1/en not_active Abandoned
- 2001-03-01 WO PCT/IB2001/000283 patent/WO2001064030A1/fr active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0480530A1 (fr) * | 1990-10-09 | 1992-04-15 | Texas Instruments Incorporated | Réspondeur et procédé pour sa production |
WO1993011661A1 (fr) * | 1991-12-11 | 1993-06-24 | Ragnar Winberg | Dispositif de marquage d'animaux |
DE29616618U1 (de) * | 1996-09-24 | 1996-11-28 | Ulrich, Martin, 90409 Nürnberg | Fixierhilfe zur Unterdrückung der Migration von Transpondern bei der Implantation in Tierkörper |
Cited By (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2002052929A3 (fr) * | 2001-01-04 | 2002-11-14 | Ustherapeutics L L C | Systeme implante pour la localisation et la surveillance d'animaux |
US7910124B2 (en) | 2004-02-06 | 2011-03-22 | Georgia Tech Research Corporation | Load bearing biocompatible device |
US8002830B2 (en) | 2004-02-06 | 2011-08-23 | Georgia Tech Research Corporation | Surface directed cellular attachment |
US8486436B2 (en) | 2004-02-06 | 2013-07-16 | Georgia Tech Research Corporation | Articular joint implant |
US8895073B2 (en) | 2004-02-06 | 2014-11-25 | Georgia Tech Research Corporation | Hydrogel implant with superficial pores |
FR2961605A1 (fr) * | 2010-06-18 | 2011-12-23 | Univ Sud Toulon Var | Balise satellite pour le suivi des baleines |
US10376368B2 (en) | 2011-05-26 | 2019-08-13 | Cartiva, Inc. | Devices and methods for creating wedge-shaped recesses |
US9526632B2 (en) | 2011-05-26 | 2016-12-27 | Cartiva, Inc. | Methods of repairing a joint using a wedge-shaped implant |
US11944545B2 (en) | 2011-05-26 | 2024-04-02 | Cartiva, Inc. | Implant introducer |
US9155543B2 (en) | 2011-05-26 | 2015-10-13 | Cartiva, Inc. | Tapered joint implant and related tools |
US11278411B2 (en) | 2011-05-26 | 2022-03-22 | Cartiva, Inc. | Devices and methods for creating wedge-shaped recesses |
US10350072B2 (en) | 2012-05-24 | 2019-07-16 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
US10973644B2 (en) | 2015-03-31 | 2021-04-13 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
US10758374B2 (en) | 2015-03-31 | 2020-09-01 | Cartiva, Inc. | Carpometacarpal (CMC) implants and methods |
US11717411B2 (en) | 2015-03-31 | 2023-08-08 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
US11839552B2 (en) | 2015-03-31 | 2023-12-12 | Cartiva, Inc. | Carpometacarpal (CMC) implants and methods |
US9907663B2 (en) | 2015-03-31 | 2018-03-06 | Cartiva, Inc. | Hydrogel implants with porous materials and methods |
US10952858B2 (en) | 2015-04-14 | 2021-03-23 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
US11020231B2 (en) | 2015-04-14 | 2021-06-01 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
US11701231B2 (en) | 2015-04-14 | 2023-07-18 | Cartiva, Inc. | Tooling for creating tapered opening in tissue and related methods |
Also Published As
Publication number | Publication date |
---|---|
AU2001235899A1 (en) | 2001-09-12 |
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