WO2001021109A9 - Differentially expanding stent and methods of use - Google Patents
Differentially expanding stent and methods of useInfo
- Publication number
- WO2001021109A9 WO2001021109A9 PCT/US2000/026378 US0026378W WO0121109A9 WO 2001021109 A9 WO2001021109 A9 WO 2001021109A9 US 0026378 W US0026378 W US 0026378W WO 0121109 A9 WO0121109 A9 WO 0121109A9
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- stent
- pressure
- tubular wall
- makeup
- expand
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/856—Single tubular stent with a side portal passage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/95—Instruments specially adapted for placement or removal of stents or stent-grafts
- A61F2/958—Inflatable balloons for placing stents or stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0018—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in elasticity, stiffness or compressibility
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0014—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis
- A61F2250/0039—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof having different values of a given property or geometrical feature, e.g. mechanical property or material property, at different locations within the same prosthesis differing in diameter
Definitions
- the present invention relates to stents, stent systems and methods for delivery and use thereof.
- a type of endoprosthesis device may be placed or implanted within a vein, artery or other hollow body organ or lumen for treating occlusions, stenoses, or aneurysms of a vessel by reinforcing the wall of the vessel or by expanding the vessel.
- Stents have been used to treat dissections in blood vessel walls caused by balloon angioplasty of the coronary arteries as well as peripheral arteries and to improve angioplasty results by preventing elastic recoil and remodeling of the vessel wall.
- stent as used in this Application is a device which is intraluminally implanted within bodily vessels to reinforce collapsing, dissected, partially occluded, weakened, diseased or abnormally dilated or small segments of a vessel wall.
- One of the drawbacks of conventional stents is that they are difficult to position.
- positiomng a stent involves moving the stent to the desired position and then maintaining the position while the stent is deployed. Accurate positioning is critical to proper operation of the stent.
- stents For example, the use of such stents to treat diseased vessels at or near a bifurcation (branch point) of a vessel requires very accurate positioning otherwise, there is a potential for compromising the degree of patency of the main vessel and/or its branches, or the bifurcation point. Compromising the bifurcation point limits the ability to insert a branch stent into the side branch if the result of treatment of the main vessel is suboptimal. Suboptimal results may occur as a result of several mechanisms, such as displacing diseased tissue, plaque shifting, vessel spasm, dissection with or without intimal flaps, thrombosis, and embolism.
- the invention provides methods and apparatus for ensuring accurate positioning of a stent in a body lumen.
- the invention provides for accurate positioning of a stent near a vessel bifurcation such that a side hole in the stent aligns with the ostium of a branch vessel.
- the invention also provides techniques for accurately positioning a stent near a critical area of a body lumen, such as a diseased portion of a vessel wall.
- a stent comprises an expandable tubular wall comprising first and second portions.
- the first portion comprises a first makeup with a corresponding expansion factor and the second portion comprises a second makeup with a corresponding expansion factor.
- the first and second makeups provide a predetermined sequence of expansion for the stent.
- the predetermined sequence includes expansion of the first portion prior to the second portion.
- the first makeup is a material formed into a particular geometry.
- the geometry may include a zigzag geometry, an S-curve geometry, an undulating geometry, and the like.
- the geometry of the first makeup is a zigzag geometry while the geometry of the second makeup is an S-curve geometry.
- an expander is at least partially disposed within an area defined by the expandable tubular wall of the stent.
- the expander is operable to apply pressure on the expandable tubular wall.
- the expander is a balloon.
- the stent further comprises a third portion adjacent to the first portion and spaced apart from the second portion. The third portion has the second makeup such that the second and third portions have about the same expansion factor.
- the first portion expands more rapidly than the second and third portions when the first, second and third portions are subjected to a steadily increasing pressure.
- the increasing pressure is an increasing radial pressure.
- a method comprises providing a stent including a tubular wall.
- the tubular wall comprises both a first and second portion.
- the first portion is adapted to expand in response to a first pressure
- the second portion is adapted to expand in response to a second pressure.
- the stent is positioned in the body lumen.
- the tubular wall is subjected to a first pressure, wherein the first portion expands more than the second portion.
- the tubular wall is then subjected to a second pressure greater than the first pressure, to fully expand the stent.
- the stent includes a side hole, and positioning the stent includes positioning the side hole adjacent to a bifurcation in the body lumen.
- an expander is provided for subjecting the tubular wall to a desired pressure.
- Fig. 1 is an overall view of a stent according to an embodiment of the present invention, the stent illustrated in a collapsed orientation;
- Figs. 2A, 3 A and 4A depict overall views of a portion of individual struts for use in the present invention
- Fig. 2B, 3B and 4B illustrate patterns of struts made up of the struts shown in Figs. 2A, 3 A and 4A, respectively, used to form a portion of the stent shown in Fig. 1;
- FIG. 5 illustrates an interface between strut patterns forming a portion of the stent illustrated in Fig. 1 ;
- Fig. 6 depicts an overall view of the stent of Fig. 1 in a partially deployed orientation;
- Fig. 7 depicts an overall view of the stent of Fig. 1 in a fully deployed orientation
- Fig. 8 depicts an overall view of a stent according to an alternative embodiment of the present invention.
- Fig. 9 shows a kit including a stent and instructions for use according to the present invention.
- the present invention provides methods and apparatus for maintaining stent position during deployment.
- the methods and apparatus may be used to assure alignment of a side hole in a stent with the ostium of a branch vessel. Further, the methods and apparatus may be used to control cell distribution during stent deployment.
- Applications of the invention include use in relation to hollow organs or body lumens including, among others, the cardiac, coronary, carotid artery, renal, peripheral vascular, gastrointestinal, pulmonary, urinary and neurovascular systems and the brain.
- a stent according to the present invention is positioned within a body lumen and subsequently deployed.
- the stent Upon deployment, the stent is expanded to where it contacts, and even supports or expands the body lumen such as a vascular wall. As the stent contacts the wall, it causes cells of the wall to re-distribute at the contact point. For example, when the stent is expanded, the vascular wall may stretch, causing cell density in the stretched area to decrease. Alternatively, both ends of the stent can expand more rapidly than a midsection resulting in a higher cell density near the midsection than would be achieved if all portions of the stent expanded simultaneously. Thus, the present invention advantageously provides for control of cell re-distribution during stent deployment. This control may result in more uniform and even distribution of cell structure.
- the stent often shifts position as it contacts the body lumen, such as the vascular wall.
- a stent may first contact the body lumen wall at the distal end of the stent. This contact can push the stent such that the position of the stent midsection shifts from a pre-deployment position. This stent shift is inimical to proper stent positioning.
- a stent In one application, a stent must be positioned in a vessel near a bifurcation such that a side hole in the stent midsection aligns with an ostium of a branch vessel.
- stent shift can cause the stent midsection to shift which would cause a misalignment between the side hole and the ostium. This misalignment can reduce the patency or even occlude the ostium.
- the invention provides for a stent which expands more rapidly at the midsection than at the proximal and distal ends. This differential expansion causes the stent to initially contact the vessel at the vessel bifurcation. By initially contacting the vessel at the bifurcation, the magnitude of stent shift relative to the bifurcation is significantly reduced and the side hole and ostium remain aligned.
- stents can be designed to sequentially deploy such that any number of lumen areas, or critical portions, are contacted first or in a prescribed sequence. Accordingly, other advantages of the invention include, but are not limited to, providing contact with a lesion or diseased area prior to contact with surrounding healthy areas during stent deployment. Alternatively, initial contact with healthy areas followed by contact with diseased areas can be provided during stent deployment.
- the differential stent according to the present invention can be applied in a number of ways. Depending upon the lesion, calcification, vessel narrowing, vessel morphology, and other considerations, the stent may be comprised of any number of sections that expand at different rates. Further, expansion of a stent according to the present invention can be differential and/or multi-directional. Multidirectional stent expansion minimizes foreshortening of the stent. Referring now to Fig. 1, one embodiment of stent 10 according to the present invention will be described. Stent 10 includes a midsection 20, a proximal portion 22, and a distal portion 24.
- a distal interface 86 exists at a junction of distal portion 24 and midsection 20, and a proximal interface 87 exists at a junction of proximal portion 22 and midsection 20. It will be appreciated by those skilled in the art that the relative sizes of distal portion 24, midsection 20 and proximal portion 22 may vary within the scope of the present invention from that shown. Further, interfaces 86 and 87 may have a non-linear or other configuration than shown.
- Midsection 20 includes a side hole 11.
- side hole 11 refers to a relatively large hole which is intended to be aligned with the ostium of a branch vessel.
- Side hole 11 is separate from, and larger than, any of the multiple passageways extending through the side of stent 10 between struts in the stent geometry.
- side hole 11 is defined by a band of continuous material which defines the perimeter of side hole 11. This continuous band of material preferably comprises discontinuities over its length so that the area of side hole 11 expands together with the expansion of stent 10.
- the continuous band comprises protrusions which project inwardly from a peripheral edge of side hole 11.
- these protrusions are initially aligned within a cylindrical envelope of the tubular body of stent 10.
- stent 10 is formed without side hole 11.
- side hole 11 is unnecessary, or undesirable.
- stent 10 is provided without side hole 11.
- a makeup of midsection 20, proximal portion 22, and distal portion 24 includes a plurality of struts formed in particular geometries and/or with particular materials.
- a combination of geometry and material can be chosen to produced a desired expansion factor.
- the expansion factor includes a propensity to expand when a particular pressure is applied to the strut.
- the expansion factor includes a proclivity to expand where no pressure is applied to the strut, such as when stent 10 is released from a sheath.
- stent 10 is designed to expand in a predetermined sequence during deployment.
- distal portion 24 can expand before or simultaneous with proximal portion 22, which in turn can expand before midsection 20.
- This predetermined expansion sequence can occur, for example, under application of a steadily increasing pressure.
- Any apparatus capable of applying a generally equal pressure to midsection 20, proximal portion 24 and distal portion 22 can be used.
- the apparatus for applying pressure is a balloon 30.
- stent 10 expands differentially when released from a sheath or other restraining device. In this manner, stent 10 expansion factors control the differential expansion of stent portions 20, 22 and 24.
- stent delivery system may employ a moveable or non-moveable side sheath or side member as further described in U.S. App. Serial No. (Attorney Docket No. 19601-
- one embodiment of the referenced application provides an embodiment where a catheter system facilitates placement of the stent within the main vessel, with the side hole being in registry with an ostium of a branch vessel. This placement may be accomplished, for example, by advancing a main vessel guidewire in the main vessel until passing the branch vessel. The catheter is then advanced over the main vessel guidewire until the stent reaches or is proximal to the branch vessel. At this point, a branch vessel guidewire may be introduced through the branch vessel lumen of the catheter.
- the branch vessel guidewire is advanced out of the catheter and into the branch vessel to assist in aligning the side hole with the ostium of the branch vessel prior to deployment of the stent in the main vessel.
- the catheter may taper at a point to a narrow distal end, which may also be curved slightly outwardly.
- One advantage of such a catheter system is that a single guidewire may be used to introduce the catheter. Once introduced, the catheter serves as a guide for the branch vessel guidewire.
- Alignment of the side hole with the ostium can be accomplished in a variety of ways.
- introduction of the branch vessel guidewire into the branch vessel may sufficiently align the side hole with the ostium.
- Other alignment techniques may depend on the configuration of the catheter.
- the catheter may comprise a flexible sheath that is movably coupled to the catheter body, e.g., by passing through a lumen of a truncated connector that is coupled to the catheter body.
- the sheath may be advanced into the branch vessel to move the side hole into registry with the ostium.
- struts are comprised of geometries of varying lengths, widths, and shape.
- Shapes can include, but are not limited to, angled, hook shaped, or S-curved shapes. Additionally, geometries can include differing densities of struts per surface area. Materials used to form the struts can include, but are not limited to, stainles steel, Nitinol, and the like.
- Figs. 2B, 3B and 4B illustrate strut embodiments in accordance with the present invention.
- the strut geometries illustrated in Figs. 2B, 3B and 4B expand at a predetermined pressure. While these Figs, show exemplary embodiments of strut geometries, it should be recognized that many geometries are possible in accordance with the present invention.
- alternative geometries can include struts which expand only at a particular pressure, which expand at a rate related to a particular pressure, or which expand at a particular rate without application of pressure.
- strut 55 is adapted to expand when subjected to a pressure that is about four (4) atmospheres (ATM).
- the geometry and material of strut 55 includes a rectangular-shaped filament 59, with dimensions 58 of about 0.004 inches by 0.005 inches, and made of stainless steel.
- Filament 59 is formed in a zigzag pattern with a length 56 and a curve 57. In one embodiment, length 56 is about 0.04 inches and the radius of curvature of curve 57 is about 0.005 inches.
- strut 55 expands at between two (2) and eight (8) ATM. It should be appreciated by one skilled in the art that other expansion presures are also possible.
- Fig. 2B illustrates an embodiment of a structure portion 50 formed by combining a plurality of struts 55.
- strut 65 is adapted to expand when subjected to a pressure that is about three (3) ATM.
- the geometry and material of strut 65 includes a rectangular-shaped filament 69 with dimensions 68 of about 0.004 inches by 0.005 inches, and made of stainless steel. Filament 69 is formed in an S-curved pattern with a length 66 and a curve 67. In one embodiment, length 66 is about 0.050 inches and curve 67 has a radius of curvature of about 0.005 inches. It will be appreciated by those skilled in the art that the pressure at which strut 65 expands will depend, in part, on the geometry, thickness and materials of strut 65.
- strut 65 geometry, thickness and materials of strut 65 are adjusted so that strut 65 expands at between two (2) and eight (8) ATM. It should be appreciated by one skilled in the art that other expansion presures are also possible.
- Fig. 3B illustrates an embodiment of a structure portion 60 formed by combining a number of the struts 65.
- strut 75 is adapted to expand when subjected to a pressure that is about five (5) ATM.
- the geometry and material of strut 75 includes a rectangular-shaped filament 79 with dimensions 78 of about 0.003 inches by 0.005 inches, and made of stainless steel.
- Filament 79 is formed in a undulating pattern with a primary length 76, a secondary length 57, a first width 71, and a second width 72.
- primary length 76 is about 0.020 inches and secondary length 77 is about 0.014 inches.
- First 71 and second 72 widths are about 0.006 inches and 0.009 inches, respectively.
- strut 75 expands at between two (2) and ten (10) ATM. It should be appreciated by one skilled in the art that other expansion presures are also possible.
- Fig. 4B illustrates an embodiment of a structure portion 70 formed by combining a number of the struts 75.
- strut 55 is adjusted such that strut 55 expands at about eight (8) ATM, a similar adjustment of struts 65 and 75 would yield expansion pressures of about six (6) ATM and about ten (10) ATM, respectively.
- proximal portion 22 and distal portion 24 are formed of struts 55 interconnected as in structure portion 50.
- Midsection 20 is formed of struts 65 interconnected as in structure portion 60. Since struts 65 expand when subjected to a first pressure (e.g., 3 ATM) and struts 55 expand under a greater second pressure (e.g., 4 ATM) midsection 20 will expand before proximal 22 and distal 24 portions when stent 10 is subjected to a steadily increasing pressure. Alternatively, expansion pressure is increased by a step-function or other pattern.
- a first pressure e.g. 3 ATM
- second pressure e.g. 4 ATM
- struts 55 are interconnected with struts 65.
- proximal interface 87 an embodiment of proximal interface 87 is illustrated in greater detail.
- a structure portion 80 includes a portion 82 of midsection 20 and a portion 84 of proximal portion 22 joined at proximal interface 87.
- Portion 82 of midsection 20 is formed of struts 65 while portion 84 of proximal portion 22 is formed of struts 55.
- a method of operating stent 10 is further described in relation to Figs. 6 and 7. Referring to Fig. 6, stent 10 is shown in a partially deployed orientation.
- Stent 10 includes midsection 20 which expands at a lower pressure than either proximal portion 22 or distal portion 24. Partial deployment involves, in one embodiment, partially inflating balloon 30. As balloon 30 is inflated, it exerts pressure on the inner wall of stent 10 at midsection 20, proximal portion 22, and distal portion 24. Because midsection 20 expands at a lower pressure than either proximal portion 22 or distal portion 24, midsection 20 expands more fully and/or more rapidly. Thus, a cross-sectional area of midsection 20 is greater than a cross-sectional area of either proximal portion 22 or distal portion 24 when stent 10 is partially expanded. Stent 10 is shown fully deployed in Fig. 7.
- proximal portion 22 and distal portion 24 fully expand.
- the cross-sectional areas of midsection 20, proximal portion 22 and the distal portion 24 are generally equal and cylindrical.
- stent 10 can be formed with any combination of struts to achieve a desired expansion sequence.
- stent 10 is formed using struts 75 at midsection 20 and struts 65 at proximal portion 22 and distal portion 24.
- struts 75 at midsection 20
- struts 65 at proximal portion 22 and distal portion 24.
- stent 10 has two portions, with a two step expansion used to fully expand the two portions, h yet another embodiment, stent 10 is formed using struts 75 for distal portion 24, struts 65 for proximal portion 22, and struts 55 for midsection 20.
- midsection 20 will expand slower than either proximal portion 22 or distal portion 24. Additionally, distal portion 24 will expand more rapidly than proximal portion 22.
- stent 10 can comprise any number of expansion sections, including fewer or a greater number of stent portions than depicted in Figs. 1-7.
- Fig. 8 illustrates stent 10 comprising twenty expansion sections 125 individually delineated as sections 101, 102, 103, 104, 105, 106, 107, 108, 109, 110, 111, 112, 113, 114, 115, 116, 117, 118, 119, 120.
- Expansion sections 125 can be formed using different geometries and/ or different materials to create a variety of expansion sequences.
- expansion sections 125 are designed to deploy at different pressures such that stent 10 expands first at section 101, then 102, then 103, and continue in order until stent 10 is fully deployed.
- stent 10 is designed to deploy first at section 120, then 119, then 118, and continue in order until stent 10 is fully deployed.
- stent 10 can be designed such that section 110 expands, then sections 109 and 111 expand simultaneously, then sections 108 and 112 expand simultaneously, and continue in that pattern until stent 10 is fully deployed.
- Those skilled in the art will appreciate that other expansion patterns also fall within the scope of the present invention.
- Kit 140 includes instructions for use 142 which set forth various procedures for deploying stent 10 using any of the techniques previously described. Instructions for use may be in written or machine readable form.
- kit 140 comprises stent 10 crimped over balloon 30 (not shown).
- kit 140 may alternatively include any of the other elements described herein, such as other devices for exerting desired pressure on expandable stent 10, stent delivery apparatus and catheters, including the proximal hub thereof.
- instructions 142 may describe use of any of the other elements.
Abstract
Description
Claims
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1020027003827A KR20020064882A (en) | 1999-09-23 | 2000-09-25 | Differentially expanding stent and method of use |
AU77159/00A AU766043B2 (en) | 1999-09-23 | 2000-09-25 | Differentially expanding stent and methods of use |
CA002383304A CA2383304A1 (en) | 1999-09-23 | 2000-09-25 | Differentially expanding stent and methods of use |
IL14865600A IL148656A0 (en) | 1999-09-23 | 2000-09-25 | Differentially expanding stent and methods of use |
JP2001524539A JP2003509158A (en) | 1999-09-23 | 2000-09-25 | Differentially expandable stent and method of use |
NZ517945A NZ517945A (en) | 1999-09-23 | 2000-09-25 | Differentially expanding stent and methods of use |
EP00966878A EP1233722A4 (en) | 1999-09-23 | 2000-09-25 | Differentially expanding stent and methods of use |
HK02108558.5A HK1046843A1 (en) | 1999-09-23 | 2002-11-27 | Differentially expanding stent and methods of use |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US15561199P | 1999-09-23 | 1999-09-23 | |
US60/155,611 | 1999-09-23 | ||
US66868700A | 2000-09-22 | 2000-09-22 | |
US09/668,687 | 2000-09-22 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001021109A1 WO2001021109A1 (en) | 2001-03-29 |
WO2001021109A9 true WO2001021109A9 (en) | 2002-11-21 |
Family
ID=26852457
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/026378 WO2001021109A1 (en) | 1999-09-23 | 2000-09-25 | Differentially expanding stent and methods of use |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP1233722A4 (en) |
JP (1) | JP2003509158A (en) |
KR (1) | KR20020064882A (en) |
CN (1) | CN1391452A (en) |
AU (1) | AU766043B2 (en) |
CA (1) | CA2383304A1 (en) |
HK (1) | HK1046843A1 (en) |
IL (1) | IL148656A0 (en) |
NZ (1) | NZ517945A (en) |
WO (1) | WO2001021109A1 (en) |
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US8858610B2 (en) | 2009-01-19 | 2014-10-14 | W. L. Gore & Associates, Inc. | Forced deployment sequence |
US8876807B2 (en) | 2009-01-19 | 2014-11-04 | W. L. Gore & Associates, Inc. | Forced deployment sequence |
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US9782282B2 (en) | 2011-11-14 | 2017-10-10 | W. L. Gore & Associates, Inc. | External steerable fiber for use in endoluminal deployment of expandable devices |
US9877858B2 (en) | 2011-11-14 | 2018-01-30 | W. L. Gore & Associates, Inc. | External steerable fiber for use in endoluminal deployment of expandable devices |
US9375308B2 (en) | 2012-03-13 | 2016-06-28 | W. L. Gore & Associates, Inc. | External steerable fiber for use in endoluminal deployment of expandable devices |
US11911258B2 (en) | 2013-06-26 | 2024-02-27 | W. L. Gore & Associates, Inc. | Space filling devices |
WO2016183495A2 (en) | 2015-05-14 | 2016-11-17 | W. L. Gore & Associates, Inc. | Devices and methods for occlusion of an atrial appendage |
US11173023B2 (en) | 2017-10-16 | 2021-11-16 | W. L. Gore & Associates, Inc. | Medical devices and anchors therefor |
CN108784772B (en) * | 2018-07-30 | 2024-04-16 | 中国人民解放军总医院第四医学中心 | Telescopic hemostatic air bag |
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FR2683449A1 (en) * | 1991-11-08 | 1993-05-14 | Cardon Alain | ENDOPROTHESIS FOR TRANSLUMINAL IMPLANTATION. |
US5449382A (en) * | 1992-11-04 | 1995-09-12 | Dayton; Michael P. | Minimally invasive bioactivated endoprosthesis for vessel repair |
US5817126A (en) * | 1997-03-17 | 1998-10-06 | Surface Genesis, Inc. | Compound stent |
WO1999034749A1 (en) * | 1998-01-08 | 1999-07-15 | Mark Wilson Ian Webster | Self-expanding bifurcation stent and delivery system |
-
2000
- 2000-09-25 EP EP00966878A patent/EP1233722A4/en not_active Withdrawn
- 2000-09-25 JP JP2001524539A patent/JP2003509158A/en active Pending
- 2000-09-25 KR KR1020027003827A patent/KR20020064882A/en not_active Application Discontinuation
- 2000-09-25 AU AU77159/00A patent/AU766043B2/en not_active Ceased
- 2000-09-25 NZ NZ517945A patent/NZ517945A/en not_active IP Right Cessation
- 2000-09-25 CA CA002383304A patent/CA2383304A1/en not_active Abandoned
- 2000-09-25 IL IL14865600A patent/IL148656A0/en unknown
- 2000-09-25 WO PCT/US2000/026378 patent/WO2001021109A1/en not_active Application Discontinuation
- 2000-09-25 CN CN00815878A patent/CN1391452A/en active Pending
-
2002
- 2002-11-27 HK HK02108558.5A patent/HK1046843A1/en unknown
Cited By (5)
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US9561126B2 (en) | 1996-11-04 | 2017-02-07 | Boston Scientific Scimed, Inc. | Catheter with attached flexible side sheath |
US9427340B2 (en) | 2004-12-14 | 2016-08-30 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
US9492297B2 (en) | 2006-09-12 | 2016-11-15 | Boston Scientific Scimed, Inc. | Multilayer balloon for bifurcated stent delivery and methods of making and using the same |
US8936567B2 (en) | 2007-11-14 | 2015-01-20 | Boston Scientific Scimed, Inc. | Balloon bifurcated lumen treatment |
US8932340B2 (en) | 2008-05-29 | 2015-01-13 | Boston Scientific Scimed, Inc. | Bifurcated stent and delivery system |
Also Published As
Publication number | Publication date |
---|---|
AU7715900A (en) | 2001-04-24 |
AU766043B2 (en) | 2003-10-09 |
KR20020064882A (en) | 2002-08-10 |
JP2003509158A (en) | 2003-03-11 |
CN1391452A (en) | 2003-01-15 |
HK1046843A1 (en) | 2003-01-30 |
WO2001021109A1 (en) | 2001-03-29 |
IL148656A0 (en) | 2002-09-12 |
EP1233722A4 (en) | 2003-06-11 |
NZ517945A (en) | 2003-09-26 |
EP1233722A1 (en) | 2002-08-28 |
CA2383304A1 (en) | 2001-03-29 |
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