WO2000059550A3 - Indium-114m and related compositions applicable in brachytherapie - Google Patents

Indium-114m and related compositions applicable in brachytherapie Download PDF

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Publication number
WO2000059550A3
WO2000059550A3 PCT/US2000/007855 US0007855W WO0059550A3 WO 2000059550 A3 WO2000059550 A3 WO 2000059550A3 US 0007855 W US0007855 W US 0007855W WO 0059550 A3 WO0059550 A3 WO 0059550A3
Authority
WO
WIPO (PCT)
Prior art keywords
indium
brachytherapie
related compositions
114min
kev
Prior art date
Application number
PCT/US2000/007855
Other languages
French (fr)
Other versions
WO2000059550A2 (en
Inventor
Saed Mirzadeh
W Scott Aaron
Lee Zevenbergen
Original Assignee
Ut Battelle Llc
Saed Mirzadeh
W Scott Aaron
Lee Zevenbergen
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ut Battelle Llc, Saed Mirzadeh, W Scott Aaron, Lee Zevenbergen filed Critical Ut Battelle Llc
Priority to AU41763/00A priority Critical patent/AU4176300A/en
Publication of WO2000059550A2 publication Critical patent/WO2000059550A2/en
Publication of WO2000059550A3 publication Critical patent/WO2000059550A3/en

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A61K51/1282—Devices used in vivo and carrying the radioactive therapeutic or diagnostic agent, therapeutic or in vivo diagnostic kits, stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A61N5/1001—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy using radiation sources introduced into or applied onto the body; brachytherapy
    • A61N2005/1019—Sources therefor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Optics & Photonics (AREA)
  • Epidemiology (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Radiation-Therapy Devices (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

The preparation of a very fine wire of a homogenous alloy of indium and aluminum of up to ∩17 weight percent of indium-113 or -114m (∩0.3 mm in thickness) for use as a brachytherapy source is disclosed. Also disclosed are methods and compositions of 114mIn for brachytherapy. The 114mIn isotope has a half-life of 49.5 days, an average β-particle energy of 773 keV, and a dose rate of 1.66 rad.g.νCi?-1.h-1. 114m¿In emits a gamma-ray at 190 keV with 16 % intensity useful in diagnostics.
PCT/US2000/007855 1999-04-02 2000-03-24 Indium-114m and related compositions applicable in brachytherapie WO2000059550A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU41763/00A AU4176300A (en) 1999-04-02 2000-03-24 Indium-114m as a source for brachytherapy and related compositions and methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US28560699A 1999-04-02 1999-04-02
US09/285,606 1999-04-02

Publications (2)

Publication Number Publication Date
WO2000059550A2 WO2000059550A2 (en) 2000-10-12
WO2000059550A3 true WO2000059550A3 (en) 2001-04-05

Family

ID=23094981

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/007855 WO2000059550A2 (en) 1999-04-02 2000-03-24 Indium-114m and related compositions applicable in brachytherapie

Country Status (2)

Country Link
AU (1) AU4176300A (en)
WO (1) WO2000059550A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1128872B1 (en) 1999-09-14 2004-11-10 Nucletron B.V. Radioactive brachytherapy source and material and manufacturing method therefore
GB0104383D0 (en) 2001-02-22 2001-04-11 Psimedica Ltd Cancer Treatment

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505888A (en) * 1983-05-27 1985-03-19 E. I. Du Pont De Nemours & Company Tracer for circulation determinations
US5163896A (en) * 1988-07-28 1992-11-17 Best Industries, Inc. Pellet for a radioactive seed
US5342283A (en) * 1990-08-13 1994-08-30 Good Roger R Endocurietherapy
WO2000053234A1 (en) * 1999-03-09 2000-09-14 Thomas Jefferson University Lipid soluble radioactive metal chelates for tumor therapy

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4505888A (en) * 1983-05-27 1985-03-19 E. I. Du Pont De Nemours & Company Tracer for circulation determinations
US5163896A (en) * 1988-07-28 1992-11-17 Best Industries, Inc. Pellet for a radioactive seed
US5342283A (en) * 1990-08-13 1994-08-30 Good Roger R Endocurietherapy
WO2000053234A1 (en) * 1999-03-09 2000-09-14 Thomas Jefferson University Lipid soluble radioactive metal chelates for tumor therapy

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
R.W. ARNOLD ET AL.: "COMPARISON OF 99MTC COMPLEX", JOURNAL OF NUCLEAR MEDICINE, vol. 16, no. 5, May 1975 (1975-05-01), NEW YORK US, pages 357 - 367, XP002155648 *

Also Published As

Publication number Publication date
AU4176300A (en) 2000-10-23
WO2000059550A2 (en) 2000-10-12

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