WO2000074663A3 - Use of allicin for control of weight in mammals - Google Patents

Use of allicin for control of weight in mammals Download PDF

Info

Publication number
WO2000074663A3
WO2000074663A3 PCT/IL2000/000323 IL0000323W WO0074663A3 WO 2000074663 A3 WO2000074663 A3 WO 2000074663A3 IL 0000323 W IL0000323 W IL 0000323W WO 0074663 A3 WO0074663 A3 WO 0074663A3
Authority
WO
WIPO (PCT)
Prior art keywords
weight
allicin
mammals
control
prevention
Prior art date
Application number
PCT/IL2000/000323
Other languages
French (fr)
Other versions
WO2000074663A2 (en
Inventor
Talma Rosenthal
Amitai Elkayam
Meir Wilchek
Talia Miron
Edna Peleg
Aharon Rabinkov
David Mirelman
Original Assignee
Yeda Res & Dev
Univ Ramot
Talma Rosenthal
Amitai Elkayam
Meir Wilchek
Talia Miron
Edna Peleg
Aharon Rabinkov
David Mirelman
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yeda Res & Dev, Univ Ramot, Talma Rosenthal, Amitai Elkayam, Meir Wilchek, Talia Miron, Edna Peleg, Aharon Rabinkov, David Mirelman filed Critical Yeda Res & Dev
Priority to AU49474/00A priority Critical patent/AU4947400A/en
Publication of WO2000074663A2 publication Critical patent/WO2000074663A2/en
Publication of WO2000074663A3 publication Critical patent/WO2000074663A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197—Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
    • A61K31/198—Alpha-amino acids, e.g. alanine or edetic acid [EDTA]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255—Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Steroid Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

Allicin is used for control of weight in mammals, in particular for reduction of weight and/or prevention of weight gain, more particularly for prevention of weight gain in an individual who has previously undergone a diet for reducing weight.
PCT/IL2000/000323 1999-06-07 2000-06-05 Use of allicin for control of weight in mammals WO2000074663A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU49474/00A AU4947400A (en) 1999-06-07 2000-06-05 Use of allicin for control of weight in mammals

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IL13032599A IL130325A0 (en) 1999-06-07 1999-06-07 Pharmaceutical compositions comprising allicin
IL130325 1999-06-07

Publications (2)

Publication Number Publication Date
WO2000074663A2 WO2000074663A2 (en) 2000-12-14
WO2000074663A3 true WO2000074663A3 (en) 2001-08-02

Family

ID=11072889

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IL2000/000323 WO2000074663A2 (en) 1999-06-07 2000-06-05 Use of allicin for control of weight in mammals

Country Status (3)

Country Link
AU (1) AU4947400A (en)
IL (1) IL130325A0 (en)
WO (1) WO2000074663A2 (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2625201A (en) 2000-01-03 2001-07-16 Ramot University Authority For Applied Research And Industrial Development Ltd. Glycogen synthase kinase-3 inhibitors
US7378432B2 (en) 2001-09-14 2008-05-27 Tel Aviv University Future Technology Development L.P. Glycogen synthase kinase-3 inhibitors
EP1569956B1 (en) 2002-12-12 2014-02-26 Tel Aviv University Future Technology Development L.P. Glycogen synthase kinase-3 inhibitors
CA2610922A1 (en) * 2005-06-13 2006-12-21 Yeda Research And Development Co. Ltd. Use of allylmercaptocaptopril for treating or preventing obesity and obesity related diseases
CN100389760C (en) * 2006-04-18 2008-05-28 张国清 Enteric coated drop pills of garlicin, and preparation method

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6261925A (en) * 1985-09-10 1987-03-18 Riken Kagaku Kogyo Kk Lipid metabolism promoting agent
EP0232501A1 (en) * 1985-12-19 1987-08-19 Chimicasa Gmbh Pharmaceutical preparation for the treatment of lipid metabolism disorders (hyperlipoproteinemia)
JPH04338336A (en) * 1991-05-15 1992-11-25 Riken Health Kk Antiobesitic agent
JPH05268906A (en) * 1991-09-17 1993-10-19 Michiyasu Hamaya Health food
JPH07304683A (en) * 1994-05-09 1995-11-21 Riken Health Kk Lipid metabolism-promoting agent
WO1997039115A1 (en) * 1996-04-16 1997-10-23 Yeda Research And Development Co. Ltd. Immobilized alliinase and continuous production of allicin

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6261925A (en) * 1985-09-10 1987-03-18 Riken Kagaku Kogyo Kk Lipid metabolism promoting agent
EP0232501A1 (en) * 1985-12-19 1987-08-19 Chimicasa Gmbh Pharmaceutical preparation for the treatment of lipid metabolism disorders (hyperlipoproteinemia)
JPH04338336A (en) * 1991-05-15 1992-11-25 Riken Health Kk Antiobesitic agent
JPH05268906A (en) * 1991-09-17 1993-10-19 Michiyasu Hamaya Health food
JPH07304683A (en) * 1994-05-09 1995-11-21 Riken Health Kk Lipid metabolism-promoting agent
WO1997039115A1 (en) * 1996-04-16 1997-10-23 Yeda Research And Development Co. Ltd. Immobilized alliinase and continuous production of allicin

Non-Patent Citations (6)

* Cited by examiner, † Cited by third party
Title
K.T. AUGUSTI ET AL: "Lipid lowering effect of allicin (diallyldisulphide-oxide ON Lon long term feeding to normal rats", EXPERIENTIA., vol. 30, no. 5, 1974, BIRKHAUSER VERLAG. BASEL., CH, pages 468 - 470, XP000979572, ISSN: 0014-4754 *
PATENT ABSTRACTS OF JAPAN vol. 011, no. 259 (C - 441) 21 August 1987 (1987-08-21) *
PATENT ABSTRACTS OF JAPAN vol. 017, no. 185 (C - 1047) 12 April 1993 (1993-04-12) *
PATENT ABSTRACTS OF JAPAN vol. 018, no. 040 (C - 1155) 21 January 1994 (1994-01-21) *
PATENT ABSTRACTS OF JAPAN vol. 1996, no. 03 29 March 1996 (1996-03-29) *
YOON SHIK LEE: "A comparative study of the effect of allicin and arsenite on albino rats with special regard to the effect on body weight, hemoglobin, and hepatic histology", NEW MEDICAL JOURNAL, no. 1, 1967, seoul, korea, pages 99 - 101, XP000983088 *

Also Published As

Publication number Publication date
IL130325A0 (en) 2000-06-01
WO2000074663A2 (en) 2000-12-14
AU4947400A (en) 2000-12-28

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