WO2001005336A1 - Implant destine a remplir des defauts de cartilage et d'os dans les articulations - Google Patents

Implant destine a remplir des defauts de cartilage et d'os dans les articulations Download PDF

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Publication number
WO2001005336A1
WO2001005336A1 PCT/EP2000/005556 EP0005556W WO0105336A1 WO 2001005336 A1 WO2001005336 A1 WO 2001005336A1 EP 0005556 W EP0005556 W EP 0005556W WO 0105336 A1 WO0105336 A1 WO 0105336A1
Authority
WO
WIPO (PCT)
Prior art keywords
implant
cartilage
sliding
sliding head
bone
Prior art date
Application number
PCT/EP2000/005556
Other languages
German (de)
English (en)
Inventor
Hans Grundei
Wolfram Thomas
Original Assignee
Eska Implants Gmbh & Co.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19933382A external-priority patent/DE19933382A1/de
Application filed by Eska Implants Gmbh & Co. filed Critical Eska Implants Gmbh & Co.
Publication of WO2001005336A1 publication Critical patent/WO2001005336A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30756—Cartilage endoprostheses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00—Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/02—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/38—Joints for elbows or knees
    • A61F2/3859—Femoral components
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30108—Shapes
    • A61F2002/30199—Three-dimensional shapes
    • A61F2002/30299—Three-dimensional shapes umbrella-shaped or mushroom-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2002/30001—Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30316—The prosthesis having different structural features at different locations within the same prosthesis; Connections between prosthetic parts; Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30535—Special structural features of bone or joint prostheses not otherwise provided for
    • A61F2002/30604—Special structural features of bone or joint prostheses not otherwise provided for modular
    • A61F2002/30616—Sets comprising a plurality of prosthetic parts of different sizes or orientations
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/30767—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth
    • A61F2/30771—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves
    • A61F2002/30878—Special external or bone-contacting surface, e.g. coating for improving bone ingrowth applied in original prostheses, e.g. holes or grooves with non-sharp protrusions, for instance contacting the bone for anchoring, e.g. keels, pegs, pins, posts, shanks, stems, struts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/30—Joints
    • A61F2/3094—Designing or manufacturing processes
    • A61F2002/30971—Laminates, i.e. layered products
    • A61F2002/30973—Two joined adjacent layers having complementary interlocking protrusions and recesses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2230/00—Geometry of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2230/0063—Three-dimensional shapes
    • A61F2230/0093—Umbrella-shaped, e.g. mushroom-shaped
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00011—Metals or alloys
    • A61F2310/00023—Titanium or titanium-based alloys, e.g. Ti-Ni alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00185—Ceramics or ceramic-like structures based on metal oxides
    • A61F2310/00203—Ceramics or ceramic-like structures based on metal oxides containing alumina or aluminium oxide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00—Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005—The prosthesis being constructed from a particular material
    • A61F2310/00179—Ceramics or ceramic-like structures
    • A61F2310/00185—Ceramics or ceramic-like structures based on metal oxides
    • A61F2310/00239—Ceramics or ceramic-like structures based on metal oxides containing zirconia or zirconium oxide ZrO2

Definitions

  • the present invention is concerned with an implant for filling cartilage and bone defects in joints, such as in the knee joint.
  • Cartilage and bone damage in joints can generally be countered by implanting a total replacement implant. Due to the massive nature of such an intervention, efforts are made to leave as much natural material in the joint as possible. Of course, this does not apply to all indications. In the case of a tumor, for example, it is often not possible to avoid implanting a total endoprosthesis. However, there are often defects that are more amenable to gentler treatment. For example, arthroscopic surgery can be used to treat cartilage and bone defects on an outpatient basis by transplanting the patient's cartilage from a less stressed joint area into the cartilage defect area.
  • Such cartilage defects are the result of, for example, osteoarthritis, which is accompanied by excessive and premature abrasion of the cartilage, as a result of which the coating that covers the bone ends becomes ever thinner and ultimately results in bone defects.
  • Another surgical technique that deals with this topic is, for example, cartilage cell transplantation, in which, after genetic engineering of the body's own cartilage cells, attempts are made to rebuild the cartilage by injecting these cultured cells in the area of the cartilage and bone defects. Aim of all of these efforts is to restore the natural function of the joint using the body's own material or the material obtained from it.
  • cartilage material is removed from a healthy joint area in order to be inserted into the area of the cartilage and bone defects and to heal there.
  • a weakening of the cartilage material which is in itself healthy, is consciously accepted in order to remedy the cartilage defect.
  • the object of the present invention is to remedy this, ie to provide an implant for filling cartilage and bone defects, in which no additional weakening of the patient's healthy cartilage material is carried out.
  • the implant should be accessible to arthroscopic surgery.
  • the implant according to the invention has a reinforcing body with at least one anchoring pin to be driven into the bone and a head plate connected to it. This is embedded in a sliding head made of a biocompatible, abrasion-resistant material, the surface of which faces away from the anchoring pin is designed as a sliding surface.
  • the implant according to the invention thus takes the place of cartilage material that was previously removed from a healthy area in previous arthroscopic surgery and for filling up the cartilage and Bone defect served.
  • the implant has a nail-like structure.
  • the implant, with its anchoring pin, which particularly preferably has a conically tapering end, is hammered into the bone at the bottom of the cartilage and bone defect by means of several strikes by means of a percussion instrument on the head or sliding head.
  • the top plate of the optionally metallic reinforcement body sits on the at least one anchoring pin. This is embedded or cast into a biocompatible, abrasion-resistant material, which forms the sliding partner for the natural sliding surfaces of the other joint part.
  • cartilaginous connective tissue is granulated into any space between the sliding head and the natural cartilage. This also applies when using several implants according to the invention to fill a larger cartilage and bone defect. The gaps between several implants granulate with cartilaginous connective tissue after a certain time. The surface or sliding surface of the cartilage and bone defect filled with one or more implants then performs the function of natural cartilage.
  • the distances between the anchoring pins must be determined so that the sliding heads in the peripheral area touch, but do not overlap, since they would otherwise form a stepped surface that could not function as a sliding surface.
  • This is achieved by using placement devices that have the same dimensions as the implants that are then used in the procedure.
  • the surgeon first places a placer with his pin, which represents the anchoring pin of the implant, on the bottom of the cartilage and bone defect to be filled and marks the point at which the anchoring pin is later driven into the bone by gently hitting the head plate. Then a second placer is placed so that its head plate that of the first placer just touches and the point at which the anchoring pin of the second implant is to be driven is also marked by a light blow on the head plate.
  • the surgeon carries out these steps until he has filled the cartilage and bone defect practically completely with the placers by using a sufficient number and possibly using different sizes of the implant. He then removes the placers and then drives the corresponding implants with their anchoring pins into the respective marked locations in the bones.
  • a particularly strong hold of the sliding head on the reinforcement body can be achieved if the head plate is provided with openings through which material of the sliding head extends.
  • a particularly intimate connection between the head plate and sliding head is achieved when the sliding head is cast with the head plate.
  • the biocompatible material of the sliding head can be polyurethane, for example.
  • the selection of the biocompatible material of the sliding head as bioceramic is particularly preferred. This can advantageously be a glass ceramic, an aluminum oxide ceramic or a zirconium oxide ceramic.
  • a composite material can also be used with advantage, as is described, for example, in EP-B-0502082 in connection with a composite pan.
  • the implant according to the invention have a base body with at least one anchoring pin to be driven into the bone and a sliding head connected to it.
  • At least the sliding head consists of a biocompatible, abrasion-resistant material whose surface facing away from the anchoring pin is designed as a sliding surface.
  • the base body and the sliding head can consist of the same material. It is particularly preferred in this embodiment that the base body and sliding head are formed in one piece.
  • the material for the biocompatible material is again polyurethane, bioceramics (glass ceramics, aluminum oxide ceramics, zirconium oxide ceramics) and the composite material mentioned above.
  • a completely metallic implant made of titanium, for example, is also conceivable.
  • the height of the sliding head is in the range between 2 and 6 mm. If several implants are used, depending on the shape of the cartilage and bone defect, implants with different heights can be used. The aim is to produce a surface that is as smooth as possible and clings to the sliding surface of the cartilage and cartilage defect that follows. In addition, the height of the sliding head can lead to a stability of the hinges.
  • the sliding head is circular with a diameter range of 6 to 16 mm.
  • implants with different diameters can be used in order to fill the existing defect as optimally and completely as possible.
  • FIG. 1 shows the schematic view of the implant according to the invention in accordance with the first proposal
  • Figure 2 shows the view of the top plate of the reinforcement body
  • Figure 3 shows the schematic view of the implant according to the second proposed solution
  • Figure 4 schematically the filling of a cartilage
  • Figure 5 is a schematic side view of the condyle of a knee joint with filled cartilage and bone defect.
  • the implant 1 is shown schematically in FIG. It has a reinforcing body 2, which in the present case is equipped with only one anchoring pin 3.
  • the head plate 4 is attached to the anchoring pin 3.
  • the reinforcing body 2 is preferably made of metal, for example titanium.
  • the head plate 4 is embedded in a sliding head 5, the material of which has the said properties with regard to biocompatibility and abrasion resistance.
  • the surface of the sliding head 5 facing away from the anchoring pin 3 is designed as a sliding surface 6, as indicated by the rounding in FIG. 1 in the present case.
  • the sliding surface 6 works together with the natural cartilage of the other joint part.
  • the sliding head 5 has a height H and a diameter D. With different diameters D and different structural heights H, different implants can be represented which are suitable for forming a sliding surface which is essentially continuous towards the outside, following the natural cartilage which is still present, as will be explained below with reference to FIG. 5.
  • FIG 2 shows the view of the armoring body 2 of the implant according to Figure 1 from below.
  • the anchoring pin 3 is attached to the head plate 4 and is surrounded by openings 7.
  • the openings 7 ensure an intimate bond between the reinforcing body 2 and the material of the sliding head 5.
  • the sliding head 5 can have appropriately designed lugs (not shown) which can lock in the openings 7, so produce a form closure.
  • Figure 3 shows schematically the side view of the implant 1 '.
  • the sliding head 5 ' is formed in one piece with the anchoring pin 3' of the base body 2 '.
  • the surface of the sliding head 5 'facing away from the anchoring pin 3' is designed as a sliding surface 6 '.
  • the implant 1 ' can consist of ceramic or metal. With regard to the structural height H and the diameter D of the sliding head 5 ', the same applies as explained above for the first embodiment.
  • FIG. 4 now shows schematically how a cartilage and bone defect 10 can be filled in a condyle 9 on the femur 8.
  • Remaining gaps 12 between the individual implants 1 are granulated over time by cartilaginous connective tissue.
  • FIG. 5 schematically indicates how a cartilage and bone defect 10 is filled in the natural cartilage layer 11 on the condyles of a knee joint.
  • Several individual implants 1 are arranged and hammered into the bone in such a way that the smoothest possible sliding surface adjoins the natural cartilage layer 11.
  • the implant With the implant it is possible to treat the relatively easy to fix cartilage and bone defects in a targeted manner without the need for serious interventions. Rather, the implant can be implanted using arthroscopic surgery. The patient is spared the need to undergo total resection of the joint when simple cartilage defects occur. Over a period of several years, an overall implant produced with the implant according to the invention can ensure that the patient can move his joint without symptoms for several years.
  • the different structural heights of the implants also serve to lead to stability of the side bands after the defect has been filled.
  • the side band in question slackens in the area of a defect. After the cartilage and bone defect has been filled with the implant, it regains its natural tension, which is conducive to the overall stability of the joint.

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  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Medicinal Chemistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Cardiology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)

Abstract

L'invention concerne un implant (1) destiné à remplir des défauts de cartilage et d'os (10) dans les articulations. Cet implant possède un corps armature (2) comprenant au moins une cheville d'ancrage (3) à enfoncer dans l'os et une plaque frontale (4) reliée à cette cheville. La plaque frontale (4) est incorporée dans une tête glissante (5) réalisée dans un matériau biocompatible et résistante à l'abrasion. La surface de la tête glissante (5) opposée à la cheville d'ancrage (3) est conçue comme une surface glissante (6). En variante, l'implant présente un corps de base comprenant au moins une cheville d'ancrage à enfoncer dans l'os et une tête glissante également réalisée dans un matériau biocompatible et résistante à l'abrasion.
PCT/EP2000/005556 1999-07-16 2000-06-16 Implant destine a remplir des defauts de cartilage et d'os dans les articulations WO2001005336A1 (fr)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19932710.6 1999-07-16
DE19932710 1999-07-16
DE19933382.3 1999-07-21
DE19933382A DE19933382A1 (de) 1999-07-16 1999-07-21 Füllimplantat für Knorpel- und Knochendefekte in einem Gelenk

Publications (1)

Publication Number Publication Date
WO2001005336A1 true WO2001005336A1 (fr) 2001-01-25

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Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/005556 WO2001005336A1 (fr) 1999-07-16 2000-06-16 Implant destine a remplir des defauts de cartilage et d'os dans les articulations

Country Status (1)

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WO (1) WO2001005336A1 (fr)

Cited By (26)

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USRE43714E1 (en) 1999-12-15 2012-10-02 Zimmer Orthobiologics, Inc. Preparation for repairing cartilage defects or cartilage/bone defects in human or animal joints
US8864827B2 (en) 2000-05-01 2014-10-21 Arthrosurface Inc. System and method for joint resurface repair
WO2014202685A1 (fr) * 2013-06-18 2014-12-24 Ceramtec Gmbh Composants en céramique pour le remplacement de surfaces articulaires
US8926615B2 (en) 2002-12-03 2015-01-06 Arthrosurface, Inc. System and method for retrograde procedure
US8961614B2 (en) 2004-11-22 2015-02-24 Arthrosurface, Inc. Articular surface implant and delivery system
US9044343B2 (en) 2002-12-03 2015-06-02 Arthrosurface Incorporated System for articular surface replacement
US9055955B2 (en) 2000-05-01 2015-06-16 Arthrosurface Inc. Bone resurfacing system and method
US9066716B2 (en) 2011-03-30 2015-06-30 Arthrosurface Incorporated Suture coil and suture sheath for tissue repair
US9204873B2 (en) 2000-05-01 2015-12-08 Arthrosurface Incorporated System and method for joint resurface repair
US9283076B2 (en) 2009-04-17 2016-03-15 Arthrosurface Incorporated Glenoid resurfacing system and method
US9351745B2 (en) 2003-02-24 2016-05-31 Arthrosurface Incorporated Trochlear resurfacing system and method
US9358029B2 (en) 2006-12-11 2016-06-07 Arthrosurface Incorporated Retrograde resection apparatus and method
US9357989B2 (en) 2000-05-01 2016-06-07 Arthrosurface Incorporated System and method for joint resurface repair
US9468448B2 (en) 2012-07-03 2016-10-18 Arthrosurface Incorporated System and method for joint resurfacing and repair
US9492200B2 (en) 2013-04-16 2016-11-15 Arthrosurface Incorporated Suture system and method
WO2016186216A1 (fr) * 2015-05-21 2016-11-24 テルモ株式会社 Élément d'implant
US9662126B2 (en) 2009-04-17 2017-05-30 Arthrosurface Incorporated Glenoid resurfacing system and method
US9861492B2 (en) 2014-03-07 2018-01-09 Arthrosurface Incorporated Anchor for an implant assembly
US10624752B2 (en) 2006-07-17 2020-04-21 Arthrosurface Incorporated Tibial resurfacing system and method
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US9283076B2 (en) 2009-04-17 2016-03-15 Arthrosurface Incorporated Glenoid resurfacing system and method
US11478259B2 (en) 2009-04-17 2022-10-25 Arthrosurface, Incorporated Glenoid resurfacing system and method
US10945743B2 (en) 2009-04-17 2021-03-16 Arthrosurface Incorporated Glenoid repair system and methods of use thereof
US9662126B2 (en) 2009-04-17 2017-05-30 Arthrosurface Incorporated Glenoid resurfacing system and method
US10478200B2 (en) 2009-04-17 2019-11-19 Arthrosurface Incorporated Glenoid resurfacing system and method
US9066716B2 (en) 2011-03-30 2015-06-30 Arthrosurface Incorporated Suture coil and suture sheath for tissue repair
US11712276B2 (en) 2011-12-22 2023-08-01 Arthrosurface Incorporated System and method for bone fixation
US10307172B2 (en) 2012-07-03 2019-06-04 Arthrosurface Incorporated System and method for joint resurfacing and repair
US9468448B2 (en) 2012-07-03 2016-10-18 Arthrosurface Incorporated System and method for joint resurfacing and repair
US11191552B2 (en) 2012-07-03 2021-12-07 Arthrosurface, Incorporated System and method for joint resurfacing and repair
US9492200B2 (en) 2013-04-16 2016-11-15 Arthrosurface Incorporated Suture system and method
US11648036B2 (en) 2013-04-16 2023-05-16 Arthrosurface Incorporated Suture system and method
US10695096B2 (en) 2013-04-16 2020-06-30 Arthrosurface Incorporated Suture system and method
WO2014202685A1 (fr) * 2013-06-18 2014-12-24 Ceramtec Gmbh Composants en céramique pour le remplacement de surfaces articulaires
US10624754B2 (en) 2014-03-07 2020-04-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US11083587B2 (en) 2014-03-07 2021-08-10 Arthrosurface Incorporated Implant and anchor assembly
US10624748B2 (en) 2014-03-07 2020-04-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US9962265B2 (en) 2014-03-07 2018-05-08 Arthrosurface Incorporated System and method for repairing articular surfaces
US9931219B2 (en) 2014-03-07 2018-04-03 Arthrosurface Incorporated Implant and anchor assembly
US11607319B2 (en) 2014-03-07 2023-03-21 Arthrosurface Incorporated System and method for repairing articular surfaces
US10575957B2 (en) 2014-03-07 2020-03-03 Arthrosurface Incoporated Anchor for an implant assembly
US9861492B2 (en) 2014-03-07 2018-01-09 Arthrosurface Incorporated Anchor for an implant assembly
US11766334B2 (en) 2014-03-07 2023-09-26 Arthrosurface Incorporated System and method for repairing articular surfaces
WO2016186216A1 (fr) * 2015-05-21 2016-11-24 テルモ株式会社 Élément d'implant
US11160663B2 (en) 2017-08-04 2021-11-02 Arthrosurface Incorporated Multicomponent articular surface implant
US11478358B2 (en) 2019-03-12 2022-10-25 Arthrosurface Incorporated Humeral and glenoid articular surface implant systems and methods
CN114469252A (zh) * 2021-12-17 2022-05-13 中国人民解放军总医院第四医学中心 一种股骨内侧后髁截骨测量定位系统

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