WO2001002609A3 - Method of identifying toxic agents using differential gene expression - Google Patents
Method of identifying toxic agents using differential gene expression Download PDFInfo
- Publication number
- WO2001002609A3 WO2001002609A3 PCT/US2000/040292 US0040292W WO0102609A3 WO 2001002609 A3 WO2001002609 A3 WO 2001002609A3 US 0040292 W US0040292 W US 0040292W WO 0102609 A3 WO0102609 A3 WO 0102609A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- gene expression
- differential gene
- toxic agents
- identifying toxic
- identifying
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6809—Methods for determination or identification of nucleic acids involving differential detection
Landscapes
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biotechnology (AREA)
- Physics & Mathematics (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Genetics & Genomics (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001508380A JP2003518365A (en) | 1999-07-02 | 2000-06-30 | Methods for identifying virulence factors using differential gene expression |
EP00960121A EP1255857A2 (en) | 1999-07-02 | 2000-06-30 | Method of identifying toxic agents using differential gene expression |
CA002377768A CA2377768A1 (en) | 1999-07-02 | 2000-06-30 | Method of identifying toxic agents using differential gene expression |
AU71330/00A AU7133000A (en) | 1999-07-02 | 2000-06-30 | Method of identifying toxic agents using differential gene expression |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US14233599P | 1999-07-02 | 1999-07-02 | |
US60/142,335 | 1999-07-02 | ||
US60753900A | 2000-06-29 | 2000-06-29 | |
US09/607,539 | 2000-06-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001002609A2 WO2001002609A2 (en) | 2001-01-11 |
WO2001002609A3 true WO2001002609A3 (en) | 2002-09-12 |
Family
ID=26840003
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/040292 WO2001002609A2 (en) | 1999-07-02 | 2000-06-30 | Method of identifying toxic agents using differential gene expression |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP1255857A2 (en) |
JP (1) | JP2003518365A (en) |
AU (1) | AU7133000A (en) |
CA (1) | CA2377768A1 (en) |
WO (1) | WO2001002609A2 (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9555148B2 (en) | 2011-11-17 | 2017-01-31 | Evonik Degussa Gmbh | Superabsorbing polymers with rapid absorption properties and method for producing the same |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2369969A1 (en) * | 1999-04-15 | 2000-10-26 | Curagen Corporation | Method of identifying toxic agents using differential gene expression |
EP1255857A2 (en) * | 1999-07-02 | 2002-11-13 | Curagen Corporation | Method of identifying toxic agents using differential gene expression |
US7415358B2 (en) | 2001-05-22 | 2008-08-19 | Ocimum Biosolutions, Inc. | Molecular toxicology modeling |
US7469185B2 (en) | 2002-02-04 | 2008-12-23 | Ocimum Biosolutions, Inc. | Primary rat hepatocyte toxicity modeling |
EP1344834A3 (en) * | 2002-03-14 | 2004-06-02 | F. Hoffmann-La Roche Ag | Methods for the toxicity prediction of a compound |
WO2005014793A2 (en) * | 2003-08-07 | 2005-02-17 | Gene Logic, Inc. | Primary rat hepatocyte toxicity modeling |
US9302248B2 (en) | 2013-04-10 | 2016-04-05 | Evonik Corporation | Particulate superabsorbent polymer composition having improved stability |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997013877A1 (en) * | 1995-10-12 | 1997-04-17 | Lynx Therapeutics, Inc. | Measurement of gene expression profiles in toxicity determination |
WO1998013353A1 (en) * | 1996-09-26 | 1998-04-02 | Aurora Biosciences Corporation | Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and use for cellular assays in drug discovery |
WO2001002609A2 (en) * | 1999-07-02 | 2001-01-11 | Curagen Corporation | Method of identifying toxic agents using differential gene expression |
WO2001032928A2 (en) * | 1999-11-05 | 2001-05-10 | Phase-1 Molecular Toxicology | Methods of determining individual hypersensitivity to an agent |
WO2001051638A2 (en) * | 2000-01-14 | 2001-07-19 | Incyte Genomics, Inc. | Drug metabolizing enzymes |
WO2001053514A1 (en) * | 2000-01-21 | 2001-07-26 | Glaxo Group Limited | Toxicant-induced differential gene expression |
-
2000
- 2000-06-30 EP EP00960121A patent/EP1255857A2/en not_active Withdrawn
- 2000-06-30 WO PCT/US2000/040292 patent/WO2001002609A2/en not_active Application Discontinuation
- 2000-06-30 JP JP2001508380A patent/JP2003518365A/en not_active Withdrawn
- 2000-06-30 AU AU71330/00A patent/AU7133000A/en not_active Abandoned
- 2000-06-30 CA CA002377768A patent/CA2377768A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997013877A1 (en) * | 1995-10-12 | 1997-04-17 | Lynx Therapeutics, Inc. | Measurement of gene expression profiles in toxicity determination |
WO1998013353A1 (en) * | 1996-09-26 | 1998-04-02 | Aurora Biosciences Corporation | Methods and compositions for sensitive and rapid, functional identification of genomic polynucleotides and use for cellular assays in drug discovery |
WO2001002609A2 (en) * | 1999-07-02 | 2001-01-11 | Curagen Corporation | Method of identifying toxic agents using differential gene expression |
WO2001032928A2 (en) * | 1999-11-05 | 2001-05-10 | Phase-1 Molecular Toxicology | Methods of determining individual hypersensitivity to an agent |
WO2001051638A2 (en) * | 2000-01-14 | 2001-07-19 | Incyte Genomics, Inc. | Drug metabolizing enzymes |
WO2001053514A1 (en) * | 2000-01-21 | 2001-07-26 | Glaxo Group Limited | Toxicant-induced differential gene expression |
Non-Patent Citations (2)
Title |
---|
DATABASE BIOSIS [online] BIOSCIENCES INFORMATION SERVICE, PHILADELPHIA, PA, US; 1988, MEYERS L L ET AL: "ACETAMINOPHEN-INDUCED INHIBITION OF HEPATIC MITOCHONDRIAL RESPIRATION IN MICE", XP002179998, Database accession no. PREV198886033625 * |
TOXICOLOGY AND APPLIED PHARMACOLOGY, vol. 93, no. 3, 1988, pages 378 - 387, ISSN: 0041-008X * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US9555148B2 (en) | 2011-11-17 | 2017-01-31 | Evonik Degussa Gmbh | Superabsorbing polymers with rapid absorption properties and method for producing the same |
Also Published As
Publication number | Publication date |
---|---|
WO2001002609A2 (en) | 2001-01-11 |
CA2377768A1 (en) | 2001-01-11 |
EP1255857A2 (en) | 2002-11-13 |
AU7133000A (en) | 2001-01-22 |
JP2003518365A (en) | 2003-06-10 |
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