WO2000056860A3 - Diagnosis and therapy of bone conditions - Google Patents

Diagnosis and therapy of bone conditions Download PDF

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Publication number
WO2000056860A3
WO2000056860A3 PCT/GB2000/000948 GB0000948W WO0056860A3 WO 2000056860 A3 WO2000056860 A3 WO 2000056860A3 GB 0000948 W GB0000948 W GB 0000948W WO 0056860 A3 WO0056860 A3 WO 0056860A3
Authority
WO
WIPO (PCT)
Prior art keywords
diagnosis
therapy
bone conditions
bone
conditions
Prior art date
Application number
PCT/GB2000/000948
Other languages
French (fr)
Other versions
WO2000056860A2 (en
Inventor
Harish Datta
Original Assignee
Univ Newcastle Ventures Ltd
Harish Datta
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Newcastle Ventures Ltd, Harish Datta filed Critical Univ Newcastle Ventures Ltd
Priority to AU33034/00A priority Critical patent/AU3303400A/en
Publication of WO2000056860A2 publication Critical patent/WO2000056860A2/en
Publication of WO2000056860A3 publication Critical patent/WO2000056860A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Rheumatology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention relates to the diagnosis and therapy of bone conditions following identification of at least part of the TCR receptor complex expressed in an osteoblast.
PCT/GB2000/000948 1999-03-19 2000-03-17 Diagnosis and therapy of bone conditions WO2000056860A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU33034/00A AU3303400A (en) 1999-03-19 2000-03-17 Bone formation

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9906233.3A GB9906233D0 (en) 1999-03-19 1999-03-19 Bone formation
GB9906233.3 1999-03-19

Publications (2)

Publication Number Publication Date
WO2000056860A2 WO2000056860A2 (en) 2000-09-28
WO2000056860A3 true WO2000056860A3 (en) 2001-01-18

Family

ID=10849876

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/GB2000/000948 WO2000056860A2 (en) 1999-03-19 2000-03-17 Diagnosis and therapy of bone conditions

Country Status (3)

Country Link
AU (1) AU3303400A (en)
GB (1) GB9906233D0 (en)
WO (1) WO2000056860A2 (en)

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05192178A (en) * 1991-07-24 1993-08-03 Idemitsu Kosan Co Ltd Antiosteoclast monoclonal antibody and hybridoma secreting the same antibody
WO1995016038A2 (en) * 1993-12-08 1995-06-15 T Cell Sciences, Inc. Humanized antibodies and uses thereof
WO1996032469A1 (en) * 1995-04-10 1996-10-17 Merck & Co., Inc. Method for producing a highly enriched population of osteoclast cells
EP0798374A1 (en) * 1996-03-01 1997-10-01 Matrix Medical B.V. Method for in vitro production of bone
US5766947A (en) * 1988-12-14 1998-06-16 Astra Ab Monoclonal antibodies reactive with an epitope of a Vβ3.1 variable region of a T cell receptor

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5766947A (en) * 1988-12-14 1998-06-16 Astra Ab Monoclonal antibodies reactive with an epitope of a Vβ3.1 variable region of a T cell receptor
JPH05192178A (en) * 1991-07-24 1993-08-03 Idemitsu Kosan Co Ltd Antiosteoclast monoclonal antibody and hybridoma secreting the same antibody
WO1995016038A2 (en) * 1993-12-08 1995-06-15 T Cell Sciences, Inc. Humanized antibodies and uses thereof
WO1996032469A1 (en) * 1995-04-10 1996-10-17 Merck & Co., Inc. Method for producing a highly enriched population of osteoclast cells
EP0798374A1 (en) * 1996-03-01 1997-10-01 Matrix Medical B.V. Method for in vitro production of bone

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
ZHENG H ET AL: "Specific inhibition of cell-surface T-cell receptor expression by antisense oligodeoxynucleotides and its effect on the production of an antigen- specific regulatory T-cells factor", PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES, vol. 86, no. 10, May 1989 (1989-05-01), pages 3758 - 3762, XP002149813 *

Also Published As

Publication number Publication date
WO2000056860A2 (en) 2000-09-28
GB9906233D0 (en) 1999-05-12
AU3303400A (en) 2000-10-09

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