WO2001036627A3 - Pharmaceutical compositions comprising acetylcholinesterase antisense deoxynucleotides for the treatment of muscular and neuromuscular disorders - Google Patents
Pharmaceutical compositions comprising acetylcholinesterase antisense deoxynucleotides for the treatment of muscular and neuromuscular disorders Download PDFInfo
- Publication number
- WO2001036627A3 WO2001036627A3 PCT/IL2000/000763 IL0000763W WO0136627A3 WO 2001036627 A3 WO2001036627 A3 WO 2001036627A3 IL 0000763 W IL0000763 W IL 0000763W WO 0136627 A3 WO0136627 A3 WO 0136627A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- treatment
- acetylcholinesterase
- muscular
- pharmaceutical compositions
- neuromuscular disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU15461/01A AU1546101A (en) | 1999-11-16 | 2000-11-16 | Pharmaceutical compositions comprising acetylcholinesterase antisense deoxynucleotides for the treatment of muscular and neuromuscular disorders |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IL132972 | 1999-11-16 | ||
IL13297299A IL132972A0 (en) | 1999-11-16 | 1999-11-16 | Pharmaceutical compositions comprising acetylcholinesterase antisense deoxynucleotides for the treatment of muscular and neuromuscular disorders |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001036627A2 WO2001036627A2 (en) | 2001-05-25 |
WO2001036627A3 true WO2001036627A3 (en) | 2001-10-04 |
Family
ID=11073493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IL2000/000763 WO2001036627A2 (en) | 1999-11-16 | 2000-11-16 | Pharmaceutical compositions comprising acetylcholinesterase antisense deoxynucleotides for the treatment of muscular and neuromuscular disorders |
Country Status (3)
Country | Link |
---|---|
AU (1) | AU1546101A (en) |
IL (1) | IL132972A0 (en) |
WO (1) | WO2001036627A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9328346B2 (en) | 2010-11-12 | 2016-05-03 | The General Hospital Corporation | Polycomb-associated non-coding RNAs |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL143379A (en) | 2001-05-24 | 2013-11-28 | Yissum Res Dev Co | Antisense oligonucleotide against the r isophorm of human ache and uses thereof |
US9920317B2 (en) | 2010-11-12 | 2018-03-20 | The General Hospital Corporation | Polycomb-associated non-coding RNAs |
JP2015523854A (en) | 2012-05-16 | 2015-08-20 | ラナ セラピューティクス インコーポレイテッド | Compositions and methods for modulating SMN gene family expression |
AP2014008100A0 (en) | 2012-05-16 | 2014-12-31 | Gen Hospital Corp | Compositions and methods for modulating hemoglobingene family expression |
US10837014B2 (en) | 2012-05-16 | 2020-11-17 | Translate Bio Ma, Inc. | Compositions and methods for modulating SMN gene family expression |
WO2013173608A1 (en) | 2012-05-16 | 2013-11-21 | Rana Therapeutics, Inc. | Compositions and methods for modulating mecp2 expression |
US10174323B2 (en) | 2012-05-16 | 2019-01-08 | The General Hospital Corporation | Compositions and methods for modulating ATP2A2 expression |
AU2013262656A1 (en) | 2012-05-16 | 2015-01-22 | Rana Therapeutics, Inc. | Compositions and methods for modulating UTRN expression |
CA2966044A1 (en) | 2014-10-30 | 2016-05-06 | The General Hospital Corporation | Methods for modulating atrx-dependent gene repression |
WO2016149455A2 (en) | 2015-03-17 | 2016-09-22 | The General Hospital Corporation | The rna interactome of polycomb repressive complex 1 (prc1) |
EP3969587A4 (en) * | 2019-05-13 | 2023-02-15 | The Trustees of The University of Pennsylvania | Compositions and methods of acetylcholine receptor chimeric autoantibody receptor cells |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993021202A1 (en) * | 1992-04-15 | 1993-10-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Synthetic antisense oligodeoxynucleotides and pharmaceutical compositions containing them |
WO1998026062A2 (en) * | 1996-12-12 | 1998-06-18 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Synthetic antisense oligodeoxynucleotides and pharmaceutical compositions containing them |
US5932780A (en) * | 1994-02-28 | 1999-08-03 | Yissum Research Development Company Of Hebrew University Of Jerusalem | Transgenic non-human animal assay system for anti-cholinesterase substances |
-
1999
- 1999-11-16 IL IL13297299A patent/IL132972A0/en unknown
-
2000
- 2000-11-16 AU AU15461/01A patent/AU1546101A/en not_active Abandoned
- 2000-11-16 WO PCT/IL2000/000763 patent/WO2001036627A2/en active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1993021202A1 (en) * | 1992-04-15 | 1993-10-28 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Synthetic antisense oligodeoxynucleotides and pharmaceutical compositions containing them |
US5932780A (en) * | 1994-02-28 | 1999-08-03 | Yissum Research Development Company Of Hebrew University Of Jerusalem | Transgenic non-human animal assay system for anti-cholinesterase substances |
WO1998026062A2 (en) * | 1996-12-12 | 1998-06-18 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Synthetic antisense oligodeoxynucleotides and pharmaceutical compositions containing them |
Non-Patent Citations (2)
Title |
---|
SEIDMAN S. ET AL.: "Antisense technologies have a future fighting neurodegenerative diseases", ANTISENSE & NUCLEIC ACID DRUG DEVELOPMENT, vol. 9, August 1999 (1999-08-01), pages 333 - 340, XP000984531 * |
TALMA BRENNER ET AL: "Antisense approach to the anticholinesterase management of myasthenia gravis.", JOURNAL OF AUTOIMMUNITY, no. SUPPL., 1999, 2nd International Congress on Autoimmunity;Tel Aviv, Israel; March 7-11, 1999, pages 22, XP000986370, ISSN: 0896-8411 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9328346B2 (en) | 2010-11-12 | 2016-05-03 | The General Hospital Corporation | Polycomb-associated non-coding RNAs |
Also Published As
Publication number | Publication date |
---|---|
WO2001036627A2 (en) | 2001-05-25 |
AU1546101A (en) | 2001-05-30 |
IL132972A0 (en) | 2001-03-19 |
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