WO2001042466A3 - Zvwf1: a member of the von willebrand factor type a domain superfamily - Google Patents

Zvwf1: a member of the von willebrand factor type a domain superfamily Download PDF

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Publication number
WO2001042466A3
WO2001042466A3 PCT/US2000/033161 US0033161W WO0142466A3 WO 2001042466 A3 WO2001042466 A3 WO 2001042466A3 US 0033161 W US0033161 W US 0033161W WO 0142466 A3 WO0142466 A3 WO 0142466A3
Authority
WO
WIPO (PCT)
Prior art keywords
zvwf1
von willebrand
willebrand factor
factor type
domain superfamily
Prior art date
Application number
PCT/US2000/033161
Other languages
French (fr)
Other versions
WO2001042466A2 (en
Inventor
James L Holloway
Original Assignee
Zymogenetics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Zymogenetics Inc filed Critical Zymogenetics Inc
Priority to AU20676/01A priority Critical patent/AU2067601A/en
Publication of WO2001042466A2 publication Critical patent/WO2001042466A2/en
Publication of WO2001042466A3 publication Critical patent/WO2001042466A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/745—Blood coagulation or fibrinolysis factors
    • C07K14/755—Factors VIII, e.g. factor VIII C (AHF), factor VIII Ag (VWF)
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hematology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

Proteins comprising one or more copies of von Willebrand factor type A domain play important roles in host defense mechanisms, such as immune response, inflammation, and hemostasis. Zvwf1 is a new member of this superfamily.
PCT/US2000/033161 1999-12-09 2000-12-07 Zvwf1: a member of the von willebrand factor type a domain superfamily WO2001042466A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU20676/01A AU2067601A (en) 1999-12-09 2000-12-07 Zvwf1: a member of the von willebrand factor type a domain superfamily

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45764599A 1999-12-09 1999-12-09
US09/457,645 1999-12-09

Publications (2)

Publication Number Publication Date
WO2001042466A2 WO2001042466A2 (en) 2001-06-14
WO2001042466A3 true WO2001042466A3 (en) 2002-01-10

Family

ID=23817578

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/033161 WO2001042466A2 (en) 1999-12-09 2000-12-07 Zvwf1: a member of the von willebrand factor type a domain superfamily

Country Status (2)

Country Link
AU (1) AU2067601A (en)
WO (1) WO2001042466A2 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same
CA2255477A1 (en) * 1998-12-11 2000-06-11 Uab Research Foundation Human vitreous and pharmaceutical compositions

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999063088A2 (en) * 1998-06-02 1999-12-09 Genentech, Inc. Membrane-bound proteins and nucleic acids encoding the same
CA2255477A1 (en) * 1998-12-11 2000-06-11 Uab Research Foundation Human vitreous and pharmaceutical compositions

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
DATABASE EMHUM1 EMBL; 23 January 1998 (1998-01-23), ROBERTSON N G ET AL., XP002170696 *
DATABASE EMHUM1 EMBL; 26 April 1999 (1999-04-26), CORDES M ET AL.: "The sequence of Homo sapiens BAC clone RP11-294L11", XP002170695 *
ROBERTSON NAHID G ET AL: "Mapping and characterization of a novel cochlear gene in human and in mouse: A positional candidate gene for a deafness disorder, DFNA9.", GENOMICS, vol. 46, no. 3, 15 December 1997 (1997-12-15), pages 345 - 354, XP002170694, ISSN: 0888-7543 *

Also Published As

Publication number Publication date
AU2067601A (en) 2001-06-18
WO2001042466A2 (en) 2001-06-14

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