WO2001036003A8 - Selective cellular targeting: multifunctional delivery vehicles - Google Patents

Selective cellular targeting: multifunctional delivery vehicles

Info

Publication number
WO2001036003A8
WO2001036003A8 PCT/US2000/031262 US0031262W WO0136003A8 WO 2001036003 A8 WO2001036003 A8 WO 2001036003A8 US 0031262 W US0031262 W US 0031262W WO 0136003 A8 WO0136003 A8 WO 0136003A8
Authority
WO
WIPO (PCT)
Prior art keywords
delivery vehicles
cellular targeting
selective cellular
multifunctional delivery
multifunctional
Prior art date
Application number
PCT/US2000/031262
Other languages
French (fr)
Other versions
WO2001036003A2 (en
Inventor
Arnold Glazier
Original Assignee
Drug Innovation & Design Inc
Arnold Glazier
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drug Innovation & Design Inc, Arnold Glazier filed Critical Drug Innovation & Design Inc
Priority to CA002391534A priority Critical patent/CA2391534A1/en
Priority to AU16075/01A priority patent/AU1607501A/en
Priority to EP00978631A priority patent/EP1255567A1/en
Publication of WO2001036003A2 publication Critical patent/WO2001036003A2/en
Publication of WO2001036003A8 publication Critical patent/WO2001036003A8/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B82—NANOTECHNOLOGY
    • B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
PCT/US2000/031262 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles WO2001036003A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
CA002391534A CA2391534A1 (en) 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles
AU16075/01A AU1607501A (en) 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles
EP00978631A EP1255567A1 (en) 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US16548599P 1999-11-15 1999-11-15
US60/165,485 1999-11-15
US23947800P 2000-10-11 2000-10-11
US60/239,478 2000-10-11
US24193700P 2000-10-20 2000-10-20
US60/241,939 2000-10-20

Publications (2)

Publication Number Publication Date
WO2001036003A2 WO2001036003A2 (en) 2001-05-25
WO2001036003A8 true WO2001036003A8 (en) 2002-06-06

Family

ID=27389154

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/031262 WO2001036003A2 (en) 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles

Country Status (2)

Country Link
AU (1) AU1607501A (en)
WO (1) WO2001036003A2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002042259A2 (en) 2000-11-27 2002-05-30 University Of Maryland, Baltimore Methods of synthesizing and using derivatives of [2-(2-aminoethoxy)ethoxy] acetic acid
CA2451188A1 (en) * 2001-06-25 2003-01-03 Drug Innovation & Design, Incorporated Exponential pattern recognition based cellular targeting, compositions, methods and anticancer applications
EP2075256A2 (en) 2002-01-14 2009-07-01 William Herman Multispecific binding molecules
WO2003074551A2 (en) 2002-03-01 2003-09-12 The Administrators Of The Tulane Educational Fund Conjugates of therapeutic or cytotoxic agents and biologically active peptides
US7915306B2 (en) 2002-03-08 2011-03-29 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
EP2308861B1 (en) 2002-03-08 2017-03-01 Eisai R&D Management Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
DE10300098A1 (en) * 2003-01-07 2004-07-15 Bayer Ag Copper-carbene complexes and their use
US6987270B2 (en) 2003-05-07 2006-01-17 General Electric Company Method to account for event losses due to positron range in positron emission tomography and assay of positron-emitting isotopes
TWI385169B (en) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd Heterocyclic substituted pyridine derivatives and antifungal agent containing same
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
CN105748465A (en) 2007-07-25 2016-07-13 卫材R&D管理株式会社 Multikinase Inhibitors For Use In The Treatment Of Cancer
US8513287B2 (en) 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US8188119B2 (en) 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
GB0914883D0 (en) 2009-08-26 2009-09-30 Univ Belfast Compound
US20140140959A1 (en) 2012-10-05 2014-05-22 Aladar A. Szalay Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes
RU2737434C2 (en) 2013-03-13 2020-11-30 Форма Терапьютикс, Инк. Novel compounds and fasn inhibition compositions
US20140271465A1 (en) * 2013-03-15 2014-09-18 Mallinckrodt Llc Matrix metalloprotease (mmp) targeted agents for imaging and therapy
GB201315335D0 (en) * 2013-08-29 2013-10-09 Of Singapore Amino diacids containing peptide modifiers
AU2014369019B2 (en) 2013-12-19 2020-09-17 Seagen Inc. Methylene carbamate linkers for use with targeted-drug conjugates
US10464955B2 (en) 2014-02-28 2019-11-05 Hangzhou Dac Biotech Co., Ltd. Charged linkers and their uses for conjugation
WO2015179823A2 (en) * 2014-05-23 2015-11-26 The California Institute For Biomedical Research Lung localized inhibitors of alpha(v)beta 6
WO2015200349A2 (en) * 2014-06-24 2015-12-30 The California Institute For Biomedical Research Elastase inhibitors
TWI767148B (en) 2018-10-10 2022-06-11 美商弗瑪治療公司 Inhibiting fatty acid synthase (fasn)
GB201816825D0 (en) * 2018-10-16 2018-11-28 Phoremost Ltd Target for anti-cancer therapy
US10793554B2 (en) 2018-10-29 2020-10-06 Forma Therapeutics, Inc. Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone
WO2020096775A1 (en) * 2018-11-09 2020-05-14 R.P. Scherer Technologies, Llc Sulfatase-cleavable linkers for antibody-drug conjugates

Also Published As

Publication number Publication date
WO2001036003A2 (en) 2001-05-25
AU1607501A (en) 2001-05-30

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