WO2001036003A8 - Selective cellular targeting: multifunctional delivery vehicles - Google Patents

Selective cellular targeting: multifunctional delivery vehicles

Info

Publication number
WO2001036003A8
WO2001036003A8 PCT/US2000/031262 US0031262W WO0136003A8 WO 2001036003 A8 WO2001036003 A8 WO 2001036003A8 US 0031262 W US0031262 W US 0031262W WO 0136003 A8 WO0136003 A8 WO 0136003A8
Authority
WO
WIPO (PCT)
Prior art keywords
delivery vehicles
cellular targeting
selective cellular
multifunctional delivery
multifunctional
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
PCT/US2000/031262
Other languages
French (fr)
Other versions
WO2001036003A2 (en
Inventor
Arnold Glazier
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Drug Innovation and Design Inc
Original Assignee
Drug Innovation and Design Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Drug Innovation and Design Inc filed Critical Drug Innovation and Design Inc
Priority to AU16075/01A priority Critical patent/AU1607501A/en
Priority to EP00978631A priority patent/EP1255567A1/en
Priority to CA002391534A priority patent/CA2391534A1/en
Publication of WO2001036003A2 publication Critical patent/WO2001036003A2/en
Anticipated expiration legal-status Critical
Publication of WO2001036003A8 publication Critical patent/WO2001036003A8/en
Ceased legal-status Critical Current

Links

Classifications

    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y5/00Nanobiotechnology or nanomedicine, e.g. protein engineering or drug delivery
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/54Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound
    • A61K47/55Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic compound the modifying agent being also a pharmacologically or therapeutically active agent, i.e. the entire conjugate being a codrug, i.e. a dimer, oligomer or polymer of pharmacologically or therapeutically active compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/69Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit
    • A61K47/6949Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the conjugate being characterised by physical or galenical forms, e.g. emulsion, particle, inclusion complex, stent or kit inclusion complexes, e.g. clathrates, cavitates or fullerenes

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Nanotechnology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Prostheses (AREA)
  • Detergent Compositions (AREA)
PCT/US2000/031262 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles Ceased WO2001036003A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU16075/01A AU1607501A (en) 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles
EP00978631A EP1255567A1 (en) 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles
CA002391534A CA2391534A1 (en) 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US16548599P 1999-11-15 1999-11-15
US60/165,485 1999-11-15
US23947800P 2000-10-11 2000-10-11
US60/239,478 2000-10-11
US24193700P 2000-10-20 2000-10-20
US60/241,939 2000-10-20

Publications (2)

Publication Number Publication Date
WO2001036003A2 WO2001036003A2 (en) 2001-05-25
WO2001036003A8 true WO2001036003A8 (en) 2002-06-06

Family

ID=27389154

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/031262 Ceased WO2001036003A2 (en) 1999-11-15 2000-11-14 Selective cellular targeting: multifunctional delivery vehicles

Country Status (2)

Country Link
AU (1) AU1607501A (en)
WO (1) WO2001036003A2 (en)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002042259A2 (en) * 2000-11-27 2002-05-30 University Of Maryland, Baltimore Methods of synthesizing and using derivatives of [2-(2-aminoethoxy)ethoxy] acetic acid
US20030031677A1 (en) * 2001-06-25 2003-02-13 Drug Innovation & Design, Incorporated Exponential pattern recognition based cellular targeting, compositions, methods and anticancer applications
US20050069549A1 (en) 2002-01-14 2005-03-31 William Herman Targeted ligands
CN102133407A (en) 2002-03-01 2011-07-27 图兰恩教育基金管理人 Conjugates of therapeutic or cytotoxic agents and biologically active peptides
ES2555307T3 (en) 2002-03-08 2015-12-30 Eisai R&D Management Co., Ltd. Macrocyclic compounds useful as pharmaceutical agents
US7915306B2 (en) 2002-03-08 2011-03-29 Eisai Co., Ltd. Macrocyclic compounds useful as pharmaceuticals
DE10300098A1 (en) * 2003-01-07 2004-07-15 Bayer Ag Copper-carbene complexes and their use
US6987270B2 (en) 2003-05-07 2006-01-17 General Electric Company Method to account for event losses due to positron range in positron emission tomography and assay of positron-emitting isotopes
TWI385169B (en) 2005-10-31 2013-02-11 Eisai R&D Man Co Ltd Heterocyclic substituted pyridine derivatives and antifungal agent containing same
TW200841879A (en) 2007-04-27 2008-11-01 Eisai R&D Man Co Ltd Pyridine derivatives substituted by heterocyclic ring and phosphonoamino group, and anti-fungal agent containing same
AU2008279027B8 (en) 2007-07-25 2014-03-06 Eisai R & D Management Co., Ltd. Multikinase inhibitors for use in the treatment of cancer
US8513287B2 (en) 2007-12-27 2013-08-20 Eisai R&D Management Co., Ltd. Heterocyclic ring and phosphonoxymethyl group substituted pyridine derivatives and antifungal agent containing same
US8188119B2 (en) 2008-10-24 2012-05-29 Eisai R&D Management Co., Ltd Pyridine derivatives substituted with heterocyclic ring and γ-glutamylamino group, and antifungal agents containing same
GB0914883D0 (en) 2009-08-26 2009-09-30 Univ Belfast Compound
US20140140959A1 (en) 2012-10-05 2014-05-22 Aladar A. Szalay Energy Absorbing-Based Diagnostic and Therapeutic Methods Employing Nucleic Acid Molecules Encoding Chromophore-Producing Enzymes
LT2968316T (en) 2013-03-13 2019-10-25 Forma Therapeutics Inc 2-hydroxy-1-{4-[(4-phenylphenyl)carbonyl]piperazin-1-yl}ethan-1-one derivatives and related compounds as fatty acid synthase (fasn) inhibitors for the treatment of cancer
WO2014151988A1 (en) * 2013-03-15 2014-09-25 Mallinckrodt Llc Matrix metalloprotease (mmp) targeted agents for imaging and therapy
GB201315335D0 (en) 2013-08-29 2013-10-09 Of Singapore Amino diacids containing peptide modifiers
CA2932647C (en) 2013-12-19 2022-06-14 Seattle Genetics, Inc. Methylene carbamate linkers for use with targeted-drug conjugates
PT3122757T (en) 2014-02-28 2023-11-03 Hangzhou Dac Biotech Co Ltd Charged linkers and their uses for conjugation
WO2015179823A2 (en) * 2014-05-23 2015-11-26 The California Institute For Biomedical Research Lung localized inhibitors of alpha(v)beta 6
WO2015200349A2 (en) * 2014-06-24 2015-12-30 The California Institute For Biomedical Research Elastase inhibitors
TWI767148B (en) 2018-10-10 2022-06-11 美商弗瑪治療公司 Inhibiting fatty acid synthase (fasn)
GB201816825D0 (en) * 2018-10-16 2018-11-28 Phoremost Ltd Target for anti-cancer therapy
US10793554B2 (en) 2018-10-29 2020-10-06 Forma Therapeutics, Inc. Solid forms of 4-(2-fluoro-4-(1-methyl-1H-benzo[d]imidazol-5-yl)benzoyl)piperazin-1-yl)(1-hydroxycyclopropyl)methanone
WO2020096775A1 (en) * 2018-11-09 2020-05-14 R.P. Scherer Technologies, Llc Sulfatase-cleavable linkers for antibody-drug conjugates

Also Published As

Publication number Publication date
WO2001036003A2 (en) 2001-05-25
AU1607501A (en) 2001-05-30

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