WO2001009304A3 - Polynucleotides encoding aminolevulinic acid biosynthetic enzymes - Google Patents

Polynucleotides encoding aminolevulinic acid biosynthetic enzymes Download PDF

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Publication number
WO2001009304A3
WO2001009304A3 PCT/US2000/021008 US0021008W WO0109304A3 WO 2001009304 A3 WO2001009304 A3 WO 2001009304A3 US 0021008 W US0021008 W US 0021008W WO 0109304 A3 WO0109304 A3 WO 0109304A3
Authority
WO
WIPO (PCT)
Prior art keywords
aminolevulinic acid
acid biosynthetic
polynucleotides encoding
biosynthetic enzymes
biosynthetic enzyme
Prior art date
Application number
PCT/US2000/021008
Other languages
French (fr)
Other versions
WO2001009304A2 (en
Inventor
Rebecca E Cahoon
Steven Gutteridge
Leslie T Harvell
J Antoni Rafalski
Yong Tao
Zude Weng
Original Assignee
Du Pont
Rebecca E Cahoon
Steven Gutteridge
Leslie T Harvell
J Antoni Rafalski
Yong Tao
Zude Weng
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Du Pont, Rebecca E Cahoon, Steven Gutteridge, Leslie T Harvell, J Antoni Rafalski, Yong Tao, Zude Weng filed Critical Du Pont
Priority to EP00952382A priority Critical patent/EP1198573A2/en
Priority to US10/018,902 priority patent/US6916971B1/en
Priority to AU65091/00A priority patent/AU6509100A/en
Publication of WO2001009304A2 publication Critical patent/WO2001009304A2/en
Publication of WO2001009304A3 publication Critical patent/WO2001009304A3/en

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8261—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield
    • C12N15/8271—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance
    • C12N15/8274—Phenotypically and genetically modified plants via recombinant DNA technology with agronomic (input) traits, e.g. crop yield for stress resistance, e.g. heavy metal resistance for herbicide resistance
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/90—Isomerases (5.)

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Cell Biology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Nutrition Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)

Abstract

This invention relates to an isolated nucleic acid fragment encoding an aminolevulinic acid biosynthetic enzyme. The invention also relates to the construction of a chimeric gene encoding all or a portion of the aminolevulinic acid biosynthetic enzyme, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the aminolevulinic acid biosynthetic enzyme in a transformed host cell.
PCT/US2000/021008 1999-07-30 2000-07-28 Polynucleotides encoding aminolevulinic acid biosynthetic enzymes WO2001009304A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP00952382A EP1198573A2 (en) 1999-07-30 2000-07-28 Polynucleotides encoding aminolevulinic acid biosynthetic enzymes
US10/018,902 US6916971B1 (en) 1999-07-30 2000-07-28 Polynucleotides encoding aminolevulinic acid biosynthetic enzymes
AU65091/00A AU6509100A (en) 1999-07-30 2000-07-28 Polynucleotides encoding aminolevulinic acid biosynthetic enzymes

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14660099P 1999-07-30 1999-07-30
US60/146,600 1999-07-30

Publications (2)

Publication Number Publication Date
WO2001009304A2 WO2001009304A2 (en) 2001-02-08
WO2001009304A3 true WO2001009304A3 (en) 2001-11-15

Family

ID=22518131

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/021008 WO2001009304A2 (en) 1999-07-30 2000-07-28 Polynucleotides encoding aminolevulinic acid biosynthetic enzymes

Country Status (3)

Country Link
EP (1) EP1198573A2 (en)
AU (1) AU6509100A (en)
WO (1) WO2001009304A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2011007368A2 (en) 2009-07-14 2011-01-20 Cadila Healthcare Limited An improved process for preparation of olmesartan

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029880A2 (en) * 1997-12-10 1999-06-17 Aventis Cropscience Gmbh Method for producing transgenic plants with modified 5-aminolevulinic acid biosynthesis, method for identifying 5-aminolevulinic acid synthesis effectors

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999029880A2 (en) * 1997-12-10 1999-06-17 Aventis Cropscience Gmbh Method for producing transgenic plants with modified 5-aminolevulinic acid biosynthesis, method for identifying 5-aminolevulinic acid synthesis effectors

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 5 February 1999 (1999-02-05), NAKAYASHIKI ET AL.: "Nucleotide sequence of a cDNA clone encoding glutamyl-tRNA reductase from rice", XP002163686 *
GRIMM B: "PRIMARY STRUCTURE OF A KEY ENZYME IN PLANT TETRAPYRROLE SYNTHESIS GLUTAMATE 1-SEMIALDEHYDE AMINOTRANSFERASE", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 87, no. 11, 1990, 1990, pages 4169 - 4173, XP002163685, ISSN: 0027-8424 *
JAHN D ET AL: "GLUTAMYL-TRANSFER RNA A PRECURSOR OF HEME AND CHLOROPHYLL BIOSYNTHESIS", TRENDS IN BIOCHEMICAL SCIENCES, vol. 17, no. 6, 1992, pages 215 - 218, XP000990546, ISSN: 0376-5067 *
SANGWAN INDU ET AL: "Expression of a soybean gene encoding the tetrapyrrole-synthesis enzyme glutamyl-tRNA reductase in symbiotic root nodules.", PLANT PHYSIOLOGY (ROCKVILLE), vol. 119, no. 2, February 1999 (1999-02-01), pages 593 - 598, XP002163683, ISSN: 0032-0889 *
SANGWAN INDU ET AL: "Expression of the soybean (Glycine max) glutamate 1-semialdehyde aminotransferase gene in symbiotic root nodules.", PLANT PHYSIOLOGY (ROCKVILLE), vol. 102, no. 3, 1993, pages 829 - 834, XP002163684, ISSN: 0032-0889 *

Also Published As

Publication number Publication date
AU6509100A (en) 2001-02-19
WO2001009304A2 (en) 2001-02-08
EP1198573A2 (en) 2002-04-24

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