WO2000071157A3 - Nouvelles preparations vaccinales - 1 - Google Patents

Nouvelles preparations vaccinales - 1

Info

Publication number
WO2000071157A3
WO2000071157A3 PCT/GB2000/001938 GB0001938W WO0071157A3 WO 2000071157 A3 WO2000071157 A3 WO 2000071157A3 GB 0001938 W GB0001938 W GB 0001938W WO 0071157 A3 WO0071157 A3 WO 0071157A3
Authority
WO
WIPO (PCT)
Prior art keywords
relates
vaccines
culture techniques
cancer
vaccine formulations
Prior art date
Application number
PCT/GB2000/001938
Other languages
English (en)
Other versions
WO2000071157A2 (fr
Inventor
Andrew Sutton
Peter Smith
Darren Stevenson
Haj Chana
Original Assignee
Onyvax Ltd
Andrew Sutton
Peter Smith
Darren Stevenson
Haj Chana
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Onyvax Ltd, Andrew Sutton, Peter Smith, Darren Stevenson, Haj Chana filed Critical Onyvax Ltd
Priority to EP00935287A priority Critical patent/EP1178823A2/fr
Priority to AU50843/00A priority patent/AU5084300A/en
Priority to CA002373730A priority patent/CA2373730A1/fr
Publication of WO2000071157A2 publication Critical patent/WO2000071157A2/fr
Publication of WO2000071157A3 publication Critical patent/WO2000071157A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0693—Tumour cells; Cancer cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/515—Animal cells
    • A61K2039/5152—Tumor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/80—Vaccine for a specifically defined cancer
    • A61K2039/884—Vaccine for a specifically defined cancer prostate
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2513/00—3D culture

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • General Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Oncology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

L'invention concerne de nouveaux vaccins utilisés comme agents immunothérapiques dans le traitement de cancer plus particulièrement celui de la prostate, mais pas uniquement. En outre, l'invention concerne diverses techniques de culture offrant des mises à l'échelle améliorées et des avantages de traitement, et améliorant de manière significative l'activité des vaccins à base de cellules allogéniques entières ou de leurs dérivés. L'invention concerne également une méthode de production de vaccins contre le cancer, à base de cellules entières, ainsi que la culture de cellules malignes dans des conditions de techniques de culture 2D statiques non conventionnelles.
PCT/GB2000/001938 1999-05-21 2000-05-19 Nouvelles preparations vaccinales - 1 WO2000071157A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP00935287A EP1178823A2 (fr) 1999-05-21 2000-05-19 Nouvelles preparations vaccinales - 1
AU50843/00A AU5084300A (en) 1999-05-21 2000-05-19 New vaccine formulations - 1
CA002373730A CA2373730A1 (fr) 1999-05-21 2000-05-19 Nouvelles preparations vaccinales - 1

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9911823.4 1999-05-21
GBGB9911823.4A GB9911823D0 (en) 1999-05-21 1999-05-21 New vaccine formulations

Publications (2)

Publication Number Publication Date
WO2000071157A2 WO2000071157A2 (fr) 2000-11-30
WO2000071157A3 true WO2000071157A3 (fr) 2001-04-12

Family

ID=10853879

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/001938 WO2000071157A2 (fr) 1999-05-21 2000-05-19 Nouvelles preparations vaccinales - 1

Country Status (5)

Country Link
EP (1) EP1178823A2 (fr)
AU (1) AU5084300A (fr)
CA (1) CA2373730A1 (fr)
GB (1) GB9911823D0 (fr)
WO (1) WO2000071157A2 (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1293212A1 (fr) * 2001-08-21 2003-03-19 National Research Council Of Canada Vaccin contre le cancer comprenant des cellules cancéreuses entières ayant un acide sialique modifié
WO2012158989A2 (fr) * 2011-05-19 2012-11-22 The Regents Of The University Of Michigan Agents se liant à l'intégrine alpha-2 et leur utilisation pour inhiber la prolifération des cellules cancéreuses

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997024132A1 (fr) * 1995-12-28 1997-07-10 The Johns Hopkins University School Of Medicine Vaccins a base de tumeurs de cytokine paracrine allogenique
WO1997028255A1 (fr) * 1996-02-02 1997-08-07 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Lignees de cellules epitheliales immortalisees provenant de prostate d'origine humaine, clones correspondants et leurs applications s'agissant de recherche et de therapie du cancer de la prostate
US5804443A (en) * 1997-02-28 1998-09-08 Bernofsky; Carl Human monocytic leukemia cell line

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997024132A1 (fr) * 1995-12-28 1997-07-10 The Johns Hopkins University School Of Medicine Vaccins a base de tumeurs de cytokine paracrine allogenique
WO1997028255A1 (fr) * 1996-02-02 1997-08-07 The Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Lignees de cellules epitheliales immortalisees provenant de prostate d'origine humaine, clones correspondants et leurs applications s'agissant de recherche et de therapie du cancer de la prostate
US5804443A (en) * 1997-02-28 1998-09-08 Bernofsky; Carl Human monocytic leukemia cell line

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
FRESHNEY R. I.: "Culture of animal cells", 1987, ALAN R. LISS, US, NEW YORK, XP002152704, 154920 *

Also Published As

Publication number Publication date
EP1178823A2 (fr) 2002-02-13
WO2000071157A2 (fr) 2000-11-30
CA2373730A1 (fr) 2000-11-30
AU5084300A (en) 2000-12-12
GB9911823D0 (en) 1999-07-21

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