WO2001022915A3 - Process for production of cis-dichloro-(trans-1-1,2-cyclohexanediamine)platinum(ii) - Google Patents

Process for production of cis-dichloro-(trans-1-1,2-cyclohexanediamine)platinum(ii) Download PDF

Info

Publication number
WO2001022915A3
WO2001022915A3 PCT/CZ2000/000070 CZ0000070W WO0122915A3 WO 2001022915 A3 WO2001022915 A3 WO 2001022915A3 CZ 0000070 W CZ0000070 W CZ 0000070W WO 0122915 A3 WO0122915 A3 WO 0122915A3
Authority
WO
WIPO (PCT)
Prior art keywords
trans
cyclohexanediamine
dichloro
cis
platinum
Prior art date
Application number
PCT/CZ2000/000070
Other languages
French (fr)
Other versions
WO2001022915A2 (en
Inventor
Frantisek Zak
Anna Poulova
Original Assignee
Pliva Lachema As
Frantisek Zak
Anna Poulova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pliva Lachema As, Frantisek Zak, Anna Poulova filed Critical Pliva Lachema As
Priority to AU72673/00A priority Critical patent/AU7267300A/en
Publication of WO2001022915A2 publication Critical patent/WO2001022915A2/en
Publication of WO2001022915A3 publication Critical patent/WO2001022915A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
    • C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
    • C07F15/0086—Platinum compounds
    • C07F15/0093—Platinum compounds without a metal-carbon linkage

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)

Abstract

A process for production of cis-dichloro-(trans-1-1,2-cyclohexanediamine)platinum(II) complex, based on treatment of 1 mol of alkali metal tetrachloroplatinate(II) in an aqueous solution with 0.9 to 1.7 mol of trans-1-1,2-cyclohexanediammonium tartrate at pH of the reaction mixture between 7 and 12 obtained by alkalinisation by an alkali metal hydroxide, followed by separation of the solid product from the aqueous reaction medium.
PCT/CZ2000/000070 1999-09-29 2000-09-22 Process for production of cis-dichloro-(trans-1-1,2-cyclohexanediamine)platinum(ii) WO2001022915A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU72673/00A AU7267300A (en) 1999-09-29 2000-09-22 Process for production of cis-dichloro-(trans-1-1,2-cyclohexanediamine)platinum(ii)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CZ19993458A CZ294382B6 (en) 1999-09-29 1999-09-29 Process for preparing cis-dichloro-(trans-l-1,2-cyclohexanediamine)platinum complex
CZPV1999-3458 1999-09-29

Publications (2)

Publication Number Publication Date
WO2001022915A2 WO2001022915A2 (en) 2001-04-05
WO2001022915A3 true WO2001022915A3 (en) 2001-10-25

Family

ID=5466775

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CZ2000/000070 WO2001022915A2 (en) 1999-09-29 2000-09-22 Process for production of cis-dichloro-(trans-1-1,2-cyclohexanediamine)platinum(ii)

Country Status (3)

Country Link
AU (1) AU7267300A (en)
CZ (1) CZ294382B6 (en)
WO (1) WO2001022915A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN104945443A (en) * 2015-07-23 2015-09-30 青岛蓝盛洋医药生物科技有限责任公司 Drug, namely oxaliplatin compound, for treating cancer
CN104940151A (en) * 2015-07-23 2015-09-30 青岛蓝盛洋医药生物科技有限责任公司 Oxaliplatin freeze-dried powder injection composition as anti-cancer drug

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558469A1 (en) * 1984-01-25 1985-07-26 Bellon Labor Sa Roger New coordination compounds of platinum, processes for producing them and their use as medicinal products
EP0154589A2 (en) * 1984-03-01 1985-09-11 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce New antineoplastic platinum (IV) complexes
US4658047A (en) * 1985-09-27 1987-04-14 The United States Of America As Represented By The Department Of Health And Human Services Method of preparing 1,2-diaminocyclohexane tetrachloro platinum (IV) isomers
JPH03131529A (en) * 1989-10-13 1991-06-05 Tanaka Kikinzoku Kogyo Kk Production of potassium tetrachloroplatinate

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558469A1 (en) * 1984-01-25 1985-07-26 Bellon Labor Sa Roger New coordination compounds of platinum, processes for producing them and their use as medicinal products
EP0154589A2 (en) * 1984-03-01 1985-09-11 THE UNITED STATES OF AMERICA as represented by the Secretary United States Department of Commerce New antineoplastic platinum (IV) complexes
US4658047A (en) * 1985-09-27 1987-04-14 The United States Of America As Represented By The Department Of Health And Human Services Method of preparing 1,2-diaminocyclohexane tetrachloro platinum (IV) isomers
JPH03131529A (en) * 1989-10-13 1991-06-05 Tanaka Kikinzoku Kogyo Kk Production of potassium tetrachloroplatinate

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 015, no. 341 (C - 0863) 29 August 1991 (1991-08-29) *

Also Published As

Publication number Publication date
CZ9903458A3 (en) 2001-05-16
WO2001022915A2 (en) 2001-04-05
AU7267300A (en) 2001-04-30
CZ294382B6 (en) 2004-12-15

Similar Documents

Publication Publication Date Title
JOP20180046A1 (en) Aqueous iron carbohydrate complexes, their production and medicaments containing them
AU6727396A (en) Method for manufacturing cobalt catalysts
WO2005000210A3 (en) Synthesis of high molecular weight iron-saccharidic complexes
EP0373578A3 (en) Catalyst recovery
WO2001074487A1 (en) Method of separating imide compound
EP1614659A3 (en) Titanium oxide production process
CA2275866A1 (en) Process for making glyphosate by oxidizing n-substituted glyphosates
IE45926L (en) Hydrolysis of an ó-aminonitrile
MY122894A (en) Purification of onium hydroxides by electrodialysis
WO2001022915A3 (en) Process for production of cis-dichloro-(trans-1-1,2-cyclohexanediamine)platinum(ii)
CA2103480A1 (en) A process for the production of pure nickel hydroxide and its use
MA23229A1 (en) PROCESS FOR THE PRODUCTION OF N-PHOSPHONOMETHYLGLYCIN AND ITS SALTS.
RU94043800A (en) Process for preparing difficultly soluble metal hydroxides
EP1266883A4 (en) Process for producing aromatic carbonate
AU1163195A (en) Process for recovering and re-using cobalt and tungsten from reaction liquors
AU7549998A (en) Process for producing 3-alkenylcephem compounds
CA2285573A1 (en) A method for stimulating red blood cell production
WO2002010286A3 (en) Process for the preparation of carboxylate and phosphonate ruthenium polypyridine dyes and a process for the preparation of reaction intermediates used in such process
CA2121059A1 (en) Processing aid for paper making
CA2067382A1 (en) Production of glyoxylic acid from glycolic acid
CA2280511A1 (en) Production of 1,3-diaminopentane by hydrogenation of 3-aminopentanenitrile
EP1365023A4 (en) Dna encoding novel d-aminoacylase and process for producing d-amino acid by using the same
CA2162215A1 (en) Process for the preparation of manganese(iii)-containing nickel hydroxide
CA2222119A1 (en) Process for the production of ruthenium (iii) acetate solution
WO2002072723A3 (en) Gelatin manufacturing process and product

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: A3

Designated state(s): AE AG AL AM AT AU AZ BA BB BG BR BY BZ CA CH CN CR CU CZ DE DK DM DZ EE ES FI GB GD GE GH GM HR HU ID IL IN IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MA MD MG MK MN MW MX MZ NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT TZ UA UG US UZ VN YU ZA ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW MZ SD SL SZ TZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

122 Ep: pct application non-entry in european phase
NENP Non-entry into the national phase

Ref country code: JP