WO2001007163A1 - Appareil de prelevement d'echantillons pourvu d'une pipette fixee - Google Patents

Appareil de prelevement d'echantillons pourvu d'une pipette fixee Download PDF

Info

Publication number
WO2001007163A1
WO2001007163A1 PCT/US2000/040452 US0040452W WO0107163A1 WO 2001007163 A1 WO2001007163 A1 WO 2001007163A1 US 0040452 W US0040452 W US 0040452W WO 0107163 A1 WO0107163 A1 WO 0107163A1
Authority
WO
WIPO (PCT)
Prior art keywords
pipette
lid
cup
sample
sample collection
Prior art date
Application number
PCT/US2000/040452
Other languages
English (en)
Inventor
Richard J. Braun
Mitchell Owens
Bengt Erik Forsberg
Original Assignee
Medtox Scientific, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medtox Scientific, Inc. filed Critical Medtox Scientific, Inc.
Publication of WO2001007163A1 publication Critical patent/WO2001007163A1/fr

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
    • B01L3/508—Containers for the purpose of retaining a material to be analysed, e.g. test tubes rigid containers not provided for above
    • B01L3/5082—Test tubes per se
    • B01L3/50825—Closing or opening means, corks, bungs
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/0282—Burettes; Pipettes mounted within a receptacle
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D47/00—Closures with filling and discharging, or with discharging, devices
    • B65D47/04—Closures with discharging devices other than pumps
    • B65D47/06—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages
    • B65D47/065—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages with hinged, foldable or pivotable spouts
    • B65D47/066—Closures with discharging devices other than pumps with pouring spouts or tubes; with discharge nozzles or passages with hinged, foldable or pivotable spouts the spout being either flexible or having a flexible wall portion, whereby the spout is foldable between a dispensing and a non-dispensing position

Definitions

  • the present invention relates generally to sample testing systems, and specifically to sample container and transfer devices.
  • a sample usually urine, blood, or another bodily fluid
  • a portion of the first container is then poured into a second container.
  • a small amount of the sample is transferred to the testing apparatus by a pipette, a slender hollow tube used to transfer precise amounts of fluids.
  • the pipette is then disposed of.
  • the first container is opened again, another sample is poured from the first container into a third container, and a new pipette is used to transfer the sample to the testing apparatus.
  • Other methods of sample collection require pouring the sample from the first container into two secondary containers for storage and testing purposes.
  • Such systems can be improved upon.
  • the first container needs to be opened continuously to get samples from it. This increases the chance that the sample will be contaminated or spilled.
  • Pouring the sample from the first container to the second or third containers can also lead to spills and contamination.
  • having to use so many containers to perform just a few tests can also be a cause of contamination, spoiled samples, and generally unsanitary conditions.
  • when using pipettes most users simply lay them on a table when they are done with them, this is unsanitary.
  • using a new pipette for each sample transfer and then disposing of it is wasteful.
  • what is needed is a system to controllably contain and transfer samples for testing or storing without the risk of spilling or contamination.
  • the present invention provides a sample collection system which includes a sample collection apparatus including a sample holding cup and a lid for attaching to the cup.
  • the sample collection system also includes a pipette attached to the sample collection apparatus, the pipette having a closed position and an open position, a first end of the pipette is exposed on an outer surface of the sample collection apparatus and a second end of the pipette is exposed on an inner surface of the sample collection apparatus when the pipette is in the open position.
  • the present invention provides a system to contain a testing sample and transfer portions of the sample to a testing apparatus or another storage container without having to use an external pipette and without having to open the sample container.
  • sample handling outside of the collection container is eliminated for screening and testing processes and the present system provides an accurate method of sample delivery.
  • a pipette device can be molded into either the cup or lid or both. This provides for a fast, relatively simple, one piece manufacturing process.
  • Fig. 1 is a top view of a lid according to one embodiment of the present system.
  • Fig. 2 is a side view of the lid of Fig. 1
  • Fig. 3 is a top view of the lid of Fig. 1 with the pipette in an open position.
  • Fig. 4 is a side view of Fig. 3.
  • Fig. 5 is a view of a sample collection apparatus according to one embodiment the present invention.
  • Fig. 6 is a view of a sample collection apparatus according to another embodiment of the present invention.
  • Fig. 7 is a top view of a sample collection apparatus according to another embodiment of the present invention.
  • Fig. 8 is a side view of the sample collection apparatus of Fig. 7.
  • Fig. 9 is a side view of a lid for a sample collection apparatus according to another embodiment of the present invention.
  • Fig. 10 is a side view of a collection cup used with the lid of Fig. 9.
  • Fig. 11 is a side view of a sample collection apparatus according to another embodiment of the present invention.
  • Fig. 12 is a side view of a lid for a sample collection apparatus according to another embodiment of the present system.
  • Fig. 13 is a top view of Fig. 12.
  • Fig. 14 is a side view of a sample collection system according to another embodiment of the present invention.
  • FIGS 1-4 show a lid 100 for attaching to a collection cup in a sample collection system.
  • Lid 100 includes a cap member 101 and a pipette 103.
  • cap member 101 is a circular shaped cap molded from a plastic material. In other embodiments, other materials are used.
  • Cap member 101 has a threaded portion 204 along the interior side of an outer wall 205.
  • Cap member 101 also includes a wall 206 opposing wall 205. When lid 100 is attached to a collection cup, walls 205 and 206 form a seal with the rim of a collection cup so that a sample within the collection cup will not leak or spill.
  • cap member 101 also includes sealing members 102 and 201.
  • sealing members 102 and 201 are bumps or protrusions on lid 100.
  • Sealing member 102 is molded into a vertical wall 106 of cap member 101 and sealing member 201 is molded into a vertical wall 107 of cap member 101.
  • sealing members 102 and 201 are hemispherically shaped projections formed upon walls 106 and 107 respectively.
  • the sealing members can have a frustum conical shape or other shape that matches the shape of the open end of pipette 103.
  • Cap member 101 also includes a cavity 105 molded into a central portion of the surface of the cap.
  • the bottom of cavity 105 is defined by a horizontal surface 108 of cap 101.
  • the sides of cavity 105 are partially defined by the vertical walls 106 and 107.
  • Sealing members 102 and 201 are positioned on opposing sides of cavity 105 upon walls 106 and 107 respectively.
  • cavity 105 is sized or dimensioned so that a user can fit their finger within the cavity to move pipette 103 to an open position.
  • pipette 103 is a fluid or sample transfer conduit.
  • Exemplary pipette 103 has a thin central tube portion and an internal nozzle shape which permit the transfer of predictable and regulated amounts of liquid from a sample collection apparatus.
  • Pipette 103 includes an open end 202 and an opposing open end 203.
  • pipette 103 has a length that is substantially the same as the diameter of cavity 105 and the distance between sealing members 102 and 201, which are on opposing walls of cavity 105. This provides that when pipette 103 is in a closed or horizontal position within cavity 105 (see Fig. 2) open end 202 is sealed by sealing member 102 and/or open end 203 is sealed by sealing member 201.
  • the sealing members protrude so that they mate with the open ends of the pipette and provide a seal.
  • open end 202 is exposed to the outside on a first side 404 of lid 100 and open end 203 is exposed to a second side 405 of lid 100.
  • a sample within a collection cup that lid 100 is attached to can flow into pipette 103 through open end 203, flow through pipette 103, and flow out of the pipette through open end 202.
  • pipette 103 is molded from the same material and at the same time as cap member 101, thus giving lid 100 an integral, unitary construction. This provides for a fast and relatively simple manufacturing process of lid 100.
  • pipette 103 can be separately manufactured and attached to cap member 101.
  • pipette 103 has an internal diameter, length, and internal nozzle shape designed to deliver a predetermined, precise drop size to a testing or screening device.
  • pipette 103 can have a larger internal diameter which permits a higher flow rate, or a different internal nozzle shape which permits alternative flow rates. This would be used, for example, if the user wanted to transfer a portion of a sample, and not just a few drops, to another container.
  • pipette 103 has assorted sizes for allowing different flows as needed.
  • pipette 103 is connected to cap member 101 at the tip of a horizontal portion 403 of cap member 101. Horizontal portion 403 hangs over cavity 105 above the location of sealing member 201. Pipette 103 is attached to cap member 101 at a section above open end 203 of pipette 103 which is approximately the same distance as the length of horizontal portion 403. Thus, when pipette 103 is rotated to a closed position (see Fig. 2), open end 203 of pipette 103 mates with sealing member 201 and becomes sealed.
  • Pipette 103 is also connected to cap member 101 by a flexible hinging joint or section 104.
  • flexible hinging section 104 is molded from the same plastic material as cap member 101 and pipette 103. This provides for a fast, relatively simple, one piece manufacturing process.
  • flexible hinging section 104 can be separately manufactured and attached.
  • flexible hinging section 104 has a generally hemispherical shape when viewed from above lid 100.
  • One edge of flexible hinging section 104 is attached to cap member 101 within cavity 105.
  • the upper edge of flexible hinging section 104 is attached to pipette 103 at approximately the same height as the tip of horizontal portion 403 is attached to the pipette.
  • flexible hinging section 401 has a length which is longer than the direct distance between the point where it is attached to pipette 103 and the point where it is attached to cap member 101.
  • flexible hinging section 104 has a concave shape when the pipette is in a closed position (see Fig. 2), and a convex shape when the pipette is in an open position (see Fig. 4).
  • the convex and concave shapes of flexible hinging section 104 allow section 104 to act as a detent mechanism, providing force and tension to keep pipette in either the desired closed or open position.
  • Beneath flexible hinging section 104, cap member 101 has an opening to the collection cup. This permits a sample to leave the collection cup, go through the space beneath flexible hinging section 104, and enter pipette 103.
  • FIG. 5 shows a sample collection apparatus 500 according to one embodiment of the present invention.
  • Apparatus 500 includes a collection cup 501 having lid 100 attached thereto.
  • collection cup 501 is a molded plastic cylindrical shaped cup. Other embodiments include different shape, material, and sized cups as needed or desired.
  • Cup 501 is designed for the collection and storage of test samples such as urine, blood, body fluids, or other sampled fluids.
  • An upper end of cup 501 includes a threaded section (not shown) along an outer perimeter of the cup.
  • lid 100 includes cap member 101 and pipette 103 as described above. Threaded portion 204 of cap member 101 allows lid 100 to be removably attached to cup 501.
  • FIG. 5 shows how apparatus 500 may be used to extract a sample onto a testing apparatus 502.
  • pipette 103 can then be closed and reopened as many times as needed to transfer or test more partial samples from the original sample.
  • Figure 6 shows a sample collection apparatus 600 according to one embodiment of the present invention.
  • Apparatus 600 includes a collection cup 601, a lid 608, and a pipette 604.
  • collection cup 601 is a molded plastic cylindrical shaped cup.
  • Cup 601 is designed for the collection and storage of test samples such as urine, blood, body fluids, or other sampled fluids.
  • An upper end of cup 601 includes a threaded section along an outer perimeter of the cup (not shown).
  • Lid 608 also has a threaded section matching cup 601 threaded section. This allows lid 608 to be removably attached to cup 601.
  • Cup 601 includes a cavity 609 molded into a surface of the cup.
  • the bottom of cavity 609 is defined by a vertical surface of cup 601.
  • the sides of cavity 609 are partially defined by horizontal walls 610 and 611.
  • cavity 609 is sized or dimensioned so that a user can fit their finger within the cavity to open pipette 604.
  • cup 601 includes sealing members 602 and 603 which are positioned on opposing sides of cavity 609 upon walls 610 and 611 respectively.
  • Sealing member 602 is molded into horizontal wall 610 and sealing member 603 is molded into horizontal wall 611.
  • sealing members 602 and 603 are hemispherically shaped projections formed upon walls 610 and 611 respectively.
  • the sealing members can have a frustum conical shape or any shape that matches the shape of the open end of a pipette 604.
  • Pipette 604 includes a thin central tube portion which permits the transfer of predictable and regulated amounts of liquid from cup 601.
  • Pipette 604 includes an open end 606 and an opposing open end 607.
  • Pipette 604 has a length that is substantially the same as the diameter of cavity 609 and the distance between sealing members 602 and 603, which are on opposing walls of cavity 609. This is so that when pipette 604 is in a closed, or vertical, position within cavity 609, open end 606 is sealed by sealing member 602 and open end 607 is sealed by sealing member 603.
  • open end 606 is exposed to the outside and open end 607 is exposed to a sample within cup 601.
  • pipette 604 has an internal diameter, length, and internal nozzle shape designed to deliver a predetermined, precise drop size to a testing or screening device.
  • pipette 604 can have a larger internal diameter which permits a higher flow rate, or a different internal nozzle shape which permits alternative flow rates.
  • pipette 604 is molded from the same material and at the same time as cup 601. This provides for a fast and relatively simple one piece manufacturing process.
  • pipette 604 can be separately manufactured and attached to cup 601.
  • Pipette 604 is connected to cup 601 at the tip of a vertical portion 612 of cup 601. Vertical portion 612 hangs over cavity 609 at the location of sealing member 603.
  • Pipette 604 is attached to cup 601 at a section from open end 607 of pipette 604 which is the same distance as vertical portion 612.
  • Pipette 604 is also connected to cup 601 by a flexible hinging section 605.
  • flexible hinging section 605 is molded from the same plastic material as cup 601 and pipette 604. This provides for a fast and relatively simple one piece manufacturing process.
  • flexible hinging section 605 can be separately attached.
  • One edge of flexible hinging section 605 is attached to cup 601 within cavity 609 forming a generally hemispherical pattern.
  • the upper edge of flexible hinging section 605 is attached to pipette 604 at approximately the same height as the pipette is connected to vertical portion 612.
  • flexible hinging section 605 has a length which is longer than the direct distance between the point where it is attached to pipette 604 and the point where it is attached to cup 601. This permits flexible hinging section 605 to have a concave shape when the pipette is in a closed position, and a convex shape when the pipette is in an open position (see Fig. 6).
  • the convex and concave shapes of flexible hinging section 605 act as a detent mechanism, providing force and tension to keep pipette in either the desired closed or open position. Beneath flexible hinging section 605 there is an opening to the collection cup.
  • pipette 604 is attached to cup 601 so that when it is open it has a generally upward pointing angle. This provides a user with better control of the flow of a sample.
  • FIGS 7 and 8 show a top view and a side view of a sample collection system 700 according to one embodiment of the present invention.
  • Sample collection system 700 includes a collection cup 701 and a lid 702.
  • Lid 702 includes a cap member 708, a pipette 706, sealing members 805 and 808, and a cavity 705 which are substantially equivalent to the features in Figures 1-4 described above.
  • Lid 702 also includes a lip or flange 805 molded around the inner circumference of lid 702. The presence of flange 805 creates a cavity 809 in the lid.
  • Exemplary collection cup 701 includes a collar or flange 703 at an upper portion of the rim of the collection cup.
  • flange 703 can be forced passed lid flange 805 and into cavity 809. This provides a tightly sealed lid on collection cup 701.
  • Sample collection system 700 also includes a hinged member 704 for hingedly attaching lid 702 to collection cup 701.
  • hinged member 704 is molded from the same plastic material and at the same time as cup 701 and lid 702. This provides for a fast and relatively simple one piece manufacturing process. Alternatively, hinged member 704 can be separately attached.
  • Hinged member 704 contains a hinging portion 806 approximately halfway between lid 702 and collection cup 703. This permits lid 702 to be rotated and placed upon collection cup 701.
  • Lid 702 also includes a projection 707.
  • Projection 707 is attached at an outer portion of lid 702 substantially opposite the hinged member 704. This permits a user to press against projection 707 when the lid is on the collection cup and create enough force to release cavity 809 from around flange 703, thus opening the collection cup for use or transfer.
  • projection 707 and hinged member 704 also permit sample collection system 700 to be used in a machine that automates the opening and transfer of the sample in the collection cup.
  • collection system 700 permits collection system 700 to be used for both automatic sample transfer using a machine or manual transfer via the pipette.
  • collection cup 701 and lid 702 have a substantially circular shape when viewed from above.
  • each can have an oval shape. Having an oval shape provides a more convenient size and shape for a woman who must use the system for providing a urine sample.
  • lid 702 has a substantially circular shape when viewed from above.
  • each can have an oval shape. Having an oval shape provides a more convenient size and shape for a woman who must use the system for providing a urine sample.
  • 702 can be used as a handle for holding the collection cup in the correct position.
  • oval shaped collection apparatus Another feature of an oval shaped collection apparatus is that if a sample in the cup needs to be poured into another container, the narrow ends of the oval shape provide a pouring channel to help reduce any possible spills.
  • other shapes for the system include having a rectangular shape.
  • collection cup 701 includes a projection molded to the cup so that lid projection 707 opposes the cup projection when the lid is placed upon the cup.
  • either projection can also include a tamper proofing device, such as a one-way closure tab or other mechanism which breaks upon the opening of the lid, to permit the lid to be sealed in a tamper proof manner.
  • FIGS 9 and 10 show a collection cup 1000 and a lid 900 according to another embodiment of the present invention.
  • Lid 900 includes a cap member 901, a pipette 902, sealing members, and a cavity which are substantially equivalent to the features in Figures 1-4 described above.
  • Lid 900 also includes a lip or flange 906 molded around the inner circumference of lid 900. The presence of flange 906 creates a cavity 905 in the lid.
  • Collection cup 1000 includes a collar or flange 1002 at an upper portion of the rim of the collection cup.
  • flange 1002 can be forced passed lid flange 906 and into cavity 905. This provides a tight sealed lid on collection cup 1000.
  • Lid 900 also includes a projection 903.
  • Projection 903 is attached at an outer portion of lid 900. This permits a user to press against projection 903 when the lid is on the collection cup and create enough force to release cavity
  • collection cup 1000 includes a projection molded to the cup so that lid projection 903 opposes the cup projection when the lid is placed upon the cup.
  • either projection can include a tamper proofing device, such as a one-way closure tab or other mechamsm which breaks upon the opening of the lid. Such a device permits the lid to be sealed in a tamper proof manner upon collection cup 1000.
  • FIG 11 shows a sample collection system 1100 according to one embodiment of the present invention.
  • Sample collection system 1100 includes a collection cup 1101 and a lid 1102.
  • Cup 1101 includes a pipette 1108, sealing members, a cavity, and a flexible hinging section 1109 which are substantially equivalent to the features in Figures 6, described above.
  • Lid 1102 includes a lip or flange 1105 molded around the inner circumference of lid 1102 and a ridge 1104 molded a small distance from the outer wall. The presence of flange 1105 and ridge 1104 create a cavity 1106 in the lid.
  • Collection cup 1101 also includes a collar or flange 1103 at an upper portion of the rim of the collection cup. When lid 1102 is placed on collection cup 1101, flange 1103 can be forced passed lid flange 1105 and into cavity 1106. This provides a tight sealed lid on collection cup 1101.
  • Sample collection system 1100 also includes a hinged member 1110 for hingedly attaching lid 1102 to collection cup 1101. In one embodiment, hinged member 1110 is molded from the same plastic material as cup 1101 and lid 1102.
  • hinged member 1110 can be separately attached.
  • Hinged member 1110 contains a hinging portion 1111 approximately halfway between lid 1102 and collection cup 1101. This permits lid 1102 to be rotated and placed upon collection cup 1101.
  • Lid 1102 also includes a projection 1107.
  • Projection 1107 is attached at an outer portion of lid 1102 approximately opposite the hinged member 1110. This permits a user to press against projection 1107 when the lid is on the collection cup and create enough force to release cavity 1106 from around flange 1103, thus opening the collection cup for sample collection or transfer.
  • projection 1107 and hinged member 1110 also permit sample collection system 1100 to be used in a machine that automates the opening and transfer of the sample in the collection cup as described above.
  • collection cup 1101 and lid 1102 have a substantially circular shape when viewed from above.
  • each can have an oval shape, as described above concerning cup 701 and lid 702.
  • Figures 12 and 13 show a top and side view of a collection system lid
  • Lid 1200 includes substantially the same features as lid 100 shown in Figures 1-4 and described above. However, lid 1200 includes two pipettes, a first pipette 1210 and a second pipette 1310.
  • Pipette 1210 includes a thin central tube portion and narrow nozzle which permit the transfer of predictable and regulated amounts of liquid from a sample collection apparatus. It is sealed by sealing members 1304 and 1308.
  • Pipette 1210 is connected to cap member 1201 by a flexible hinging section 1220. In the exemplary embodiment, pipette 1310 is located parallel to pipette
  • Each pipette is independently attached to lid 1200 so that each can be opened and closed independent of the other.
  • pipette 1310 has a relatively larger internal diameter than pipette 1210, thus permitting a higher flow rate.
  • Pipette 1310 would be used, for example, if the user wanted to transfer a portion of a sample, and not just a few drops, to another container.
  • pipette 1310 can be designed having a different internal nozzle shape than pipette 1210.
  • Pipette 1310 is sealed by sealing members 1302 and/or 1306 and is connected to cap member
  • each pipette remains sealed while the other is being used.
  • FIG 14 shows a cross section side view of a collection system 1400 according to one embodiment of the present invention.
  • System 1400 includes substantially the same features as sample collection system 700 shown in Figures 7 and 8 and described above.
  • System 1400 includes a collection cup 1401 and a lid 1402 hingedly attached to cup 1401.
  • the system also includes two pipettes, a first pipette 1403 and a second pipette 1404. In one embodiment, these pipettes can have different internal diameters or different nozzle sizes, thus providing the advantages described above regarding lid 1200.
  • lid 100 is screwed securely onto the cup.
  • Lid 100 has cap 101 and pipette 103 molded into it so that pipette 103 can be pulled up from a normally closed position with a thumb and forefinger.
  • pipette 103 is sealed at one or both ends. This is accomplished by one or more molded sealing members 102 and 201 incorporated into the cap.
  • pipette 103 Once pipette 103 has been pulled up and into an open position, pipette 103 is open at both ends, with one end 203 inside the cap and open to the sample, and the other end 202 open to the outside. Collection cup 501 can then be inverted to begin dispensing the desired sample volume to a screening device, testing mechanism, or other collection container.
  • the internal diameter, length, and internal nozzle design of pipette 103 are designed to deliver a precise drop size, which is necessary in many screening and testing formats. In one embodiment, this is accomplished by squeezing the side of collection cup 501 while in an inverted position.
  • the internal diameter, length, and internal nozzle shape of a pipette can be modified to provide a higher sample flow rate from the inverted position if a larger volume is required, such as transferring a portion of the original sample into another container for sample retention or further testing.
  • more than one pipette can be incorporated into the cup, thus permitting one pipette for drop-by-drop sample testing transfer, and a larger pipette for quickly transferring a larger portion of the sample into a different container.
  • the present invention relates to any collection and transfer of a sample which requires an intervention with an external transfer device such as a transfer pipette, swab, capillary tube and so on, to perform a screen, test, split collection, split storage, split transfer and the like.
  • an external transfer device such as a transfer pipette, swab, capillary tube and so on, to perform a screen, test, split collection, split storage, split transfer and the like.
  • sample handling outside of the collection container is eliminated for screening and testing processes and utilizing the present system provides an accurate method of sample delivery.
  • the pipette device can be molded into the cup or into the lid to form a unitary structure. This provides for a fast, relatively simple, one piece manufacturing process.

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Analytical Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Hematology (AREA)
  • Sampling And Sample Adjustment (AREA)

Abstract

L'invention concerne un système de prélèvement d'échantillons (600) comportant un récipient d'échantillons (601) et un couvercle (608) destiné à être fixé sur ce récipient (601). Ce système de prélèvement d'échantillons comporte également une pipette (604) fixée sur l'appareil de prélèvement d'échantillons (600), laquelle pipette (604) comprend une position fermée et une position ouverte. Une première extrémité (606) de la pipette est à découvert sur une surface extérieure de l'appareil de prélèvement d'échantillons (600) et une seconde extrémité (607) de la pipette (604) est à découvert sur une surface extérieure de l'appareil de prélèvement d'échantillons (600) lorsque la pipette (604) se trouve en position ouverte.
PCT/US2000/040452 1999-07-22 2000-07-21 Appareil de prelevement d'echantillons pourvu d'une pipette fixee WO2001007163A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US14504799P 1999-07-22 1999-07-22
US60/145,047 1999-07-22
US17181899P 1999-12-21 1999-12-21
US60/171,818 1999-12-21

Publications (1)

Publication Number Publication Date
WO2001007163A1 true WO2001007163A1 (fr) 2001-02-01

Family

ID=26842607

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/040452 WO2001007163A1 (fr) 1999-07-22 2000-07-21 Appareil de prelevement d'echantillons pourvu d'une pipette fixee

Country Status (1)

Country Link
WO (1) WO2001007163A1 (fr)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108482836A (zh) * 2018-03-22 2018-09-04 黑龙江鸿葵科技有限公司 一种防止内装液体被调换的容器
CN109696556A (zh) * 2017-10-24 2019-04-30 豪夫迈·罗氏有限公司 移液装置和移液装置定位系统

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4982854A (en) * 1989-07-18 1991-01-08 Kabushikikaisha Matumotoya Shokuhin Beverage container with sipping tube
US5139174A (en) * 1987-01-02 1992-08-18 Helena Laboratories Corporation Method and apparatus for dispensing liquids
US5163583A (en) * 1992-01-03 1992-11-17 Whitworth Ted N Aspiration cap for dispensing blood or other fluids for diagnostic purposes
US5273172A (en) * 1991-11-11 1993-12-28 Marsteller & Killmann Gmbh & Co. Kg Closure device for drinking from containers
US5477994A (en) * 1994-06-20 1995-12-26 Rubbermaid Incorporated Beverage container valve
EP0698564A1 (fr) * 1993-01-29 1996-02-28 Willem Johannes Smith Récipient pour boissons avec une paille intégrale
EP0908237A2 (fr) * 1997-09-12 1999-04-14 Becton, Dickinson and Company Fermeture à rotule avec bec verseur pour récipient de collection d'échantillons

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5139174A (en) * 1987-01-02 1992-08-18 Helena Laboratories Corporation Method and apparatus for dispensing liquids
US4982854A (en) * 1989-07-18 1991-01-08 Kabushikikaisha Matumotoya Shokuhin Beverage container with sipping tube
US5273172A (en) * 1991-11-11 1993-12-28 Marsteller & Killmann Gmbh & Co. Kg Closure device for drinking from containers
US5163583A (en) * 1992-01-03 1992-11-17 Whitworth Ted N Aspiration cap for dispensing blood or other fluids for diagnostic purposes
EP0698564A1 (fr) * 1993-01-29 1996-02-28 Willem Johannes Smith Récipient pour boissons avec une paille intégrale
US5477994A (en) * 1994-06-20 1995-12-26 Rubbermaid Incorporated Beverage container valve
EP0908237A2 (fr) * 1997-09-12 1999-04-14 Becton, Dickinson and Company Fermeture à rotule avec bec verseur pour récipient de collection d'échantillons

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109696556A (zh) * 2017-10-24 2019-04-30 豪夫迈·罗氏有限公司 移液装置和移液装置定位系统
CN109696556B (zh) * 2017-10-24 2023-08-22 豪夫迈·罗氏有限公司 移液装置和移液装置定位系统
CN108482836A (zh) * 2018-03-22 2018-09-04 黑龙江鸿葵科技有限公司 一种防止内装液体被调换的容器
CN108482836B (zh) * 2018-03-22 2019-01-18 黑龙江鸿葵科技有限公司 一种防止内装液体被调换的容器

Similar Documents

Publication Publication Date Title
US6054099A (en) Urine specimen container
US4109530A (en) Specimen transfer container
US6361744B1 (en) Self-resealing closure for containers
US6752965B2 (en) Self resealing elastomeric closure
US3832738A (en) Mid-stream urine collector
US6171261B1 (en) Specimen collection device and method of delivering fluid specimens to test tubes
US4811866A (en) Method and apparatus for dispensing liquids
EP0908236B9 (fr) Fermeture à rotule avec un joint d'étanchéité en élastomère pour récipient de collection d'échantillons
US6680027B2 (en) Fluid sample collection and isolation cup
EP0820812B1 (fr) Dispositif de prélèvement d'échantillons
US20110130740A1 (en) Medication Bottle for Use with Oral Syringe
EP1284160A2 (fr) Dispositif pour le prélèvement d'échantillons liquides
US6136275A (en) Ball and socket closure for specimen collection container
US4895167A (en) Urine collecting and holding device for delivery to analytical laboratories
US20030053938A1 (en) Liquid specimen collection container
AU8320098A (en) Ball and socket closure for specimen collection container incorporating an integral flexible seal
AU8317698A (en) Ball and socket closure for specimen collection container incorporating a septum
US4925065A (en) Dispensing apparatus
US5259956A (en) Tube liquid dispenser
NZ234735A (en) Sputum collection system; wedged cap removable from sheild through side opening in shield wall
US6293435B1 (en) Liquid sample collection and transport system
US4326959A (en) Blood separator and dispenser
US3983037A (en) Apparatus for transfer, storage, and distribution of liquid
US20020057996A1 (en) Centrifuge tube assembly
WO2001007163A1 (fr) Appareil de prelevement d'echantillons pourvu d'une pipette fixee

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): CA US

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE

121 Ep: the epo has been informed by wipo that ep was designated in this application
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
122 Ep: pct application non-entry in european phase