WO2001012205A3 - Chemically-stabilized chlorite solutions for treating cancer - Google Patents

Chemically-stabilized chlorite solutions for treating cancer Download PDF

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Publication number
WO2001012205A3
WO2001012205A3 PCT/US2000/022610 US0022610W WO0112205A3 WO 2001012205 A3 WO2001012205 A3 WO 2001012205A3 US 0022610 W US0022610 W US 0022610W WO 0112205 A3 WO0112205 A3 WO 0112205A3
Authority
WO
WIPO (PCT)
Prior art keywords
stabilized chlorite
treating cancer
chlorite matrix
chemically
stabilized
Prior art date
Application number
PCT/US2000/022610
Other languages
French (fr)
Other versions
WO2001012205A2 (en
Inventor
Frederich W Kuhne
Vitam Kodelja
Original Assignee
Oxo Chemie Ag
Frederich W Kuhne
Vitam Kodelja
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Oxo Chemie Ag, Frederich W Kuhne, Vitam Kodelja filed Critical Oxo Chemie Ag
Priority to MXPA02001724A priority Critical patent/MXPA02001724A/en
Priority to NZ517673A priority patent/NZ517673A/en
Priority to AU69132/00A priority patent/AU6913200A/en
Priority to EP00957529A priority patent/EP1408994A2/en
Priority to KR1020027002066A priority patent/KR20020038728A/en
Priority to CA002382293A priority patent/CA2382293A1/en
Priority to IL14818900A priority patent/IL148189A0/en
Publication of WO2001012205A2 publication Critical patent/WO2001012205A2/en
Publication of WO2001012205A3 publication Critical patent/WO2001012205A3/en
Priority to NO20020751A priority patent/NO20020751L/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/20—Elemental chlorine; Inorganic compounds releasing chlorine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00—Medicinal preparations containing inorganic active ingredients
    • A61K33/40—Peroxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Abstract

Methods of using a stabilized chlorite matrix to modulate immune responses and treat cancer are disclosed. The stabilized chlorite matrix, when administered to a mammal in need thereof, can activate immune cells in a manner similar to interferon gamma but does not effect the production of inflammatory and shock related cytokines like tumor necrosis alpha. The stabilized chlorite matrix also upregulates the expression of the DCC protein in macrophages, a protein whose expression is related to neoplastic transformation. By activating macrophages, the stabilized chlorite matrix therefore is useful as an immunomodulatory agent and in treating cancer.
PCT/US2000/022610 1999-08-18 2000-08-18 Chemically-stabilized chlorite solutions for treating cancer WO2001012205A2 (en)

Priority Applications (8)

Application Number Priority Date Filing Date Title
MXPA02001724A MXPA02001724A (en) 1999-08-18 2000-08-18 Chemically-stabilized chlorite solutions for treating cancer and other diseases.
NZ517673A NZ517673A (en) 1999-08-18 2000-08-18 Chemically-stabilized chlorite solutions for treating cancer and other diseases
AU69132/00A AU6913200A (en) 1999-08-18 2000-08-18 Chemically-stabilized chlorite solutions for treating cancer and other diseases
EP00957529A EP1408994A2 (en) 1999-08-18 2000-08-18 Chemically-stabilized chlorite solutions for treating cancer
KR1020027002066A KR20020038728A (en) 1999-08-18 2000-08-18 Chemically-Stabilized Chlorite Solutions for Treating Cancer and Other Diseases
CA002382293A CA2382293A1 (en) 1999-08-18 2000-08-18 Chemically-stabilized chlorite solutions for treating cancer and other diseases
IL14818900A IL148189A0 (en) 1999-08-18 2000-08-18 Chemically-stabilized chlorite solutions for treating cancer and other diseases
NO20020751A NO20020751L (en) 1999-08-18 2002-02-15 Chemically stabilized chlorite solutions for the treatment of cancer and other diseases

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14942999P 1999-08-18 1999-08-18
US60/149,429 1999-08-18

Publications (2)

Publication Number Publication Date
WO2001012205A2 WO2001012205A2 (en) 2001-02-22
WO2001012205A3 true WO2001012205A3 (en) 2001-09-13

Family

ID=22530238

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/022610 WO2001012205A2 (en) 1999-08-18 2000-08-18 Chemically-stabilized chlorite solutions for treating cancer

Country Status (14)

Country Link
EP (1) EP1408994A2 (en)
KR (1) KR20020038728A (en)
CN (1) CN1378456A (en)
AU (1) AU6913200A (en)
CA (1) CA2382293A1 (en)
IL (1) IL148189A0 (en)
MX (1) MXPA02001724A (en)
NO (1) NO20020751L (en)
NZ (1) NZ517673A (en)
PL (1) PL353769A1 (en)
RU (1) RU2002106824A (en)
TR (1) TR200201182T2 (en)
WO (1) WO2001012205A2 (en)
ZA (1) ZA200201726B (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE451326T1 (en) 2003-11-21 2009-12-15 Cytotools Ag REACTIVE CHLORINE COMPOUNDS, THEIR DERIVATIVES, ANIONS AND SALTS AND METHOD FOR THEIR PRODUCTION AND USE
JP2009501734A (en) * 2005-07-21 2009-01-22 ヌボ・リサーチ・インコーポレイテッド How to treat cancer
IN2014DN05866A (en) 2011-12-22 2015-05-22 Nuvo Res Gmbh
CN112386606A (en) * 2019-08-19 2021-02-23 卢序 Use of an oxidizing agent having a second messenger effect to increase the active oxidation pressure

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200157A2 (en) * 1985-05-02 1986-11-05 OXO Chemie GmbH Use of an aqueous stabilized chlorite matrix solution for the manufacture of a medicament for the treatment of infectious conditions by intravenous administration
EP0200156A2 (en) * 1985-05-02 1986-11-05 OXO Chemie GmbH Use of an aqueous solution of a chlorite matrix for the manufacture of a medicament for treating tumours
WO1999017787A2 (en) * 1997-10-06 1999-04-15 Oxo Chemie Ag Use of a chemically-stabilized chlorite solution for inhibiting an antigen-specific immune response
WO2000048940A1 (en) * 1999-02-19 2000-08-24 Stahl Kurt Wilhelm Peroxochloric acid, derivatives and anions, salts thereof, method for producing them and use of the same

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0200157A2 (en) * 1985-05-02 1986-11-05 OXO Chemie GmbH Use of an aqueous stabilized chlorite matrix solution for the manufacture of a medicament for the treatment of infectious conditions by intravenous administration
EP0200156A2 (en) * 1985-05-02 1986-11-05 OXO Chemie GmbH Use of an aqueous solution of a chlorite matrix for the manufacture of a medicament for treating tumours
WO1999017787A2 (en) * 1997-10-06 1999-04-15 Oxo Chemie Ag Use of a chemically-stabilized chlorite solution for inhibiting an antigen-specific immune response
WO2000048940A1 (en) * 1999-02-19 2000-08-24 Stahl Kurt Wilhelm Peroxochloric acid, derivatives and anions, salts thereof, method for producing them and use of the same

Also Published As

Publication number Publication date
KR20020038728A (en) 2002-05-23
CN1378456A (en) 2002-11-06
EP1408994A2 (en) 2004-04-21
TR200201182T2 (en) 2002-08-21
ZA200201726B (en) 2003-12-31
CA2382293A1 (en) 2001-02-22
IL148189A0 (en) 2002-09-12
WO2001012205A2 (en) 2001-02-22
MXPA02001724A (en) 2004-09-06
NZ517673A (en) 2004-03-26
NO20020751D0 (en) 2002-02-15
AU6913200A (en) 2001-03-13
NO20020751L (en) 2002-04-17
PL353769A1 (en) 2003-12-01
RU2002106824A (en) 2003-11-27

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