WO2000053774A3 - Metalloproteinases and methods of use therefor - Google Patents
Metalloproteinases and methods of use therefor Download PDFInfo
- Publication number
- WO2000053774A3 WO2000053774A3 PCT/US2000/006237 US0006237W WO0053774A3 WO 2000053774 A3 WO2000053774 A3 WO 2000053774A3 US 0006237 W US0006237 W US 0006237W WO 0053774 A3 WO0053774 A3 WO 0053774A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- metalloproteinases
- methods
- use therefor
- activity
- agents
- Prior art date
Links
- 102000005741 Metalloproteases Human genes 0.000 title abstract 4
- 108010006035 Metalloproteases Proteins 0.000 title abstract 4
- 102000029750 ADAMTS Human genes 0.000 abstract 1
- 108091022879 ADAMTS Proteins 0.000 abstract 1
- 229920001184 polypeptide Polymers 0.000 abstract 1
- 230000002265 prevention Effects 0.000 abstract 1
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 1
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6489—Metalloendopeptidases (3.4.24)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU36226/00A AU3622600A (en) | 1999-03-08 | 2000-03-08 | Metalloproteinases and methods of use therefor |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US26458599A | 1999-03-08 | 1999-03-08 | |
US09/264,585 | 1999-03-08 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000053774A2 WO2000053774A2 (en) | 2000-09-14 |
WO2000053774A3 true WO2000053774A3 (en) | 2001-01-18 |
Family
ID=23006720
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US2000/006237 WO2000053774A2 (en) | 1999-03-08 | 2000-03-08 | Metalloproteinases and methods of use therefor |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU3622600A (en) |
WO (1) | WO2000053774A2 (en) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7220557B2 (en) | 1997-04-24 | 2007-05-22 | Human Genome Sciences, Inc. | METH1 polynucleotides |
SE0100472L (en) * | 2000-02-18 | 2001-08-19 | Hoffmann La Roche | New metalloproteases having thrombospondome domains and nucleic acid compositions encoding these |
CA2408105A1 (en) * | 2000-05-04 | 2001-11-08 | Sugen, Inc. | Novel proteases |
AU2002215312A1 (en) * | 2000-09-29 | 2002-04-08 | Lexicon Genetics Incorporated | Human proteases and polynucleotides encoding the same |
JPWO2002031163A1 (en) * | 2000-10-11 | 2004-02-19 | 財団法人かずさディー・エヌ・エー研究所 | Novel ADAMTS family polypeptide and gene encoding the same |
WO2002033087A2 (en) * | 2000-10-17 | 2002-04-25 | Curagen Corporation | Proteins and nucleic acids encoding same |
ES2212695B1 (en) * | 2001-09-14 | 2005-10-16 | Universidad De Oviedo | ADAMTS-13 HUMAN PROTEIN IDENTIFICATION PROCEDURE. |
ES2201874B1 (en) * | 2001-09-24 | 2005-05-16 | Univesidad De Oviedo | ADAMTS-17 HUMAN PROTEIN IDENTIFICATION PROCEDURE. |
ES2204250B1 (en) * | 2001-09-24 | 2005-08-16 | Universidad De Oviedo | ADAMTS-16 HUMAN PROTEIN IDENTIFICATION PROCEDURE. |
ES2213428B1 (en) * | 2001-09-25 | 2005-11-16 | Universidad De Oviedo. | ADAMTS-19 HUMAN PROTEIN IDENTIFICATION PROCEDURE. |
ES2211256B1 (en) * | 2001-09-28 | 2005-10-16 | Universidad De Oviedo. | ADAMTS-19 HUMAN PROTEIN IDENTIFICATION PROCEDURE. |
ES2205989B1 (en) * | 2001-09-24 | 2005-08-16 | Universidad De Oviedo | ADAMTS-15 HUMAN PROTEIN IDENTIFICATION PROCEDURE. |
AU2003215070A1 (en) | 2002-02-05 | 2003-09-02 | Wyeth | Truncated aggrecanase molecules |
AU2002314999A1 (en) * | 2002-06-06 | 2003-12-22 | The Cleveland Clinic Foundation | Adamts nucleic acids and proteins |
MXPA05000959A (en) | 2002-07-29 | 2005-05-16 | Wyeth Corp | Modified adamts4 molecules and method of use thereof. |
US7696307B2 (en) * | 2004-04-12 | 2010-04-13 | The Trustees Of The University Of Pennsylvania | Function and regulation of ADAMTS-1 |
EP2295570A1 (en) * | 2005-07-27 | 2011-03-16 | Oncotherapy Science, Inc. | Method of diagnosing small cell lung cancer |
US8263072B2 (en) | 2007-06-22 | 2012-09-11 | Genera Istrazivanja, d.o.o. | ADAMTS4 as a blood biomarker and therapeutic target for chronic renal failure |
HUE031089T2 (en) | 2012-04-13 | 2017-06-28 | Rottapharm Biotech Srl | Anti-ADAMTS-5 antibody, derivatives and uses thereof |
WO2015110707A1 (en) * | 2014-01-24 | 2015-07-30 | University Of Helsinki | Methods and uses related to adamts3 |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998055643A1 (en) * | 1997-06-03 | 1998-12-10 | Kureha Chemical Industry Co., Ltd. | Human adamts-1 protein, gene coding for the same, pharmaceutical composition, and method for immunologically assaying human adamts-1 protein |
-
2000
- 2000-03-08 WO PCT/US2000/006237 patent/WO2000053774A2/en active Application Filing
- 2000-03-08 AU AU36226/00A patent/AU3622600A/en not_active Abandoned
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998055643A1 (en) * | 1997-06-03 | 1998-12-10 | Kureha Chemical Industry Co., Ltd. | Human adamts-1 protein, gene coding for the same, pharmaceutical composition, and method for immunologically assaying human adamts-1 protein |
EP1004674A1 (en) * | 1997-06-03 | 2000-05-31 | Kureha Chemical Industry Co., Ltd. | Human adamts-1 protein, gene coding for the same, pharmaceutical composition, and method for immunologically assaying human adamts-1 protein |
Non-Patent Citations (5)
Title |
---|
BOR LUEN TANG ET AL.: "ADAMTS: A novel family of proteases with an ADAM protease domain and thrombospondin 1 repeats", FEBS LETTERS, vol. 445, 26 February 1999 (1999-02-26), AMSTERDAM NL, pages 223 - 225, XP002141413, Retrieved from the Internet <URL:http://gdbwww.gdb.org/gdb-bin/genera/genera/hgd/Gene?!action=query&displayName=ADAMTS2> [retrieved on 20000622] * |
EMBL Database Entry AI378857 Accession number AI378857; 28 January 1999 ROBERT STRAUSBERG:"tc67h11.x1 Soares_NhHMPu_S1 Homo sapiens cDNA clone" * |
FRANCISCA VÁZQUEZ ET AL.: "METH-1, a human ortholog of ADAMTS-1, and METH-2 are members of a new family of proteins with angio-inhibitory activity", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 274, no. 33, 13 August 1999 (1999-08-13), MD US, pages 23349 - 23357, XP002141414 * |
KOUJI KUNO ET AL.: "Molecular cloning of a gene encoding a new type of metalloproteinase-disintegrin family protein with thrombospondin motifs as an inflammation associated gene", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 272, no. 1, 3 January 1997 (1997-01-03), MD US, pages 556 - 562, XP002076038 * |
KOUJI KUNO ET AL.: "The exon/intron organization and chromosomal mapping of the mouse ADAMTS-1 gene encoding an ADAM family protein with TPS motifs", GENOMICS, vol. 46, no. 3, 15 December 1997 (1997-12-15), pages 466 - 471, XP000922766 * |
Also Published As
Publication number | Publication date |
---|---|
WO2000053774A2 (en) | 2000-09-14 |
AU3622600A (en) | 2000-09-28 |
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