WO2000049994A8 - An aqueous non-alcoholic oral rinse containing benzocaine and carbomer - Google Patents

An aqueous non-alcoholic oral rinse containing benzocaine and carbomer

Info

Publication number
WO2000049994A8
WO2000049994A8 PCT/US2000/004442 US0004442W WO0049994A8 WO 2000049994 A8 WO2000049994 A8 WO 2000049994A8 US 0004442 W US0004442 W US 0004442W WO 0049994 A8 WO0049994 A8 WO 0049994A8
Authority
WO
WIPO (PCT)
Prior art keywords
carbomer
oral rinse
benzocaine
aqueous non
rinse containing
Prior art date
Application number
PCT/US2000/004442
Other languages
French (fr)
Other versions
WO2000049994A1 (en
Inventor
Robert L Ibsen
Alan Matthews
Thomas C Chadwick
Rachel Pineda
Original Assignee
Den Mat Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Den Mat Corp filed Critical Den Mat Corp
Priority to AU32390/00A priority Critical patent/AU3239000A/en
Priority to EP00910268A priority patent/EP1154749A4/en
Publication of WO2000049994A1 publication Critical patent/WO2000049994A1/en
Publication of WO2000049994A8 publication Critical patent/WO2000049994A8/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
    • A61K31/235—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group
    • A61K31/24—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids having an aromatic ring attached to a carboxyl group having an amino or nitro group
    • A61K31/245—Amino benzoic acid types, e.g. procaine, novocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • A61K8/445—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof aromatic, i.e. the carboxylic acid directly linked to the aromatic ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8147—Homopolymers or copolymers of acids; Metal or ammonium salts thereof, e.g. crotonic acid, (meth)acrylic acid; Compositions of derivatives of such polymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
    • A61K8/81—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions involving only carbon-to-carbon unsaturated bonds
    • A61K8/8141—Compositions of homopolymers or copolymers of compounds having one or more unsaturated aliphatic radicals, each having only one carbon-to-carbon double bond, and at least one being terminated by only one carboxyl radical, or of salts, anhydrides, esters, amides, imides or nitriles thereof; Compositions of derivatives of such polymers
    • A61K8/8152—Homopolymers or copolymers of esters, e.g. (meth)acrylic acid esters; Compositions of derivatives of such polymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Emergency Medicine (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Cosmetics (AREA)

Abstract

A transparent, alcohol-free, aqueous oral rinse composition comprising more than 0.04 % by weight benzocaine, carbomer in an amount that is roughly equal to half the amount of benzocaine employed, and water. The composition relieves the soreness of aphthous ulcers and similar mouth sores.
PCT/US2000/004442 1999-02-23 2000-02-23 An aqueous non-alcoholic oral rinse containing benzocaine and carbomer WO2000049994A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU32390/00A AU3239000A (en) 1999-02-23 2000-02-23 An aqueous non-alcoholic oral rinse containing benzocaine and carbomer
EP00910268A EP1154749A4 (en) 1999-02-23 2000-02-23 An aqueous non-alcoholic oral rinse containing benzocaine and carbomer

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12143099P 1999-02-23 1999-02-23
US60/121,430 1999-02-23

Publications (2)

Publication Number Publication Date
WO2000049994A1 WO2000049994A1 (en) 2000-08-31
WO2000049994A8 true WO2000049994A8 (en) 2001-03-29

Family

ID=22396684

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2000/004442 WO2000049994A1 (en) 1999-02-23 2000-02-23 An aqueous non-alcoholic oral rinse containing benzocaine and carbomer

Country Status (3)

Country Link
EP (1) EP1154749A4 (en)
AU (1) AU3239000A (en)
WO (1) WO2000049994A1 (en)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BRPI0704542B8 (en) * 2007-05-15 2021-05-25 Univ Estadual Campinas Unicamp pharmaceutical composition, process for obtaining the pharmaceutical composition, use of a pharmaceutically effective amount of anesthetic and gelling agent, product and method of treatment
JP2013532119A (en) * 2010-04-21 2013-08-15 テイコク ファーマ ユーエスエー インコーポレーテッド Local anesthetic emulsion composition and methods of making and using the composition
BR112014014315B1 (en) 2011-12-15 2018-07-03 Colgate-Palmolive Company Aqueous oral hygiene composition and use

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3594467A (en) * 1968-10-09 1971-07-20 Richardson Merrell Inc Long-lasting troche
US5446063A (en) * 1986-10-30 1995-08-29 American Home Products Corporation Anesthetic compositions
US5547657A (en) * 1994-10-11 1996-08-20 Eastman Chemical Company Low-irritation anesthetic and antiseptic mouth rinse
US5994383A (en) * 1997-11-18 1999-11-30 Woodward Laboratories, Inc. Surfactant-based antimicrobial compositions and methods for using the same

Also Published As

Publication number Publication date
AU3239000A (en) 2000-09-14
WO2000049994A1 (en) 2000-08-31
EP1154749A1 (en) 2001-11-21
EP1154749A4 (en) 2006-01-04

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