WO2000068234A3 - Process for the preparation of cefpodoxime acid - Google Patents

Process for the preparation of cefpodoxime acid Download PDF

Info

Publication number
WO2000068234A3
WO2000068234A3 PCT/IB2000/000585 IB0000585W WO0068234A3 WO 2000068234 A3 WO2000068234 A3 WO 2000068234A3 IB 0000585 W IB0000585 W IB 0000585W WO 0068234 A3 WO0068234 A3 WO 0068234A3
Authority
WO
WIPO (PCT)
Prior art keywords
preparation
cefpodoxime
cefpodoxime acid
acid
converted
Prior art date
Application number
PCT/IB2000/000585
Other languages
French (fr)
Other versions
WO2000068234A2 (en
Inventor
Yatendra Kumar
Rakesh Kumar Arora
Kaptan Singh
Hashim Nizar
Shantanu De
Jag Mohan Khanna
Original Assignee
Ranbaxy Lab Ltd
Yatendra Kumar
Rakesh Kumar Arora
Kaptan Singh
Hashim Nizar
Shantanu De
Jag Mohan Khanna
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ranbaxy Lab Ltd, Yatendra Kumar, Rakesh Kumar Arora, Kaptan Singh, Hashim Nizar, Shantanu De, Jag Mohan Khanna filed Critical Ranbaxy Lab Ltd
Priority to EP00969048A priority Critical patent/EP1178992A2/en
Priority to AU72243/00A priority patent/AU7224300A/en
Publication of WO2000068234A2 publication Critical patent/WO2000068234A2/en
Publication of WO2000068234A3 publication Critical patent/WO2000068234A3/en
Priority to HK02105883.7A priority patent/HK1044761A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)

Abstract

A new process is described for the preparation of cefpodoxime acid, which may then be converted into cefpodoxime proxetil by methods known in the art.
PCT/IB2000/000585 1999-05-07 2000-05-05 Process for the preparation of cefpodoxime acid WO2000068234A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP00969048A EP1178992A2 (en) 1999-05-07 2000-05-05 Process for the preparation of cefpodoxime acid
AU72243/00A AU7224300A (en) 1999-05-07 2000-05-05 Process for the preparation of cefpodoxime acid
HK02105883.7A HK1044761A1 (en) 1999-05-07 2002-08-12 Process for the preparation of cefpodoxime acid

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30701099A 1999-05-07 1999-05-07
US09/307,010 1999-05-07

Publications (2)

Publication Number Publication Date
WO2000068234A2 WO2000068234A2 (en) 2000-11-16
WO2000068234A3 true WO2000068234A3 (en) 2001-02-08

Family

ID=23187851

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB2000/000585 WO2000068234A2 (en) 1999-05-07 2000-05-05 Process for the preparation of cefpodoxime acid

Country Status (4)

Country Link
EP (1) EP1178992A2 (en)
AU (1) AU7224300A (en)
HK (1) HK1044761A1 (en)
WO (1) WO2000068234A2 (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004037833A1 (en) * 2002-10-24 2004-05-06 Orchid Chemicals & Pharmaceuticals Ltd Process for the preparation of cephalosporin antibiotics
WO2011077217A1 (en) * 2009-12-21 2011-06-30 Nectar Lifesciences Ltd. An improved process for the preparation of cefpodoxime acid
CN106046024B (en) * 2016-06-30 2019-01-15 齐鲁动物保健品有限公司 A kind of preparation method of Cefpodoxime Proxetil
CN111320514A (en) * 2020-04-03 2020-06-23 南京昊绿生物科技有限公司 Synthesis method of cefpodoxime D3

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034536A2 (en) * 1980-02-18 1981-08-26 Roussel-Uclaf Oxime derivatives of 3-alkyloxy- or 3-alkylthiomethyl 7-amino-thiazolylacetamido cephalosporanic acid, their preparation, their use as medicaments and compositions containing them
JPS60260583A (en) * 1985-05-14 1985-12-23 Sankyo Co Ltd Preparation of cephalosporin derivative
JPS60260584A (en) * 1985-05-14 1985-12-23 Sankyo Co Ltd Cephalosporin derivative and its preparation
EP0531875A2 (en) * 1991-09-07 1993-03-17 Hoechst Aktiengesellschaft Diastereomers of the 3-cephem-4-carboxylic acid-1-(-isopropoxycarbonyloxy)ethylester and process for their preparation

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CY1365A (en) 1980-03-28 1987-08-07 Biochemie Gmbh New process for the production of cephalosporin antibiotics, and novel intermediates used in such process and their production
TW538045B (en) 1997-01-16 2003-06-21 Biochemie Gmbh Process for purifying cefixime

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0034536A2 (en) * 1980-02-18 1981-08-26 Roussel-Uclaf Oxime derivatives of 3-alkyloxy- or 3-alkylthiomethyl 7-amino-thiazolylacetamido cephalosporanic acid, their preparation, their use as medicaments and compositions containing them
US4992431A (en) * 1980-02-18 1991-02-12 Rousseluclaf Cephalosporins
JPS60260583A (en) * 1985-05-14 1985-12-23 Sankyo Co Ltd Preparation of cephalosporin derivative
JPS60260584A (en) * 1985-05-14 1985-12-23 Sankyo Co Ltd Cephalosporin derivative and its preparation
EP0531875A2 (en) * 1991-09-07 1993-03-17 Hoechst Aktiengesellschaft Diastereomers of the 3-cephem-4-carboxylic acid-1-(-isopropoxycarbonyloxy)ethylester and process for their preparation

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
CHEMICAL ABSTRACTS, vol. 108, no. 5, 1 February 1988, Columbus, Ohio, US; abstract no. 55704m, FUJIMOTO K ET AL: "Studies on orally active cephalosporin esters" page 687; column 2; XP002901354 *
J. ANTIBIOT., vol. 40, no. 3, 1987, pages 370 - 384 *
PATENT ABSTRACTS OF JAPAN vol. 010, no. 136 (C - 347) 20 May 1986 (1986-05-20) *
See also references of EP1178992A2 *

Also Published As

Publication number Publication date
WO2000068234A2 (en) 2000-11-16
EP1178992A2 (en) 2002-02-13
HK1044761A1 (en) 2002-11-01
AU7224300A (en) 2000-11-21

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