WO2000059933A3 - HUMAN MESENCHYMAL DNAs AND EXPRESSION PRODUCTS - Google Patents

HUMAN MESENCHYMAL DNAs AND EXPRESSION PRODUCTS Download PDF

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Publication number
WO2000059933A3
WO2000059933A3 PCT/US2000/008751 US0008751W WO0059933A3 WO 2000059933 A3 WO2000059933 A3 WO 2000059933A3 US 0008751 W US0008751 W US 0008751W WO 0059933 A3 WO0059933 A3 WO 0059933A3
Authority
WO
WIPO (PCT)
Prior art keywords
human mesenchymal
polypeptides
dnas
expression products
disclosed
Prior art date
Application number
PCT/US2000/008751
Other languages
French (fr)
Other versions
WO2000059933A2 (en
Inventor
Den Bos Christian Van
Gabriel Mbalaviele
Original Assignee
Osiris Therapeutics Inc
Den Bos Christian Van
Gabriel Mbalaviele
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Osiris Therapeutics Inc, Den Bos Christian Van, Gabriel Mbalaviele filed Critical Osiris Therapeutics Inc
Priority to AU43293/00A priority Critical patent/AU4329300A/en
Priority to EP00923114A priority patent/EP1163338A2/en
Priority to JP2000609443A priority patent/JP2002540782A/en
Publication of WO2000059933A2 publication Critical patent/WO2000059933A2/en
Publication of WO2000059933A3 publication Critical patent/WO2000059933A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

A human mesenchymal stem cell (hMSC) cDNAs and putative polypeptides derived from Open Reading Frames contained therein are disclosed. Also disclosed are methods for utilizing the polynucleotides and polypeptides, including use as reagents for chromosomal mapping and identification, DNA fingerprinting and the possible role played by genetic mutations in the disease process, and for the generation of polyclonal and/or monoclonal antibodies specific for said polypeptides.
PCT/US2000/008751 1999-04-01 2000-03-31 HUMAN MESENCHYMAL DNAs AND EXPRESSION PRODUCTS WO2000059933A2 (en)

Priority Applications (3)

Application Number Priority Date Filing Date Title
AU43293/00A AU4329300A (en) 1999-04-01 2000-03-31 Human mesenchymal dnas and expression products
EP00923114A EP1163338A2 (en) 1999-04-01 2000-03-31 HUMAN MESENCHYMAL DNAs AND EXPRESSION PRODUCTS
JP2000609443A JP2002540782A (en) 1999-04-01 2000-03-31 Human mesenchymal DNAs and expression products

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US12741899P 1999-04-01 1999-04-01
US14880099P 1999-08-13 1999-08-13
US60/148,800 1999-08-13
US60/127,418 1999-08-13

Publications (2)

Publication Number Publication Date
WO2000059933A2 WO2000059933A2 (en) 2000-10-12
WO2000059933A3 true WO2000059933A3 (en) 2001-02-15

Family

ID=26825607

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/008751 WO2000059933A2 (en) 1999-04-01 2000-03-31 HUMAN MESENCHYMAL DNAs AND EXPRESSION PRODUCTS

Country Status (4)

Country Link
EP (1) EP1163338A2 (en)
JP (1) JP2002540782A (en)
AU (1) AU4329300A (en)
WO (1) WO2000059933A2 (en)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7227007B2 (en) 2000-12-28 2007-06-05 Asahi Kasei Pharma Corporation NF-κB activating gene
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
US9617506B2 (en) 2013-11-16 2017-04-11 Terumo Bct, Inc. Expanding cells in a bioreactor
EP3613841B1 (en) 2014-03-25 2022-04-20 Terumo BCT, Inc. Passive replacement of media
CN106715676A (en) 2014-09-26 2017-05-24 泰尔茂比司特公司 Scheduled feed
WO2017004592A1 (en) 2015-07-02 2017-01-05 Terumo Bct, Inc. Cell growth with mechanical stimuli
US11965175B2 (en) 2016-05-25 2024-04-23 Terumo Bct, Inc. Cell expansion
US11104874B2 (en) 2016-06-07 2021-08-31 Terumo Bct, Inc. Coating a bioreactor
US11685883B2 (en) 2016-06-07 2023-06-27 Terumo Bct, Inc. Methods and systems for coating a cell growth surface
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion
US11702634B2 (en) 2017-03-31 2023-07-18 Terumo Bct, Inc. Expanding cells in a bioreactor

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035022A1 (en) * 1997-02-06 1998-08-13 Osiris Therapeutics, Inc. p21?CIP1 OR p27KIP1¿ EFFECTS ON THE REGULATION OF DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1998035022A1 (en) * 1997-02-06 1998-08-13 Osiris Therapeutics, Inc. p21?CIP1 OR p27KIP1¿ EFFECTS ON THE REGULATION OF DIFFERENTIATION OF HUMAN MESENCHYMAL STEM CELLS

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
HILLIER L. ET AL.: "yy27e09.s1 Soares melanocyte 2NbHM Homo sapiens cDNA clone IMAGE:272488 3', mrna sequence", EMBL DATABASE , ACCESSION NUMBER N33854, 13 January 1996 (1996-01-13), XP002143787 *
JAISWAL N ET AL: "Osteogenic differentiation of purified, culture-expanded human mesenchymal stem cells in vitro.", JOURNAL OF CELLULAR BIOCHEMISTRY, FEB 1997, 64 (2) P295-312, UNITED STATES, XP000929561 *
JANG WONHEE ET AL: "Aup1, a novel gene on mouse chromosome 6 and human chromosome 2p13.", GENOMICS, vol. 36, no. 2, 1996, pages 366 - 368, XP000929549, ISSN: 0888-7543 *
ROBERT STRAUSBERG: "tm56a07.x1 NCI_CGAP_Kid11 Homo sapiens cDNA clone IMAGE:2162100 3', mRNA sequence", EMBL DATABASE , ACCESSION NUMBER AI479234, 17 March 1999 (1999-03-17), XP002143786 *

Also Published As

Publication number Publication date
EP1163338A2 (en) 2001-12-19
WO2000059933A2 (en) 2000-10-12
JP2002540782A (en) 2002-12-03
AU4329300A (en) 2000-10-23

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