WO2001024641A1 - Method of increasing feed intake - Google Patents

Method of increasing feed intake Download PDF

Info

Publication number
WO2001024641A1
WO2001024641A1 PCT/JP2000/006912 JP0006912W WO0124641A1 WO 2001024641 A1 WO2001024641 A1 WO 2001024641A1 JP 0006912 W JP0006912 W JP 0006912W WO 0124641 A1 WO0124641 A1 WO 0124641A1
Authority
WO
WIPO (PCT)
Prior art keywords
feed
glutamine
livestock
feed intake
monogastric
Prior art date
Application number
PCT/JP2000/006912
Other languages
French (fr)
Japanese (ja)
Inventor
Izuru Shinzato
Hiroyuki Sato
Yoshihiro Takuma
Tamotsu Suzuki
Original Assignee
Ajinomoto Co., Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ajinomoto Co., Inc. filed Critical Ajinomoto Co., Inc.
Publication of WO2001024641A1 publication Critical patent/WO2001024641A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K50/00—Feeding-stuffs specially adapted for particular animals
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23K—FODDER
    • A23K20/00—Accessory food factors for animal feeding-stuffs
    • A23K20/10—Organic substances
    • A23K20/142—Amino acids; Derivatives thereof

Definitions

  • the present invention relates to a method for improving feed intake of monogastric livestock.
  • breast milk contains several factors that help develop and maintain small intestinal function in children. Among them, glutamine is a major free amino acid in breast milk, and it has been suggested that this amino acid is essential for the development and maintenance of small intestinal function in animals [Nutrition Review, 48.297 (1990)]. It is also known that the concentration of free glutamine in pig breast milk increases as lactation proceeds [J. Nutr. 124, 415-424 (1994)].
  • An object of the present invention is to provide a method for improving feed intake of monogastric livestock.
  • the present inventors have found that administration of a feed supplemented with glutamine improves feed intake of monogastric livestock and promotes growth, thereby completing the present invention. Reached. That is, the present invention relates to a method for increasing feed intake of monogastric livestock by adding glutamine to the monogastric livestock feed and administering the glutamine to the monogastric livestock.
  • a single stomach livestock is a livestock having a single stomach-structured stomach, such as pigs and chickens.
  • Glutamine used in the present invention is glutamine which exists as an amino acid alone, unlike glutamine which is a protein contained in feed. This glutamine can be used in both the L-form and the D-form, but the L-form is preferred from the viewpoint of utilization efficiency.
  • Glutamine includes synthetic methods or fermentation Glutamine produced by the method can be used, but its origin is not particularly limited.
  • Glutamine-added monogastric livestock feeds usually include corn, barley, wheat, rye, sorghum, soybeans, yellow flour, and other cereals, soybean oil cake, soybean protein, oil and fat, skim milk, fish meal, meat-and-bone meal, blood meal, plasma Protein, whey, rice bran, bran, sugar, glucose, minerals, vitamins, salt, etc. may be used alone or in combination.
  • Glutamine is administered at a dose of 0.1 to 5.0%, preferably 0.5 to 2.0%, to a commonly used feed, and the glutamine-containing feed is fed to a single stomach livestock, whereby the glutamine is fed to a domestic animal at a weight of 1 kg. It is preferable to administer 0.05 to 5.0 g per dose, preferably 0.1 to 2.0 g.
  • Glutamine can be added to feed and mixed to feed livestock.
  • pre-starter feed pre-initial feed
  • Glutamine can increase feed intake when added to any of these feeds, but is particularly effective when added to prestarter and starter feeds.
  • Glutamine can also be given separately from the diet, in combination with glutamine alone or in combination with sugars that livestock prefers.
  • the method for improving feed intake by glutamine according to the present invention is useful for application to monogastric livestock from the time immediately after birth to immediately before the feed is switched to the fattening period after weaning, especially for pigs. It is.
  • Example 1 Improvement of feed intake of piglets

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Animal Husbandry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Fodder In General (AREA)
  • Feed For Specific Animals (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

A method of increasing the feed intake of monogastric livestock which is characterized by adding glutamine to feeds for monogastric livestock and feeding monogastric livestock with these feeds.

Description

明 細 書 飼料摂取量の増加方法 技術分野  Description How to increase feed intake Technical field
本発明は、 単胃家畜の飼料摂取量を向上させる方法に関する。  The present invention relates to a method for improving feed intake of monogastric livestock.
背景技術  Background art
出生直後から離乳期を経て飼料が肥育期用に切リ替わる直前までの家畜は、 母 乳から固形飼料に切り替わるストレスの影響で飼料摂取が低下し成長の遅延を引 き起こす。 この時期の飼料摂取量増進を目的として甘味料など嗜好性の高い原料 を添加した飼料の給与などが試みられているが、 明瞭な効果が認められないのが 現状である。  Livestock from the time immediately after birth through the weaning period to just before the feed is switched to the fattening period, the effect of the stress of switching from breast milk to solid feed decreases feed intake and delays growth. Attempts to increase feed intake during this period, such as feeding feeds with highly palatable ingredients such as sweeteners, have been attempted, but no clear effect has been observed at present.
母乳は子供の小腸機能発達と維持を図るため、 いくつかの因子を含むと推測さ れている。 その中でもグルタミンは母乳中の主要遊離ァミノ酸であることから、 このアミノ酸が動物の小腸機能発達とその維持に必須であるとする説もある [Nutrition Review, 48. 297 (1990)〕。また豚母乳中の遊離グルタミン濃度は泌乳が 進むにつれ増加してくることが知られている 〔J. Nutr. 124, 415-424 (1994)〕。  It is speculated that breast milk contains several factors that help develop and maintain small intestinal function in children. Among them, glutamine is a major free amino acid in breast milk, and it has been suggested that this amino acid is essential for the development and maintenance of small intestinal function in animals [Nutrition Review, 48.297 (1990)]. It is also known that the concentration of free glutamine in pig breast milk increases as lactation proceeds [J. Nutr. 124, 415-424 (1994)].
発明の開示  Disclosure of the invention
本発明の目的は、 単胃家畜の飼料摂取量を向上させるための方法を提供するこ とにある。  An object of the present invention is to provide a method for improving feed intake of monogastric livestock.
本発明者らは、 種々の検討を重ねた結果、 グルタミンを添加した飼料を投与す ることにより、 単胃家畜の飼料摂取量が向上し発育が促進されることを見出し、 本発明を完成するに至った。 すなわち本発明は、 単胃家畜用飼料にグルタミンを 添加し、 これを単胃家畜に投与することにより、 単胃家畜の飼料摂取量を増加す る方法に関する。  As a result of various studies, the present inventors have found that administration of a feed supplemented with glutamine improves feed intake of monogastric livestock and promotes growth, thereby completing the present invention. Reached. That is, the present invention relates to a method for increasing feed intake of monogastric livestock by adding glutamine to the monogastric livestock feed and administering the glutamine to the monogastric livestock.
以下、 本発明を詳細に説明する。 単胃家畜とは単一嚢構造の胃を有する家畜で あり、 例えば豚、 鶏などが挙げられる。 本発明で使用するグルタミンは、 飼料中 に含まれている蛋白質のグルタミンとは異なり、 アミノ酸単体として存在するグ ルタミンである。このグルタミンは L体および D体のいずれも使用可能であるが、 利用効率の点から L体の方が好ましし、。 グルタミンとしては、 合成法または発酵 法で製造されたグルタミンが使用可能であるが、 その由来は特に問わない。 Hereinafter, the present invention will be described in detail. A single stomach livestock is a livestock having a single stomach-structured stomach, such as pigs and chickens. Glutamine used in the present invention is glutamine which exists as an amino acid alone, unlike glutamine which is a protein contained in feed. This glutamine can be used in both the L-form and the D-form, but the L-form is preferred from the viewpoint of utilization efficiency. Glutamine includes synthetic methods or fermentation Glutamine produced by the method can be used, but its origin is not particularly limited.
グルタミンを添加する単胃家畜用飼料としては、 通常、 とうもろこし、 大麦、 小麦、ライ麦、 ソルガム、大豆、黄粉などの穀類、大豆油かす、大豆蛋白、油脂、 スキムミルク、魚粉、肉骨粉、血粉、血漿蛋白、ホエー、 米ぬか、ふすま、砂糖、 ブドウ糖、 ミネラル、 ビタミン、 食塩などを単独あるいは組み合わせたものを用 いればよい。 グルタミンの投与量としては、 通常用いられる飼料にグルタミンを 0.1〜5.0%の割合、 好ましくは 0.5~2.0%で添加し、 該グルタミン含有飼料を単胃 家畜に給餌して、 グルタミンを家畜体重 1 k gあたり 0.05〜5.0 g Z曰、 好ましく は 0.1〜 2.0 gノ曰投与するのが望ましい。  Glutamine-added monogastric livestock feeds usually include corn, barley, wheat, rye, sorghum, soybeans, yellow flour, and other cereals, soybean oil cake, soybean protein, oil and fat, skim milk, fish meal, meat-and-bone meal, blood meal, plasma Protein, whey, rice bran, bran, sugar, glucose, minerals, vitamins, salt, etc. may be used alone or in combination. Glutamine is administered at a dose of 0.1 to 5.0%, preferably 0.5 to 2.0%, to a commonly used feed, and the glutamine-containing feed is fed to a single stomach livestock, whereby the glutamine is fed to a domestic animal at a weight of 1 kg. It is preferable to administer 0.05 to 5.0 g per dose, preferably 0.1 to 2.0 g.
グルタミンは飼料に添加、 混合して家畜に給餌できる。 例えば養豚業において は、 出生直後は母乳のみであるが、 次第に母乳と前初期飼料 （プレスターター飼 料） が平行投与され、 離乳とともに初期飼料 (スターター飼料)に切り替えられ、 その後肥育期飼料を用いて肥育される。 グルタミンはこれらいずれの飼料に添加 しても飼料摂取量を増加させることができるが、 特にプレスターター飼料および スターター飼料に添加すると効果的である。 また、 グルタミンは食餌とは別にグ ルタミン単独あるいは家畜が好んで摂取する砂糖などと混合して与えることもで さる。  Glutamine can be added to feed and mixed to feed livestock. For example, in the pig farming industry, only breast milk is used immediately after birth, but gradually breast milk and pre-initial feed (pre-starter feed) are administered in parallel, switched to the initial feed (starter feed) with weaning, and then used in the fattening season. Be fattened. Glutamine can increase feed intake when added to any of these feeds, but is particularly effective when added to prestarter and starter feeds. Glutamine can also be given separately from the diet, in combination with glutamine alone or in combination with sugars that livestock prefers.
本発明のグルタミンによる飼料摂取量向上方法は、 産業上は出生直後から離乳 期を経て飼料が肥育期用に切り替わる直前までの単胃家畜への適用が有用であり、 特に豚への適用が有用である。  The method for improving feed intake by glutamine according to the present invention is useful for application to monogastric livestock from the time immediately after birth to immediately before the feed is switched to the fattening period after weaning, especially for pigs. It is.
発明を実施するための最良の形態  BEST MODE FOR CARRYING OUT THE INVENTION
以下、 実施例を挙げて本発明を具体的に説明する。  Hereinafter, the present invention will be described specifically with reference to examples.
実施例 1 ：子豚の飼料摂取量向上 Example 1: Improvement of feed intake of piglets
離乳子豚 ·去勢雄 10頭、 雌 10頭を用い、 対照区 10頭とグルタミン投与区 10 頭の 2群に分けた。出生後 15曰齢時点より母乳と平行してプレスタータ一飼料を 給与した子豚を 22曰齢時点で離乳させ、 離乳から 15日間、 対照区には表一 1に 示す組成の市販スターター飼料を、 ゲルタミン投与区には表一 1の市販スタータ 一飼料に L一グルタミンを 1.0%添加した試験飼料を給与した。離乳後 0、 5、 15 曰目に体重と残飼重量を測定し、 飼料摂取量と増体重量、 飼料効率を算出した。 結果を表一 2に示す。 表 1 スタータ一飼料の配合組成 Weaned piglets · Ten castrated males and ten females were used and divided into two groups: 10 control groups and 10 glutamine-administered groups. Piglets fed a prestarter feed in parallel with breast milk from the age of 15 after birth were weaned at the age of 22 and 15 days after weaning, and the control group received a commercial starter feed with the composition shown in Table 11 for weaning. The test feed in which 1.0% L-glutamine was added to one feed of the commercial starter shown in Table 1 was fed to the gertamine administration group. After weaning, the body weight and remaining weight were measured at 0, 5, and 15 and the feed intake, weight gain, and feed efficiency were calculated. The results are shown in Table 1-2. Table 1 Composition of starter feed
Figure imgf000004_0001
Figure imgf000004_0001
Figure imgf000004_0002
以上の結果から、 グルタミンを飼料に添加することにより離乳子豚の飼料摂取 量が向上し、 飼料効率の改善も見られ、 発育が促進した。 特に離乳後 5曰目以降 は、 対照区に比べ、 飼料摂取量が 41 % (0.265対 0.374gZday) 向上しており、 そ の結果、 増体重量で 84% (0.1 55 0.285kgZday)、 飼料効率で 31 % (0.58対 0.76) の改善効果が認められた。
Figure imgf000004_0002
From the above results, it was found that the addition of glutamine to feed increased the feed intake of weaned piglets, improved feed efficiency, and promoted growth. In particular, after the fifth weaning, feed intake increased by 41% (0.265 vs. 0.374gZday) compared to the control group, resulting in 84% (0.155 0.285kgZday) in weight gain and feed efficiency. The improvement effect of 31% (0.58 vs 0.76) was recognized.
産業上の利用可能性  Industrial applicability
本発明によし J、単胃家畜の飼料摂取量を増加することが可能になり、その結果、 発育促進、 体重増加、 飼料効率の改善等の効果を得ることができる。  ADVANTAGE OF THE INVENTION According to this invention, it becomes possible to increase the feed intake of a single stomach domestic animal, As a result, effects, such as growth promotion, weight gain, and improvement of feed efficiency, can be acquired.

Claims

請 求 の 範 囲 The scope of the claims
1 . 単胃家畜用飼料にグルタミンを添加し、 これを単胃家畜に投与すること を特徴とする単胃家畜の飼料摂取量を増加する方法。 1. A method for increasing feed intake of monogastric livestock, which comprises adding glutamine to monogastric livestock feed and administering it to monogastric livestock.
2. 単胃家畜用飼料がスタータ一飼料またはプレスタータ一飼料であること を特徴とする請求の範囲 1項に記載の方法。 2. The method according to claim 1, wherein the single stomach livestock feed is a starter feed or a prestarter feed.
3 . グルタミンの添加量が飼料あたリ 0. 1 ~ 5重量％であることを特徴と する請求の範囲 1項に記載の方法。 3. The method according to claim 1, wherein the amount of glutamine to be added is 0.1 to 5% by weight of the feed.
PCT/JP2000/006912 1999-10-06 2000-10-04 Method of increasing feed intake WO2001024641A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP28576699A JP2001103910A (en) 1999-10-06 1999-10-06 Method for increasing intake of feed
JP11/285766 1999-10-06

Publications (1)

Publication Number Publication Date
WO2001024641A1 true WO2001024641A1 (en) 2001-04-12

Family

ID=17695785

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP2000/006912 WO2001024641A1 (en) 1999-10-06 2000-10-04 Method of increasing feed intake

Country Status (2)

Country Link
JP (1) JP2001103910A (en)
WO (1) WO2001024641A1 (en)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06209719A (en) * 1993-01-13 1994-08-02 Kyowa Hakko Kogyo Co Ltd Feed
JPH06303918A (en) * 1993-04-23 1994-11-01 Smith Kline Biichiyamu Nippon Zenyaku Kk Feed additive composition for swine and poultry

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06209719A (en) * 1993-01-13 1994-08-02 Kyowa Hakko Kogyo Co Ltd Feed
JPH06303918A (en) * 1993-04-23 1994-11-01 Smith Kline Biichiyamu Nippon Zenyaku Kk Feed additive composition for swine and poultry

Also Published As

Publication number Publication date
JP2001103910A (en) 2001-04-17

Similar Documents

Publication Publication Date Title
CA2731281C (en) Additive for livestock feed and feed composition for livestock
Sarwar et al. Nutritional management for buffalo production
JPH06209719A (en) Feed
CN113453560A (en) Flavonoids and animal health and productivity
CN106376734A (en) Instant milk type piglet early stage mixed feed
KR20010074799A (en) Method for Increasing Milk Production in Lactating Dairy Cattle
US4534969A (en) Method for improving lactation in ruminant animals
KR101313142B1 (en) Pig feed, and method for feeding same
MXPA03009810A (en) Method of enhancing reproductive performance in sows.
KR102633086B1 (en) Feed additive for dairy cattle comprising N-acetyl-L-tryptophan as active ingredient
Mc Gilliard Modifying proteins for maximum utilization in the ruminant
EP2844078B1 (en) Method of feeding a piglet, a lamb, or a calf
EP0237956B1 (en) Method of feeding ketoisocaproate to lactating domestic mammals
US10085464B2 (en) Semi-solid animal feed blocks and method of making and using same
WO2001024641A1 (en) Method of increasing feed intake
JPS6368046A (en) Preparation for animal
JP3116506B2 (en) Methods for increasing rumen microbial communities and improving livestock technology
WO2001049128A1 (en) Dietary supplement
JP2002045122A (en) Feed for livestock
IE903685A1 (en) Feedstuffs
US20230413879A1 (en) Food comprising isosteviol and uses thereof
Farrell et al. Effects on growth rate and utilisation of amino acids in weaner pigs fed diets containing whole proteins and free amino acids in combination with different energy sources
Ahn et al. Effect of nonfiber carbohydrate and crude protein levels in the formula of feed on in vitro rumen fermentation characteristics and growth performance of weaned Hanwoo calves
Hindle et al. Effect of the isopropylester of the hydroxylated analogue of methionin (HMBi) on feed intake and performance of dairy cows in early lactation.
Ružić-Muslić et al. Undegradable protein: Important factor in balancing of diets for fattening lambs

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase