WO2001049246A3 - Sustained release tablet formulations comprising clarithromycin - Google Patents

Sustained release tablet formulations comprising clarithromycin

Info

Publication number
WO2001049246A3
WO2001049246A3 PCT/TR2001/000002 TR0100002W WO0149246A3 WO 2001049246 A3 WO2001049246 A3 WO 2001049246A3 TR 0100002 W TR0100002 W TR 0100002W WO 0149246 A3 WO0149246 A3 WO 0149246A3
Authority
WO
Grant status
Application
Patent type
Prior art keywords
clarithromycin
sustained release
release
release tablet
tablet formulations
Prior art date
Application number
PCT/TR2001/000002
Other languages
French (fr)
Other versions
WO2001049246A2 (en )
Inventor
Levent Oener
Ahmet Toksoez
Original Assignee
Sanovel Lac Sanay Ve T Caret A
Levent Oener
Ahmet Toksoez
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin digitoxin or digoxin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/205Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose

Abstract

This invention covers the sustained release tablets containing hydroxypropylmethylcellulose as matrix material and clarithromycin as active ingredient. Clarithromycin is released from sustained release tablet with a rate expressed by the equation Mt/M =ktn. In this equation n is the exponent of the release kinetics and n value determines the type of release mechanism. When n value is between 0.89 to 1, release rate complies with zero-order kinetic and it is independent from time.
PCT/TR2001/000002 2000-01-05 2001-01-04 Sustained release tablet formulations comprising clarithromycin WO2001049246A3 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
TR200000054 2000-01-05
TR2000/00054 2000-01-05

Publications (2)

Publication Number Publication Date
WO2001049246A2 true WO2001049246A2 (en) 2001-07-12
WO2001049246A3 true true WO2001049246A3 (en) 2002-08-15

Family

ID=21622322

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/TR2001/000002 WO2001049246A3 (en) 2000-01-05 2001-01-04 Sustained release tablet formulations comprising clarithromycin

Country Status (1)

Country Link
WO (1) WO2001049246A3 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1285659B1 (en) * 2001-08-13 2007-06-27 Fondazione Salvatore Maugeri - Clinica del Lavoro e della Riabilitazione Use of clarithromycin compositions in the manufacture of a medicament for the treatment of arthritis deformans
US6642276B2 (en) * 2001-10-01 2003-11-04 M/S Ind-Swift Limited Controlled release macrolide pharmaceutical formulations
EP1720524A2 (en) * 2004-02-26 2006-11-15 Ranbaxy Laboratories Limited Extended release tablets of clarithromycin
EP2283824B1 (en) 2009-07-30 2017-04-19 Special Products Line S.p.A. Compositions and formulations based on swellable matrices for sustained release of poorly soluble drugs such as clarithromycin

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0967256A (en) * 1995-08-31 1997-03-11 Taisho Pharmaceut Co Ltd Drug for common cold
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
US6010718A (en) * 1997-04-11 2000-01-04 Abbott Laboratories Extended release formulations of erythromycin derivatives
WO2000048607A1 (en) * 1999-02-19 2000-08-24 LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. Directly compressible matrix for controlled release of single daily doses of clarithromycin

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0967256A (en) * 1995-08-31 1997-03-11 Taisho Pharmaceut Co Ltd Drug for common cold
US5705190A (en) * 1995-12-19 1998-01-06 Abbott Laboratories Controlled release formulation for poorly soluble basic drugs
US6010718A (en) * 1997-04-11 2000-01-04 Abbott Laboratories Extended release formulations of erythromycin derivatives
WO2000048607A1 (en) * 1999-02-19 2000-08-24 LEK, tovarna farmacevtskih in kemičnih izdelkov, d.d. Directly compressible matrix for controlled release of single daily doses of clarithromycin

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
DATABASE WPI Week 9720, Derwent World Patents Index; AN 1997-221692, XP002176786, "Remedies for colds- comprise ibuprofen and/or acetaminophen and clarithromycin" *

Also Published As

Publication number Publication date Type
WO2001049246A2 (en) 2001-07-12 application

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