WO2001000801A3 - Gene involved in epigenetic gene silencing - Google Patents

Gene involved in epigenetic gene silencing Download PDF

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Publication number
WO2001000801A3
WO2001000801A3 PCT/EP2000/005761 EP0005761W WO0100801A3 WO 2001000801 A3 WO2001000801 A3 WO 2001000801A3 EP 0005761 W EP0005761 W EP 0005761W WO 0100801 A3 WO0100801 A3 WO 0100801A3
Authority
WO
WIPO (PCT)
Prior art keywords
gene
epigenetic
involved
amino acid
silencing
Prior art date
Application number
PCT/EP2000/005761
Other languages
French (fr)
Other versions
WO2001000801A2 (en
Inventor
Yoshiki Habu
Scheid Ortrun Mittelsten
Paolo Amedeo
Jerzy Paszkowski
Original Assignee
Syngenta Participations Ag
Novartis Erfind Verwalt Gmbh
Yoshiki Habu
Scheid Ortrun Mittelsten
Paolo Amedeo
Jerzy Paszkowski
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syngenta Participations Ag, Novartis Erfind Verwalt Gmbh, Yoshiki Habu, Scheid Ortrun Mittelsten, Paolo Amedeo, Jerzy Paszkowski filed Critical Syngenta Participations Ag
Priority to AU59770/00A priority Critical patent/AU5977000A/en
Priority to EP00945801A priority patent/EP1185657A2/en
Priority to CA002369749A priority patent/CA2369749A1/en
Priority to JP2001506795A priority patent/JP2003503047A/en
Publication of WO2001000801A2 publication Critical patent/WO2001000801A2/en
Publication of WO2001000801A3 publication Critical patent/WO2001000801A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/415—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from plants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8216—Methods for controlling, regulating or enhancing expression of transgenes in plant cells
    • C12N15/8218—Antisense, co-suppression, viral induced gene silencing [VIGS], post-transcriptional induced gene silencing [PTGS]

Landscapes

  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Plant Pathology (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Botany (AREA)
  • Virology (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to DNA which encodes proteins involved in gene silencing. Related genes encoding proteins characterized by an amino acid sequence comprising a component sequence of at least 150 amino acid residues having 40% or more identity with an alinged component sequence of SEQ ID NO:3 can be isolated from different sources such as mammalian or plant cells. Further disclosed is a method for isolating DNA according to the invention.
PCT/EP2000/005761 1999-06-23 2000-06-21 Gene involved in epigenetic gene silencing WO2001000801A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU59770/00A AU5977000A (en) 1999-06-23 2000-06-21 Gene involved in epigenetic gene silencing
EP00945801A EP1185657A2 (en) 1999-06-23 2000-06-21 Gene involved in epigenetic gene silencing
CA002369749A CA2369749A1 (en) 1999-06-23 2000-06-21 Gene involved in epigenetic gene silencing
JP2001506795A JP2003503047A (en) 1999-06-23 2000-06-21 Genes involved in epigenetic gene silencing

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9914623.5 1999-06-23
GBGB9914623.5A GB9914623D0 (en) 1999-06-23 1999-06-23 Organic compounds

Publications (2)

Publication Number Publication Date
WO2001000801A2 WO2001000801A2 (en) 2001-01-04
WO2001000801A3 true WO2001000801A3 (en) 2001-05-10

Family

ID=10855867

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/005761 WO2001000801A2 (en) 1999-06-23 2000-06-21 Gene involved in epigenetic gene silencing

Country Status (8)

Country Link
EP (1) EP1185657A2 (en)
JP (1) JP2003503047A (en)
CN (1) CN1250724C (en)
AR (1) AR024421A1 (en)
AU (1) AU5977000A (en)
CA (1) CA2369749A1 (en)
GB (1) GB9914623D0 (en)
WO (1) WO2001000801A2 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE112008000521T5 (en) * 2007-02-28 2010-03-04 Cropdesign N.V. Plants with improved yield-related traits and methods for their production

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998004725A1 (en) * 1996-07-31 1998-02-05 Yale University Methods for altering the rate of plant development and plants obtained therefrom

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998004725A1 (en) * 1996-07-31 1998-02-05 Yale University Methods for altering the rate of plant development and plants obtained therefrom

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
AMEDEO PAOLO ET AL: "Disruption of the plant gene MOM releases transcriptional silencing of methylated genes.", NATURE (LONDON), vol. 405, no. 6783, 11 May 2000 (2000-05-11), pages 203 - 206, XP002159059, ISSN: 0028-0836 *
DATABASE EMGSS_PLN2 EMBL Heidelberg, Germany; 20 September 1997 (1997-09-20), FENG J ET AL.: "BAC end sequences at ATGC", XP002159060 *
DATABASE EMGSS_PLN2 EMBL Heidelberg, Germany; 9 December 1997 (1997-12-09), ROUNSLEY S D ET AL.: "A BAC end sequence database for identifying minimal overlaps in Arabidopsis genomic sequencing", XP002159061 *
MITTELSTEN-SCHEID ET AL: "Release of epigenetic gene silencing by trans-acting mutations in Arabidopsis", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF USA,NATIONAL ACADEMY OF SCIENCE. WASHINGTON,US, vol. 95, January 1998 (1998-01-01), pages 632 - 637, XP002114098, ISSN: 0027-8424 *
PASZKOWSKI ET AL: "Plant genes: the genetics of epigenetics", CURRENT BIOLOGY,GB,CURRENT SCIENCE,, vol. 8, no. 6, 12 March 1998 (1998-03-12), pages 206 - 208-R208, XP002114102, ISSN: 0960-9822 *
See also references of EP1185657A2 *

Also Published As

Publication number Publication date
JP2003503047A (en) 2003-01-28
AR024421A1 (en) 2002-10-02
EP1185657A2 (en) 2002-03-13
GB9914623D0 (en) 1999-08-25
AU5977000A (en) 2001-01-31
CN1250724C (en) 2006-04-12
WO2001000801A2 (en) 2001-01-04
CA2369749A1 (en) 2001-01-04
CN1364194A (en) 2002-08-14

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