WO2001004283A3 - Genes et proteines transportant des anions organiques - Google Patents

Genes et proteines transportant des anions organiques Download PDF

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Publication number
WO2001004283A3
WO2001004283A3 PCT/US2000/018980 US0018980W WO0104283A3 WO 2001004283 A3 WO2001004283 A3 WO 2001004283A3 US 0018980 W US0018980 W US 0018980W WO 0104283 A3 WO0104283 A3 WO 0104283A3
Authority
WO
WIPO (PCT)
Prior art keywords
organic anion
polypeptides
human organic
anion transporter
proteins
Prior art date
Application number
PCT/US2000/018980
Other languages
English (en)
Other versions
WO2001004283A2 (fr
WO2001004283A9 (fr
Inventor
William Sun
Original Assignee
Mets Asis Therapeutics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mets Asis Therapeutics Inc filed Critical Mets Asis Therapeutics Inc
Priority to AU60898/00A priority Critical patent/AU6089800A/en
Publication of WO2001004283A2 publication Critical patent/WO2001004283A2/fr
Publication of WO2001004283A3 publication Critical patent/WO2001004283A3/fr
Publication of WO2001004283A9 publication Critical patent/WO2001004283A9/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

L'invention concerne de nouveaux polypeptides humains transportant des anions organiques et les gènes codant ces polypeptides. L'invention a pour objet d'isoler, de caractériser et d'utiliser les polypeptides humains transportant des anions à des fins de criblage pharmacologique de substrats, d'analogues de substrats et de modulateurs de protéines humaines d'anions organiques. L'invention concerne aussi des cultures cellulaires qui contiennent de façon stable des séquences d'acides nucléiques codant pour les polypeptides humains transportant des anions. Ces lignées cellulaires sont utiles pour cribler des composés in vitro afin d'identifier et de caractériser des modulateurs, des inhibiteurs et des substrats de polypeptides humains transportant des anions.
PCT/US2000/018980 1999-07-12 2000-07-12 Genes et proteines transportant des anions organiques WO2001004283A2 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU60898/00A AU6089800A (en) 1999-07-12 2000-07-12 Organic anion transporter genes and proteins

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US14377199P 1999-07-12 1999-07-12
US60/143,771 1999-07-12

Publications (3)

Publication Number Publication Date
WO2001004283A2 WO2001004283A2 (fr) 2001-01-18
WO2001004283A3 true WO2001004283A3 (fr) 2001-07-26
WO2001004283A9 WO2001004283A9 (fr) 2002-05-02

Family

ID=22505543

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/018980 WO2001004283A2 (fr) 1999-07-12 2000-07-12 Genes et proteines transportant des anions organiques

Country Status (2)

Country Link
AU (1) AU6089800A (fr)
WO (1) WO2001004283A2 (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1700866A3 (fr) * 1998-09-18 2006-11-29 Japan Science and Technology Agency Transporteur cérébral organique d'anions et son gène
EP1173457A4 (fr) * 1999-03-04 2005-08-03 Smithkline Beecham Corp Sequences de polynucleotides et de polypeptides codant pour le transporteur de l'anion organique 6(hoatp6) et procede de criblage associe
US20040185527A1 (en) * 2001-01-22 2004-09-23 Gennady Merkulov Isolated human transporter proteins nucleic acid molecules encoding human transporter proteins and uses thereof
JP2003265179A (ja) * 2002-03-14 2003-09-24 Japan Science & Technology Corp 硫酸抱合体を選択的に輸送するトランスポーター及びその遺伝子
WO2005026734A1 (fr) * 2003-09-13 2005-03-24 Bayer Healthcare Ag Diagnostiques et procedes therapeutiques pour des maladies associees a un transporteur slc22a6 de cations organiques (slc22a6)
WO2005026726A1 (fr) * 2003-09-18 2005-03-24 Bayer Healthcare Ag Agents diagnostiques et therapeutiques pour maladies associees au transporteur de cations organiques slc22a7
WO2005026725A1 (fr) * 2003-09-18 2005-03-24 Bayer Healthcare Ag Diagnostics et traitements pour maladies associees au transporteur de cation organique slc22a8 (slc22a8)
WO2005029086A2 (fr) * 2003-09-22 2005-03-31 Bayer Healthcare Ag Agents diagnostiques et therapeutiques pour des maladies liees au transporteur slc22a10 (ust3-like2) (slc22a10) de cations organiques
CN101325940A (zh) * 2005-12-19 2008-12-17 Sca卫生产品股份公司 多构造的吸收制品
JP2009034096A (ja) * 2008-06-12 2009-02-19 J-Pharma Co Ltd 硫酸抱合体を選択的に輸送するトランスポーター及びその遺伝子
US20140090094A1 (en) * 2011-03-09 2014-03-27 Bayer Intellectual Property Gmbh Modulators of slc22a7
PL3736329T3 (pl) * 2012-09-11 2022-07-18 Corning Incorporated Zużywalne krioprezerwowane komórki wykazujące przejściową nadekspresję genu(-ów) kodującego(-ych) białko(-a) transportera leku i/lub enzym(y) metabolizujący(-e) lek

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998053064A1 (fr) * 1997-05-23 1998-11-26 Tanabe Seiyaku Co., Ltd. Transporteur d'anions organiques et gene codant pour ce dernier

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998053064A1 (fr) * 1997-05-23 1998-11-26 Tanabe Seiyaku Co., Ltd. Transporteur d'anions organiques et gene codant pour ce dernier

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL 18 June 1998 (1998-06-18), ROBERT STRAUSBERG: "similar to TR:Q63314 Q63314 LIVER-SPECIFIC TRANSPORT PROTEIN", XP002156222 *
DATABASE EMBL 7 June 1999 (1999-06-07), KIM R.B. ET AL.: "homo sapiens liver-specific transporter (NLT) mRNA, complete cds.", XP002156221 *
KUSUHARA HIROYUKI ET AL: "Molecular cloning and characterization of a new multispecific organic anion transporter from rat brain.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 19, 7 May 1999 (1999-05-07), pages 13675 - 13680, XP002156219, ISSN: 0021-9258 *
SIMONSON GREGG D ET AL: "Molecular cloning and characterization of a novel liver-specific transport protein.", JOURNAL OF CELL SCIENCE, vol. 107, no. 4, 1994, pages 1065 - 1072, XP000971769, ISSN: 0021-9533 *

Also Published As

Publication number Publication date
WO2001004283A2 (fr) 2001-01-18
AU6089800A (en) 2001-01-30
WO2001004283A9 (fr) 2002-05-02

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