WO2000067774A3 - Materials for soft tissue augmentation and methods of making and using same - Google Patents

Materials for soft tissue augmentation and methods of making and using same Download PDF

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Publication number
WO2000067774A3
WO2000067774A3 PCT/US2000/010022 US0010022W WO0067774A3 WO 2000067774 A3 WO2000067774 A3 WO 2000067774A3 US 0010022 W US0010022 W US 0010022W WO 0067774 A3 WO0067774 A3 WO 0067774A3
Authority
WO
WIPO (PCT)
Prior art keywords
materials
soft tissue
tissue augmentation
making
methods
Prior art date
Application number
PCT/US2000/010022
Other languages
French (fr)
Other versions
WO2000067774A2 (en
Inventor
Norman Orentreich
Rozlyn A Krajcik
Original Assignee
Orentreich Foundation For The
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Orentreich Foundation For The filed Critical Orentreich Foundation For The
Priority to CA002371265A priority Critical patent/CA2371265A1/en
Priority to AU43488/00A priority patent/AU4348800A/en
Priority to EP00923345A priority patent/EP1178816B1/en
Priority to DE60028965T priority patent/DE60028965T2/en
Publication of WO2000067774A2 publication Critical patent/WO2000067774A2/en
Publication of WO2000067774A3 publication Critical patent/WO2000067774A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/16—Blood plasma; Blood serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/1703—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • A61K38/1709—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Epidemiology (AREA)
  • Hematology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Dermatology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Treatment Of Fiber Materials (AREA)
  • Treatments For Attaching Organic Compounds To Fibrous Goods (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Materials for soft tissue augmentation in mammals are prepared bycross-linking blood plasma proteins, preferably with a zero-length cross-linking agent. The cross-linked blood plasma proteins canbe dialyzed and autoclaved. Such materials are non-antigenic, exhibit decreased allergic response, and have increased longevity with respect to proteolytic attack from natural proteases. The appearance and/or feel of soft tissue defects and/or imperfections in skin can be improved by injecting such materials into an intradermal compartment of a patient's skin.
PCT/US2000/010022 1999-05-11 2000-04-13 Materials for soft tissue augmentation and methods of making and using same WO2000067774A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002371265A CA2371265A1 (en) 1999-05-11 2000-04-13 Materials for soft tissue augmentation and methods of making and using same
AU43488/00A AU4348800A (en) 1999-05-11 2000-04-13 Materials for soft tissue augmentation and methods of making and using same
EP00923345A EP1178816B1 (en) 1999-05-11 2000-04-13 Materials for soft tissue augmentation and methods of making and using same
DE60028965T DE60028965T2 (en) 1999-05-11 2000-04-13 MATERIALS FOR THE REPRODUCTION OF SOFT FABRICS AND THEIR MANUFACTURING AND USE METHODS

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/309,689 1999-05-11
US09/309,689 US7015198B1 (en) 1999-05-11 1999-05-11 Materials for soft tissue augmentation and methods of making and using same

Publications (2)

Publication Number Publication Date
WO2000067774A2 WO2000067774A2 (en) 2000-11-16
WO2000067774A3 true WO2000067774A3 (en) 2001-02-08

Family

ID=23199244

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/010022 WO2000067774A2 (en) 1999-05-11 2000-04-13 Materials for soft tissue augmentation and methods of making and using same

Country Status (7)

Country Link
US (1) US7015198B1 (en)
EP (1) EP1178816B1 (en)
AT (1) ATE330621T1 (en)
AU (1) AU4348800A (en)
CA (1) CA2371265A1 (en)
DE (1) DE60028965T2 (en)
WO (1) WO2000067774A2 (en)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070078435A1 (en) * 2001-06-14 2007-04-05 Corbett Stone Tissue augmentation methods using a medical injection apparatus
WO2003094937A1 (en) * 2002-05-09 2003-11-20 Medigenes A pharmaceutical composition for treatment of wounds containing blood plasma or serum
US20050276863A1 (en) * 2004-05-27 2005-12-15 Medtronic Vascular, Inc. Methods for treatment of aneurysmal tissue
US20070102010A1 (en) * 2005-10-07 2007-05-10 Lemperle Stefan M Naso-pharyngeal tissue engineering
DK2049560T3 (en) 2006-07-13 2013-07-29 Novozymes Biopharma Dk As Process for the preparation of particles of proteinaceous material
WO2009051701A2 (en) * 2007-10-15 2009-04-23 Wake Forest University Health Sciences Methods and compositions for printing biologically compatible nanotube composites of autologous tissue
WO2010028025A1 (en) 2008-09-02 2010-03-11 Gurtner Geoffrey C Threads of hyaluronic acid and/or derivatives thereof, methods of making thereof and uses thereof
US9101538B2 (en) 2009-05-20 2015-08-11 Donna M. Tozzi Injectable amino-acid composition
US20100297182A1 (en) * 2009-05-20 2010-11-25 Tozzi Donna M Injectable Amino-acid Composition
US20110172180A1 (en) 2010-01-13 2011-07-14 Allergan Industrie. Sas Heat stable hyaluronic acid compositions for dermatological use
DK2550027T4 (en) * 2010-03-22 2019-05-13 Allergan Inc CROSS-BAND POLYSACCHARID AND PROTEIN POLYSACCHARID HYDROCHLORIC PRODUCTS
WO2012167079A2 (en) 2011-06-03 2012-12-06 Allergan, Inc. Dermal filler compositions including antioxidants
US9393263B2 (en) 2011-06-03 2016-07-19 Allergan, Inc. Dermal filler compositions including antioxidants
US20130096081A1 (en) 2011-06-03 2013-04-18 Allergan, Inc. Dermal filler compositions
US9408797B2 (en) 2011-06-03 2016-08-09 Allergan, Inc. Dermal filler compositions for fine line treatment
US20130244943A1 (en) 2011-09-06 2013-09-19 Allergan, Inc. Hyaluronic acid-collagen matrices for dermal filling and volumizing applications
US9662422B2 (en) 2011-09-06 2017-05-30 Allergan, Inc. Crosslinked hyaluronic acid-collagen gels for improving tissue graft viability and soft tissue augmentation
ES2527967B1 (en) * 2013-08-01 2015-12-28 Biotechnology Institute, I Mas D, S.L. Formulation of a blood composition rich in platelets and / or growth factors, with gelled proteins and method of preparation thereof
ES2761558T3 (en) 2014-09-30 2020-05-20 Allergan Ind Sas Stable hydrogel compositions including additives

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1013577A (en) * 1962-05-11 1965-12-15 Biotest Serum Institut Gmbh A process for the modification of proteins
US5733545A (en) * 1995-03-03 1998-03-31 Quantic Biomedical Partners Platelet glue wound sealant
US5804428A (en) * 1992-10-08 1998-09-08 Bristol-Myers Squibb Company Fibrin sealant compositions and methods for utilizing same

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3152976A (en) 1961-09-21 1964-10-13 Ethicon Inc Preparation of collagenous materials
US4046871A (en) * 1975-04-08 1977-09-06 Ortho Diagnostics Inc. Compositions and serological methods including bovine serum albumin polymers
US4006220A (en) 1975-06-04 1977-02-01 Gottlieb Sheldon K Compositions and methods useful for repairing depressed cutaneous scars
US4404970A (en) 1978-05-19 1983-09-20 Sawyer Philip Nicholas Hemostatic article and methods for preparing and employing the same
US5628781A (en) 1985-06-06 1997-05-13 Thomas Jefferson University Implant materials, methods of treating the surface of implants with microvascular endothelial cells, and the treated implants themselves
US5147514A (en) 1987-08-02 1992-09-15 University Of North Carolina Process for cross-linking collagenous material and resulting product
US4969912A (en) 1988-02-18 1990-11-13 Kelman Charles D Human collagen processing and autoimplant use
US5162430A (en) 1988-11-21 1992-11-10 Collagen Corporation Collagen-polymer conjugates
US5550187A (en) 1988-11-21 1996-08-27 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
US5527856A (en) 1988-11-21 1996-06-18 Collagen Corporation Method of preparing crosslinked biomaterial compositions for use in tissue augmentation
AT398276B (en) 1989-05-31 1994-11-25 Sorin Biomedica Spa METHOD FOR PREPARING BIOLOGICAL IMPLANTATION MATERIAL
AU4693093A (en) 1992-07-27 1994-02-14 Haemacure Biotech Inc. Biocompatible surgical implant
US6020181A (en) * 1995-05-17 2000-02-01 New York Blood, Inc. Inhibition of thrombus formation by medical related apparatus comprising treating with fibrinolytic matrix metalloproteinase

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1013577A (en) * 1962-05-11 1965-12-15 Biotest Serum Institut Gmbh A process for the modification of proteins
US5804428A (en) * 1992-10-08 1998-09-08 Bristol-Myers Squibb Company Fibrin sealant compositions and methods for utilizing same
US5733545A (en) * 1995-03-03 1998-03-31 Quantic Biomedical Partners Platelet glue wound sealant

Also Published As

Publication number Publication date
EP1178816B1 (en) 2006-06-21
DE60028965T2 (en) 2007-03-29
ATE330621T1 (en) 2006-07-15
EP1178816A2 (en) 2002-02-13
AU4348800A (en) 2000-11-21
US7015198B1 (en) 2006-03-21
DE60028965D1 (en) 2006-08-03
CA2371265A1 (en) 2000-11-16
WO2000067774A2 (en) 2000-11-16

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