WO2001040764A3 - Apparatus for the detection of particles - Google Patents

Apparatus for the detection of particles Download PDF

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Publication number
WO2001040764A3
WO2001040764A3 PCT/NL2000/000883 NL0000883W WO0140764A3 WO 2001040764 A3 WO2001040764 A3 WO 2001040764A3 NL 0000883 W NL0000883 W NL 0000883W WO 0140764 A3 WO0140764 A3 WO 0140764A3
Authority
WO
WIPO (PCT)
Prior art keywords
detection
particles
flow cell
provides
suspension
Prior art date
Application number
PCT/NL2000/000883
Other languages
French (fr)
Other versions
WO2001040764A2 (en
Inventor
George Bavo Joseph Dubelaar
Original Assignee
Dubelaar Res Instr Engineering
George Bavo Joseph Dubelaar
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dubelaar Res Instr Engineering, George Bavo Joseph Dubelaar filed Critical Dubelaar Res Instr Engineering
Priority to AU28916/01A priority Critical patent/AU2891601A/en
Publication of WO2001040764A2 publication Critical patent/WO2001040764A2/en
Publication of WO2001040764A3 publication Critical patent/WO2001040764A3/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N15/00—Investigating characteristics of particles; Investigating permeability, pore-volume or surface-area of porous materials
    • G01N15/10—Investigating individual particles
    • G01N15/14—Optical investigation techniques, e.g. flow cytometry
    • G01N15/1434—Optical arrangements
    • G01N2015/1438—Using two lasers in succession

Landscapes

  • Chemical & Material Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Materials By Optical Means (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)

Abstract

This invention provides an apparatus for the detection of individual particles in a suspension flowing through a transparent flow cell, further comprising of means to irradiate the suspension in this flow cell and means to detect the light emitted by the suspended particles. The irradiation means provides two identical coparallel and overlapping laser beams, with a lateral, relative displacement more or less equal to the beam radius, and polarized in relative orthogonal directions. This apparatus is also suited for the detection of larger particles.
PCT/NL2000/000883 1999-12-01 2000-12-01 Apparatus for the detection of particles WO2001040764A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU28916/01A AU2891601A (en) 1999-12-01 2000-12-01 Apparatus for the detection of particles

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
NL1013717 1999-12-01
NL1013717 1999-12-01

Publications (2)

Publication Number Publication Date
WO2001040764A2 WO2001040764A2 (en) 2001-06-07
WO2001040764A3 true WO2001040764A3 (en) 2001-12-06

Family

ID=19770348

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/NL2000/000883 WO2001040764A2 (en) 1999-12-01 2000-12-01 Apparatus for the detection of particles

Country Status (2)

Country Link
AU (1) AU2891601A (en)
WO (1) WO2001040764A2 (en)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7250098B2 (en) 2001-09-28 2007-07-31 Applera Corporation Multi-capillary array electrophoresis device
EP2426489B1 (en) * 2001-09-28 2019-02-20 Life Technologies Corporation Multi-capillary array electrophoresis device
DE102005028893B4 (en) * 2005-06-19 2007-12-06 Stiftung Alfred-Wegener-Institut für Polar- und Meeresforschung Stiftung des öffentlichen Rechts Device for particle detection in a depth-limited lens
DE102009020778B4 (en) 2008-05-08 2019-03-28 Jenoptik Optical Systems Gmbh Method for shaping material for measuring and / or metering devices
TW201405116A (en) * 2012-05-30 2014-02-01 Cytojene Corp Flow cytometer
US9746412B2 (en) 2012-05-30 2017-08-29 Iris International, Inc. Flow cytometer
CN116560096A (en) * 2022-01-30 2023-08-08 贝克曼库尔特生物科技（苏州）有限公司 Optical system for a sample processor and sample processor
CN114674760B (en) * 2022-05-30 2022-09-06 中国科学院海洋研究所 Symmetric marine planktonic algae polarization scattering multi-angle measuring instrument and measuring method thereof

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636075A (en) * 1984-08-22 1987-01-13 Particle Measuring Systems, Inc. Particle measurement utilizing orthogonally polarized components of a laser beam
JPH0235335A (en) * 1987-04-23 1990-02-05 Sumitomo Chem Co Ltd Method and apparatus for measuring fine grain
US4989977A (en) * 1985-07-29 1991-02-05 Becton, Dickinson And Company Flow cytometry apparatus with improved light beam adjustment
EP0424934A2 (en) * 1989-10-26 1991-05-02 Hitachi, Ltd. Apparatus for counting particles suspended in a fluid
JPH04184241A (en) * 1990-11-20 1992-07-01 Hitachi Ltd Particle analyser
US5133602A (en) * 1991-04-08 1992-07-28 International Business Machines Corporation Particle path determination system
US5134426A (en) * 1989-03-31 1992-07-28 Hitachi, Ltd. Optical device for generating pattern having uniform light intensity distribution
US5561515A (en) * 1994-10-07 1996-10-01 Tsi Incorporated Apparatus for measuring particle sizes and velocities

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4636075A (en) * 1984-08-22 1987-01-13 Particle Measuring Systems, Inc. Particle measurement utilizing orthogonally polarized components of a laser beam
US4989977A (en) * 1985-07-29 1991-02-05 Becton, Dickinson And Company Flow cytometry apparatus with improved light beam adjustment
JPH0235335A (en) * 1987-04-23 1990-02-05 Sumitomo Chem Co Ltd Method and apparatus for measuring fine grain
US5134426A (en) * 1989-03-31 1992-07-28 Hitachi, Ltd. Optical device for generating pattern having uniform light intensity distribution
EP0424934A2 (en) * 1989-10-26 1991-05-02 Hitachi, Ltd. Apparatus for counting particles suspended in a fluid
JPH04184241A (en) * 1990-11-20 1992-07-01 Hitachi Ltd Particle analyser
US5133602A (en) * 1991-04-08 1992-07-28 International Business Machines Corporation Particle path determination system
US5561515A (en) * 1994-10-07 1996-10-01 Tsi Incorporated Apparatus for measuring particle sizes and velocities

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 014, no. 189 (P - 1037) 17 April 1990 (1990-04-17) *
PATENT ABSTRACTS OF JAPAN vol. 016, no. 504 (P - 1439) 19 October 1992 (1992-10-19) *

Also Published As

Publication number Publication date
AU2891601A (en) 2001-06-12
WO2001040764A2 (en) 2001-06-07

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