WO2001012816A3 - Porcine endovirus gag and env and diagnostic uses thereof - Google Patents

Porcine endovirus gag and env and diagnostic uses thereof Download PDF

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Publication number
WO2001012816A3
WO2001012816A3 PCT/GB2000/003159 GB0003159W WO0112816A3 WO 2001012816 A3 WO2001012816 A3 WO 2001012816A3 GB 0003159 W GB0003159 W GB 0003159W WO 0112816 A3 WO0112816 A3 WO 0112816A3
Authority
WO
WIPO (PCT)
Prior art keywords
gag
poerv
env
porcine
endovirus
Prior art date
Application number
PCT/GB2000/003159
Other languages
French (fr)
Other versions
WO2001012816A2 (en
WO2001012816A9 (en
Inventor
Daniel Galbraith
Helena Kelly
Kenneth Smith
Original Assignee
Quip Technology Ltd
Daniel Galbraith
Helena Kelly
Kenneth Smith
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Quip Technology Ltd, Daniel Galbraith, Helena Kelly, Kenneth Smith filed Critical Quip Technology Ltd
Priority to EP00953333A priority Critical patent/EP1238087A2/en
Priority to AU65846/00A priority patent/AU6584600A/en
Publication of WO2001012816A2 publication Critical patent/WO2001012816A2/en
Publication of WO2001012816A3 publication Critical patent/WO2001012816A3/en
Publication of WO2001012816A9 publication Critical patent/WO2001012816A9/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/08—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses
    • C07K16/10—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from viruses from RNA viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/10022—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Abstract

The present invention relates to polypeptide fragments derived from porcine endogenous retrovirus (PoERV) GAG and ENV polypeptides, and to their use in detection of PoERV antibodies in a test sample. Also provided are antibodies to GAG and ENV polypeptides, which may be used to detect PoERV in a sample. Polypeptide sequences are provided which are common to several strains of PoERV, as are sequences specific to a single PoERV strain.
PCT/GB2000/003159 1999-08-18 2000-08-16 Porcine endovirus gag and env and diagnostic uses thereof WO2001012816A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP00953333A EP1238087A2 (en) 1999-08-18 2000-08-16 Porcine endovirus gag and env and diagnostic uses thereof
AU65846/00A AU6584600A (en) 1999-08-18 2000-08-16 Retrovirus assay

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9919604.0A GB9919604D0 (en) 1999-08-18 1999-08-18 Retrovirus assay
GB9919604.0 1999-08-18

Publications (3)

Publication Number Publication Date
WO2001012816A2 WO2001012816A2 (en) 2001-02-22
WO2001012816A3 true WO2001012816A3 (en) 2002-07-11
WO2001012816A9 WO2001012816A9 (en) 2002-12-12

Family

ID=10859410

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/003159 WO2001012816A2 (en) 1999-08-18 2000-08-16 Porcine endovirus gag and env and diagnostic uses thereof

Country Status (4)

Country Link
EP (1) EP1238087A2 (en)
AU (1) AU6584600A (en)
GB (1) GB9919604D0 (en)
WO (1) WO2001012816A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0313132D0 (en) * 2003-06-06 2003-07-09 Ich Productions Ltd Peptide ligands

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997040167A1 (en) * 1996-04-19 1997-10-30 Q-One Biotech Ltd. Porcine retrovirus

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997040167A1 (en) * 1996-04-19 1997-10-30 Q-One Biotech Ltd. Porcine retrovirus

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
AKIYOSHI D E ET AL: "IDENTIFICATION OF A FULL-LENGTH CDNA FOR AN ENDOGENOUS RETROVIRUS OF MINIATURE SWINE", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 72, no. 5, May 1998 (1998-05-01), pages 4503 - 4507, XP001002575, ISSN: 0022-538X *
BLUSCH J H ET AL: "A POLYMERASE CHAIN REACTION-BASED PROTOCOL FOR THE DETECTION OF TRANSMISSION OF PIG ENDOGENOUS RETROVIRUSES IN PIG TO HUMAN XENOTRANSPLANTATION", TRANSPLANTATION, WILLIAMS AND WILKINS, BALTIMORE, MD, US, vol. 69, no. 10, 27 May 2000 (2000-05-27), pages 2176 - 2172, XP001005967, ISSN: 0041-1337 *
GALBRAITH DN, KELLY HT, DYKE A, REID G, HAWORTH C, BEEKMAN J, SHEPHERD A, SMITH KT.: "Design and validation of immunological tests for the detection of Porcine endogenous retrovirus in biological materials.", J VIROL METHODS. 2000 NOV;90(2):115-24., XP001006236 *
MATTHEWS A L ET AL: "DEVELOPMENT AND VALIDATION OF A WESTERN IMMUNOBLOT ASSAY FOR DETECTION OF ANTIBODIES TO PORCINE ENDOGENOUS RETROVIRUS", TRANSPLANTATION, WILLIAMS AND WILKINS, BALTIMORE, MD, US, vol. 67, no. 7, 15 April 1999 (1999-04-15), pages 939 - 943, XP001006259, ISSN: 0041-1337 *
WILSON C A ET AL: "EXTENDED ANALYSIS OF THE IN VITRO TROPISM OF PORCINE ENDOGENOUS RETROVIRUS", JOURNAL OF VIROLOGY, THE AMERICAN SOCIETY FOR MICROBIOLOGY, US, vol. 74, no. 1, January 2000 (2000-01-01), pages 49 - 56, XP001002577, ISSN: 0022-538X *

Also Published As

Publication number Publication date
EP1238087A2 (en) 2002-09-11
WO2001012816A2 (en) 2001-02-22
WO2001012816A9 (en) 2002-12-12
GB9919604D0 (en) 1999-10-20
AU6584600A (en) 2001-03-13

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