WO2000064977A8 - In situ forming hydrogels - Google Patents

In situ forming hydrogels

Info

Publication number
WO2000064977A8
WO2000064977A8 PCT/US2000/011691 US0011691W WO0064977A8 WO 2000064977 A8 WO2000064977 A8 WO 2000064977A8 US 0011691 W US0011691 W US 0011691W WO 0064977 A8 WO0064977 A8 WO 0064977A8
Authority
WO
WIPO (PCT)
Prior art keywords
situ forming
forming hydrogels
methods
situ
hydrogel
Prior art date
Application number
PCT/US2000/011691
Other languages
French (fr)
Other versions
WO2000064977A1 (en
Inventor
Jeffrey A Hubbell
Julia A Kornfield
Giyoong Tae
Original Assignee
California Inst Of Techn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by California Inst Of Techn filed Critical California Inst Of Techn
Priority to AU49778/00A priority Critical patent/AU4977800A/en
Priority to EP00931980A priority patent/EP1173517A4/en
Publication of WO2000064977A1 publication Critical patent/WO2000064977A1/en
Publication of WO2000064977A8 publication Critical patent/WO2000064977A8/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/02—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques
    • C08J3/03—Making solutions, dispersions, lattices or gels by other methods than by solution, emulsion or suspension polymerisation techniques in aqueous media
    • C08J3/075—Macromolecular gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/74—Synthetic polymeric materials
    • A61K31/765—Polymers containing oxygen
    • A61K31/77—Polymers containing oxygen of oxiranes
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08L—COMPOSITIONS OF MACROMOLECULAR COMPOUNDS
    • C08L5/00—Compositions of polysaccharides or of their derivatives not provided for in groups C08L1/00 or C08L3/00
    • C08L5/16—Cyclodextrin; Derivatives thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Dispersion Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Materials For Medical Uses (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

The invention features materials and methods for the liquid to solid transition of an injectable pre-hydrogel composition to a hydrogel. These methods can be carried out in situ.
PCT/US2000/011691 1999-04-26 2000-04-26 In situ forming hydrogels WO2000064977A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU49778/00A AU4977800A (en) 1999-04-26 2000-04-26 (in situ) forming hydrogels
EP00931980A EP1173517A4 (en) 1999-04-26 2000-04-26 In situ forming hydrogels

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US13116499P 1999-04-26 1999-04-26
US60/133,164 1999-04-26

Publications (2)

Publication Number Publication Date
WO2000064977A1 WO2000064977A1 (en) 2000-11-02
WO2000064977A8 true WO2000064977A8 (en) 2001-05-03

Family

ID=36423498

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/011691 WO2000064977A1 (en) 1999-04-26 2000-04-26 In situ forming hydrogels

Country Status (3)

Country Link
EP (1) EP1173517A4 (en)
AU (1) AU4977800A (en)
WO (1) WO2000064977A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486558B2 (en) 2003-03-27 2016-11-08 Locate Therapeutics Limited Porous matrix

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60033633T2 (en) * 1999-12-08 2007-11-15 Vercell Biotechnology Bv POLYACRYLAMIDIC KIT FOR THE PRODUCTION OF A CAPSULE IN THE TISSUE OF ANIMAL MORGANISM AND ANIMAL ALLOGENIC OR XENOGENIC CELLS, FOR THE TREATMENT OF ONCOLOGICAL DISEASES AND DIABETES MELLITUS
US6652883B2 (en) 2000-03-13 2003-11-25 Biocure, Inc. Tissue bulking and coating compositions
EP1263803B1 (en) 2000-03-13 2007-09-19 BioCure, Inc. Embolic compositions
SG98393A1 (en) 2000-05-19 2003-09-19 Inst Materials Research & Eng Injectable drug delivery systems with cyclodextrin-polymer based hydrogels
US20020122771A1 (en) * 2000-09-23 2002-09-05 Troy Holland Spray hydrogel wound dressings
JP4723244B2 (en) 2002-07-19 2011-07-13 オメロス コーポレイション Biodegradable triblock copolymers, methods for their synthesis, and hydrogels and biomaterials made therefrom
JP2006521180A (en) 2003-03-25 2006-09-21 バイオキュア・インコーポレーテッド Medical device with hydrogel yarn
AU2005260646A1 (en) 2004-06-29 2006-01-12 Bruktawit T. Asfaw Biomaterial
WO2007120818A2 (en) * 2006-04-12 2007-10-25 Massachusetts Institute Of Technology Compositions and methods for inhibiting adhesions
EP2280739B1 (en) 2008-06-03 2012-07-04 Actamax Surgical Materials LLC A tissue coating for preventing undesired tissue-to-tissue adhesions
US9232805B2 (en) 2010-06-29 2016-01-12 Biocure, Inc. In-situ forming hydrogel wound dressings containing antimicrobial agents
JP6712081B2 (en) * 2015-03-10 2020-06-17 国立大学法人 東京大学 Method for producing low-concentration gel using gel precursor cluster, and gel obtained by the method
AU2016353355B9 (en) 2015-11-12 2022-09-29 Graybug Vision, Inc. Aggregating microparticles for therapy
RU2019133337A (en) 2017-03-23 2021-04-23 Грейбуг Вижн, Инк. DRUGS AND COMPOSITIONS FOR THE TREATMENT OF EYE DISORDERS
MX2019013363A (en) 2017-05-10 2020-01-13 Graybug Vision Inc Extended release microparticles and suspensions thereof for medical therapy.
CN112898584B (en) * 2021-01-21 2022-03-08 中国科学院苏州纳米技术与纳米仿生研究所 Solid-solid supermolecule phase change material and preparation method and application thereof
CN113143851A (en) * 2021-03-02 2021-07-23 复旦大学 Solvent exchange-based injectable hydrogel and preparation method and application thereof
CN114425101B (en) * 2022-01-21 2022-07-22 北京大学口腔医学院 Micro-nano double-layer structure antibacterial bracket and preparation method and application thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5560929A (en) * 1986-08-18 1996-10-01 The Dow Chemical Company Structured copolymers and their use as absorbents, gels and carriers of metal ions
US4938763B1 (en) * 1988-10-03 1995-07-04 Atrix Lab Inc Biodegradable in-situ forming implants and method of producing the same
AU2638795A (en) * 1994-06-17 1996-01-15 University Of Nebraska Board Of Regents In situ gel-forming delivery vehicle for bio-affecting substances, and method of use
US5976648A (en) * 1995-12-14 1999-11-02 Kimberly-Clark Worldwide, Inc. Synthesis and use of heterogeneous polymer gels

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US9486558B2 (en) 2003-03-27 2016-11-08 Locate Therapeutics Limited Porous matrix

Also Published As

Publication number Publication date
AU4977800A (en) 2000-11-10
WO2000064977A1 (en) 2000-11-02
EP1173517A4 (en) 2006-06-28
EP1173517A1 (en) 2002-01-23

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