WO2001036003A8 - Selective cellular targeting: multifunctional delivery vehicles - Google Patents
Selective cellular targeting: multifunctional delivery vehiclesInfo
- Publication number
- WO2001036003A8 WO2001036003A8 PCT/US2000/031262 US0031262W WO0136003A8 WO 2001036003 A8 WO2001036003 A8 WO 2001036003A8 US 0031262 W US0031262 W US 0031262W WO 0136003 A8 WO0136003 A8 WO 0136003A8
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- delivery vehicles
- cellular targeting
- selective cellular
- multifunctional delivery
- multifunctional
- Prior art date
Links
- 230000001413 cellular effect Effects 0.000 title 1
- 230000008685 targeting Effects 0.000 title 1
Classifications
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y5/00—Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/54—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
- A61K47/55—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/69—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
- A61K47/6949—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Nanotechnology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biotechnology (AREA)
- Crystallography & Structural Chemistry (AREA)
- Biophysics (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- General Engineering & Computer Science (AREA)
- Prostheses (AREA)
- Detergent Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP00978631A EP1255567A1 (en) | 1999-11-15 | 2000-11-14 | Selective cellular targeting: multifunctional delivery vehicles |
| CA002391534A CA2391534A1 (en) | 1999-11-15 | 2000-11-14 | Selective cellular targeting: multifunctional delivery vehicles |
| AU16075/01A AU1607501A (en) | 1999-11-15 | 2000-11-14 | Selective cellular targeting: multifunctional delivery vehicles |
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16548599P | 1999-11-15 | 1999-11-15 | |
| US60/165,485 | 1999-11-15 | ||
| US23947800P | 2000-10-11 | 2000-10-11 | |
| US60/239,478 | 2000-10-11 | ||
| US24193700P | 2000-10-20 | 2000-10-20 | |
| US60/241,939 | 2000-10-20 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| WO2001036003A2 WO2001036003A2 (en) | 2001-05-25 |
| WO2001036003A8 true WO2001036003A8 (en) | 2002-06-06 |
Family
ID=27389154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| PCT/US2000/031262 WO2001036003A2 (en) | 1999-11-15 | 2000-11-14 | Selective cellular targeting: multifunctional delivery vehicles |
Country Status (2)
| Country | Link |
|---|---|
| AU (1) | AU1607501A (en) |
| WO (1) | WO2001036003A2 (en) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2002042259A2 (en) * | 2000-11-27 | 2002-05-30 | University Of Maryland, Baltimore | Methods of synthesizing and using derivatives of [2-(2-aminoethoxy)ethoxy] acetic acid |
| US20030031677A1 (en) * | 2001-06-25 | 2003-02-13 | Drug Innovation & Design, Incorporated | Exponential pattern recognition based cellular targeting, compositions, methods and anticancer applications |
| US20050069549A1 (en) | 2002-01-14 | 2005-03-31 | William Herman | Targeted ligands |
| AU2003220011B2 (en) | 2002-03-01 | 2008-05-29 | The Administrators Of The Tulane Educational Fund | Conjugates of therapeutic or cytotoxic agents and biologically active peptides |
| US7915306B2 (en) | 2002-03-08 | 2011-03-29 | Eisai Co., Ltd. | Macrocyclic compounds useful as pharmaceuticals |
| CA2478065C (en) | 2002-03-08 | 2013-01-08 | Eisai Co. Ltd. | Macrocyclic compounds useful as pharmaceuticals |
| DE10300098A1 (en) * | 2003-01-07 | 2004-07-15 | Bayer Ag | Copper-carbene complexes and their use |
| US6987270B2 (en) | 2003-05-07 | 2006-01-17 | General Electric Company | Method to account for event losses due to positron range in positron emission tomography and assay of positron-emitting isotopes |
| TWI385169B (en) | 2005-10-31 | 2013-02-11 | Eisai R&D Man Co Ltd | Heterocyclic substituted pyridine derivatives and antifungal agent containing same |
| TW200841879A (en) | 2007-04-27 | 2008-11-01 | Eisai R&D Man Co Ltd | Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same |
| CN105748465A (en) | 2007-07-25 | 2016-07-13 | 卫材R&D管理株式会社 | Multikinase Inhibitors For Use In The Treatment Of Cancer |
| US8513287B2 (en) | 2007-12-27 | 2013-08-20 | Eisai R&D Management Co., Ltd. | Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same |
| US8188119B2 (en) | 2008-10-24 | 2012-05-29 | Eisai R&D Management Co., Ltd | Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same |
| GB0914883D0 (en) | 2009-08-26 | 2009-09-30 | Univ Belfast | Compound |
| WO2014055960A1 (en) | 2012-10-05 | 2014-04-10 | Genelux Corporation | Energy absorbing-based diagnostic and therapeutic methods employing nucleic acid molecules encoding chromophore-producing enzymes |
| EP2968316B1 (en) | 2013-03-13 | 2019-08-07 | Forma Therapeutics, Inc. | 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (fasn) inhibitors for the treatment of cancer |
| WO2014151988A1 (en) * | 2013-03-15 | 2014-09-25 | Mallinckrodt Llc | Matrix metalloprotease (mmp) targeted agents for imaging and therapy |
| GB201315335D0 (en) | 2013-08-29 | 2013-10-09 | Of Singapore | Amino diacids containing peptide modifiers |
| IL290330B2 (en) | 2013-12-19 | 2023-09-01 | Seagen Inc | Methylene carbamate linkers for use with targeted-drug conjugates |
| CA2938919C (en) | 2014-02-28 | 2020-12-29 | Hangzhou Dac Biotech Co., Ltd | Charged linkers and their uses for conjugation |
| WO2015179823A2 (en) * | 2014-05-23 | 2015-11-26 | The California Institute For Biomedical Research | Lung localized inhibitors of alpha(v)beta 6 |
| WO2015200349A2 (en) * | 2014-06-24 | 2015-12-30 | The California Institute For Biomedical Research | Elastase inhibitors |
| TWI767148B (en) | 2018-10-10 | 2022-06-11 | 美商弗瑪治療公司 | Inhibiting fatty acid synthase (fasn) |
| GB201816825D0 (en) * | 2018-10-16 | 2018-11-28 | Phoremost Ltd | Target for anti-cancer therapy |
| CN113382633A (en) | 2018-10-29 | 2021-09-10 | 福马治疗股份有限公司 | Solid forms of (4- (2-fluoro-4- (1-methyl-1H-benzo [ d ] imidazol-5-yl) benzoyl) piperazin-1-yl) (1-hydroxycyclopropyl) methanone |
| US11980668B2 (en) | 2018-11-09 | 2024-05-14 | R.P. Scherer Technologies, Llc | Sulfatase-cleavable linkers for antibody-drug conjugates |
-
2000
- 2000-11-14 WO PCT/US2000/031262 patent/WO2001036003A2/en active Search and Examination
- 2000-11-14 AU AU16075/01A patent/AU1607501A/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| AU1607501A (en) | 2001-05-30 |
| WO2001036003A2 (en) | 2001-05-25 |
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