WO2001021806A1 - Antigenes anti-chlamydia, fragments d'adn correspondants et leurs utilisations - Google Patents

Antigenes anti-chlamydia, fragments d'adn correspondants et leurs utilisations Download PDF

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Publication number
WO2001021806A1
WO2001021806A1 PCT/CA2000/001090 CA0001090W WO0121806A1 WO 2001021806 A1 WO2001021806 A1 WO 2001021806A1 CA 0001090 W CA0001090 W CA 0001090W WO 0121806 A1 WO0121806 A1 WO 0121806A1
Authority
WO
WIPO (PCT)
Prior art keywords
polypeptide
nucleic acid
chlamydia
vaccine
sequence
Prior art date
Application number
PCT/CA2000/001090
Other languages
English (en)
Other versions
WO2001021806B1 (fr
Inventor
Andrew D. Murdin
Raymond P. Oomen
Joe Wang
Pamela Dunn
Original Assignee
Aventis Pasteur Limited
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pasteur Limited filed Critical Aventis Pasteur Limited
Priority to AU73987/00A priority Critical patent/AU7398700A/en
Publication of WO2001021806A1 publication Critical patent/WO2001021806A1/fr
Publication of WO2001021806B1 publication Critical patent/WO2001021806B1/fr

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/295Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Chlamydiales (O)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Abstract

La présente invention concerne un procédé d'immunisation d'un hôte, y compris l'être humain, basé sur l'acide nucléique, y compris l'ADN, contre une maladie provoquée par l'infection par une souche de Chlamydia, plus particulièrement C. pneumoniae, utilisant un vecteur contenant une séquence nucléotidique codant pour un hypothétique inhibiteur de l'apoptose d'une souche de Chlamydia pneumoniae, ainsi qu'un promoteur pour réaliser l'expression du gène inhibiteur hypothétique de l'apoptose chez l'hôte. Des modifications sont envisageables dans le cadre de l'invention.
PCT/CA2000/001090 1999-09-17 2000-09-15 Antigenes anti-chlamydia, fragments d'adn correspondants et leurs utilisations WO2001021806A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU73987/00A AU7398700A (en) 1999-09-17 2000-09-15 Chlamydia antigens and corresponding dna fragments and uses thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US15432499P 1999-09-17 1999-09-17
US60/154,324 1999-09-17

Publications (2)

Publication Number Publication Date
WO2001021806A1 true WO2001021806A1 (fr) 2001-03-29
WO2001021806B1 WO2001021806B1 (fr) 2001-05-10

Family

ID=22550895

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/CA2000/001090 WO2001021806A1 (fr) 1999-09-17 2000-09-15 Antigenes anti-chlamydia, fragments d'adn correspondants et leurs utilisations

Country Status (2)

Country Link
AU (1) AU7398700A (fr)
WO (1) WO2001021806A1 (fr)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999027105A2 (fr) * 1997-11-21 1999-06-03 Genset Sequence genomique et polypeptides de chlamydia pneumoniae, leurs fragments et leurs utilisations, en particulier pour le diagnostic, la prevention ou le traitement d'une infection

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999027105A2 (fr) * 1997-11-21 1999-06-03 Genset Sequence genomique et polypeptides de chlamydia pneumoniae, leurs fragments et leurs utilisations, en particulier pour le diagnostic, la prevention ou le traitement d'une infection

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
DATABASE SWALL EBI; 1 May 1999 (1999-05-01), "CT863 Hypothetical Protein", XP002157698 *
FAN, T. ET AL.: "Inhibition of apoptosis in Chlamydia-infected cells: blockade of mitochondrial cytochrome c release and caspase activation.", J. EXP. MED., vol. 187, no. 4, 1998, pages 487 - 496, XP000978902 *

Also Published As

Publication number Publication date
WO2001021806B1 (fr) 2001-05-10
AU7398700A (en) 2001-04-24

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