WO2001022957A3 - Utilisation de gangliosides et d'autres substances aux fins de modulation de microdomaines sphingolipide-cholesterine - Google Patents

Utilisation de gangliosides et d'autres substances aux fins de modulation de microdomaines sphingolipide-cholesterine Download PDF

Info

Publication number
WO2001022957A3
WO2001022957A3 PCT/EP2000/009588 EP0009588W WO0122957A3 WO 2001022957 A3 WO2001022957 A3 WO 2001022957A3 EP 0009588 W EP0009588 W EP 0009588W WO 0122957 A3 WO0122957 A3 WO 0122957A3
Authority
WO
WIPO (PCT)
Prior art keywords
gangliosides
substances
sphingolipid
cholesterol microdomains
modulating
Prior art date
Application number
PCT/EP2000/009588
Other languages
German (de)
English (en)
Other versions
WO2001022957A2 (fr
Inventor
Mikael Simons
Tim Friedrichson
Kai Simons
Teymuras Kurzchalia
Original Assignee
Max Planck Gesellschaft
Mikael Simons
Tim Friedrichson
Kai Simons
Teymuras Kurzchalia
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Max Planck Gesellschaft, Mikael Simons, Tim Friedrichson, Kai Simons, Teymuras Kurzchalia filed Critical Max Planck Gesellschaft
Priority to CA002385967A priority Critical patent/CA2385967A1/fr
Priority to EP00964258A priority patent/EP1253914A2/fr
Publication of WO2001022957A2 publication Critical patent/WO2001022957A2/fr
Publication of WO2001022957A3 publication Critical patent/WO2001022957A3/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7028Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages
    • A61K31/7032Compounds having saccharide radicals attached to non-saccharide compounds by glycosidic linkages attached to a polyol, i.e. compounds having two or more free or esterified hydroxy groups, including the hydroxy group involved in the glycosidic linkage, e.g. monoglucosyldiacylglycerides, lactobionic acid, gangliosides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/56Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Saccharide Compounds (AREA)

Abstract

L'invention concerne l'utilisation de gangliosides et d'autres substances afin de produire un produit de modulation de microdomaines sphingolipide-cholesterine.
PCT/EP2000/009588 1999-09-29 2000-09-29 Utilisation de gangliosides et d'autres substances aux fins de modulation de microdomaines sphingolipide-cholesterine WO2001022957A2 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
CA002385967A CA2385967A1 (fr) 1999-09-29 2000-09-29 Utilisation de derives du cholesterol pour moduler les microdomaines sphingolipides-cholesterol
EP00964258A EP1253914A2 (fr) 1999-09-29 2000-09-29 Utilisation de gangliosides et d'autres substances aux fins de modulation de microdomaines sphingolipide-cholesterine

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19946737.4 1999-09-29
DE1999146737 DE19946737A1 (de) 1999-09-29 1999-09-29 Verwendung von Gangliosiden zur Modulation von Sphingolipid-Cholesterin-Mikrodomänen

Publications (2)

Publication Number Publication Date
WO2001022957A2 WO2001022957A2 (fr) 2001-04-05
WO2001022957A3 true WO2001022957A3 (fr) 2002-06-27

Family

ID=7923754

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/009588 WO2001022957A2 (fr) 1999-09-29 2000-09-29 Utilisation de gangliosides et d'autres substances aux fins de modulation de microdomaines sphingolipide-cholesterine

Country Status (4)

Country Link
EP (1) EP1253914A2 (fr)
CA (1) CA2385967A1 (fr)
DE (1) DE19946737A1 (fr)
WO (1) WO2001022957A2 (fr)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0321228D0 (en) * 2003-09-10 2003-10-08 Inpharmatica Ltd Modulating cell activity
JP2008504330A (ja) 2004-06-29 2008-02-14 ヤド テクノロジーズ ゲゼルシャフト ミット ベシュレンクテル ハフツング スフィンゴ脂質由来医薬組成物
CN111422870B (zh) * 2020-04-15 2021-04-09 浙江博瑞电子科技有限公司 一种hf电子气体深度纯化材料的制备及应用方法

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0470558A (ja) * 1990-07-11 1992-03-05 Yamaguchi Pref Gov エタノールセンサー
WO1994001102A1 (fr) * 1992-06-30 1994-01-20 Legomer Partners, L.P. Molecules contenant des aminimides et materiaux utilises comme agents de reconnaissance moleculaire
JPH08256977A (ja) * 1995-03-22 1996-10-08 Olympus Optical Co Ltd 内視鏡装置
DE19643585A1 (de) * 1996-10-22 1998-04-23 Beiersdorf Ag Antiadhäsive Sphingolipide
US5914127A (en) * 1995-09-08 1999-06-22 Beth Israel Deaconess Medical Center Isolation and uses of caveolae

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0470558A (ja) * 1990-07-11 1992-03-05 Yamaguchi Pref Gov エタノールセンサー
WO1994001102A1 (fr) * 1992-06-30 1994-01-20 Legomer Partners, L.P. Molecules contenant des aminimides et materiaux utilises comme agents de reconnaissance moleculaire
JPH08256977A (ja) * 1995-03-22 1996-10-08 Olympus Optical Co Ltd 内視鏡装置
US5914127A (en) * 1995-09-08 1999-06-22 Beth Israel Deaconess Medical Center Isolation and uses of caveolae
DE19643585A1 (de) * 1996-10-22 1998-04-23 Beiersdorf Ag Antiadhäsive Sphingolipide

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 016, no. 272 (P - 1373) 18 June 1992 (1992-06-18) *
PATENT ABSTRACTS OF JAPAN vol. 1997, no. 02 28 February 1997 (1997-02-28) *

Also Published As

Publication number Publication date
CA2385967A1 (fr) 2001-04-05
WO2001022957A2 (fr) 2001-04-05
DE19946737A1 (de) 2001-04-19
EP1253914A2 (fr) 2002-11-06

Similar Documents

Publication Publication Date Title
AU3136897A (en) Compositions, methods and devices for the transdermal delivery of drugs
HK1039942A1 (en) Piperdines as ccr5 modulators.
ZA981132B (en) Methods, compositions and articles for reducing or preventing the effects of inflammation.
WO2000066104A3 (fr) Composes inhibant ace-2 et leurs procedes d'utilisation
AU3276897A (en) Dioxane derivatives, liquid-crystal compositions containing the same, and liquid-crystal display devices made by using the same
AU3813499A (en) The use of dihydropyrimidines as medicaments, and novel substances
AU9757398A (en) Novel compounds derived from menthol and use as refreshing agent
AU4180696A (en) Functionalized polyorganosiloxanes and one of the processes for the preparation thereof
AU2615997A (en) Fragrance precursors
AU2001294190A1 (en) Gas-generating agent composition and gas generator employing the same
AU5372096A (en) Detergent compositions containing fragrance precursors and the fragrance precursors themselves
AU9313198A (en) Gas generant compositions, methods of production of the same and devices made therefrom
ID20137A (id) Turunan propanolamina, proses pembuatannya, sediaan farmasi yang mengandung senyawa ini, dan penggunannya
HK1036974A1 (en) Indole derivatives and medicinal compositions containing the same.
AU2035401A (en) Lubricant combination and process for the preparation thereof
AU1238900A (en) Speckle particles and compositions containing the speckle particles
AU7853700A (en) Foams and compositions containing these foams
AU3527695A (en) Gp130 lacking the transmembrane domain
AU7688098A (en) Fadd-like anti-apoptotic molecules, methods of using the same, and compositions for and methods of making the same
WO2001022957A3 (fr) Utilisation de gangliosides et d'autres substances aux fins de modulation de microdomaines sphingolipide-cholesterine
AU7595298A (en) Azolidinediones useful for the treatment of diabetes, dyslipidemia and hy pertension
HK1007867A1 (en) Gel cleanser composition.
AU5494298A (en) Pharmaceutical compositions for the treatment of the eye
WO1999033451A3 (fr) Melange et composition pharmaceutique comprenant du z-4- hydroxytamoxifene et de la cyclodextrine
AU7675198A (en) Sucralfate-containing composition and process for the preparation thereof

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
WWE Wipo information: entry into national phase

Ref document number: 2000964258

Country of ref document: EP

WWE Wipo information: entry into national phase

Ref document number: 2385967

Country of ref document: CA

AK Designated states

Kind code of ref document: A3

Designated state(s): CA JP US

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

WWP Wipo information: published in national office

Ref document number: 2000964258

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

WWR Wipo information: refused in national office

Ref document number: 2000964258

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 2000964258

Country of ref document: EP